CA3016037A1 - Methods, compositions, and devices for information storage - Google Patents
Methods, compositions, and devices for information storage Download PDFInfo
- Publication number
- CA3016037A1 CA3016037A1 CA3016037A CA3016037A CA3016037A1 CA 3016037 A1 CA3016037 A1 CA 3016037A1 CA 3016037 A CA3016037 A CA 3016037A CA 3016037 A CA3016037 A CA 3016037A CA 3016037 A1 CA3016037 A1 CA 3016037A1
- Authority
- CA
- Canada
- Prior art keywords
- dna
- nanopore
- polymer
- nanochip
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00511—Walls of reactor vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/10—Nucleotidyl transfering
- C12Q2521/131—Terminal transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/116—Nucleic acid detection characterized by the use of physical, structural and functional properties electrical properties of nucleic acids, e.g. impedance, conductivity or resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y599/00—Other isomerases (5.99)
- C12Y599/01—Other isomerases (5.99.1)
- C12Y599/01002—DNA topoisomerase (5.99.1.2)
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/12—Computing arrangements based on biological models using genetic models
- G06N3/123—DNA computing
-
- G—PHYSICS
- G11—INFORMATION STORAGE
- G11C—STATIC STORES
- G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
- G11C13/0002—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
- G11C13/0009—RRAM elements whose operation depends upon chemical change
- G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
-
- G—PHYSICS
- G11—INFORMATION STORAGE
- G11C—STATIC STORES
- G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
- G11C13/0002—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
- G11C13/0009—RRAM elements whose operation depends upon chemical change
- G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
- G11C13/0019—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Theoretical Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- General Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Data Mining & Analysis (AREA)
- Evolutionary Computation (AREA)
- Computing Systems (AREA)
- Artificial Intelligence (AREA)
- Mathematical Physics (AREA)
- Software Systems (AREA)
- Electrochemistry (AREA)
- Computational Linguistics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662301538P | 2016-02-29 | 2016-02-29 | |
| US62/301,538 | 2016-02-29 | ||
| US201662415430P | 2016-10-31 | 2016-10-31 | |
| US62/415,430 | 2016-10-31 | ||
| PCT/US2017/020044 WO2017151680A2 (en) | 2016-02-29 | 2017-02-28 | Methods, compositions, and devices for information storage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3016037A1 true CA3016037A1 (en) | 2017-09-08 |
Family
ID=59743186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3016037A Pending CA3016037A1 (en) | 2016-02-29 | 2017-02-28 | Methods, compositions, and devices for information storage |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP3423597A4 (ru) |
| JP (2) | JP7546345B2 (ru) |
| KR (2) | KR20180123062A (ru) |
| CN (1) | CN109415766A (ru) |
| AU (2) | AU2017227608B2 (ru) |
| BR (1) | BR112018067903A2 (ru) |
| CA (1) | CA3016037A1 (ru) |
| IL (1) | IL261424B (ru) |
| MX (2) | MX2018010388A (ru) |
| PH (1) | PH12018501843A1 (ru) |
| RU (2) | RU2022101599A (ru) |
| SG (1) | SG11201807334SA (ru) |
| WO (1) | WO2017151680A2 (ru) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102796872B1 (ko) | 2016-01-28 | 2025-04-15 | 로스웰 엠이 아이엔씨. | 대규모 분자 전자소자 센서 어레이들을 이용하여 분석물들을 측정하는 방법들 및 장치 |
| JP7080489B2 (ja) | 2016-01-28 | 2022-06-06 | ロズウェル バイオテクノロジーズ,インコーポレイテッド | 超パラレルdna配列決定装置 |
