CN116559167A - Photographing recognition coagulation sample abnormality early warning judging method and detecting device thereof - Google Patents
Photographing recognition coagulation sample abnormality early warning judging method and detecting device thereof Download PDFInfo
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Abstract
本发明提供了一种拍照识别凝血样本异常预警判断方法及其检测装置，涉及医疗诊断的技术领域。拍照识别凝血样本异常预警判断方法包括以下步骤：采用血凝管进行采血，并对血凝管进行离心处理；利用摄像机对血凝管进行拍摄，并利用图像识别功能判断血凝管内血浆层和血细胞层的高度；对血细胞层的高度与血浆总高度进行对比，比值大于0.55时进行报警。检测装置包括检测平台、摄像机、血凝管支架、处理器和报警器；摄像机和血凝管支架均设置在检测平台上；摄像机和报警器均与处理器电连接。达到了缓解凝血时间的假性延长的技术效果。
The invention provides a pre-warning and judging method and a detection device for abnormality of coagulation samples by taking pictures and identifying them, and relates to the technical field of medical diagnosis. The method for early warning and judging of abnormal coagulation samples by taking pictures includes the following steps: collecting blood by using a blood coagulation tube, and centrifuging the blood coagulation tube; using a camera to shoot the blood coagulation tube, and using the image recognition function to judge the plasma layer and blood cells in the blood coagulation tube The height of the layer; the height of the blood cell layer is compared with the total height of the plasma, and an alarm is given when the ratio is greater than 0.55. The detection device includes a detection platform, a camera, a blood coagulation tube support, a processor and an alarm; both the camera and the blood coagulation tube support are arranged on the detection platform; the camera and the alarm are both electrically connected to the processor. The technical effect of alleviating the false prolongation of coagulation time is achieved.
Description
技术领域technical field
本发明涉及医疗诊断技术领域，具体而言，涉及拍照识别凝血样本异常预警判断方法及其检测装置。The invention relates to the technical field of medical diagnosis, in particular to a method for early warning and judging abnormality of blood coagulation samples by taking photos and a detection device thereof.
背景技术Background technique
在临床日常工作中，凝血实验用于出血性疾病的筛选与诊断、血栓前状态的检查、弥漫性血管内凝血出血疾病(DIC)的实验诊断、及抗凝治疗者的用药指导和预后估计等，凝血检验至关重要。常规凝血检测采用商品化的枸橼酸钠抗凝真空采血管采血。In daily clinical work, coagulation tests are used for screening and diagnosis of bleeding disorders, examination of pre-thrombotic state, experimental diagnosis of disseminated intravascular coagulation bleeding disease (DIC), medication guidance and prognosis estimation for anticoagulants , blood coagulation test is very important. For routine coagulation testing, commercial sodium citrate anticoagulant vacuum blood collection tubes were used for blood collection.
一般情况下，凝血时间延长代表患者有出血风险，特别对于手术患者，需谨慎安排手术。但是在临床工作中，少数患者因血细胞比容(hematocrit，HCT；packed cell volume，PCV)过高，在采用商品化的枸橼酸钠抗凝真空采血管采血后常规进行凝血检测，会造成凝血时间的假性延长。由于HCT检测属于血常规检测项目，需要使用血细胞分析仪进行检测且血常规检测样本类型(临床使用EDTA抗凝真空采血管采血)与凝血检测样本类型(临床使用枸橼酸钠抗凝的真空采血管采血)不同，而目前市面上所有凝血检测项目所使用的凝血分析仪不具备HCT检测功能，因此临床很难发现HCT异常高值导致的凝血时间假性延长，会进一步延误医生判断和患者治疗。In general, prolonged coagulation time means that the patient has a risk of bleeding, especially for surgical patients, surgery should be arranged carefully. However, in clinical work, due to high hematocrit (hematocrit, HCT; packed cell volume, PCV), a small number of patients routinely perform coagulation testing after blood collection in commercial sodium citrate anticoagulant vacuum blood collection tubes, which will cause coagulation Pseudo-prolongation of time. Since HCT detection is a routine blood test item, it is necessary to use a hematology analyzer for detection, and the sample type of blood routine test (clinical use of EDTA anticoagulated vacuum blood collection tubes) and coagulation test sample type (clinical use of sodium citrate anticoagulated vacuum blood collection tubes) However, the coagulation analyzers currently used in all coagulation testing items on the market do not have the HCT detection function, so it is difficult to find the false prolongation of the coagulation time caused by the abnormally high value of HCT, which will further delay the doctor's judgment and the patient's treatment .
