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CN111603685A - Near-infrared light fundus therapy device - Google Patents

Near-infrared light fundus therapy device Download PDF

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Publication number
CN111603685A
CN111603685A CN202010542370.3A CN202010542370A CN111603685A CN 111603685 A CN111603685 A CN 111603685A CN 202010542370 A CN202010542370 A CN 202010542370A CN 111603685 A CN111603685 A CN 111603685A
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infrared light
light source
controller
fundus
infrared
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曲超
赵辉
史超强
王欣
陈立波
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University of Electronic Science and Technology of China
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University of Electronic Science and Technology of China
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/04Eye-masks ; Devices to be worn on the face, not intended for looking through; Eye-pads for sunbathing
    • A61F9/045Eye-shades or visors; Shields beside, between or below the eyes
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K7/00Constructional details common to different types of electric apparatus
    • H05K7/20Modifications to facilitate cooling, ventilating, or heating
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K7/00Constructional details common to different types of electric apparatus
    • H05K7/20Modifications to facilitate cooling, ventilating, or heating
    • H05K7/20009Modifications to facilitate cooling, ventilating, or heating using a gaseous coolant in electronic enclosures
    • H05K7/20136Forced ventilation, e.g. by fans
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K7/00Constructional details common to different types of electric apparatus
    • H05K7/20Modifications to facilitate cooling, ventilating, or heating
    • H05K7/20218Modifications to facilitate cooling, ventilating, or heating using a liquid coolant without phase change in electronic enclosures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • A61N2005/0647Applicators worn by the patient the applicator adapted to be worn on the head
    • A61N2005/0648Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Biomedical Technology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
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Abstract

A near infrared light eyeground therapeutic instrument relates to the technical field of medical instruments for eye diseases. The near-infrared light eye ground therapeutic instrument comprises a head-mounted main body and a controller, wherein a near-infrared light source electrically connected with the controller is arranged on the head-mounted main body and used for irradiating the eye ground of a user to be detected, the near-infrared light source is provided with a plurality of preset light emitting powers, and the controller is used for controlling the near-infrared light source to select the corresponding preset light emitting power so as to be matched with the eye ground disease condition of the user to be detected. The near-infrared light fundus therapeutic apparatus can conveniently and effectively assist in treating fundus diseases such as eye central serous chorioretinopathy, senile macular degeneration and the like.

Description

近红外光眼底治疗仪Near-infrared light fundus therapy device

技术领域technical field

本发明涉及眼部疾病的医疗器械技术领域,具体而言,涉及一种近红外光眼底治疗仪。The invention relates to the technical field of medical devices for eye diseases, in particular to a near-infrared light fundus therapy apparatus.

背景技术Background technique

眼底由视网膜、眼底血管、视神经乳头、视神经纤维、视网膜上的黄斑部,以及视网膜后的脉络膜等构成,这些部位的病变统称为眼底病,眼底病对人的危害主要是影响视觉能力,严重的可致盲。目前,眼底病传统的治疗方法有药物治疗和物理治疗,但往往难以奏效。当激光自首次运用于眼科视网膜脱离的照射开始,由于激光具有波长一致性、方向性好等优点,可通过屈光间质针对眼球的不同目标组织准确地发挥作用,所以激光在医学领域中首先应用于眼科,而且最为深入。The fundus is composed of the retina, fundus blood vessels, optic nerve head, optic nerve fibers, the macula on the retina, and the choroid behind the retina. The lesions in these parts are collectively referred to as fundus diseases. The harm of fundus diseases to people is mainly to affect the visual ability. Can cause blindness. At present, traditional treatment methods for fundus diseases include drug therapy and physical therapy, but they are often ineffective. When the laser was first used in the irradiation of retinal detachment in ophthalmology, because the laser has the advantages of wavelength consistency and good directionality, it can accurately play a role in different target tissues of the eyeball through the refractive interstitium, so the laser is the first in the medical field. Used in ophthalmology, and most deeply.

目前国内外普遍采用激光作为光源进行眼底治疗,然而,由于激光的特性,采用激光治疗眼底疾病在临床上使用时仍然存在几个问题:首先是激光眼底治疗仪必须由临床眼科医生操作,在眼底镜的引导下开展。对医生来讲存在精细操作、治疗耗时长等问题;对患者而言,必须到院就医,时间成本和经济成本相对较高。其次,激光照射光斑较小,一般在3mm2左右,适合于单点病灶的治疗,医生需要对每个病灶至少进行10min的照射,其治疗时间也随着病灶数量而增加。At present, laser is widely used as a light source for fundus treatment at home and abroad. However, due to the characteristics of laser, there are still several problems in clinical use of laser treatment of fundus diseases: First, the laser fundus treatment instrument must be operated by a clinical ophthalmologist. under the guidance of the mirror. For doctors, there are problems such as fine operation and long treatment time; for patients, it is necessary to go to the hospital for medical treatment, and the time cost and economic cost are relatively high. Secondly, the laser irradiation spot is small, generally about 3mm 2 , which is suitable for the treatment of single-point lesions. Doctors need to irradiate each lesion for at least 10 minutes, and the treatment time also increases with the number of lesions.

发明内容SUMMARY OF THE INVENTION

本发明的目的在于提供一种近红外光眼底治疗仪,该近红外光眼底治疗仪能够能方便、有效地辅助治疗眼中心性浆液性视网膜脉络膜病变、老年性黄斑变性等眼底疾病。The purpose of the present invention is to provide a near-infrared light fundus therapeutic apparatus, which can conveniently and effectively assist in the treatment of central serous retinal choroidopathy, age-related macular degeneration and other fundus diseases.

