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CA2420983A1 - Molecules permettant la detection et le traitement de maladies - Google Patents

Molecules permettant la detection et le traitement de maladies Download PDF

Info

Publication number
CA2420983A1
CA2420983A1 CA002420983A CA2420983A CA2420983A1 CA 2420983 A1 CA2420983 A1 CA 2420983A1 CA 002420983 A CA002420983 A CA 002420983A CA 2420983 A CA2420983 A CA 2420983A CA 2420983 A1 CA2420983 A1 CA 2420983A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
antibody
mddt
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002420983A
Other languages
English (en)
Inventor
Stuart Jackson
Stephen E. Lincoln
Christina M. Altus
Gerard E. Dufour
Michael S. Chalup
Jennifer L. Jackson
Anissa Lee Jones
Jimmy Y. Yu
Rachel J. Wright
Darryl Gietzen
Tommy F. Liu
Pierre E. Yap
Christopher R. Dahl
Monika G. Momiyama
Diana L. Bradley
Sameer D. Rohatgi
Bernard Harris
Ann M. Roseberry Lincoln
Edward H. Gerstin, Jr.
Careyna H. Peralta
Marie H. David
Scott R. Panzer
Vincent Flores
Abel Daffo
Rakesh Marwaha
Alice J. Chen
Simon C. Chang
Alan P. Au
Rebekah R. Inman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2420983A1 publication Critical patent/CA2420983A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des polynucléotides sous forme de molécules purifiées permettant la détection et le traitement de maladies (mddt). L'invention concerne également des polypeptides (MDDT) codés par ces mddt. L'invention concerne par ailleurs l'utilisation des éléments suivants dans des épreuves diagnostiques: mddt, ou compléments, oligonucléotides, ou fragments. L'invention concerne en outre des vecteurs et des cellules hôtes renfermant des mddt, pour l'expression des MDDT. L'invention concerne enfin l'utilisation de MDDT isolés et purifiés pour l'induction d'anticorps et le criblage de librairies de composés, l'utilisation d'anticorps anti-MDDT dans des épreuves diagnostiques, ainsi que des jeux ordonnés de microéchantillons et des procédés d'utilisation correspondants.
CA002420983A 2000-09-05 2001-09-05 Molecules permettant la detection et le traitement de maladies Abandoned CA2420983A1 (fr)

Applications Claiming Priority (47)

Application Number Priority Date Filing Date Title
US22975000P 2000-09-05 2000-09-05
US23058300P 2000-09-05 2000-09-05
US22974800P 2000-09-05 2000-09-05
US22974900P 2000-09-05 2000-09-05
US22974700P 2000-09-05 2000-09-05
US22975100P 2000-09-05 2000-09-05
US60/229,747 2000-09-05
US60/229,748 2000-09-05
US60/229,750 2000-09-05
US60/229,751 2000-09-05
US60/229,749 2000-09-05
US60/230,583 2000-09-05
US23051700P 2000-09-06 2000-09-06
US23051900P 2000-09-06 2000-09-06
US23098900P 2000-09-06 2000-09-06
US23059500P 2000-09-06 2000-09-06
US23050500P 2000-09-06 2000-09-06
US23051800P 2000-09-06 2000-09-06
US23059800P 2000-09-06 2000-09-06
US23086500P 2000-09-06 2000-09-06
US23059700P 2000-09-06 2000-09-06
US23098800P 2000-09-06 2000-09-06
US23051400P 2000-09-06 2000-09-06
US23059900P 2000-09-06 2000-09-06
US23061000P 2000-09-06 2000-09-06
US23051500P 2000-09-06 2000-09-06
US60/230,598 2000-09-06
US60/230,599 2000-09-06
US60/230,610 2000-09-06
US60/230,505 2000-09-06
US60/230,989 2000-09-06
US60/230,597 2000-09-06
US60/230,518 2000-09-06
US60/230,595 2000-09-06
US60/230,515 2000-09-06
US60/230,514 2000-09-06
US60/230,865 2000-09-06
US60/230,519 2000-09-06
US60/230,517 2000-09-06
US60/230,988 2000-09-06
US23116300P 2000-09-07 2000-09-07
US23116700P 2000-09-07 2000-09-07
US23095100P 2000-09-07 2000-09-07
US60/231,163 2000-09-07
US60/230,951 2000-09-07
US60/231,167 2000-09-07
PCT/US2001/027628 WO2002040715A2 (fr) 2000-09-05 2001-09-05 Molecules permettant la detection et le traitement de maladies

Publications (1)

Publication Number Publication Date
CA2420983A1 true CA2420983A1 (fr) 2002-05-23

Family

ID=27586707

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002420983A Abandoned CA2420983A1 (fr) 2000-09-05 2001-09-05 Molecules permettant la detection et le traitement de maladies

Country Status (3)

Country Link
EP (1) EP1343885A2 (fr)
CA (1) CA2420983A1 (fr)
WO (1) WO2002040715A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078205B2 (en) 2000-02-17 2006-07-18 Millennium Pharmaceuticals, Inc. Nucleic acid sequences encoding melanoma associated antigen molecules, aminotransferase molecules, atpase molecules, acyltransferase molecules, pyridoxal-phosphate dependent enzyme molecules and uses therefor
US20020106770A1 (en) * 2000-07-20 2002-08-08 Millennium Pharmaceuticals, Inc. 25233, a novel human aminotransferase and uses therefor
US20020156259A1 (en) * 2000-08-15 2002-10-24 Conklin Darrell C. Human adenosine deaminase
US6706513B2 (en) 2000-08-21 2004-03-16 Bristol-Myers Squibb Company Adenosine deaminase homolog
WO2002024895A2 (fr) * 2000-09-22 2002-03-28 Incyte Genomics, Inc. Facteurs de transcription et protéines à doigt de zinc
AU2001297575A1 (en) * 2000-11-08 2002-10-08 Millennium Pharmaceuticals, Inc. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
AU2002249816A1 (en) * 2000-12-15 2002-07-24 Millennium Pharmaceuticals, Inc. Human sugar transporter proteins, potassium channel proteins, phospholipid transporter proteins and methods of use thereof
US6989441B2 (en) 2001-02-15 2006-01-24 Millennium Pharmaceuticals, Inc. 25466, a human transporter family member and uses therefor
EP1464651A1 (fr) * 2003-04-03 2004-10-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Protéine associée à la distrophine (Drop1) utilisée comme marqueur por le cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458939B1 (en) * 1996-03-15 2002-10-01 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
US6262249B1 (en) * 1998-06-23 2001-07-17 Chiron Corporation Pancreatic cancer genes
EP1121598A4 (fr) * 1998-10-06 2002-01-30 Univ Georgetown Detection de pleiotrophine
EP1074617A3 (fr) * 1999-07-29 2004-04-21 Research Association for Biotechnology Amorces pour la synthèse de cADN de pleine longueur et leur utilisation

Also Published As

Publication number Publication date
EP1343885A2 (fr) 2003-09-17
WO2002040715A3 (fr) 2003-07-17
WO2002040715A8 (fr) 2002-10-24
WO2002040715A2 (fr) 2002-05-23

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Legal Events

Date Code Title Description
FZDE Discontinued