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CA2385791A1 - Molecules de detection et de traitement de maladies - Google Patents

Molecules de detection et de traitement de maladies Download PDF

Info

Publication number
CA2385791A1
CA2385791A1 CA002385791A CA2385791A CA2385791A1 CA 2385791 A1 CA2385791 A1 CA 2385791A1 CA 002385791 A CA002385791 A CA 002385791A CA 2385791 A CA2385791 A CA 2385791A CA 2385791 A1 CA2385791 A1 CA 2385791A1
Authority
CA
Canada
Prior art keywords
polynucleotide
sequence
mddt
sequences
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002385791A
Other languages
English (en)
Inventor
David M. Hodgson
Stephen E. Lincoln
Frank D. Russo
Peter A. Spiro
Steven C. Banville
Shawn R. Bratcher
Gerard E. Dufour
Howard J. Cohen
Bruce H. Rosen
Purvi Shah
Michael S. Chalup
Jennifer L. Hillman
Anissa L. Jones
Jimmy Y. Yu
Lila B. Greenawalt
Scott R. Panzer
Ann M. Roseberry
Rachel J. Wright
Wensheng Chen
Tommy F. Liu
Pierre E. Yap
Theresa K. Stockdreher
Stefan Amshey
Willy T. Fong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2385791A1 publication Critical patent/CA2385791A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des polynucléotides purifiés de molécules de détection et de traitement de maladies (mddt). L'invention concerne également les polypeptides (MDDT) codés par mddt, ainsi que l'utilisation des mddt, ou des compléments, oligonucléotides ou fragments de ces derniers dans des méthodes diagnostiques. L'invention concerne en outre des vecteurs et des cellules hôtes contenant mddt pour l'expression de MDDT. L'invention concerne encore l'utilisation de MDDT isolés et purifiés afin d'induire des anticorps et de cribler des banques de composés, et l'utilisation d'anticorps anti-MDDT dans des méthodes diagnostiques. L'invention concerne par ailleurs des microéchantillons contenant mddt et des procédés d'utilisation.
CA002385791A 1999-09-28 2000-09-22 Molecules de detection et de traitement de maladies Abandoned CA2385791A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15656599P 1999-09-28 1999-09-28
US60/156,565 1999-09-28
US16819799P 1999-11-30 1999-11-30
US60/168,197 1999-11-30
PCT/US2000/026085 WO2001023538A2 (fr) 1999-09-28 2000-09-22 Molecules de detection et de traitement de maladies

Publications (1)

Publication Number Publication Date
CA2385791A1 true CA2385791A1 (fr) 2001-04-05

Family

ID=26853314

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002385791A Abandoned CA2385791A1 (fr) 1999-09-28 2000-09-22 Molecules de detection et de traitement de maladies

Country Status (4)

Country Link
EP (1) EP1222258A2 (fr)
AU (1) AU7607200A (fr)
CA (1) CA2385791A1 (fr)
WO (1) WO2001023538A2 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458939B1 (en) * 1996-03-15 2002-10-01 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
EP0948531A1 (fr) * 1996-12-11 1999-10-13 Chiron Corporation Proteines humaines secretees
WO1998056951A1 (fr) * 1997-06-11 1998-12-17 Abbott Laboratories Reactifs et procedes utiles dans la detection de maladies pulmonaires
WO1999002724A2 (fr) * 1997-07-11 1999-01-21 Mount Sinai Hospital Corporation Procede d'identification de genes exprimes dans des lignees selectionnees et nouveaux genes identifies au moyen de ces procedes
WO1999046293A1 (fr) * 1998-03-12 1999-09-16 Shanghai Second Medical University Proteine a doigt de zinc derivee de cellules hematopoietiques
WO2000000513A1 (fr) * 1998-06-29 2000-01-06 Shanghai Second Medical University Gene humain krab-np (npaawe05)

Also Published As

Publication number Publication date
WO2001023538A3 (fr) 2002-05-02
AU7607200A (en) 2001-04-30
WO2001023538A2 (fr) 2001-04-05
EP1222258A2 (fr) 2002-07-17

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Legal Events

Date Code Title Description
FZDE Discontinued