本发明的实施例是这样实现的:Embodiments of the present invention are implemented as follows:

本发明提供一种近红外光眼底治疗仪,该近红外光眼底治疗仪包括头戴式主体和控制器,所述头戴式主体上设有与所述控制器电连接的近红外光源,所述近红外光源用于照射被测用户的眼底,所述近红外光源具有多个预设出光功率,所述控制器用于控制所述近红外光源选择对应的所述预设出光功率,以与所述被测用户的眼底疾病情况相适配。该近红外光眼底治疗仪能够能方便、有效地辅助治疗眼中心性浆液性视网膜脉络膜病变、老年性黄斑变性等眼底疾病。The present invention provides a near-infrared light fundus therapy apparatus, which comprises a head-mounted main body and a controller, wherein a near-infrared light source electrically connected to the controller is provided on the head-mounted main body, so that the The near-infrared light source is used to illuminate the fundus of the user under test, the near-infrared light source has a plurality of preset light output powers, and the controller is used to control the near-infrared light source to select the corresponding preset light output power to match the preset light output power. It is suitable for the fundus disease of the tested user. The near-infrared light fundus therapy apparatus can conveniently and effectively assist in the treatment of fundus diseases such as central serous retinal choroidopathy and age-related macular degeneration.

可选地,所述近红外光源为LED光源。Optionally, the near-infrared light source is an LED light source.

可选地,所述近红外光源的波长在760nm至850nm之间。Optionally, the wavelength of the near-infrared light source is between 760 nm and 850 nm.

可选地,所述近红外光源的光功率密度在100mW/cm2至600mW/cm2之间。Optionally, the optical power density of the near-infrared light source is between 100 mW/cm 2 and 600 mW/cm 2 .

可选地,所述近红外光源与所述被测用户的眼球角膜之间的距离在18mm至24mm之间。Optionally, the distance between the near-infrared light source and the cornea of the user's eyeball is between 18mm and 24mm.

可选地,所述近红外光眼底治疗仪还包括聚光筒,所述聚光筒设于所述头戴式主体靠近所述近红外光源处,用于对所述近红外光源发射的所述近红外光进行汇聚。Optionally, the near-infrared light fundus therapy apparatus further includes a condensing tube, which is arranged on the head-mounted main body near the near-infrared light source, and is used for all the light emitted by the near-infrared light source. The near-infrared light is converged.

可选地,所述近红外光源包括呈并列设置的第一光源和第二光源,所述第一光源和所述第二光源分别对应照射所述被测用户的左眼和右眼,且所述第一光源和所述第二光源分别和所述控制器电连接。Optionally, the near-infrared light source includes a first light source and a second light source arranged in parallel, the first light source and the second light source respectively illuminate the left eye and the right eye of the user under test, and the The first light source and the second light source are respectively electrically connected to the controller.

可选地,所述近红外光眼底治疗仪还包括散热装置,所述散热装置与所述控制器电连接,用于对所述近红外光源进行散热。Optionally, the near-infrared light fundus therapy apparatus further includes a heat dissipation device, and the heat dissipation device is electrically connected to the controller for dissipating heat from the near-infrared light source.

可选地,所述近红外光眼底治疗仪还包括与所述控制器电连接的定时器,所述控制器用于根据接收到的所述定时器的定时信息控制所述控制器与所述近红外光源之间的连接电路断开。Optionally, the near-infrared light fundus therapy apparatus further includes a timer electrically connected to the controller, and the controller is configured to control the controller and the near-infrared according to the received timing information of the timer. The connection circuit between the infrared light sources is broken.

可选地,所述近红外光眼底治疗仪还包括显示装置,所述显示装置与所述控制器电连接,用于显示所述近红外光源的出光功率和所述定时器的定时时间。Optionally, the near-infrared light fundus therapy apparatus further includes a display device, which is electrically connected to the controller and used to display the light output power of the near-infrared light source and the timing time of the timer.

可选地,所述近红外光眼底治疗仪还包括与所述控制器电连接的紧急断电装置,所述控制器用于根据接收到的所述紧急断电装置的断电信息控制所述控制器与所述近红外光源之间的连接电路断开。Optionally, the near-infrared light fundus therapy apparatus further includes an emergency power-off device electrically connected to the controller, and the controller is configured to control the control according to the received power-off information of the emergency power-off device. The connection circuit between the device and the near-infrared light source is disconnected.

本发明的有益效果包括:The beneficial effects of the present invention include:

