PL376659A1 - Skondensowane związki heterocykliczne - Google Patents
Skondensowane związki heterocykliczneInfo
- Publication number
- PL376659A1 PL376659A1 PL376659A PL37665903A PL376659A1 PL 376659 A1 PL376659 A1 PL 376659A1 PL 376659 A PL376659 A PL 376659A PL 37665903 A PL37665903 A PL 37665903A PL 376659 A1 PL376659 A1 PL 376659A1
- Authority
- PL
- Poland
- Prior art keywords
- heterocyclic compounds
- fused heterocyclic
- fused
- compounds
- heterocyclic
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42445602P | 2002-11-06 | 2002-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL376659A1 true PL376659A1 (pl) | 2006-01-09 |
Family
ID=32312811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL376659A PL376659A1 (pl) | 2002-11-06 | 2003-11-06 | Skondensowane związki heterocykliczne |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7253179B2 (pl) |
| EP (1) | EP1562943A1 (pl) |
| JP (1) | JP4547266B2 (pl) |
| KR (1) | KR20050103184A (pl) |
| CN (2) | CN101134757A (pl) |
| AU (1) | AU2003285160B2 (pl) |
| BR (1) | BR0316070A (pl) |
| CA (1) | CA2505372A1 (pl) |
| EA (1) | EA009421B1 (pl) |
| IS (1) | IS7833A (pl) |
| MX (1) | MXPA05004739A (pl) |
| NO (1) | NO20052655L (pl) |
| NZ (1) | NZ540328A (pl) |
| PL (1) | PL376659A1 (pl) |
| WO (1) | WO2004043958A1 (pl) |
| ZA (1) | ZA200503654B (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6809104B2 (en) * | 2001-05-04 | 2004-10-26 | Tularik Inc. | Fused heterocyclic compounds |
| US20070135425A1 (en) * | 2001-05-04 | 2007-06-14 | Amgen Inc. | Fused heterocyclic compounds |
| PL376659A1 (pl) * | 2002-11-06 | 2006-01-09 | Tularik Inc. | Skondensowane związki heterocykliczne |
| AU2004209505B2 (en) | 2003-02-10 | 2009-07-23 | Banyu Pharmaceutical Co., Ltd. | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient |
| DE102010025663A1 (de) * | 2010-06-30 | 2012-01-05 | Karl-Heinz Glüsenkamp | Neue beta-Aminoaldehyd-Derivate, Verfahren zu ihrer Herstellung und ihre chemische Verwendung als reaktive Intermediate |
| MX2013001612A (es) * | 2010-08-10 | 2013-07-05 | Abbvie Inc | Moduladores de trpv3 novedosos. |
| WO2012129491A1 (en) | 2011-03-24 | 2012-09-27 | Abbott Laboratories | Trpv3 modulators |
| CA2853097A1 (en) * | 2011-10-24 | 2013-05-02 | Abbvie Inc. | Novel trpv3 modulators |
| CN106588812B (zh) * | 2016-12-07 | 2019-02-22 | 烟台大学 | 一种酰氯制备2,4-二取代噻唑啉类化合物的方法 |
| HRP20250104T1 (hr) | 2019-01-14 | 2025-03-28 | Zydus Lifesciences Limited | Novi supstituirani derivati sulfonilureje |
| HUP2200222A1 (hu) | 2022-06-17 | 2023-12-28 | Richter Gedeon Nyrt | MCHR1 antagonisták a Prader-Willi szindróma kezelésére |
Family Cites Families (55)
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|---|---|---|---|---|
| US199549A (en) * | 1878-01-22 | Improvement in screw-propellers | ||
| US23085A (en) * | 1859-03-01 | chandler | ||
| US176694A (en) * | 1876-04-25 | Improvement in screw-cutting die-stocks | ||
| JPS5825980B2 (ja) * | 1976-02-12 | 1983-05-31 | ヤマサ醤油株式会社 | サイクリックヌクレオチドの定量法 |
| JPS63258474A (ja) | 1986-08-15 | 1988-10-25 | セドナ・ファ−マセウチカルズ・ビ−・ブイ | カルバゾ−ル、ジベンゾフラン又はジベンゾチオフェン基を含む化合物の水酸基誘導体を調製するための方法 |
| US5049655A (en) * | 1989-03-22 | 1991-09-17 | The Salk Institute For Biological Studies | Melanin-concentrating hormones |
| JP2906654B2 (ja) | 1989-11-28 | 1999-06-21 | 東レ株式会社 | 免疫抑制剤及びその製造方法 |
| US5401629A (en) * | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| JP3160941B2 (ja) | 1991-06-17 | 2001-04-25 | 東レ株式会社 | カルバゾール誘導体および免疫抑制剤 |
| EP0596897B1 (en) * | 1991-07-05 | 2002-03-13 | Smithkline Becham S.P.A. | Hydroisoquinoline derivatives |
| CA2124455C (en) | 1992-09-29 | 2004-09-14 | Hiroshi Nagase | Indole derivatives, process for producing the same and medicinal uses of the same |
