CA2500313A1 - Composition polymere et formes posologiques la comprenant - Google Patents
Composition polymere et formes posologiques la comprenant Download PDFInfo
- Publication number
- CA2500313A1 CA2500313A1 CA002500313A CA2500313A CA2500313A1 CA 2500313 A1 CA2500313 A1 CA 2500313A1 CA 002500313 A CA002500313 A CA 002500313A CA 2500313 A CA2500313 A CA 2500313A CA 2500313 A1 CA2500313 A1 CA 2500313A1
- Authority
- CA
- Canada
- Prior art keywords
- molecular weight
- water soluble
- high molecular
- composition
- soluble polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract 34
- 239000002552 dosage form Substances 0.000 title claims abstract 21
- 229920000642 polymer Polymers 0.000 title claims abstract 13
- 229920003169 water-soluble polymer Polymers 0.000 claims abstract 22
- 239000011159 matrix material Substances 0.000 claims abstract 20
- 238000000034 method Methods 0.000 claims 13
- 239000006185 dispersion Substances 0.000 claims 7
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 6
- 235000010418 carrageenan Nutrition 0.000 claims 6
- 239000000679 carrageenan Substances 0.000 claims 6
- 229920001525 carrageenan Polymers 0.000 claims 6
- 229940113118 carrageenan Drugs 0.000 claims 6
- 150000001767 cationic compounds Chemical class 0.000 claims 6
- 229910001411 inorganic cation Inorganic materials 0.000 claims 6
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 6
- 229920003176 water-insoluble polymer Polymers 0.000 claims 6
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical group [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 6
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 5
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 5
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 5
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 5
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 5
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 5
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 5
- 229920000609 methyl cellulose Polymers 0.000 claims 5
- 239000001923 methylcellulose Substances 0.000 claims 5
- 235000010981 methylcellulose Nutrition 0.000 claims 5
- 239000007864 aqueous solution Substances 0.000 claims 4
- 229920001817 Agar Polymers 0.000 claims 3
- 239000001856 Ethyl cellulose Substances 0.000 claims 3
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical group CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 3
- 229920002148 Gellan gum Polymers 0.000 claims 3
- 239000008272 agar Substances 0.000 claims 3
- 235000010419 agar Nutrition 0.000 claims 3
- 229920006318 anionic polymer Polymers 0.000 claims 3
- 229920002301 cellulose acetate Polymers 0.000 claims 3
- 229920006217 cellulose acetate butyrate Polymers 0.000 claims 3
- 235000019325 ethyl cellulose Nutrition 0.000 claims 3
- 229920001249 ethyl cellulose Polymers 0.000 claims 3
- 235000010492 gellan gum Nutrition 0.000 claims 3
- 239000000216 gellan gum Substances 0.000 claims 3
- 235000019422 polyvinyl alcohol Nutrition 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 2
- 229920000161 Locust bean gum Polymers 0.000 claims 2
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 235000010420 locust bean gum Nutrition 0.000 claims 2
- 239000000711 locust bean gum Substances 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- -1 potassium cations Chemical class 0.000 claims 2
- 235000013912 Ceratonia siliqua Nutrition 0.000 claims 1
- 240000008886 Ceratonia siliqua Species 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 230000003628 erosive effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
Landscapes
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention concerne une composition comprenant d'une part un polymère hydrosoluble de masse moléculaire élevée dont le point de trouble se situe approximativement entre 20 ·C et 90 ·C, et d'autre part un polymère de gélification. Cette composition convient comme composant d'une forme posologique pharmaceutique, et notamment la coque d'une forme posologique. Cette forme posologique convient également comme matrice comestible, c'est-à-dire directement comme forme posologique pharmaceutique.