本申请提供一种近红外光眼底治疗仪,该近红外光眼底治疗仪包括头戴式主体和控制器,头戴式主体上设有与控制器电连接的近红外光源,近红外光源用于照射被测用户的眼底,近红外光源具有多个预设出光功率,控制器用于控制近红外光源选择对应的预设出光功率,以与被测用户的眼底疾病情况相适配。这样一来,本申请可根据被测用户的眼底疾病情况通过控制器选择与被测用户的眼底疾病相适配的近红外光源的预设出光功率,以控制近红外光源发射对应出光功率的近红外光线,该近红外光线通过照射被测用户的眼球,透过眼球的屈光间质,将近红外光线的能量传入被测用户的眼底,针对眼底不同的目标组织发挥作用,以治疗与线粒体功能衰减有关的眼底疾病。本申请的近红外光眼底治疗仪,通过头戴式主体可将近红外光眼底治疗仪佩戴于被测用户的头部,且通过选择与被测用户的眼底疾病情况相适配的预设出光功率,能够能方便、有效且针对性地辅助治疗眼中心性浆液性视网膜脉络膜病变、老年性黄斑变性等眼底疾病。The present application provides a near-infrared light fundus therapy device, the near-infrared light fundus therapy device includes a head-mounted main body and a controller, the head-mounted main body is provided with a near-infrared light source that is electrically connected to the controller, and the near-infrared light source is used for To illuminate the fundus of the user under test, the near-infrared light source has multiple preset light output powers, and the controller is used to control the near-infrared light source to select the corresponding preset light output power to match the fundus disease of the tested user. In this way, the present application can select the preset light output power of the near-infrared light source that is suitable for the fundus disease of the tested user through the controller according to the fundus disease of the tested user, so as to control the near-infrared light source to emit a near-infrared light source corresponding to the light output power. Infrared light, the near-infrared light irradiates the eyeball of the tested user, passes through the refractive interstitium of the eyeball, and the energy of the near-infrared light is transmitted to the fundus of the tested user, and plays a role in different target tissues of the fundus to treat and mitochondria. Fundus diseases related to functional decline. In the near-infrared light fundus therapy apparatus of the present application, the near-infrared light fundus therapy apparatus can be worn on the head of the tested user through the head-mounted main body, and the preset light output power suitable for the fundus disease of the tested user can be selected by selecting the preset light output power. , can be convenient, effective and targeted adjuvant treatment of central ocular serous retinal choroidopathy, age-related macular degeneration and other fundus diseases.

附图说明Description of drawings

为了更清楚地说明本发明实施例的技术方案,下面将对实施例中所需要使用的附图作简单地介绍,应当理解,以下附图仅示出了本发明的某些实施例,因此不应被看作是对范围的限定,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他相关的附图。In order to illustrate the technical solutions of the embodiments of the present invention more clearly, the following briefly introduces the accompanying drawings used in the embodiments. It should be understood that the following drawings only show some embodiments of the present invention, and therefore do not It should be regarded as a limitation of the scope, and for those of ordinary skill in the art, other related drawings can also be obtained according to these drawings without any creative effort.

图1为本发明实施例提供的近红外光眼底治疗仪的结构示意图之一;1 is one of the structural schematic diagrams of a near-infrared light fundus therapy apparatus provided by an embodiment of the present invention;

图2为本发明实施例提供的近红外光眼底治疗仪的结构示意图之二;Fig. 2 is the second structural schematic diagram of a near-infrared light fundus therapy apparatus provided by an embodiment of the present invention;

图3为本发明实施例提供的近红外光眼底治疗仪的结构示意图之三;3 is a third schematic structural diagram of a near-infrared light fundus therapy apparatus provided by an embodiment of the present invention;

图4为本发明实施例提供的近红外光眼底治疗仪的结构示意图之四;4 is a fourth schematic structural diagram of a near-infrared light fundus therapy apparatus provided by an embodiment of the present invention;

图5为本发明实施例提供的近红外光眼底治疗仪的结构示意图之五。FIG. 5 is a fifth schematic structural diagram of a near-infrared light fundus therapy apparatus provided by an embodiment of the present invention.

图标:10-头戴式主体;20-控制器;30-近红外光源;31-第一光源;32-第二光源;40-聚光筒;50-散热装置;60-显示装置;70-定时器;80-紧急断电装置;90-运行指示灯。Icon: 10-head mounted body; 20-controller; 30-near infrared light source; 31-first light source; 32-second light source; 40-concentrator; 50-radiator; 60-display device; 70- Timer; 80-emergency power-off device; 90-running indicator light.

具体实施方式Detailed ways

为使本发明实施例的目的、技术方案和优点更加清楚,下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例是本发明一部分实施例,而不是全部的实施例。通常在此处附图中描述和示出的本发明实施例的组件可以以各种不同的配置来布置和设计。In order to make the purposes, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments These are some embodiments of the present invention, but not all embodiments. The components of the embodiments of the invention generally described and illustrated in the drawings herein may be arranged and designed in a variety of different configurations.

因此,以下对在附图中提供的本发明的实施例的详细描述并非旨在限制要求保护的本发明的范围,而是仅仅表示本发明的选定实施例。基于本发明中的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。Thus, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

应注意到:相似的标号和字母在下面的附图中表示类似项,因此,一旦某一项在一个附图中被定义,则在随后的附图中不需要对其进行进一步定义和解释。It should be noted that like numerals and letters refer to like items in the following figures, so once an item is defined in one figure, it does not require further definition and explanation in subsequent figures.

在本发明的描述中,需要说明的是,术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系,或者是该发明产品使用时惯常摆放的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。此外,术语“第一”、“第二”、“第三”等仅用于区分描述,而不能理解为指示或暗示相对重要性。In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship that the product of the invention is usually placed in use, only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying The device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and therefore should not be construed as limiting the invention. Furthermore, the terms "first", "second", "third", etc. are only used to differentiate the description and should not be construed as indicating or implying relative importance.