发明内容Contents of the invention
本发明的目的在于提供一种拍照识别凝血样本异常预警判断方法及其检测装置，以缓解现有技术中凝血时间的假性延长的技术问题。The purpose of the present invention is to provide a pre-warning and judging method and detection device for taking pictures to identify abnormality of coagulation samples, so as to alleviate the technical problem of false prolongation of coagulation time in the prior art.
第一方面，本发明实施例提供了一种拍照识别凝血样本异常预警判断方法，包括以下步骤：In the first aspect, an embodiment of the present invention provides a method for early warning and judging abnormality of blood coagulation samples by taking pictures, including the following steps:
采用血凝管进行采血，并对血凝管进行离心处理；Use blood coagulation tubes for blood collection, and centrifuge the blood coagulation tubes;
利用摄像机对血凝管进行拍摄，并利用图像识别功能判断血凝管内血浆层和血细胞层的高度；Use the camera to shoot the blood coagulation tube, and use the image recognition function to judge the height of the plasma layer and blood cell layer in the blood coagulation tube;
对血细胞层的高度与血浆总高度进行对比，比值大于0.55时进行报警。The height of the blood cell layer is compared with the total height of the plasma, and an alarm is given when the ratio is greater than 0.55.
结合第一方面，本发明实施例提供了第一方面的一种可能的实施方式，其中，上述摄像机与待拍摄血凝管处于同一水平面。With reference to the first aspect, the embodiment of the present invention provides a possible implementation manner of the first aspect, wherein the above-mentioned camera is at the same level as the blood coagulation vessel to be photographed.
结合第一方面，本发明实施例提供了第一方面的一种可能的实施方式，其中，上述离心处理的离心力在1500－2500g之间。In combination with the first aspect, the embodiment of the present invention provides a possible implementation manner of the first aspect, wherein the centrifugal force of the above-mentioned centrifugation treatment is between 1500-2500 g.
结合第一方面，本发明实施例提供了第一方面的一种可能的实施方式，其中，上述离心处理的离心力为1500g。With reference to the first aspect, the embodiment of the present invention provides a possible implementation manner of the first aspect, wherein the centrifugal force of the above-mentioned centrifugation treatment is 1500 g.
结合第一方面，本发明实施例提供了第一方面的一种可能的实施方式，其中，上述离心处理的离心时间在8－18min之间。In combination with the first aspect, the embodiment of the present invention provides a possible implementation of the first aspect, wherein the centrifugation time of the above-mentioned centrifugation treatment is between 8-18 minutes.
结合第一方面，本发明实施例提供了第一方面的一种可能的实施方式，其中，上述离心处理的离心时间在10－16min之间。In combination with the first aspect, the embodiment of the present invention provides a possible implementation of the first aspect, wherein the centrifugation time of the above centrifugation treatment is between 10-16 minutes.
结合第一方面，本发明实施例提供了第一方面的一种可能的实施方式，其中，上述离心处理的离心时间位15min。With reference to the first aspect, the embodiment of the present invention provides a possible implementation manner of the first aspect, wherein the centrifugation time of the centrifugation treatment is 15 minutes.
结合第一方面，本发明实施例提供了第一方面的一种可能的实施方式，其中，上述血凝管采用枸橼酸钠抗凝真空采血管。With reference to the first aspect, the embodiment of the present invention provides a possible implementation of the first aspect, wherein the blood coagulation tube is a sodium citrate anticoagulated vacuum blood collection tube.
第二方面，本发明实施例提供了一种检测装置，包括检测平台、摄像机、血凝管支架、处理器和报警器；In the second aspect, an embodiment of the present invention provides a detection device, including a detection platform, a camera, a blood coagulation tube support, a processor, and an alarm;
所述摄像机和所述血凝管支架均设置在所述检测平台上；Both the camera and the blood coagulation tube support are set on the detection platform;
所述摄像机和所述报警器均与所述处理器电连接。Both the camera and the alarm are electrically connected to the processor.
结合第一方面，本发明实施例提供了第二方面的一种可能的实施方式，其中，上述高度标识位于所述血凝管支架后方。With reference to the first aspect, the embodiment of the present invention provides a possible implementation manner of the second aspect, wherein the height mark is located behind the blood coagulation vessel stent.