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2002/031129 WO2003026630A1 (fr) | 2001-09-28 | 2002-09-28 | Formes dosifiees presentant un noyau interne et une couche externe de formes differentes |
| USPCT/US02/31163 | 2002-09-28 | ||
| USPCT/US02/31129 | 2002-09-28 | ||
| PCT/US2002/031024 WO2003026625A1 (fr) | 2001-09-28 | 2002-09-28 | Formes pharmaceutiques a liberation modifiee |
| USPCT/US02/31062 | 2002-09-28 | ||
| USPCT/US02/31117 | 2002-09-28 | ||
| PCT/US2002/031163 WO2003026627A1 (fr) | 2001-09-28 | 2002-09-28 | Formes pharmaceutiques composites |
| PCT/US2002/031062 WO2003026626A2 (fr) | 2001-09-28 | 2002-09-28 | Forme pharmaceutique a liberation modifiee |
| USPCT/US02/31024 | 2002-09-28 | ||
| PCT/US2002/031117 WO2003026629A2 (fr) | 2001-09-28 | 2002-09-28 | Formes de dosage a liberation modifiee |
| PCT/US2003/008960 WO2004028514A1 (fr) | 2002-09-28 | 2003-03-21 | Composition polymere et formes posologiques la comprenant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2500313A1 true CA2500313A1 (fr) | 2004-04-08 |
| CA2500313C CA2500313C (fr) | 2011-06-07 |
Family
ID=34271652
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002500311A Abandoned CA2500311A1 (fr) | 2002-09-28 | 2003-03-21 | Formes de dosage a liberation modifiee |
| CA2500313A Expired - Fee Related CA2500313C (fr) | 2002-09-28 | 2003-03-21 | Composition polymere et formes posologiques la comprenant |
| CA002500312A Abandoned CA2500312A1 (fr) | 2002-09-28 | 2003-03-21 | Forme dosifiee a liberation modifiee |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002500311A Abandoned CA2500311A1 (fr) | 2002-09-28 | 2003-03-21 | Formes de dosage a liberation modifiee |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002500312A Abandoned CA2500312A1 (fr) | 2002-09-28 | 2003-03-21 | Forme dosifiee a liberation modifiee |
Country Status (8)
| Country | Link |
|---|---|
| JP (3) | JP2006517182A (fr) |
| CN (3) | CN1700907A (fr) |
| AT (1) | ATE444739T1 (fr) |
| AU (4) | AU2003220472A1 (fr) |
| BR (5) | BR0314547A (fr) |
| CA (3) | CA2500311A1 (fr) |
| DE (2) | DE60329614D1 (fr) |
| MX (1) | MXPA05003283A (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2470463C (fr) | 2004-06-09 | 2012-09-18 | Lornamead Brands, Inc. | Produits blanchissants pour les dents et methodes de fabrication connexes |
| SA07280459B1 (ar) * | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| WO2009153635A1 (fr) * | 2008-06-19 | 2009-12-23 | University Of Witwatersrand, Johannesburg | Forme pharmaceutique chrono-thérapeutique |
| KR20130010464A (ko) * | 2010-03-23 | 2013-01-28 | 아스카 세이야쿠 가부시키가이샤 | 고형 제제 |
| EP2729180B1 (fr) * | 2011-07-08 | 2019-01-23 | The University of North Carolina At Chapel Hill | Nanoparticules de métal-bisphosphonate pour thérapie anticancéreuse et imagerie, ainsi que pour traiter des troubles des os |
| HK1203162A1 (en) * | 2012-02-07 | 2015-10-23 | 麦克内尔-Ppc股份有限公司 | Rapidly disintegrating coated tablets |
| EP2857006A4 (fr) * | 2012-06-05 | 2015-12-30 | Takeda Pharmaceutical | Comprimé à enrobage sec |