此外,术语“水平”、“竖直”等术语并不表示要求部件绝对水平或悬垂,而是可以稍微倾斜。如“水平”仅仅是指其方向相对“竖直”而言更加水平,并不是表示该结构一定要完全水平,而是可以稍微倾斜。Furthermore, the terms "horizontal", "vertical" and the like do not imply that a component is required to be absolutely horizontal or overhang, but rather may be slightly inclined. For example, "horizontal" only means that its direction is more horizontal than "vertical", it does not mean that the structure must be completely horizontal, but can be slightly inclined.

在本发明的描述中,还需要说明的是,除非另有明确的规定和限定,术语“设置”、“安装”、“相连”、“连接”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通。对于本领域的普通技术人员而言,可以具体情况理解上述术语在本发明中的具体含义。In the description of the present invention, it should also be noted that, unless otherwise expressly specified and limited, the terms "arranged", "installed", "connected" and "connected" should be understood in a broad sense, for example, it may be a fixed connection, It can also be a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or the internal communication between the two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood in specific situations.

近红外光(波长在600nm~1000nm)对组织的愈合有促进作用。通过一系列的动物实验和临床观察,发现近红外光对急性甲醇中毒性视网膜及视神经损伤的功能恢复有一定疗效。其通过促进线粒体功能,提高细胞有氧代谢,从而提高细胞在缺氧和有毒环境下的生存能力,抑制基因变异和突变。由此我们推测近红外光对与线粒体功能衰减有关的眼底疾病,如青少年卵黄囊样黄斑变性等存在类似的疗效。为此,经过临床观察和实验室证实,随着年龄的增加,眼底黄斑区确实存在线粒体和细胞色素氧化酶的功能异常,由于黄斑区的变化比周边部严重,从而推断这可能和光损伤有关。经一直被用来模拟老年性黄斑变性进行前期基础性研究的光损伤的动物模型验证,发现光损伤时氧化物的堆积损伤了视杆细胞线粒体,线粒体功能的失代偿最终导致了视杆细胞的死亡。Near-infrared light (wavelength between 600nm and 1000nm) can promote tissue healing. Through a series of animal experiments and clinical observations, it was found that near-infrared light has a certain effect on the functional recovery of retinal and optic nerve damage in acute methanol poisoning. By promoting mitochondrial function, it improves the aerobic metabolism of cells, thereby improving the viability of cells in hypoxic and toxic environments, and inhibiting gene variation and mutation. Therefore, we speculate that near-infrared light has similar effects on fundus diseases related to mitochondrial function attenuation, such as juvenile yolk sac-like macular degeneration. For this reason, after clinical observation and laboratory confirmation, with the increase of age, the function of mitochondria and cytochrome oxidase does exist in the macular area of the fundus. Since the changes in the macular area are more serious than those in the peripheral area, it is inferred that this may be related to photodamage. It has been verified by an animal model of photodamage that has been used to simulate age-related macular degeneration for early basic research. It is found that the accumulation of oxides during photodamage damages the mitochondria of rod cells, and the decompensation of mitochondrial function eventually leads to rod cells. of death.

基于上述病理基础,本申请为方便、有效地辅助治疗眼底疾病,特此提出一种新型的近红外光眼治疗仪,以解决现有技术中采用激光治疗眼底疾病存在的相关缺陷(例如,到院治疗不便、治疗过程难度大、费用高等)。Based on the above-mentioned pathological basis, in order to facilitate and effectively assist in the treatment of fundus diseases, the present application hereby proposes a new type of near-infrared photoreceptor to solve the related defects in the prior art using lasers to treat fundus diseases (for example, hospitalization Treatment is inconvenient, the treatment process is difficult, and the cost is high).

请参照图1至图5,本实施例提供一种近红外光眼底治疗仪,包括头戴式主体10和控制器20,头戴式主体10上设有与控制器20电连接的近红外光源30,近红外光源30用于照射被测用户的眼底,近红外光源30具有多个预设出光功率,控制器20用于控制近红外光源30选择对应的预设出光功率,以与被测用户的眼底疾病情况相适配。Referring to FIGS. 1 to 5 , the present embodiment provides a near-infrared light fundus therapy apparatus, including a head-mounted main body 10 and a controller 20 . The head-mounted main body 10 is provided with a near-infrared light source that is electrically connected to the controller 20 . 30. The near-infrared light source 30 is used to illuminate the fundus of the user under test. The near-infrared light source 30 has a plurality of preset light output powers. suitable for the condition of the fundus disease.

