CA2564324A1 - Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes - Google Patents

Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes Download PDF

Info

Publication number: CA2564324A1
Authority: CA; Canada
Prior art keywords: around; spray; powder; dried powder; fraction
Prior art date: 2004-05-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002564324A

Other languages

English (en)

Inventor

Richard Fuhrherr

Stefan Bassarab

Karoline Bechtold-Peters

Wolfgang Friess

Patrick Garidel

Torsten Schultz-Fademrecht

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Pharma GmbH and Co KG

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-10

Filing date

2005-05-04

Publication date

2005-12-01

2005-05-04 Application filed by Individual filed Critical Individual

2005-12-01 Publication of CA2564324A1 publication Critical patent/CA2564324A1/fr

Status Abandoned legal-status Critical Current

Links

239000000843 powder Substances 0.000 title claims abstract description 536
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235000013681 dietary sucrose Nutrition 0.000 claims abstract description 46
LERPTDWHHCFIMD-BVEVKQQOSA-N (2r,3r,4s,5s,6r)-2-[(2r,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;(2r,3r,4r,5r)-2,3,5,6-tetrahydroxy-4-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanal Chemical compound O=C[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 LERPTDWHHCFIMD-BVEVKQQOSA-N 0.000 claims abstract description 34
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FVVCFHXLWDDRHG-UPLOTWCNSA-N (2s,3r,4s,5r,6r)-2-[(2r,3s,4r,5r,6r)-6-[(2s,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)[C@@H](CO)O1 FVVCFHXLWDDRHG-UPLOTWCNSA-N 0.000 claims abstract description 29
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229960003165 vancomycin Drugs 0.000 description 1
MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
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HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
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GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Microbiology (AREA)
Mycology (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Medicinal Preparation (AREA)

CA002564324A 2004-05-10 2005-05-04 Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes Abandoned CA2564324A1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE102004022926A DE102004022926A1 (de)	2004-05-10	2004-05-10	Sprühgetrocknete Pulver enthaltend zumindest ein 1,4 O-verknüpftes Saccharose-Derivat und Verfahren zu deren Herstellung
DE102004022926.0		2004-05-10
PCT/EP2005/004806 WO2005112892A1 (fr)	2004-05-10	2005-05-04	Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes

Publications (1)

Publication Number	Publication Date
CA2564324A1 true CA2564324A1 (fr)	2005-12-01

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ID=34966513

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002564324A Abandoned CA2564324A1 (fr)	2004-05-10	2005-05-04	Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes

Country Status (7)

Country	Link
EP (1)	EP1778188A1 (fr)
JP (1)	JP2007536313A (fr)
KR (1)	KR20070037441A (fr)
CA (1)	CA2564324A1 (fr)
DE (1)	DE102004022926A1 (fr)
TW (1)	TW200605917A (fr)
WO (1)	WO2005112892A1 (fr)

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US7803818B2 (en) *	2005-12-21	2010-09-28	Eisai R&D Management Co., Ltd.	Amorphous form of 1,2-dihydropyridine compound
EP2077132A1 (fr)	2008-01-02	2009-07-08	Boehringer Ingelheim Pharma GmbH & Co. KG	Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation
US20120135969A1 (en) *	2008-11-27	2012-05-31	Boehringer Ingelheim International Gmbh	Novel powdered crystalline medicines for inhalation
US10011906B2 (en)	2009-03-31	2018-07-03	Beohringer Ingelheim International Gmbh	Method for coating a surface of a component
EP3508239B1 (fr)	2009-05-18	2020-12-23	Boehringer Ingelheim International GmbH	Adaptateur, dispositif d'inhalation et pulvérisateur
JP5658268B2 (ja)	2009-11-25	2015-01-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ネブライザ
EA026241B1 (ru)	2009-11-25	2017-03-31	Бёрингер Ингельхайм Интернациональ Гмбх	Распылитель
US10016568B2 (en)	2009-11-25	2018-07-10	Boehringer Ingelheim International Gmbh	Nebulizer
JP5874724B2 (ja)	2010-06-24	2016-03-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ネブライザ
EP2694220B1 (fr)	2011-04-01	2020-05-06	Boehringer Ingelheim International GmbH	Appareil médical pourvu d'un récipient
US9827384B2 (en)	2011-05-23	2017-11-28	Boehringer Ingelheim International Gmbh	Nebulizer
WO2013152894A1 (fr)	2012-04-13	2013-10-17	Boehringer Ingelheim International Gmbh	Pulvérisateur comprenant des moyens de détrompage
ES2836977T3 (es)	2013-08-09	2021-06-28	Boehringer Ingelheim Int	Nebulizador
EP3030298B1 (fr)	2013-08-09	2017-10-11	Boehringer Ingelheim International GmbH	Nébuliseur
ES2874029T3 (es)	2014-05-07	2021-11-04	Boehringer Ingelheim Int	Nebulizador
AU2015258107B2 (en)	2014-05-07	2019-12-19	Boehringer Ingelheim International Gmbh	Nebulizer
WO2015169732A1 (fr)	2014-05-07	2015-11-12	Boehringer Ingelheim International Gmbh	Contenant, nébuliseur et utilisation
CA2965759C (fr)	2014-10-31	2023-12-12	Glaxosmithkline Intellectual Property Development Limited	Polypeptides en poudre presentant moins d'impuretes de disulfide comprenant des materiaux cationiques divalents

