CA3265564A1 - Bicycles substitués utilisés comme inhibiteurs de hset - Google Patents
Bicycles substitués utilisés comme inhibiteurs de hsetInfo
- Publication number
- CA3265564A1 CA3265564A1 CA3265564A CA3265564A CA3265564A1 CA 3265564 A1 CA3265564 A1 CA 3265564A1 CA 3265564 A CA3265564 A CA 3265564A CA 3265564 A CA3265564 A CA 3265564A CA 3265564 A1 CA3265564 A1 CA 3265564A1
- Authority
- CA
- Canada
- Prior art keywords
- hset
- inhibitors
- bicycles
- substituted
- substituted bicycles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22191702 | 2022-08-23 | ||
| PCT/EP2023/072876 WO2024042007A1 (fr) | 2022-08-23 | 2023-08-21 | Bicycles substitués utilisés comme inhibiteurs de hset |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3265564A1 true CA3265564A1 (fr) | 2024-02-29 |
Family
ID=83049902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3265564A Pending CA3265564A1 (fr) | 2022-08-23 | 2023-08-21 | Bicycles substitués utilisés comme inhibiteurs de hset |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4577537A1 (fr) |
| JP (1) | JP2025529897A (fr) |
| CN (1) | CN120091998A (fr) |
| AR (1) | AR130226A1 (fr) |
| AU (1) | AU2023328866A1 (fr) |
| CA (1) | CA3265564A1 (fr) |
| TW (1) | TW202421116A (fr) |
| WO (1) | WO2024042007A1 (fr) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7504413B2 (en) * | 2004-05-06 | 2009-03-17 | Cytokinetics, Inc. | N-(4-(imidazo[1,2A]pyridin-YL)phenethyl)benzamide inhibitors of the mitotic kinesin CENP-E for treating certain cellular proliferation diseases |
| JP2008510013A (ja) * | 2004-08-18 | 2008-04-03 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害剤 |
| CN119421877A (zh) * | 2022-01-10 | 2025-02-11 | 默克专利股份公司 | 作为hset抑制剂的取代杂环化合物 |
-
2023
- 2023-08-16 AR ARP230102170A patent/AR130226A1/es unknown
- 2023-08-21 WO PCT/EP2023/072876 patent/WO2024042007A1/fr not_active Ceased
- 2023-08-21 AU AU2023328866A patent/AU2023328866A1/en active Pending
- 2023-08-21 EP EP23757923.0A patent/EP4577537A1/fr active Pending
- 2023-08-21 CA CA3265564A patent/CA3265564A1/fr active Pending
- 2023-08-21 CN CN202380074493.0A patent/CN120091998A/zh active Pending
- 2023-08-21 JP JP2025511776A patent/JP2025529897A/ja active Pending
- 2023-08-22 TW TW112131450A patent/TW202421116A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024042007A1 (fr) | 2024-02-29 |
| AU2023328866A1 (en) | 2025-04-03 |
| TW202421116A (zh) | 2024-06-01 |
| EP4577537A1 (fr) | 2025-07-02 |
| AR130226A1 (es) | 2024-11-20 |
| JP2025529897A (ja) | 2025-09-09 |
| CN120091998A (zh) | 2025-06-03 |
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