CL2008000474A1 - Compuestos derivados de azonia-biciclo-[2.2.2]octano, moduladores del receptor m3; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como epoc, asma, sindrome del intestino irritable, entre otras. - Google Patents
Compuestos derivados de azonia-biciclo-[2.2.2]octano, moduladores del receptor m3; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como epoc, asma, sindrome del intestino irritable, entre otras.Info
- Publication number
- CL2008000474A1 CL2008000474A1 CL200800474A CL2008000474A CL2008000474A1 CL 2008000474 A1 CL2008000474 A1 CL 2008000474A1 CL 200800474 A CL200800474 A CL 200800474A CL 2008000474 A CL2008000474 A CL 2008000474A CL 2008000474 A1 CL2008000474 A1 CL 2008000474A1
- Authority
- CL
- Chile
- Prior art keywords
- biciclo
- octano
- azonia
- copd
- asthma
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 210000000936 intestine Anatomy 0.000 title 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0702994A GB0702994D0 (en) | 2007-02-15 | 2007-02-15 | Compound and thier use |
| GB0722678A GB0722678D0 (en) | 2007-11-19 | 2007-11-19 | Compounds and their use II |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2008000474A1 true CL2008000474A1 (es) | 2008-08-22 |
Family
ID=39323641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200800474A CL2008000474A1 (es) | 2007-02-15 | 2008-02-14 | Compuestos derivados de azonia-biciclo-[2.2.2]octano, moduladores del receptor m3; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como epoc, asma, sindrome del intestino irritable, entre otras. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20100056565A1 (es) |
| EP (1) | EP2121688A1 (es) |
| JP (1) | JP2010519193A (es) |
| KR (1) | KR20090110353A (es) |
| CN (1) | CN101657452A (es) |
| AR (1) | AR065344A1 (es) |
| AU (1) | AU2008215924B2 (es) |
| BR (1) | BRPI0807913A2 (es) |
| CA (1) | CA2676581A1 (es) |
| CL (1) | CL2008000474A1 (es) |
| CO (1) | CO6190612A2 (es) |
| EC (1) | ECSP099573A (es) |
| IL (1) | IL199971A0 (es) |
| MX (1) | MX2009008323A (es) |
| NZ (1) | NZ578489A (es) |
| PE (1) | PE20090357A1 (es) |
| RU (1) | RU2009133258A (es) |
| SA (1) | SA08290066B1 (es) |
| TW (1) | TW200843759A (es) |
| UY (1) | UY30916A1 (es) |
| WO (1) | WO2008099186A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200825084A (en) | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
| WO2009098453A1 (en) * | 2008-02-06 | 2009-08-13 | Astrazeneca Ab | Azonia bicycloalkanes as m3 muscarinic acetylcholin receptor antagonists |
| EP2300464A1 (en) | 2008-05-13 | 2011-03-30 | AstraZeneca AB | Quinuclidine derivatives as muscarinic m3 receptor antagonists |
| WO2010018352A1 (en) * | 2008-08-12 | 2010-02-18 | Argenta Discovery Limited | Heterocyclic compounds used in the treatment of diseases where enhanced m3 receptor activation is implicated |
| GB0814728D0 (en) * | 2008-08-12 | 2008-09-17 | Argenta Discovery Ltd | New combination |
| GB0814729D0 (en) * | 2008-08-12 | 2008-09-17 | Argenta Discovery Ltd | New combination |
| BRPI0917978A2 (pt) * | 2008-08-12 | 2015-11-17 | Astrazeneca Ab | sal de 2-hidróxi-etanossulfonato |
| TW201036957A (en) | 2009-02-20 | 2010-10-16 | Astrazeneca Ab | Novel salt 628 |
| CN104418851A (zh) * | 2013-09-02 | 2015-03-18 | 上海龙翔生物医药开发有限公司 | 奎宁环衍生物的制备方法及纯化方法 |
| MX2017002500A (es) * | 2014-08-26 | 2017-05-23 | Astellas Pharma Inc | Derivado de 2-aminotiazol o sal del mismo. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8334494D0 (en) * | 1983-12-24 | 1984-02-01 | Tanabe Seiyaku Co | Carbostyril derivatives |
| NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