需要说明的是,第一,通过研究发现,发生光损伤时,氧化物的堆积会损伤视杆细胞线粒体DNA,线粒体功能的失代偿最终导致了视杆细胞的死亡。而近红外光对组织的愈合具有促进作用,可以通过促进线粒体功能,提高细胞的有氧代谢,从而提高细胞在缺氧和有毒环境下的生存能力,抑制基因变异和突变。鉴于近红外光对于线粒体功能的促进作用,本实施例便是通过近红外光源30照射被测用户的眼球,透过眼球的屈光间质,将近红外光线的能量传入被测用户的眼底,针对眼底不同的目标组织发挥作用,以治疗与线粒体功能衰减有关的眼底疾病。在本实施例中,近红外光眼底治疗仪所治疗的眼底疾病包括但不限于眼底损伤性疾病(如外伤导致的视网膜震荡)、黄斑疾病(如中心性浆液性视网膜脉络膜病变和老年性黄斑变性等),慢性线粒体损伤性病变(如卵黄样黄斑变性等)以及眼底出血性疾病(如视网膜静脉阻塞和糖尿病眼底出血等)。It should be noted that, first, it is found through research that when light damage occurs, the accumulation of oxides will damage the mitochondrial DNA of rod cells, and the decompensation of mitochondrial function will eventually lead to the death of rod cells. Near-infrared light can promote the healing of tissues. It can improve the aerobic metabolism of cells by promoting mitochondrial function, thereby improving the survival ability of cells in hypoxic and toxic environments, and inhibiting gene mutation and mutation. In view of the promoting effect of near-infrared light on mitochondrial function, in this embodiment, the near-infrared light source 30 is used to illuminate the eyeball of the user under test, and the energy of the near-infrared light is transmitted to the fundus of the eye of the user under test through the refractive interstitium of the eyeball. It acts on different target tissues of the fundus to treat fundus diseases related to mitochondrial dysfunction. In this embodiment, the fundus diseases treated by the near-infrared light fundus therapy device include but are not limited to fundus damage diseases (such as retinal concussion caused by trauma), macular diseases (such as central serous chorioretinopathies and age-related macular degeneration) etc.), chronic mitochondrial damage lesions (such as vitelloid macular degeneration, etc.) and fundus hemorrhagic diseases (such as retinal vein occlusion and diabetic fundus hemorrhage, etc.).

在本实施例中,近红外光经瞳孔直接照射眼底还可以更有效且安全地发挥其光物理和光化学作用,提高眼底代谢率、血循环,改善眼部组织损伤修复的作用,如增加近视患者视网膜、脉络膜和巩膜血循环和供氧,进而促使成纤维细胞重塑而发挥预防、减缓、阻止甚至逆转近视的作用。也可作用于视功能细胞,增加视功能细胞代谢和血循环,可有效减少功能细胞的损伤和修复,以达到预防、减缓、阻止甚至逆转眼病的作用。In this embodiment, the near-infrared light directly irradiating the fundus through the pupil can also exert its photophysical and photochemical effects more effectively and safely, improve the metabolic rate and blood circulation of the fundus, and improve the repair of eye tissue damage, such as increasing the retinal of myopia patients. , choroid and sclera blood circulation and oxygen supply, and then promote the remodeling of fibroblasts to prevent, slow down, prevent or even reverse myopia. It can also act on visual function cells, increase the metabolism and blood circulation of visual function cells, and effectively reduce the damage and repair of functional cells, so as to prevent, slow down, prevent or even reverse eye diseases.

第二,本实施例提供的头戴式主体10是为了便于用户佩戴,使得本实施例的近红外光眼底治疗仪用户体验更佳。Second, the head-mounted main body 10 provided in this embodiment is convenient for the user to wear, so that the user experience of the near-infrared light fundus therapy apparatus in this embodiment is better.

示例地,该头戴式主体10包括眼罩、前额固定板以及固定带,其中,近红外光源30设于眼罩上,其用于照射被测用户的眼底,优选地,近红外光源30可对应设于被测用户的眼部位置。另外,眼罩和前额固定板连接,固定带和前额固定板和/或眼罩连接。在本实施例中,固定带的松紧度可调节。例如,可采用卡扣调节固定带的松紧度,以使得固定带适用于各种头型的用户,另外,本申请的固定带也可以为松紧带,在此不作限制。应理解,本申请的前额固定板以及眼罩分别与人体前额和眼部形状相适配。For example, the head-mounted body 10 includes an eye mask, a forehead fixing plate and a fixing belt, wherein the near-infrared light source 30 is provided on the eye mask and is used to illuminate the fundus of the user under test. Preferably, the near-infrared light source 30 can be correspondingly provided. on the eye position of the tested user. In addition, the eyecup is connected to the forehead fixing plate, and the fixing strap is connected to the forehead fixing plate and/or the eyecup. In this embodiment, the tightness of the fixing strap is adjustable. For example, a buckle can be used to adjust the tightness of the fixing band, so that the fixing band is suitable for users of various head shapes. In addition, the fixing band of the present application can also be an elastic band, which is not limited here. It should be understood that the forehead fixing plate and the eye mask of the present application are adapted to the shape of the forehead and eyes of the human body, respectively.

第三,近红外光源30用于照射被测用户的眼底。具体地,在本实施例中,上述近红外光源30包括呈并列设置的第一光源31和第二光源32,第一光源31和第二光源32分别对应照射被测用户的左眼和右眼,且第一光源31和第二光源32分别和控制器20电连接。这样一来,用户可根据两只眼睛的不同疾病情况进行针对性治疗,对眼底疾病的治疗效果更佳。应理解,上述第一光源31和第二光源32分别和控制器20电连接的,即控制器20可分别控制第一光源31和第二光源32的开启与关闭,以选择治疗左眼和/或右眼。Third, the near-infrared light source 30 is used to illuminate the fundus of the user under test. Specifically, in this embodiment, the above-mentioned near-infrared light source 30 includes a first light source 31 and a second light source 32 arranged in parallel, and the first light source 31 and the second light source 32 respectively illuminate the left eye and the right eye of the user under test. , and the first light source 31 and the second light source 32 are respectively electrically connected to the controller 20 . In this way, the user can perform targeted treatment according to the different diseases of the two eyes, and the treatment effect on the fundus diseases is better. It should be understood that the above-mentioned first light source 31 and second light source 32 are respectively electrically connected to the controller 20, that is, the controller 20 can respectively control the opening and closing of the first light source 31 and the second light source 32 to selectively treat the left eye and/or the or the right eye.