| US5272146A (en) * | 1992-10-02 | 1993-12-21 | The United States Of America As Represented By The United States Department Of Health And Human Services | 1,2-dihydroellipticines with activity against CNS specific cancer cell lines |
| US5457208A (en) * | 1993-06-21 | 1995-10-10 | Regents Of The University Of Minnesota | Kappa opioid receptor antagonists |
| US5464841A (en) | 1993-11-08 | 1995-11-07 | Univ Minnesota | Use of delta opioid receptor antagonists to treat immunoregulatory disorders |
| US5578725A (en) | 1995-01-30 | 1996-11-26 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5849708A (en) * | 1995-06-06 | 1998-12-15 | Joslin Diabetes Center, Inc. | Promotion of eating behavior |
| EP0848060A3 (en) * | 1996-12-11 | 2000-02-02 | Smithkline Beecham Corporation | Novel human 11CB splice variant |
| EP0894799B1 (en) | 1997-01-16 | 2004-04-07 | Toray Industries, Inc. | Indolomorphinane derivatives and remedies/preventives for cerebral disorders |
| US6555339B1 (en) | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
| JP2001525178A (ja) | 1997-12-03 | 2001-12-11 | スミスクライン ビーチャム コーポレーション | ヒト11cbスプライス変異体に対するアゴニストおよびアンタゴニストの探索方法 |
| JP2002517444A (ja) | 1998-06-11 | 2002-06-18 | メルク エンド カムパニー インコーポレーテッド | メラノコルチン受容体作動薬としてのスピロピペリジン誘導体 |
| CA2342833A1 (en) | 1998-09-17 | 2000-03-23 | Incyte Pharmaceuticals, Inc. | Human gpcr proteins |
| GB9822158D0 (en) | 1998-10-09 | 1998-12-02 | Nycomed Imaging As | Compositions |
| CN1344321A (zh) | 1998-12-28 | 2002-04-10 | 武田药品工业株式会社 | 筛选方法 |
| US6221613B1 (en) | 1998-12-31 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
| WO2000049170A1 (en) | 1999-02-18 | 2000-08-24 | Smithkline Beecham Corporation | MURINE 11cby RECEPTOR |
| EP1153932A1 (en) | 1999-02-19 | 2001-11-14 | Takeda Chemical Industries, Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| EP1183539A1 (en) | 1999-05-19 | 2002-03-06 | AstraZeneca AB | Assays for agonists, agonists and inverse agonists of melanin concentrating hormone (mch) binding to the somatostatin-like receptor (slc-1) |
| AU5869100A (en) | 1999-06-08 | 2000-12-28 | Regents Of The University Of California, The | Melanin concentrating hormone receptor |
| CA2378917A1 (en) | 1999-07-14 | 2001-01-25 | Merck & Co., Inc. | Melanin-concentrating hormone receptor |
| WO2001007611A2 (en) | 1999-07-26 | 2001-02-01 | Genentech, Inc. | Novel polynucleotides and method for the use thereof |
| WO2001007606A1 (en) | 1999-07-27 | 2001-02-01 | Smithkline Beecham Plc | Axor21, a g-protein coupled receptor |
| AU7315800A (en) | 1999-09-20 | 2001-04-24 | Takeda Chemical Industries Ltd. | Mch antagonists |
| WO2001021577A2 (en) | 1999-09-20 | 2001-03-29 | Takeda Chemical Industries, Ltd. | Melanin concentrating hormone antagonist |
| US6593108B1 (en) | 1999-11-16 | 2003-07-15 | Merck & Co., Inc. | Nucleic acid molecule encoding a melanin-concentrating hormone receptor 2 polypeptide |
| JP2001226269A (ja) | 2000-02-18 | 2001-08-21 | Takeda Chem Ind Ltd | メラニン凝集ホルモン拮抗剤 |
| JP2003532388A (ja) | 2000-03-15 | 2003-11-05 | メルク エンド カムパニー インコーポレーテッド | メラニン凝集ホルモン受容体キメラおよび融合タンパク質 |
| JP2005229804A (ja) | 2000-03-24 | 2005-09-02 | Astellas Pharma Inc | 新規なメラニンコンセントレーティングホルモン受容体 |
| AU2001256733A1 (en) | 2000-05-16 | 2001-11-26 | Takeda Chemical Industries Ltd. | Melanin-concentrating hormone antagonist |
| CA2384358A1 (en) | 2000-07-05 | 2002-01-10 | Synaptic Pharmaceutical Corporation | Dna encoding a human melanin concentrating hormone receptor (mch1) and uses thereof |
| DE60143525D1 (de) | 2000-07-05 | 2011-01-05 | Takeda Pharmaceutical | Verfahren zum screenen von mhc-rezeptorantagonisten oder -agonisten |
| WO2002006245A1 (en) | 2000-07-05 | 2002-01-24 | Synaptic Pharmarceutical Corporation | Selective melanin concentrating hormone-1 (mch1) receptor antagonists and uses thereof |
| AU2001279294A1 (en) * | 2000-07-06 | 2002-01-21 | Neurogen Corporation | Melanin concentrating hormone receptor ligands |