| RU2017106028A (ru) * | 2014-09-19 | 2018-10-22 | Дзе Проктер Энд Гэмбл Компани | Лекарственная форма фенилэфрина с пульсирующим высвобождением |
| AU2018390826B2 (en) | 2017-12-20 | 2024-09-12 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
| EP3731821A1 (fr) * | 2017-12-29 | 2020-11-04 | Laxxon Medical AG | Système d'administration de médicament |
| CA3226223A1 (fr) * | 2021-07-30 | 2023-02-02 | Jacob Pade Ramsoe Jacobsen | Formes posologiques a retention gastrique de 5-hydroxytryptophane |
| US12409163B2 (en) | 2021-07-30 | 2025-09-09 | Evecxia Therapeutics, Inc. | Method of enhancing 5-hydroxytryptophan (5-HTP) exposure |
| CN115295864B (zh) * | 2021-11-09 | 2023-08-11 | 深圳市德方创域新能源科技有限公司 | 正极补锂添加剂及其制备方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994007470A1 (fr) * | 1992-09-30 | 1994-04-14 | Pfizer Inc. | Article contenant un noyau et un revetement d'epaisseur non constante |
| GB9402203D0 (en) * | 1994-02-04 | 1994-03-30 | Smithkline Beecham Plc | Pharmaceutical formulation |
| DE4431653C2 (de) * | 1994-09-06 | 2000-01-20 | Lohmann Therapie Syst Lts | Manteltablette zur kontrollierten Freisetzung von Wirkstoffen, ein Verfahren zu ihrer Herstellung und ihre Verwendung |
| IT1282576B1 (it) * | 1996-02-06 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili |
| US6602521B1 (en) * | 1998-09-29 | 2003-08-05 | Impax Pharmaceuticals, Inc. | Multiplex drug delivery system suitable for oral administration |
| AU2001250646A1 (en) * | 2000-04-17 | 2001-10-30 | Yamanouchi Pharmaceutical Co..Ltd. | Drug delivery system for avoiding pharmacokinetic interaction between drugs and method thereof |
| CN1491105A (zh) * | 2001-02-13 | 2004-04-21 | 新的改进释放的制剂 |
-
2003
- 2003-03-21 BR BR0314547-6A patent/BR0314547A/pt not_active Application Discontinuation
- 2003-03-21 AU AU2003220472A patent/AU2003220472A1/en not_active Abandoned
- 2003-03-21 DE DE60329614T patent/DE60329614D1/de not_active Expired - Lifetime
- 2003-03-21 BR BR0314804-1A patent/BR0314804A/pt not_active Application Discontinuation
- 2003-03-21 AU AU2003220466A patent/AU2003220466A1/en not_active Abandoned
- 2003-03-21 BR BR0314781-9A patent/BR0314781A/pt not_active Application Discontinuation
- 2003-03-21 DE DE60335270T patent/DE60335270D1/de not_active Expired - Lifetime
- 2003-03-21 MX MXPA05003283A patent/MXPA05003283A/es unknown
- 2003-03-21 JP JP2004539769A patent/JP2006517182A/ja active Pending
- 2003-03-21 JP JP2004539770A patent/JP2006517183A/ja active Pending
- 2003-03-21 CN CN03825324.0A patent/CN1700907A/zh active Pending
- 2003-03-21 JP JP2004539767A patent/JP2006517514A/ja active Pending
- 2003-03-21 CN CN03825331.3A patent/CN1700908A/zh active Pending
- 2003-03-21 BR BR0314777-0A patent/BR0314777A/pt not_active Application Discontinuation
- 2003-03-21 AU AU2003225944A patent/AU2003225944A1/en not_active Abandoned
- 2003-03-21 CN CN03823065.8A patent/CN1684671A/zh active Pending
- 2003-03-21 CA CA002500311A patent/CA2500311A1/fr not_active Abandoned
- 2003-03-21 BR BR0314787-8A patent/BR0314787A/pt not_active IP Right Cessation
- 2003-03-21 CA CA2500313A patent/CA2500313C/fr not_active Expired - Fee Related