第四,在本实施例中,近红外光源30具有多个预设出光功率,即近红外光源30预设有多个不同的出光功率。控制器20可用于控制近红外光源30选择对应的预设出光功率,以使得该预设出光功率和被测用户的眼底疾病情况相适配。应理解,出光功率的选择,根据疾病对眼底造成的损伤程度及恢复情况来界定输出功率和疗效长度,可由医生根据临床经验决定,只要出光功率在安全范围内(<600mW/cm2)即可。Fourth, in this embodiment, the near-infrared light source 30 has a plurality of preset light output powers, that is, the near-infrared light source 30 is preset with a plurality of different light output powers. The controller 20 can be used to control the near-infrared light source 30 to select a corresponding preset light output power, so that the preset light output power is adapted to the fundus disease of the user under test. It should be understood that the choice of light output power, according to the degree of damage to the fundus caused by the disease and the recovery situation, to define the output power and the length of the curative effect, which can be determined by the doctor based on clinical experience, as long as the light output power is within the safe range (<600mW/cm2).

综上所述,本申请提供一种近红外光眼底治疗仪,该近红外光眼底治疗仪包括头戴式主体10和控制器20,头戴式主体10上设有与控制器20电连接的近红外光源30,近红外光源30用于照射被测用户的眼底,近红外光源30具有多个预设出光功率,控制器20用于控制近红外光源30选择对应的预设出光功率,以与被测用户的眼底疾病情况相适配。这样一来,本申请可根据被测用户的眼底疾病情况通过控制器20选择与被测用户的眼底疾病相适配的近红外光源30的预设出光功率,以控制近红外光源30发射对应出光功率的近红外光线,该近红外光线通过照射被测用户的眼球,透过眼球的屈光间质,将近红外光线的能量传入被测用户的眼底,针对眼底不同的目标组织发挥作用,以治疗与线粒体功能衰减有关的眼底疾病。本申请的近红外光眼底治疗仪,通过头戴式主体10可将近红外光眼底治疗仪佩戴于被测用户的头部,且通过选择与被测用户的眼底疾病情况相适配的预设出光功率,能够能方便、有效且针对性地辅助治疗眼中心性浆液性视网膜脉络膜病变、老年性黄斑变性等眼底疾病。To sum up, the present application provides a near-infrared light fundus therapeutic apparatus, the near-infrared light fundus therapeutic apparatus includes a head-mounted main body 10 and a controller 20 , and the head-mounted main body 10 is provided with a device that is electrically connected to the controller 20 . The near-infrared light source 30, the near-infrared light source 30 is used to illuminate the fundus of the user under test, the near-infrared light source 30 has a plurality of preset light output powers, and the controller 20 is used to control the near-infrared light source 30 to select the corresponding preset light output power, so as to match the preset light output power. It is suitable for the fundus disease of the tested user. In this way, the present application can select the preset light output power of the near-infrared light source 30 that is suitable for the fundus disease of the tested user through the controller 20 according to the fundus disease of the tested user, so as to control the near-infrared light source 30 to emit corresponding light output Power of near-infrared light, the near-infrared light irradiates the eyeball of the user under test, passes through the refractive interstitium of the eyeball, and the energy of the near-infrared light is transmitted to the fundus of the user under test, and plays a role in different target tissues of the fundus. Treatment of fundus diseases associated with diminished mitochondrial function. In the near-infrared light fundus therapy apparatus of the present application, the near-infrared light fundus therapy apparatus can be worn on the head of the tested user through the head-mounted main body 10, and a preset light output that is suitable for the fundus disease of the tested user is selected. It can conveniently, effectively and targetedly assist in the treatment of retinal diseases such as central serous retinal choroidopathy and age-related macular degeneration.

示例地,在本实施例中,近红外光源30可以为LED光源等可以发出近红外光线的任意一种光源。具体地,本领域技术人员可根据实际需求做出适当选择,在此不作限制。For example, in this embodiment, the near-infrared light source 30 may be any light source that can emit near-infrared light, such as an LED light source. Specifically, those skilled in the art can make appropriate selections according to actual needs, which are not limited here.

可选地,在本实施例中,近红外光源30的波长在760nm至850nm之间。近红外光源30的光功率密度在100mW/cm2至600mW/cm2之间。近红外光源30的发射功率以对应810nm波长为最高,近红外光源30可以采用单颗或多颗LED芯片,其中,左右两侧光源的单侧光功率密度控制在100mW/cm2至600mW/cm2之间。Optionally, in this embodiment, the wavelength of the near-infrared light source 30 is between 760 nm and 850 nm. The optical power density of the near-infrared light source 30 is between 100 mW/cm 2 and 600 mW/cm 2 . The emission power of the near-infrared light source 30 is the highest corresponding to the wavelength of 810 nm. The near-infrared light source 30 can use a single or multiple LED chips, and the single-side optical power density of the left and right light sources is controlled at 100mW/cm 2 to 600mW/cm between 2 .

另外,可选地,近红外光源30与被测用户的眼球角膜之间的距离在18mm至24mm之间。In addition, optionally, the distance between the near-infrared light source 30 and the cornea of the user's eyeball is between 18 mm and 24 mm.