| JP6854532B2 (ja) | 2016-02-09 | 2021-04-07 | ロズウェル バイオテクノロジーズ,インコーポレイテッド | 電子的、標識フリーのdnaおよびゲノムシークエンシング |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| US10438662B2 (en) * | 2016-02-29 | 2019-10-08 | Iridia, Inc. | Methods, compositions, and devices for information storage |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| KR102622275B1 (ko) | 2017-01-10 | 2024-01-05 | 로스웰 바이오테크놀로지스 인코포레이티드 | Dna 데이터 저장을 위한 방법들 및 시스템들 |
| KR102601324B1 (ko) | 2017-01-19 | 2023-11-10 | 로스웰 바이오테크놀로지스 인코포레이티드 | 2차원 레이어 재료를 포함하는 솔리드 스테이트 시퀀싱 디바이스들 |
| WO2018200687A1 (en) | 2017-04-25 | 2018-11-01 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| EP4023764A3 (en) | 2017-05-09 | 2022-09-21 | Roswell Biotechnologies, Inc. | Binding probe circuits for molecular sensors |
| KR102583062B1 (ko) | 2017-05-31 | 2023-09-25 | 몰레큘러 어셈블리즈, 인크. | 동종중합체 인코딩된 핵산 메모리 |
| US11612873B2 (en) | 2017-05-31 | 2023-03-28 | Molecular Assemblies, Inc. | Homopolymer encoded nucleic acid memory |
| US11174512B2 (en) | 2017-05-31 | 2021-11-16 | Molecular Assemblies, Inc. | Homopolymer encoded nucleic acid memory |
| EP3676389A4 (en) | 2017-08-30 | 2021-06-02 | Roswell Biotechnologies, Inc | PROCESSIVE ENZYMATIC MOLECULAR ELECTRONIC SENSORS FOR STORING DNA DATA |
| KR102717872B1 (ko) * | 2017-10-10 | 2024-10-14 | 로스웰 엠이 아이엔씨. | 무증폭 dna 데이터 저장을 위한 방법, 장치 및 시스템 |
| KR102804057B1 (ko) * | 2018-01-04 | 2025-05-07 | 트위스트 바이오사이언스 코포레이션 | Dna 기반 디지털 정보 저장 |
| GB201801768D0 (en) | 2018-02-02 | 2018-03-21 | Oxford Nanopore Tech Ltd | Synthesis method |
| EP3547315B1 (en) * | 2018-03-26 | 2021-01-27 | IMEC vzw | Method of storing data |
| CN113302700B (zh) * | 2018-09-07 | 2024-10-08 | 艾瑞迪亚公司 | 用于写入和读取存储在聚合物中的数据的改进的系统和方法 |
| KR102653412B1 (ko) * | 2019-03-29 | 2024-04-02 | 팔로젠 인코포레이티드 | 나노포어 디바이스 및 이를 사용한 바이오 합성 방법들 |
| US11655465B1 (en) | 2019-05-02 | 2023-05-23 | Iridia, Inc. | Enzymes and systems for synthesizing DNA |
| TWI860366B (zh) * | 2019-06-19 | 2024-11-01 | 美商伊路米納有限公司 | 儀器中的試劑交換 |
| US11837302B1 (en) | 2020-08-07 | 2023-12-05 | Iridia, Inc. | Systems and methods for writing and reading data stored in a polymer using nano-channels |
| CN114196661B (zh) * | 2021-11-04 | 2023-08-11 | 北京全式金生物技术股份有限公司 | 一种重组拓扑异构酶及其在构建测序文库中的应用 |
| US12487229B2 (en) * | 2021-12-08 | 2025-12-02 | Western Digital Technologies, Inc. | Devices, systems, and methods of using smart fluids to control molecule speeds |
| US11892445B2 (en) * | 2021-12-08 | 2024-02-06 | Western Digital Technologies, Inc. | Devices, systems, and methods of using smart fluids to control translocation speed through a nanopore |
| CN117079689A (zh) * | 2022-05-10 | 2023-11-17 | 密码子(杭州)科技有限公司 | 分子模块组装设备和分子模块组装方法 |
| US12461064B2 (en) | 2023-06-23 | 2025-11-04 | Western Digital Technologies, Inc. | Magnetic control of molecule translocation speed through a nanopore |
| WO2025212833A2 (en) * | 2024-04-03 | 2025-10-09 | Catalog Technologies, Inc. | Liquid formulations for dna writing |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681702A (en) * | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| ATE283353T1 (de) * | 1997-06-12 | 2004-12-15 | Sloan Kettering Inst Cancer | Kovalente bindung von dna zu rna strängen katalysiert durch vaccinia topoisomerase |
| CN101173276A (zh) * | 2000-12-08 | 2008-05-07 | 茵维特罗根公司 | 利用多识别位点合成核酸分子的方法和组合物 |
| US20040001371A1 (en) | 2002-06-26 | 2004-01-01 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Information storage and retrieval device using macromolecules as storage media |
| US7390622B2 (en) * | 2003-10-16 | 2008-06-24 | Hai Kang Life Corporation Limited | Apparatus and methods for detecting nucleic acid in biological samples |
