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CL2016000333A1 - Proteínas de unión a il-1 - Google Patents

Proteínas de unión a il-1

Info

Publication number
CL2016000333A1
CL2016000333A1 CL2016000333A CL2016000333A CL2016000333A1 CL 2016000333 A1 CL2016000333 A1 CL 2016000333A1 CL 2016000333 A CL2016000333 A CL 2016000333A CL 2016000333 A CL2016000333 A CL 2016000333A CL 2016000333 A1 CL2016000333 A1 CL 2016000333A1
Authority
CL
Chile
Prior art keywords
binding proteins
humana
conjugado
1alfa
codifies
Prior art date
Application number
CL2016000333A
Other languages
English (en)
Inventor
Chengbin Wu
Chung-Ming Hsieh
Diminic J Ambrosi
Tariq Chayur
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of CL2016000333A1 publication Critical patent/CL2016000333A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6875Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin
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Abstract

PROTEÍNAS DE UNIÓN QUE SE UNEN A IL-1beta HUMANA Y A IL-1alfa HUMANA; CONJUGADO QUE LA COMPRENDE; COMPOSICIÓN FARMACÉUTICA; ÁCIDO NUCLEICO QUE LA CODIFICA; VECTOR; CÉLULA HUÉSPED; MÉTODO DE PRODUCCIÓN; Y USO EN UN TRASTORNO EN EL CUAL LA ACTIVIDAD DE LA IL-1 ES PERJUDICIAL (DIVISIONAL DE SOL. N°3187-12).
CL2016000333A 2010-05-14 2016-02-11 Proteínas de unión a il-1 CL2016000333A1 (es)

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US201061425701P 2010-12-21 2010-12-21

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CL2012003187A CL2012003187A1 (es) 2010-05-14 2012-11-14 Proteinas de union a il-1 beta humana y ala il-1 alfa humana; conjugado de dicha proteina de unión; composicion para la liberacion de una proteina de unión; composicion farmaceutica.
CL2016000333A CL2016000333A1 (es) 2010-05-14 2016-02-11 Proteínas de unión a il-1

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