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JPS5012272A (fr) *	1973-06-01	1975-02-07
US5130239A (en) *	1990-03-08	1992-07-14	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Process for preparing lactosucrose high-content power
US6582728B1 (en) *	1992-07-08	2003-06-24	Inhale Therapeutic Systems, Inc.	Spray drying of macromolecules to produce inhaleable dry powders
JPH0776527A (ja) *	1993-06-28	1995-03-20	Hayashibara Biochem Lab Inc	半固形製剤とその製造方法
NZ278678A (en) *	1994-01-31	1998-03-25	Yamanouchi Pharma Co Ltd	Compressed moulded tablet with quick disintegration/dissolution in the mouth, mixture of low and high moldable saccharides as carriers
US6051256A (en) *	1994-03-07	2000-04-18	Inhale Therapeutic Systems	Dispersible macromolecule compositions and methods for their preparation and use
US5955448A (en) *	1994-08-19	1999-09-21	Quadrant Holdings Cambridge Limited	Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
US5922324A (en) *	1995-01-31	1999-07-13	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Propolis extract with improved water-solubility
US5892026A (en) *	1995-04-12	1999-04-06	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	High Trehalose content syrup
US6258341B1 (en) *	1995-04-14	2001-07-10	Inhale Therapeutic Systems, Inc.	Stable glassy state powder formulations
DE19732351A1 (de) *	1997-07-28	1999-02-04	Hoechst Ag	Verfahren zur Herstellung der Süßkraft und zur Geschmacksverbesserung einer Mischung hochintensiver Süßstoffe
US6896906B2 (en) *	2000-12-21	2005-05-24	Nektar Therapeutics	Storage stable powder compositions of interleukin-4 receptor

2004
- 2004-05-10 DE DE102004022926A patent/DE102004022926A1/de not_active Withdrawn
2005
- 2005-05-04 EP EP05738129A patent/EP1778188A1/fr not_active Withdrawn
- 2005-05-04 CA CA002564324A patent/CA2564324A1/fr not_active Abandoned
- 2005-05-04 JP JP2007512007A patent/JP2007536313A/ja active Pending
- 2005-05-04 KR KR1020067025973A patent/KR20070037441A/ko not_active Ceased
- 2005-05-04 WO PCT/EP2005/004806 patent/WO2005112892A1/fr not_active Ceased
- 2005-05-09 TW TW094114826A patent/TW200605917A/zh unknown

Cited By (1)

* Cited by examiner, † Cited by third party
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US12327457B2 (en)	2013-02-14	2025-06-10	Cfph, Llc	Games using financial indicators as random number generators

Also Published As

Publication number	Publication date
EP1778188A1 (fr)	2007-05-02
KR20070037441A (ko)	2007-04-04
JP2007536313A (ja)	2007-12-13
TW200605917A (en)	2006-02-16
DE102004022926A1 (de)	2005-12-15
WO2005112892A1 (fr)	2005-12-01

Publication	Publication Date	Title
US7723306B2 (en)	2010-05-25	Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7727962B2 (en)	2010-06-01	Powder comprising new compositions of oligosaccharides and methods for their preparation
US20050191246A1 (en)	2005-09-01	Powders comprising low molecular dextran and methods of producing those powders
CA2548132A1 (fr)	2005-06-23	Poudre contenant un dextrane de faible poids moleculaire et procede de fabrication associe
US20070298116A1 (en)	2007-12-27	Amorphous, spray-dried powders having a reduced moisture content and a high long term stability
CA2564324A1 (fr)	2005-12-01	Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes
US7611709B2 (en)	2009-11-03	1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
EP1789019B1 (fr)	2008-01-16	Poudres contenant de nouveaux melanges d'oligosaccharides et procedes de realisation associes
EP1666028B1 (fr)	2010-03-24	Compositions de poudre sèche à dispersivité ameliorée
JP2007536314A (ja)	2007-12-13	抗体又は抗体誘導体を安定化させるための１，４ｏ−結合型サッカロース誘導体
CA2654264C (fr)	2014-08-05	Poudre pour inhalation contenant de la phenylalanine
HK1092687B (en)	2010-11-19	Dry powder compositions having improved dispersivity

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Date	Code	Title	Description
2010-05-03	EEER	Examination request
2011-05-04	FZDE	Discontinued

CA2564324A1 - Poudres sechees par pulverisation contenant au moins un derive de saccharose a liaison o en 1,4 et procedes de realisation associes - Google Patents

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