| IL88846A0 (en) * | 1988-01-08 | 1989-07-31 | Merck Sharp & Dohme | Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them |
| GB9603755D0 (en) * | 1996-02-22 | 1996-04-24 | Pfizer Ltd | Therapeutic agents |
| DE19856475A1 (de) * | 1998-11-27 | 2000-05-31 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| US20020052312A1 (en) * | 2000-05-30 | 2002-05-02 | Reiss Theodore F. | Combination therapy of chronic obstructive pulmonary disease using muscarinic receptor antagonists |
| PT1353919E (pt) * | 2000-12-28 | 2006-11-30 | Almirall Prodesfarma Ag | Novos derivados de quinuclidina e composições medicinais contendo os mesmos |
| US7220741B2 (en) * | 2002-09-30 | 2007-05-22 | Neurosearch A/S | 1,4-diazabicycloalkane derivatives, their preparation and use |
| KR20050062575A (ko) * | 2002-09-30 | 2005-06-23 | 뉴로서치 에이/에스 | 신규한 1,4-디아자바이사이클로알칸 유도체, 이의 제법 및용도 |
| US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| ES2239546B1 (es) * | 2004-03-15 | 2006-12-01 | Almirall Prodesfarma, S.A. | Nuevos esteres de quinuclidina cuaternizados. |
| GB0516313D0 (en) * | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
-
2008
- 2008-02-14 CA CA002676581A patent/CA2676581A1/en not_active Abandoned
- 2008-02-14 CL CL200800474A patent/CL2008000474A1/es unknown
- 2008-02-14 MX MX2009008323A patent/MX2009008323A/es active IP Right Grant
- 2008-02-14 AU AU2008215924A patent/AU2008215924B2/en not_active Ceased
- 2008-02-14 BR BRPI0807913-7A2A patent/BRPI0807913A2/pt not_active IP Right Cessation
- 2008-02-14 EP EP08709410A patent/EP2121688A1/en not_active Withdrawn
- 2008-02-14 UY UY30916A patent/UY30916A1/es not_active Application Discontinuation
- 2008-02-14 AR ARP080100627A patent/AR065344A1/es unknown
- 2008-02-14 US US12/523,609 patent/US20100056565A1/en not_active Abandoned
- 2008-02-14 CN CN200880012083A patent/CN101657452A/zh active Pending
- 2008-02-14 WO PCT/GB2008/000519 patent/WO2008099186A1/en not_active Ceased
- 2008-02-14 PE PE2008000323A patent/PE20090357A1/es not_active Application Discontinuation
- 2008-02-14 NZ NZ578489A patent/NZ578489A/en not_active IP Right Cessation
- 2008-02-14 RU RU2009133258/04A patent/RU2009133258A/ru not_active Application Discontinuation
- 2008-02-14 JP JP2009549470A patent/JP2010519193A/ja active Pending
- 2008-02-14 TW TW097105181A patent/TW200843759A/zh unknown
- 2008-02-14 KR KR1020097017018A patent/KR20090110353A/ko not_active Withdrawn
- 2008-02-16 SA SA08290066A patent/SA08290066B1/ar unknown
-
2009
- 2009-07-20 IL IL199971A patent/IL199971A0/en unknown
- 2009-07-28 CO CO09078490A patent/CO6190612A2/es not_active Application Discontinuation
- 2009-08-12 EC EC2009009573A patent/ECSP099573A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SA08290066B1 (ar) | 2011-05-14 |
| AU2008215924A1 (en) | 2008-08-21 |
| RU2009133258A (ru) | 2011-03-20 |
| JP2010519193A (ja) | 2010-06-03 |
| EP2121688A1 (en) | 2009-11-25 |
| CN101657452A (zh) | 2010-02-24 |
| UY30916A1 (es) | 2008-09-30 |
| CO6190612A2 (es) | 2010-08-19 |
| BRPI0807913A2 (pt) | 2014-06-17 |
| PE20090357A1 (es) | 2009-04-01 |
| AU2008215924B2 (en) | 2011-04-21 |
| NZ578489A (en) | 2011-05-27 |
| WO2008099186A1 (en) | 2008-08-21 |
| MX2009008323A (es) | 2009-08-13 |
| ECSP099573A (es) | 2009-12-28 |
| TW200843759A (en) | 2008-11-16 |
| IL199971A0 (en) | 2010-04-15 |
| CA2676581A1 (en) | 2008-08-21 |
| AR065344A1 (es) | 2009-06-03 |
| WO2008099186A8 (en) | 2008-11-13 |
| US20100056565A1 (en) | 2010-03-04 |
| KR20090110353A (ko) | 2009-10-21 |
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