CA2372980A1 - Dosages pour agonistes, antagonistes et agonistes inverses d'hormone concentrant la melanine (mch) se liant au recepteur du type somatostatine (slc-1) - Google Patents
Dosages pour agonistes, antagonistes et agonistes inverses d'hormone concentrant la melanine (mch) se liant au recepteur du type somatostatine (slc-1) Download PDFInfo
- Publication number
- CA2372980A1 CA2372980A1 CA002372980A CA2372980A CA2372980A1 CA 2372980 A1 CA2372980 A1 CA 2372980A1 CA 002372980 A CA002372980 A CA 002372980A CA 2372980 A CA2372980 A CA 2372980A CA 2372980 A1 CA2372980 A1 CA 2372980A1
- Authority
- CA
- Canada
- Prior art keywords
- mch
- test compound
- slc
- agonists
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La présente invention concerne des dosages pouvant être utilisés pour détecter les composés capables d'agir comme agonistes ou antagonistes de l'hormone concentrant la mélanine (MCH). Ces dosages reposent sur la liaison de MCH au récepteur SLC-1.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13484499P | 1999-05-19 | 1999-05-19 | |
| US60/134,844 | 1999-05-19 | ||
| US13867599P | 1999-06-14 | 1999-06-14 | |
| US60/138,675 | 1999-06-14 | ||
| PCT/SE2000/001010 WO2000070347A1 (fr) | 1999-05-19 | 2000-05-19 | Dosages pour agonistes, antagonistes et agonistes inverses d'hormone concentrant la melanine (mch) se liant au recepteur du type somatostatine (slc-1) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2372980A1 true CA2372980A1 (fr) | 2000-11-23 |
Family
ID=26832742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002372980A Abandoned CA2372980A1 (fr) | 1999-05-19 | 2000-05-19 | Dosages pour agonistes, antagonistes et agonistes inverses d'hormone concentrant la melanine (mch) se liant au recepteur du type somatostatine (slc-1) |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1183539A1 (fr) |
| AU (1) | AU5260500A (fr) |
| CA (1) | CA2372980A1 (fr) |
| WO (1) | WO2000070347A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7078187B2 (en) | 2001-04-19 | 2006-07-18 | Neurogen Corporation | Melanin concentrating hormone receptors |
| US7078484B2 (en) | 2001-04-19 | 2006-07-18 | Neurogen Corporation | Melanin concentrating hormone receptors |
| US6809104B2 (en) | 2001-05-04 | 2004-10-26 | Tularik Inc. | Fused heterocyclic compounds |
| WO2003057214A1 (fr) | 2001-12-28 | 2003-07-17 | Somatocor Pharmaceuticals, Inc. | Derives d'hydantoine presentant une affinite pour les recepteurs de la somatostatine |
| PL376659A1 (pl) | 2002-11-06 | 2006-01-09 | Tularik Inc. | Skondensowane związki heterocykliczne |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0871669A4 (fr) * | 1994-12-16 | 2000-02-09 | Smithkline Beecham Corp | Recepteur humain somatostatinoide |
| US5849708A (en) * | 1995-06-06 | 1998-12-15 | Joslin Diabetes Center, Inc. | Promotion of eating behavior |
| CN1344321A (zh) * | 1998-12-28 | 2002-04-10 | 武田药品工业株式会社 | 筛选方法 |
-
2000
- 2000-05-19 EP EP00937431A patent/EP1183539A1/fr not_active Withdrawn
- 2000-05-19 CA CA002372980A patent/CA2372980A1/fr not_active Abandoned
- 2000-05-19 WO PCT/SE2000/001010 patent/WO2000070347A1/fr not_active Ceased
- 2000-05-19 AU AU52605/00A patent/AU5260500A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000070347A1 (fr) | 2000-11-23 |
| EP1183539A1 (fr) | 2002-03-06 |
| AU5260500A (en) | 2000-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |