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CL2008003066A1 - Compuestos derivados de 1-[3-(fenilamino)-5-(piridin-4-il)-1h-1,2,4-triazol-1-il]-alquil-2-ol; composición farmacéutica; procedimiento de preparación de dicha composición; y uso para el tratamiento o prevención de una enfermedad del sistema nervioso central. - Google Patents

Compuestos derivados de 1-[3-(fenilamino)-5-(piridin-4-il)-1h-1,2,4-triazol-1-il]-alquil-2-ol; composición farmacéutica; procedimiento de preparación de dicha composición; y uso para el tratamiento o prevención de una enfermedad del sistema nervioso central.

Info

Publication number
CL2008003066A1
CL2008003066A1 CL2008003066A CL2008003066A CL2008003066A1 CL 2008003066 A1 CL2008003066 A1 CL 2008003066A1 CL 2008003066 A CL2008003066 A CL 2008003066A CL 2008003066 A CL2008003066 A CL 2008003066A CL 2008003066 A1 CL2008003066 A1 CL 2008003066A1
Authority
CL
Chile
Prior art keywords
composition
disease
prevention
preparing
treatment
Prior art date
Application number
CL2008003066A
Other languages
English (en)
Inventor
Johannes Wilhelmus John F Thuring
Theodorus Dinklo
Anne Simone Josephine Lesage
Bruyn Marcel Frans Leopold De
Wei Zhuang
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CL2008003066A1 publication Critical patent/CL2008003066A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPUESTO DE FORMULA (I), DONDE R1, R2, R3, R4, R5 Y R6 SON COMO SE DEFINEN EN LA MEMORIA DESCRIPTIVA. USO DE DICHO COMPUESTO QUE SIRVE PARA PREPARAR UN MEDICAMENTO UTIL PARA EL TRATAMIENTO O PREVENCION DE UNA ENFERMEDAD O AFECCION SELECCIONADA ENTRE TRASTORNOS PSICOTICOS, ENFERMEDADES O TRASTORNOS ASOCIADOS CON DETERIORO INTELECTUAL, ENFERMEDADES O AFECCIONES  INFLAMATORIAS EN LAS CUALES LA MODULACION DEL RECEPTOR A7 NICOTINICO ES BENEFICIOSA. COMPOSICION FARMACEUTICA QUE COMPRENDE UN PORTADOR FARMACEUTICAMENTE ACEPTABLE Y COMO INGREDIENTE ACTIVO UNA CANTIDAD TERAPEUTICAMENTE EFICAZ DE DICHO COMPUESTO. PROCEDIMIENTO PARA PREPARAR DICHA COMPOSICION.
CL2008003066A 2007-10-18 2008-10-16 Compuestos derivados de 1-[3-(fenilamino)-5-(piridin-4-il)-1h-1,2,4-triazol-1-il]-alquil-2-ol; composición farmacéutica; procedimiento de preparación de dicha composición; y uso para el tratamiento o prevención de una enfermedad del sistema nervioso central. CL2008003066A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07118825 2007-10-18

Publications (1)

Publication Number Publication Date
CL2008003066A1 true CL2008003066A1 (es) 2009-10-16

Family

ID=38754647

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008003066A CL2008003066A1 (es) 2007-10-18 2008-10-16 Compuestos derivados de 1-[3-(fenilamino)-5-(piridin-4-il)-1h-1,2,4-triazol-1-il]-alquil-2-ol; composición farmacéutica; procedimiento de preparación de dicha composición; y uso para el tratamiento o prevención de una enfermedad del sistema nervioso central.

Country Status (16)

Country Link
US (1) US8440701B2 (es)
EP (1) EP2212309B1 (es)
JP (1) JP2011500625A (es)
CN (1) CN101827836B (es)
AR (1) AR070661A1 (es)
AU (1) AU2008313776B2 (es)
CA (1) CA2697974C (es)
CL (1) CL2008003066A1 (es)
ES (1) ES2424023T3 (es)
IL (1) IL205101A (es)
MX (1) MX2010004177A (es)
PA (1) PA8799801A1 (es)
PE (1) PE20090877A1 (es)
RU (1) RU2474579C2 (es)
TW (1) TWI438198B (es)
WO (1) WO2009050186A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA97257C2 (en) * 2006-10-19 2012-01-25 Такеда Фармасьютикал Компани Лимитед Indole derivatives
JO2784B1 (en) * 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
CA2714662C (en) * 2008-03-19 2016-05-10 Janssen Pharmaceutica Nv Trisubstituted 1,2,4-triazoles as nicotinic acetylcholine receptor modulators
EA018187B1 (ru) * 2008-05-09 2013-06-28 Янссен Фармацевтика Нв Тризамещенные пиразолы в качестве модуляторов рецепторов ацетилхолина
MY161236A (en) 2011-02-25 2017-04-14 Janssen Pharmaceutica Nv (pyridin-4-yl)benzylamides as allosteric modulators of alpha 7 nachr

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MY161236A (en) 2011-02-25 2017-04-14 Janssen Pharmaceutica Nv (pyridin-4-yl)benzylamides as allosteric modulators of alpha 7 nachr

Also Published As

Publication number Publication date
ES2424023T3 (es) 2013-09-26
TW200934769A (en) 2009-08-16
US20100216846A1 (en) 2010-08-26
RU2474579C2 (ru) 2013-02-10
RU2010119459A (ru) 2011-11-27
CN101827836A (zh) 2010-09-08
CN101827836B (zh) 2014-02-19
CA2697974C (en) 2015-06-30
AR070661A1 (es) 2010-04-28
AU2008313776A1 (en) 2009-04-23
IL205101A0 (en) 2010-11-30
EP2212309A1 (en) 2010-08-04
PE20090877A1 (es) 2009-07-02
WO2009050186A1 (en) 2009-04-23
HK1146281A1 (en) 2011-05-27
AU2008313776B2 (en) 2013-12-05
IL205101A (en) 2015-02-26
MX2010004177A (es) 2010-05-03
TWI438198B (zh) 2014-05-21
PA8799801A1 (es) 2009-05-15
CA2697974A1 (en) 2009-04-23
US8440701B2 (en) 2013-05-14
JP2011500625A (ja) 2011-01-06
EP2212309B1 (en) 2013-06-19

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