由于LED光源发射的近红外光是较为散射的,为了使得近红外光源30发射的近红外光线控制在被测用户的对应眼部区域,以使大部分近红外光线入射到眼内,提高能量利用率,在本实施例中,近红外光眼底治疗仪还包括聚光筒40,聚光筒40设于头戴式主体10靠近近红外光源30处,用于对近红外光源30发射的近红外光进行汇聚。如此,近红外光线可以以散射的方式进入被测用户的眼底,以照射到被测用户的眼部所有部位进行近红外光治疗。Since the near-infrared light emitted by the LED light source is relatively scattered, in order to control the near-infrared light emitted by the near-infrared light source 30 to the corresponding eye area of the user under test, most of the near-infrared light is incident into the eye, thereby improving energy utilization. In this embodiment, the near-infrared light fundus therapy apparatus further includes a condensing tube 40, and the condensing tube 40 is arranged on the head-mounted main body 10 near the near-infrared light source 30, and is used for the near-infrared light emitted by the near-infrared light source 30. Light converges. In this way, the near-infrared light can enter the fundus of the user under test in a scattered manner, so as to irradiate all parts of the eye of the user under test for near-infrared light therapy.

为防止近红外光源30在工作过程中产生局部高温,在本实施例中,近红外光眼底治疗仪还包括散热装置50,散热装置50与控制器20电连接,用于对近红外光源30进行散热。In order to prevent the near-infrared light source 30 from generating local high temperature during the working process, in this embodiment, the near-infrared light fundus therapy apparatus further includes a heat dissipation device 50, and the heat dissipation device 50 is electrically connected to the controller 20, and is used for the operation of the near-infrared light source 30. heat dissipation.

具体地,在本实施例中,散热装置50可对应装设于近红外光源30的电路板的一侧。示例地,本实施例的散热装置50可通过风扇进行散热或者通过水冷的方式进行散热,在此不作限制。另外,当左右眼采用相互独立的光源时,每个光源可以分别配有独立的散热装置50。需要说明的是,在使用的过程中,当功率过大时,可通过控制器20启动散热装置50进行散热冷却。对应地,当左右眼采用相互独立的光源时,可根据左右眼的设置功率情况选择启动用于对应的散热装置50。Specifically, in this embodiment, the heat dissipation device 50 can be correspondingly installed on one side of the circuit board of the near-infrared light source 30 . For example, the heat dissipation device 50 in this embodiment may dissipate heat through a fan or through water cooling, which is not limited herein. In addition, when independent light sources are used for the left and right eyes, each light source may be provided with an independent heat dissipation device 50 respectively. It should be noted that, in the process of use, when the power is too large, the controller 20 can activate the heat dissipation device 50 to conduct heat dissipation and cooling. Correspondingly, when independent light sources are used for the left and right eyes, the corresponding heat sink 50 can be selected to be activated according to the power settings of the left and right eyes.

在本实施例中,近红外光眼底治疗仪还包括与控制器20电连接的定时器70,控制器20用于根据接收到的定时器70的定时信息控制控制器20与近红外光源30之间的连接电路断开。In this embodiment, the near-infrared light fundus therapy apparatus further includes a timer 70 electrically connected to the controller 20 , and the controller 20 is configured to control the distance between the controller 20 and the near-infrared light source 30 according to the received timing information of the timer 70 . The connection circuit between them is broken.

即,用户可根据病情情况自定义设置对应的治疗时长,通过定时器70记录近红外光眼底治疗仪的运行时间,控制器20根据定时信息控制近红外光源30和控制器20之间的连接电路断开(即当定时时间到时,控制器20控制近红外光源30和控制器20之间的连接电路断开),从而使得近红外光源30切断,停止出射近红外光线,设备停止运行。That is, the user can customize the corresponding treatment duration according to the condition, record the running time of the near-infrared light fundus therapy apparatus through the timer 70, and the controller 20 controls the connection circuit between the near-infrared light source 30 and the controller 20 according to the timing information Disconnection (that is, when the timer expires, the controller 20 controls the connection circuit between the near-infrared light source 30 and the controller 20 to disconnect), so that the near-infrared light source 30 is cut off, stops emitting near-infrared light, and the device stops running.

需要说明的是,第一,本实施例提供的显示装置60上还可以对应设有定时调节按键,用户可根据定时调节按键自定义调节定时器70的定时时长。It should be noted that, first, the display device 60 provided in this embodiment may also be provided with corresponding timing adjustment buttons, and the user can customize the timing duration of the timer 70 according to the timing adjustment buttons.

第二,当左右眼采用相互独立的光源时,定时调节按钮也可以对应左右眼各设置一组,以便于两个光源的分别调节。Second, when the left and right eyes use independent light sources, one set of timing adjustment buttons can also be provided for each of the left and right eyes, so as to facilitate the adjustment of the two light sources respectively.

可选地,在本实施例中,近红外光眼底治疗仪还包括显示装置60,显示装置60与控制器20电连接,用于显示近红外光源30的出光功率和定时器70的定时时间。Optionally, in this embodiment, the near-infrared light fundus therapy apparatus further includes a display device 60 that is electrically connected to the controller 20 for displaying the light output power of the near-infrared light source 30 and the timing of the timer 70 .

需要说明的是,第一,示例地,该显示装置60可以安装于头戴式主体10上,也可以通过导线和头戴式主体10连接。优选地,在本实施例中,该显示装置60通过导线和头戴式主体10连接。如此,用户可通过显示装置60直观地读取近红外光线的出光功率和定时时间。It should be noted that, first, for example, the display device 60 may be installed on the head-mounted body 10, or may be connected to the head-mounted body 10 through wires. Preferably, in this embodiment, the display device 60 is connected to the head-mounted body 10 through wires. In this way, the user can intuitively read the output power and timing of the near-infrared light through the display device 60 .

