CL2007001894A1 - Formulacion oftalmica topica que comprende: 0,1% de dexametasona, 0,3% de clorhidrato de ciprofloxacino, cloruro de sodio, 6% de hidroxipropil-beta-ciclodextrina, 0,15% de sulfato de sodio, 0,05% de edetato disodico, 0,022% de cloruro de benzalconio al 50% y 0,100ml/100ml de polisorbato 80; util para tratar infecciones oculares. - Google Patents

Formulacion oftalmica topica que comprende: 0,1% de dexametasona, 0,3% de clorhidrato de ciprofloxacino, cloruro de sodio, 6% de hidroxipropil-beta-ciclodextrina, 0,15% de sulfato de sodio, 0,05% de edetato disodico, 0,022% de cloruro de benzalconio al 50% y 0,100ml/100ml de polisorbato 80; util para tratar infecciones oculares.

Info

Publication number: CL2007001894A1
Authority: CL; Chile
Prior art keywords: dexamethasone; polysorbate; chloride; cyclodextrin; useful
Prior art date: 2006-06-27

Application number

CL2007001894A

Other languages

English (en)

Spanish (es)

Inventor

De Dios Quintana Hau Juan

Ruben Tornero Montano Jose

Martin Baiza Duran Leopoldo

Patricia Rodriguez Franco Norma

R Jaime

Original Assignee

Arturo Jimenez Bayardo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-27

Filing date

2007-06-27

Publication date

2008-01-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38845821&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2007001894(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-06-27 Application filed by Arturo Jimenez Bayardo filed Critical Arturo Jimenez Bayardo

2008-01-04 Publication of CL2007001894A1 publication Critical patent/CL2007001894A1/es

Links

FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 title abstract 4
ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 title abstract 2
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 title abstract 2
229960000686 benzalkonium chloride Drugs 0.000 title abstract 2
CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 title abstract 2
DIOIOSKKIYDRIQ-UHFFFAOYSA-N ciprofloxacin hydrochloride Chemical compound Cl.C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 DIOIOSKKIYDRIQ-UHFFFAOYSA-N 0.000 title abstract 2
229960001229 ciprofloxacin hydrochloride Drugs 0.000 title abstract 2
UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 title abstract 2
229960003957 dexamethasone Drugs 0.000 title abstract 2
238000009472 formulation Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 title abstract 2
239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 title abstract 2
229920000053 polysorbate 80 Polymers 0.000 title abstract 2
229940068968 polysorbate 80 Drugs 0.000 title abstract 2
239000011780 sodium chloride Substances 0.000 title abstract 2
229910052938 sodium sulfate Inorganic materials 0.000 title abstract 2
235000011152 sodium sulphate Nutrition 0.000 title abstract 2
208000001860 Eye Infections Diseases 0.000 title 1
229940124274 edetate disodium Drugs 0.000 title 1
208000011323 eye infectious disease Diseases 0.000 title 1
230000000699 topical effect Effects 0.000 title 1
ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 title 1
238000011200 topical administration Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

CL2007001894A 2006-06-27 2007-06-27 Formulacion oftalmica topica que comprende: 0,1% de dexametasona, 0,3% de clorhidrato de ciprofloxacino, cloruro de sodio, 6% de hidroxipropil-beta-ciclodextrina, 0,15% de sulfato de sodio, 0,05% de edetato disodico, 0,022% de cloruro de benzalconio al 50% y 0,100ml/100ml de polisorbato 80; util para tratar infecciones oculares. CL2007001894A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/MX2006/000062 WO2008002117A1 (fr)	2006-06-27	2006-06-27	Solution ophtalmique de ciprofloxacine et de dexaméthasone

Publications (1)

Publication Number	Publication Date
CL2007001894A1 true CL2007001894A1 (es)	2008-01-04

Family

ID=38845821

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL2007001894A CL2007001894A1 (es)	2006-06-27	2007-06-27	Formulacion oftalmica topica que comprende: 0,1% de dexametasona, 0,3% de clorhidrato de ciprofloxacino, cloruro de sodio, 6% de hidroxipropil-beta-ciclodextrina, 0,15% de sulfato de sodio, 0,05% de edetato disodico, 0,022% de cloruro de benzalconio al 50% y 0,100ml/100ml de polisorbato 80; util para tratar infecciones oculares.

Country Status (3)

Country	Link
CL (1)	CL2007001894A1 (fr)
PE (1)	PE20080347A1 (fr)
WO (1)	WO2008002117A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN107970244B (zh) *	2016-10-21	2020-07-14	武汉武药科技有限公司	一种含有环丙沙星和地塞米松的组合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6740664B2 (en) *	1998-09-30	2004-05-25	Alcon, Inc.	Methods for treating otic and ophthalmic infections
CA2428189A1 (fr) *	2000-11-15	2002-05-23	Mainde Chandrashekhar	Medicament combine
WO2004069280A1 (fr) *	2003-02-06	2004-08-19	Cipla Ltd	Complexes d'inclusion pharmaceutiques contenant un steroide et un agent antibacterien facultatif
WO2004087043A2 (fr) *	2003-02-21	2004-10-14	Sun Pharmaceutical Industries Limited	Composition ophtalmique stable

2006
- 2006-06-27 WO PCT/MX2006/000062 patent/WO2008002117A1/fr not_active Ceased
2007
- 2007-06-27 PE PE2007000833A patent/PE20080347A1/es not_active Application Discontinuation
- 2007-06-27 CL CL2007001894A patent/CL2007001894A1/es unknown

Also Published As

Publication number	Publication date
PE20080347A1 (es)	2008-04-11
WO2008002117A1 (fr)	2008-01-03

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