有益效果：Beneficial effect:
本发明提供了一种拍照识别凝血样本异常预警判断方法，包括以下步骤：采用血凝管进行采血，并对血凝管进行离心处理；利用摄像机对血凝管进行拍摄，并利用图像识别功能判断血凝管内血浆层和血细胞层的高度；对血细胞层的高度与血浆总高度进行对比，比值大于0.55时进行报警。The invention provides a method for pre-warning and judging the abnormality of blood coagulation samples by photographing, comprising the following steps: using a blood coagulation tube to collect blood, and centrifuging the blood coagulation tube; using a camera to shoot the blood coagulation tube, and using the image recognition function to judge The height of the plasma layer and blood cell layer in the blood coagulation tube; compare the height of the blood cell layer with the total plasma height, and alarm when the ratio is greater than 0.55.
具体的，在进行凝血测试时，医务人员使用血凝管进行采血，然后对血凝管进行离心处理，使得血凝管内的血细胞与血浆分离，然后利用摄像机对血凝管进行拍照，利用图像识别功能提取血凝管内血细胞层与血浆层的高度，然后通过计算血细胞层的高度与血浆总高度的比值，比值大于0.55时表明采用商品化的血凝管进行凝血测试的假性延长风险，并进行报警。Specifically, when performing a blood coagulation test, medical personnel use a blood coagulation tube to collect blood, and then centrifuge the blood coagulation tube to separate the blood cells and plasma in the blood coagulation tube, then use a camera to take pictures of the blood coagulation tube, and use image recognition The function extracts the height of the blood cell layer and the plasma layer in the blood coagulation tube, and then calculates the ratio of the height of the blood cell layer to the total height of the plasma. When the ratio is greater than 0.55, it indicates the risk of false prolongation of the coagulation test using a commercial blood coagulation tube, and carries out Call the police.
本发明提供了一种检测装置，包括检测平台、摄像机、血凝管支架、处理器和报警器；摄像机和血凝管支架均设置在检测平台上；摄像机和报警器均与处理器电连接。检测装置与现有技术相比具有上述的优势，此处不再赘述。The invention provides a detection device, which includes a detection platform, a camera, a blood coagulation tube support, a processor and an alarm; the camera and the blood coagulation tube support are both arranged on the detection platform; the camera and the alarm are both electrically connected to the processor. Compared with the prior art, the detection device has the above-mentioned advantages, which will not be repeated here.
附图说明Description of drawings
为了更清楚地说明本发明具体实施方式或现有技术中的技术方案，下面将对具体实施方式或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图是本发明的一些实施方式，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。In order to more clearly illustrate the specific implementation of the present invention or the technical solutions in the prior art, the following will briefly introduce the accompanying drawings that need to be used in the specific implementation or description of the prior art. Obviously, the accompanying drawings in the following description The drawings show some implementations of the present invention, and those skilled in the art can obtain other drawings based on these drawings without any creative effort.
图1为本发明实施例提供的检测装置的示意图。Fig. 1 is a schematic diagram of a detection device provided by an embodiment of the present invention.
图标：icon:
100－检测平台；100 - detection platform;
200－摄像机；200 - video camera;
300－血凝管支架；300 - blood coagulation tube stent;
400－高度标识。400 - height identification.
具体实施方式Detailed ways
下面将结合附图对本发明的技术方案进行清楚、完整地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。The technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are part of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
在本发明的描述中，需要理解的是，术语“中心”、“纵向”、“横向”、“长度”、“宽度”、“厚度”、“上”、“下”、“前”、“后”、“左”、“右”、“竖直”、“水平”、“顶”、“底”、“内”、“外”、“顺时针”、“逆时针”、“轴向”、“径向”、“周向”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。In describing the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", " Back", "Left", "Right", "Vertical", "Horizontal", "Top", "Bottom", "Inner", "Outer", "Clockwise", "Counterclockwise", "Axial" , "radial", "circumferential" and other indicated orientations or positional relationships are based on the orientations or positional relationships shown in the drawings, which are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying the referred device or Elements must have certain orientations, be constructed and operate in certain orientations, and therefore should not be construed as limitations on the invention.
此外，术语“第一”、“第二”仅用于描述目的，而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此，限定有“第一”、“第二”的特征可以明示或者隐含地包括一个或者更多个该特征。在本发明的描述中，“多个”的含义是两个或两个以上，除非另有明确具体的限定。In addition, the terms "first" and "second" are used for descriptive purposes only, and cannot be interpreted as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features. Thus, a feature defined as "first" and "second" may explicitly or implicitly include one or more of these features. In the description of the present invention, "plurality" means two or more, unless otherwise specifically defined.