| BRPI0417830B1 (pt) * | 2003-12-17 | 2021-02-17 | Praecis Pharmaceuticals Inc | métodos para síntese de uma molécula compreendendo uma porção funcional operativamente ligada a um oligonucleotídeo de codificação |
| US8202689B2 (en) * | 2005-05-11 | 2012-06-19 | The Regents Of The University Of California | Nanofabrication processes and devices for the controlled assembly of functionalized nanostructures |
| US20060286024A1 (en) * | 2005-06-15 | 2006-12-21 | Baker R Terry K | Synthesis and cleaving of carbon nanochips |
| DK2915564T3 (da) * | 2007-09-28 | 2021-02-08 | Alexion Pharma Inc | Antidoter mod faktor XA-inhibitorer og fremgangsmåder til anvendelse deraf |
| BRPI1007214A8 (pt) * | 2009-01-30 | 2022-12-20 | Oxford Nanopore Tech Ltd | Adaptador para sequenciar ácidos nucleicos, par de adaptadores, kit, construto de ácido nucleico, e, métodos para preparar um adaptador, um construto de ácido nucleico, e um construto de dequência, e para sequenciar ácido nucleico de fita dupla. |
| WO2012033524A2 (en) * | 2010-09-07 | 2012-03-15 | The Regents Of The University Of California | Control of dna movement in a nanopore at one nucleotide precision by a processive enzyme |
| CA2861457A1 (en) * | 2012-01-20 | 2013-07-25 | Genia Technologies, Inc. | Nanopore based molecular detection and sequencing |
| US9322820B2 (en) * | 2013-03-14 | 2016-04-26 | Wisconsin Alumni Research Foundation | System and apparatus for nanopore sequencing |
-
2017
- 2017-02-28 KR KR1020187028197A patent/KR20180123062A/ko active Pending
- 2017-02-28 KR KR1020257002997A patent/KR20250024857A/ko active Pending
- 2017-02-28 MX MX2018010388A patent/MX2018010388A/es unknown
- 2017-02-28 AU AU2017227608A patent/AU2017227608B2/en active Active
- 2017-02-28 SG SG11201807334SA patent/SG11201807334SA/en unknown
- 2017-02-28 JP JP2018546548A patent/JP7546345B2/ja active Active
- 2017-02-28 CA CA3016037A patent/CA3016037A1/en active Pending
- 2017-02-28 RU RU2022101599A patent/RU2022101599A/ru unknown
- 2017-02-28 CN CN201780025380.6A patent/CN109415766A/zh active Pending
- 2017-02-28 BR BR112018067903-8A patent/BR112018067903A2/pt not_active Application Discontinuation
- 2017-02-28 WO PCT/US2017/020044 patent/WO2017151680A2/en not_active Ceased
- 2017-02-28 RU RU2018134197A patent/RU2765308C2/ru active
- 2017-02-28 EP EP17760661.3A patent/EP3423597A4/en active Pending
-
2018
- 2018-08-28 IL IL261424A patent/IL261424B/en unknown
- 2018-08-29 MX MX2022010682A patent/MX2022010682A/es unknown
- 2018-08-29 PH PH12018501843A patent/PH12018501843A1/en unknown
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2022
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- 2022-11-09 AU AU2022268325A patent/AU2022268325B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201807334SA (en) | 2018-09-27 |
| RU2018134197A (ru) | 2020-04-01 |
| AU2022268325B2 (en) | 2024-09-19 |
| AU2017227608A1 (en) | 2018-09-27 |
| RU2022101599A (ru) | 2022-02-25 |
| EP3423597A2 (en) | 2019-01-09 |
| KR20250024857A (ko) | 2025-02-19 |
| PH12018501843A1 (en) | 2019-05-15 |
| RU2765308C2 (ru) | 2022-01-28 |
| CN109415766A (zh) | 2019-03-01 |
| EP3423597A4 (en) | 2020-03-04 |
| JP7546345B2 (ja) | 2024-09-06 |
| WO2017151680A3 (en) | 2017-10-12 |
| JP2019512480A (ja) | 2019-05-16 |
| WO2017151680A2 (en) | 2017-09-08 |
| MX2022010682A (es) | 2022-09-23 |
| AU2017227608B2 (en) | 2023-06-01 |
| RU2018134197A3 (ru) | 2021-07-02 |
| AU2022268325A1 (en) | 2022-12-15 |
| BR112018067903A2 (pt) | 2019-04-16 |
| MX2018010388A (es) | 2019-03-06 |
| JP2022095695A (ja) | 2022-06-28 |
| KR20180123062A (ko) | 2018-11-14 |
| IL261424B (en) | 2021-08-31 |
| IL261424A (en) | 2018-10-31 |
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