[go: up one dir, main page]

CA2669123A1 - Inhibiteurs d'acat et leur utilisation dans la prevention ou le traitement de la fibrose - Google Patents

Inhibiteurs d'acat et leur utilisation dans la prevention ou le traitement de la fibrose Download PDF

Info

Publication number
CA2669123A1
CA2669123A1 CA002669123A CA2669123A CA2669123A1 CA 2669123 A1 CA2669123 A1 CA 2669123A1 CA 002669123 A CA002669123 A CA 002669123A CA 2669123 A CA2669123 A CA 2669123A CA 2669123 A1 CA2669123 A1 CA 2669123A1
Authority
CA
Canada
Prior art keywords
fibrosis
tissue
acat inhibitor
collagen
acat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002669123A
Other languages
English (en)
Inventor
Siegfried Hekimi
Abdelmadjid K. Hihi
Robyn S. Branicky
Xihua Jia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sosei Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2669123A1 publication Critical patent/CA2669123A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002669123A 2006-11-13 2007-11-13 Inhibiteurs d'acat et leur utilisation dans la prevention ou le traitement de la fibrose Abandoned CA2669123A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US85834906P 2006-11-13 2006-11-13
US60/858,349 2006-11-13
US93575307P 2007-08-29 2007-08-29
US60/935,753 2007-08-29
PCT/CA2007/002032 WO2008058383A1 (fr) 2006-11-13 2007-11-13 Inhibiteurs d'acat et leur utilisation dans la prévention ou le traitement de la fibrose

Publications (1)

Publication Number Publication Date
CA2669123A1 true CA2669123A1 (fr) 2008-05-22

Family

ID=39401277

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002669123A Abandoned CA2669123A1 (fr) 2006-11-13 2007-11-13 Inhibiteurs d'acat et leur utilisation dans la prevention ou le traitement de la fibrose

Country Status (8)

Country Link
EP (1) EP1981493A4 (fr)
JP (1) JP2010509247A (fr)
KR (1) KR20100014267A (fr)
AU (1) AU2007321667A1 (fr)
BR (1) BRPI0718630A2 (fr)
CA (1) CA2669123A1 (fr)
IL (1) IL198721A0 (fr)
WO (1) WO2008058383A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625890B2 (en) 2005-11-10 2009-12-01 Smithkline Beecham Corp. Substituted imidazo[4,5-c]pyridine compounds as Akt inhibitors
WO2008138350A1 (fr) * 2007-05-14 2008-11-20 Sygehuset Glostrup Prévention d'une fibrose intra-oculaire
US8614991B2 (en) 2008-04-25 2013-12-24 Kyocera Corporation Wireless communication apparatus and communication apparatus
KR20130113921A (ko) * 2010-05-19 2013-10-16 코와 가부시키가이샤 비알코올성 지방성 간염의 예방 및/또는 치료제
US9164084B2 (en) 2012-01-31 2015-10-20 Purdue Research Foundation Methods for determining aggressiveness of a cancer and treatment thereof
CN102670796A (zh) * 2012-05-22 2012-09-19 广西天天乐药业股份有限公司 一种治疗脾胃虚弱的中药及其制备方法
GB201917498D0 (en) * 2019-11-29 2020-01-15 Ucl Business Ltd Treatment o f hepatitis b virus (hbv) infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2358400C (fr) * 1999-01-05 2012-05-15 Nancy A. Noble Procedes de traitement d'etats associes a l'accumulation d'un excedent de matrice extracellulaire
RU2358734C2 (ru) * 2003-08-29 2009-06-20 Кова Ко., Лтд. Способ стабилизации бляшки с высоким содержанием липидов и способ профилактики ее разрушения

Also Published As

Publication number Publication date
AU2007321667A1 (en) 2008-05-22
EP1981493A4 (fr) 2009-11-11
WO2008058383A1 (fr) 2008-05-22
BRPI0718630A2 (pt) 2014-05-27
EP1981493A1 (fr) 2008-10-22
KR20100014267A (ko) 2010-02-10
JP2010509247A (ja) 2010-03-25
IL198721A0 (en) 2010-02-17

Similar Documents

Publication Publication Date Title
KR100552043B1 (ko) 푸마질롤 유도체를 포함하는 비만치료용 조성물
US9579315B2 (en) Methods of treating obstructive lung diseases using bitter tastants
CA2669123A1 (fr) Inhibiteurs d'acat et leur utilisation dans la prevention ou le traitement de la fibrose
Abidi et al. Nigella sativa, a traditional Tunisian herbal medicine, attenuates bleomycin-induced pulmonary fibrosis in a rat model
MX2011010631A (es) Metodos y composiciones de inhibidores de quinasa pi-3 para tratar fibrosis.
JPWO2021066144A1 (ja) ヘテロシクリデンアセトアミド誘導体含有医薬
AU2025205402A1 (en) New oral pharmaceutical composition and dose regimen for the therapy of progressive fibrosing interstitial lung diseases
KR101340940B1 (ko) 데커시놀 또는 데커시놀 엔젤레이트를 함유하는 퇴행성 신경질환의 예방 또는 치료용 조성물
CN103221043A (zh) 用于治疗神经元连接发育障碍的erk抑制剂
US9505757B2 (en) Pharmaceutical composition comprising bicyclic pyridinol derivatives for preventing or treating diseases caused by angiogenesis
CN101129394B (zh) 秦皮甲素预防和/或治疗心脑血管疾病的新用途
Zhang et al. The Tan-Re-Qing Capsule mitigates acute lung injury by suppressing the NLRP3 inflammasome and MAPK/NF-κB signaling pathways
US20220202801A1 (en) Use of compound in preparation of drug for treating atherosclerosis
KR102057441B1 (ko) 벤조[d]싸이아졸 유도체 또는 이의 염을 유효성분으로 포함하는 면역세포 이동 관련 질환의 예방 또는 치료용 약학적 조성물
Zhang et al. Artemisinin-hydroxychloroquine combination from traditional antimalarial medicine attenuates pulmonary fibrosis via PI3K/AKT/GSK3β-mediated inhibition of epithelial-mesenchymal transition
US20250136661A1 (en) Pharmaceutical composition comprising adipose tissue-derived extracellular vesicle and biologic and use of pharmaceutical composition for treating arthritis
CN117720620B (zh) 小分子多肽和其药物组合物、其制药用途
US6348488B1 (en) Remedies for motor dysfunction and GAPDH expression inhibitors
US8507506B2 (en) Theophylline derivative inhibits osteoporosis
Mo et al. Bisabolangelone targets Colony-stimulating factor 1 receptor (CSF1R) to impede osteoclastogenesis and attenuate estrogen-deficiency bone loss
CN101904843B (zh) 化合物制备骨破坏抑制剂的用途
CN120131616A (zh) 阿维a酸在制备治疗nlrp3炎症小体介导的疾病的药物中的应用、预防和/或治疗nlrp3炎症小体介导的疾病的药物组合物
HK40084623A (en) Use of glycerol phospholipids in the prevention and treatment of hyperlipidemia, atherosclerosis, non-alcoholic fatty liver and obesity
CN119424407A (zh) 3,5,6,7,8,3’,4’-七甲氧基黄酮在制备预防或治疗肺纤维化的药物中的应用
KR20170094584A (ko) 레바미피드 전구체를 포함하는 면역질환 및 대사성질환의 예방 또는 치료를 위한 경구투여용 약제학적 조성물

Legal Events

Date Code Title Description
FZDE Discontinued