在本发明中，除非另有明确的规定和限定，术语“安装”、“相连”、“连接”、“固定”等术语应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或成一体；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间接相连，可以是两个元件内部的连通或两个元件的相互作用关系。对于本领域的普通技术人员而言，可以根据具体情况理解上述术语在本发明中的具体含义。In the present invention, unless otherwise clearly specified and limited, terms such as "installation", "connection", "connection" and "fixation" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection , or integrated; it can be mechanically connected or electrically connected; it can be directly connected or indirectly connected through an intermediary, and it can be the internal communication of two components or the interaction relationship between two components. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present invention according to specific situations.
下面通过具体的实施例并结合附图对本发明做进一步的详细描述。The present invention will be described in further detail below through specific embodiments and in conjunction with the accompanying drawings.
本实施例提供了一种拍照识别凝血样本异常预警判断方法，包括以下步骤：采用血凝管进行采血，并对血凝管进行离心处理；利用摄像机对血凝管进行拍摄，并利用图像识别功能判断血凝管内血浆层和血细胞层的高度；对血细胞层的高度与血浆总高度进行对比，比值大于0.55时进行报警。This embodiment provides a method for pre-warning and judging the abnormality of blood coagulation samples by taking pictures, including the following steps: using a blood coagulation tube to collect blood, and centrifuging the blood coagulation tube; using a camera to shoot the blood coagulation tube, and using the image recognition function Judge the height of the plasma layer and blood cell layer in the blood coagulation tube; compare the height of the blood cell layer with the total plasma height, and give an alarm when the ratio is greater than 0.55.
具体的，在进行凝血测试时，医务人员使用血凝管进行采血，然后对血凝管进行离心处理，使得血凝管内的血细胞与血浆分离，然后利用摄像机对血凝管进行拍照，利用图像识别功能提取血凝管内血细胞层与血浆层的高度，然后通过计算血细胞层的高度与血浆总高度的比值，比值大于0.55时表明采用商品化的血凝管进行凝血测试的假性延长风险，并进行报警。Specifically, when performing a blood coagulation test, medical personnel use a blood coagulation tube to collect blood, and then centrifuge the blood coagulation tube to separate the blood cells and plasma in the blood coagulation tube, then use a camera to take pictures of the blood coagulation tube, and use image recognition The function extracts the height of the blood cell layer and the plasma layer in the blood coagulation tube, and then calculates the ratio of the height of the blood cell layer to the total height of the plasma. When the ratio is greater than 0.55, it indicates the risk of false prolongation of the coagulation test using a commercial blood coagulation tube, and carries out Call the police.
其中，血浆总高度指的是血凝管内液面整体的高度，此高度包括血细胞层的高度和血浆层的高度。Wherein, the total plasma height refers to the overall height of the liquid level in the blood coagulation tube, which includes the height of the blood cell layer and the height of the plasma layer.
其中，血凝管采用枸橼酸钠抗凝真空采血管。Among them, the blood coagulation tube adopts sodium citrate anticoagulation vacuum blood collection tube.
其中，通过拍照成像和图像识别原理检测离心后放入凝血分析仪器进行样本检测的凝血样本整个液面高度，以及细胞层(或血浆层)高度，计算出凝血分析样本估算HCT值(＝细胞层高度/凝血样本整个液面高度)。依据该原理人工模拟仪器拍照成像和图像识别分析得到临床凝血分析样本研究数据，通过测量离心后凝血分析样本细胞层高度与整个样本高度占比估算出的凝血分析样本估算HCT值(x)与血细胞分析仪HCT实测值(y)间呈现出较好的线性关系(y＝1.0204x－0.0135，R2＝0.9519)，因此可依据此原理估算HCT值及设计相应的软件使凝血分析仪具备凝血分析样本异常预警判断功能。Among them, the whole liquid level of the coagulation sample and the height of the cell layer (or plasma layer) are detected by the principle of photographing, imaging and image recognition after being centrifuged into the coagulation analysis instrument for sample detection, and the estimated HCT value (= cell layer) of the coagulation analysis sample is calculated. height/height of the entire liquid level of the clotted sample). According to this principle, the research data of clinical coagulation analysis samples are obtained by artificially simulating the instrument to take pictures and image and image recognition analysis. By measuring the ratio of the cell layer height of the coagulation analysis sample after centrifugation to the height of the whole sample, the estimated HCT value (x) of the coagulation analysis sample and the blood cell The HCT measured value (y) of the analyzer shows a good linear relationship (y=1.0204x-0.0135, R 2 =0.9519), so the HCT value can be estimated based on this principle and the corresponding software can be designed to make the coagulation analyzer capable of coagulation analysis Sample abnormal early warning and judgment function.