第二,本实施例提供的显示装置60上还对应设有功率调节按键,用户可根据功率调节按键自定义调节近红外光源30的出光功率。例如,通过功率调节按键的上下调节按键增加或减少功率(例如每5mw或者10mw为一个功率段)。需要说明的是,当左右眼采用相互独立的光源时,功率调节按键也可以对应左右眼各设置一组,以便于两个光源的分别调节。Second, the display device 60 provided in this embodiment is also provided with a corresponding power adjustment button, and the user can customize the output power of the near-infrared light source 30 according to the power adjustment button. For example, the power is increased or decreased through the up and down adjustment buttons of the power adjustment button (for example, every 5mw or 10mw is a power segment). It should be noted that when independent light sources are used for the left and right eyes, a set of power adjustment buttons may also be provided for each of the left and right eyes, so as to facilitate the adjustment of the two light sources respectively.

在本实施例中,近红外光眼底治疗仪还包括分别与控制器20电连接的用于紧急断电的紧急断电装置80。紧急断电装置80与控制器20电连接,控制器20用于根据接收到的紧急断电装置80的断电信息控制控制器20与近红外光源30之间的连接电路断开。需要说明的是,当左右眼采用相互独立的光源时,紧急断电装置80可以同时断开左眼和右眼的近红外光源30的电源,以便于在紧急情况下,停止两个光源的能量输出。In this embodiment, the near-infrared light fundus therapy apparatus further includes emergency power-off devices 80 electrically connected to the controller 20 for emergency power-off. The emergency power-off device 80 is electrically connected to the controller 20 , and the controller 20 is configured to control the disconnection of the connection circuit between the controller 20 and the near-infrared light source 30 according to the received power-off information of the emergency power-off device 80 . It should be noted that when the left and right eyes use independent light sources, the emergency power-off device 80 can simultaneously disconnect the power of the near-infrared light sources 30 for the left and right eyes, so as to stop the energy of the two light sources in an emergency output.

除此之外,本实施例中,显示装置60和头盔主体上还分别设有与控制器20电连接的运行指示灯90,当设备运行时,运行指示灯90亮。具体地,当左右眼采用相互独立的光源时,显示装置60上对应左眼和对应右眼的位置分别设置有一个运行指示灯90。In addition, in this embodiment, the display device 60 and the helmet body are respectively provided with a running indicator light 90 electrically connected to the controller 20. When the device is running, the running indicator light 90 is on. Specifically, when independent light sources are used for the left and right eyes, a running indicator light 90 is respectively provided on the display device 60 at positions corresponding to the left eye and corresponding to the right eye.

以上所述仅为本发明的可选实施例而已,并不用于限制本发明,对于本领域的技术人员来说,本发明可以有各种更改和变化。凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。The above descriptions are only optional embodiments of the present invention, and are not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims (11)

1. The utility model provides a near-infrared light eye ground therapeutic instrument, its characterized in that, includes wear-type main part and controller, be equipped with in the wear-type main part with the near-infrared light source that the controller electricity is connected, near-infrared light source is used for shining surveyed user's eye ground, near-infrared light source has a plurality of light output power of predetermineeing, the controller is used for control near-infrared light source selects to correspond predetermine light output power, with surveyed user's eye ground disease condition looks adaptation.
2. The near-infrared fundus treatment apparatus of claim 1, wherein the near-infrared light source is an LED light source.
3. The near-infrared fundus treatment apparatus according to claim 1, wherein the wavelength of said near-infrared light source is between 760nm and 850 nm.
4. The near-infrared fundus treatment apparatus of claim 1, wherein the optical power density of said near-infrared light source is 100mW/cm2To 600mW/cm2In the meantime.
5. The near-infrared fundus treatment apparatus of claim 1, wherein the distance between said near-infrared light source and the cornea of the eye of said user to be tested is between 18mm and 24 mm.
6. The near-infrared fundus treatment apparatus according to claim 1, further comprising a light-gathering tube disposed on the head-mounted main body near the near-infrared light source for gathering the near-infrared light emitted from the near-infrared light source.
7. The near-infrared fundus treatment apparatus according to claim 1, wherein said near-infrared light source comprises a first light source and a second light source arranged in parallel, said first light source and said second light source respectively illuminate the left eye and the right eye of said user to be measured, and said first light source and said second light source are respectively electrically connected to said controller.
8. The near-infrared fundus treatment apparatus according to claim 1 or 7, further comprising a heat sink electrically connected to the controller for dissipating heat from the near-infrared light source.
9. The near-infrared light fundus treatment apparatus according to claim 1, further comprising a timer electrically connected to said controller, said controller being configured to control a disconnection of a connection circuit between said controller and said near-infrared light source according to received timing information of said timer.
10. The near-infrared light fundus treatment apparatus according to claim 9, further comprising a display device electrically connected to said controller for displaying the output power of said near-infrared light source and the timing time of said timer.
11. The near-infrared fundus treatment apparatus according to claim 1, further comprising an emergency power-off device electrically connected to said controller, said controller being configured to control a connection circuit between said controller and said near-infrared light source to be disconnected according to a power-off information received from said emergency power-off device.
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