- 2003-03-21 AU AU2003218359A patent/AU2003218359A1/en not_active Abandoned
- 2003-03-21 CA CA002500312A patent/CA2500312A1/fr not_active Abandoned
- 2003-03-21 AT AT03714356T patent/ATE444739T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1700908A (zh) | 2005-11-23 |
| MXPA05003283A (es) | 2005-11-23 |
| BR0314787A (pt) | 2005-07-26 |
| CN1684671A (zh) | 2005-10-19 |
| AU2003225944A1 (en) | 2004-04-19 |
| AU2003218359A1 (en) | 2004-04-19 |
| CN1700907A (zh) | 2005-11-23 |
| BR0314781A (pt) | 2005-07-26 |
| ATE444739T1 (de) | 2009-10-15 |
| AU2003220472A1 (en) | 2004-04-19 |
| JP2006517514A (ja) | 2006-07-27 |
| AU2003220466A1 (en) | 2004-04-19 |
| JP2006517182A (ja) | 2006-07-20 |
| CA2500312A1 (fr) | 2004-04-08 |
| BR0314547A (pt) | 2005-08-09 |
| BR0314777A (pt) | 2005-07-26 |
| BR0314804A (pt) | 2005-08-02 |
| DE60329614D1 (de) | 2009-11-19 |
| CA2500313C (fr) | 2011-06-07 |
| JP2006517183A (ja) | 2006-07-20 |
| CA2500311A1 (fr) | 2004-04-08 |
| DE60335270D1 (de) | 2011-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2005108576A (ru) | Полимерная композиция и соднржащие ее лекарственные формы | |
| CA2500313A1 (fr) | Composition polymere et formes posologiques la comprenant | |
| AU694261B2 (en) | Modeling dough | |
| CN103601416B (zh) | 一种混凝土化学自修复微胶囊及其制备方法 | |
| JP5574369B2 (ja) | 生物活性製剤の調製方法 | |
| CA2433186A1 (fr) | Preparations pharmaceutiques a liberation retardee | |
| JP2005538105A (ja) | 水不溶性ポリマーおよび水溶性の小孔形成物質からなる2層により被覆された固体剤形の製造方法 | |
| IE882295L (en) | Controlled release formulation | |
| JPS60190725A (ja) | 薬形用水性被覆剤分散液、耐胃液性に被覆された薬形の製法および耐胃液性薬形 | |
| CN103601415B (zh) | 一种混凝土碱性调节微胶囊及其制备方法 | |
| US4931286A (en) | High gloss cellulose tablet coating | |
| CA2374020A1 (fr) | Milieu de culture simple et son procede de preparation | |
| WO2010139111A1 (fr) | Forme posologique à libération prolongée | |
| JP2002542276A5 (fr) | ||
| SE8300577L (sv) | Overdrag som tillforsekrar reglerad avgivning av akriva bestandsdelar fran biologiskt aktiva blandningar, i synnerhet farmaceutiska beredningar, jemte sett att framstella biologiskt aktiva blandningar med reglerad .... | |
| CA2390746A1 (fr) | Composition pharmaceutique a bse de derives de quinolinone et methode pour sa production | |
| HRP20190727T1 (hr) | Formulacija odgođenog otpuštanja lijeka | |
| CA2525542A1 (fr) | Composition pharmaceutique a base de beraprost sodium a effet prolonge destinee a une administration orale | |
| Osterwald | Properties of film-formers and their use in aqueous systems | |
| SI2328539T1 (en) | A smooth coating composition having a high solids content per tablet | |
| Abletshauser et al. | Film coating of pellets with insoluble polymers obtained in situ crosslinking in the fluidized bed | |
| CN104873457A (zh) | 缓释剂型 | |
| US20040228916A1 (en) | Pharmaceutical solid preparation containing a poorly soluble drug and production process thereof | |
| JPWO2018225770A1 (ja) | シームレスカプセル皮膜用組成物及びシームレスカプセル | |
| KR102149020B1 (ko) | 높은 방습성을 가지는 필름코팅정 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20190321 |