本实施例的可选方案中，摄像机与待拍摄血凝管处于同一水平面。In an optional solution of this embodiment, the camera is at the same level as the blood coagulation tube to be photographed.
具体的，摄像机在拍摄血凝管时，摄像机与血凝管处于同一水平面。Specifically, when the camera shoots the blood coagulation tube, the camera and the blood coagulation tube are at the same level.
本实施例的可选方案中，离心处理的离心力在1500－2500g之间。In an optional solution of this embodiment, the centrifugal force of the centrifugal treatment is between 1500-2500g.
具体的，离心处理的离心力可以设置为1500g，或者，离心处理的离心力可以设置为1600g，或者，离心处理的离心力可以设置为1700g，或者，离心处理的离心力可以设置为1800g，或者，离心处理的离心力可以设置为1900g，或者，离心处理的离心力可以设置为2000g，或者，离心处理的离心力可以设置为2100g，或者，离心处理的离心力可以设置为2200g，或者，离心处理的离心力可以设置为2300g，或者，离心处理的离心力可以设置为2400g，或者，离心处理的离心力可以设置为2200g。Specifically, the centrifugal force of centrifugal treatment can be set to 1500g, or, the centrifugal force of centrifugal treatment can be set to 1600g, or, the centrifugal force of centrifugal treatment can be set to 1700g, or, the centrifugal force of centrifugal treatment can be set to 1800g, or, the centrifugal force of centrifugal treatment can be set to 1800g, or, The centrifugal force can be set to 1900g, or the centrifugal force can be set to 2000g, or the centrifugal force can be set to 2100g, or the centrifugal force can be set to 2200g, or the centrifugal force can be set to 2300g, Alternatively, the centrifugal force of the centrifugal treatment may be set to 2400g, or, the centrifugal force of the centrifugal treatment may be set to 2200g.
本实施例的可选方案中，离心处理的离心时间在8－18min之间。In an alternative solution of this embodiment, the centrifugation time of the centrifugation treatment is between 8-18 minutes.
具体的，离心处理的离心时间为8min，或者，离心处理的离心时间为9min，或者，离心处理的离心时间为10min，或者，离心处理的离心时间为11min，或者，离心处理的离心时间为12min，或者，离心处理的离心时间为13min，或者，离心处理的离心时间为14min，或者，离心处理的离心时间为15min，或者，离心处理的离心时间为16min，或者，离心处理的离心时间为17min，或者，离心处理的离心时间为18min。Specifically, the centrifugation time of the centrifugation treatment is 8 minutes, or the centrifugation time of the centrifugation treatment is 9 minutes, or the centrifugation time of the centrifugation treatment is 10 minutes, or the centrifugation time of the centrifugation treatment is 11 minutes, or the centrifugation time of the centrifugation treatment is 12 minutes , or, the centrifugation time for centrifugation is 13min, or, the centrifugation time for centrifugation is 14min, or, the centrifugation time for centrifugation is 15min, or, the centrifugation time for centrifugation is 16min, or, the centrifugation time for centrifugation is 17min , or, the centrifugation time of centrifugation is 18min.
其中，离心处理的离心力可以设置为1500g，离心时间设置为15min。Wherein, the centrifugal force of the centrifugation treatment can be set to 1500 g, and the centrifugation time can be set to 15 minutes.
或者，离心处理的离心力可以设置为2500g，离心时间设置为10min。Or, the centrifugal force of the centrifugation can be set to 2500g, and the centrifugation time can be set to 10min.
参加图1所示，本实施例提供了一种检测装置，包括检测平台100、摄像机200、血凝管支架300、处理器和报警器；摄像机200和血凝管支架300均设置在检测平台100上；摄像机200和报警器均与处理器电连接。As shown in Figure 1, the present embodiment provides a detection device, including a detection platform 100, a camera 200, a blood coagulation tube support 300, a processor and an alarm; the camera 200 and the blood coagulation tube support 300 are all arranged on the detection platform 100 Above; the camera 200 and the alarm are both electrically connected to the processor.
其中，检测平台100呈L型或者U型。Wherein, the detection platform 100 is L-shaped or U-shaped.
其中，高度标识400位于血凝管支架300后方的检测平台100上。Wherein, the height mark 400 is located on the detection platform 100 behind the blood coagulation tube support 300 .
最后应说明的是：以上实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述实施例所记载的技术方案进行修改，或者对其中部分或者全部技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明实施例技术方案的范围。Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: it can still be Modifications are made to the technical solutions described in the foregoing embodiments, or equivalent replacements are made to some or all of the technical features; these modifications or replacements do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
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