| SK4612003A3 (en) | 2000-10-20 | 2004-06-08 | Pfizer Prod Inc | Alpha-aryl ethanolamines and their use as beta-3 adrenergic receptor agonists |
| US20030022891A1 (en) | 2000-12-01 | 2003-01-30 | Anandan Palani | MCH antagonists and their use in the treatment of obesity |
| HK1054390B (en) * | 2000-12-22 | 2006-01-06 | Schering Corporation | Piperidine mch antagonists and their use in the treatment of obesity |
| US6900329B2 (en) | 2001-03-21 | 2005-05-31 | Schering Corporation | MCH antagonists and their use in the treatment of obesity |
| IL157456A0 (en) | 2001-03-21 | 2004-03-28 | Pharmacopeia Inc Pharmacopeia | Aryl and biaryl compounds having mch modulatory activity |
| ATE460163T1 (de) * | 2001-04-12 | 2010-03-15 | Pharmacopeia Llc | Arly und diaryl piperidinderivate verwendbar als mch-hemmer |
| US6809104B2 (en) | 2001-05-04 | 2004-10-26 | Tularik Inc. | Fused heterocyclic compounds |
| US6858619B2 (en) * | 2001-05-04 | 2005-02-22 | Amgen Inc. | Fused heterocyclic compounds |
| BR0209932A (pt) | 2001-05-22 | 2004-10-13 | Neurogen Corp | Composto ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica, preparação farmacêutica embalada, métodos para modular ligação de mch a um receptor de mch e de mvc, para alterar a atividade de transdução de sinal de um receptor de mch em uma célula, para tratar uma doença ou distúrbio associado com a ativação de receptor de mch patogênico obesidade e para determinar a presença ou ausência de receptor de mch em uma amostra, e, uso de um composto |
| US6664273B2 (en) * | 2001-11-26 | 2003-12-16 | Schering Corporation | Piperidine based MCH antagonists for treatment of obesity and CNS disorders |
| JP2005532991A (ja) * | 2002-01-10 | 2005-11-04 | ニューロジェン・コーポレーション | メラニン凝集ホルモン受容体リガンド:置換2−(4−ベンジル−ピペラジン−1−イルメチル)−及び2−(4−ベンジル−ジアゼパン−1−イルメチル)−1h−ベンゾイミダゾールアナログ |
| PL376659A1 (pl) * | 2002-11-06 | 2006-01-09 | Tularik Inc. | Skondensowane związki heterocykliczne |
-
2003
- 2003-11-06 PL PL376659A patent/PL376659A1/pl not_active Application Discontinuation
- 2003-11-06 AU AU2003285160A patent/AU2003285160B2/en not_active Ceased
- 2003-11-06 EP EP03779483A patent/EP1562943A1/en not_active Withdrawn
- 2003-11-06 JP JP2004551872A patent/JP4547266B2/ja not_active Expired - Fee Related
- 2003-11-06 ZA ZA200503654A patent/ZA200503654B/en unknown
- 2003-11-06 BR BR0316070-0A patent/BR0316070A/pt not_active IP Right Cessation
- 2003-11-06 CN CNA2007101119484A patent/CN101134757A/zh active Pending
- 2003-11-06 US US10/705,173 patent/US7253179B2/en not_active Expired - Fee Related
- 2003-11-06 MX MXPA05004739A patent/MXPA05004739A/es active IP Right Grant
- 2003-11-06 EA EA200500770A patent/EA009421B1/ru not_active IP Right Cessation
- 2003-11-06 WO PCT/US2003/035543 patent/WO2004043958A1/en not_active Ceased
- 2003-11-06 NZ NZ540328A patent/NZ540328A/en unknown
- 2003-11-06 CN CNB2003801082225A patent/CN1330651C/zh not_active Expired - Fee Related
- 2003-11-06 KR KR1020057008174A patent/KR20050103184A/ko not_active Withdrawn
- 2003-11-06 CA CA002505372A patent/CA2505372A1/en not_active Abandoned
-
2005
- 2005-05-02 IS IS7833A patent/IS7833A/is unknown
- 2005-06-02 NO NO20052655A patent/NO20052655L/no not_active Application Discontinuation
-
2007
- 2007-07-26 US US11/881,805 patent/US20080058365A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101134757A (zh) | 2008-03-05 |
| AU2003285160A1 (en) | 2004-06-03 |
| EA009421B1 (ru) | 2007-12-28 |
| US20040147538A1 (en) | 2004-07-29 |
| CA2505372A1 (en) | 2004-05-27 |
| EA200500770A1 (ru) | 2005-12-29 |
| AU2003285160B2 (en) | 2009-06-04 |
| JP4547266B2 (ja) | 2010-09-22 |
| IS7833A (is) | 2005-05-02 |
| EP1562943A1 (en) | 2005-08-17 |
| JP2006508130A (ja) | 2006-03-09 |
| CN1330651C (zh) | 2007-08-08 |
| ZA200503654B (en) | 2006-09-27 |
| US7253179B2 (en) | 2007-08-07 |
| NO20052655D0 (no) | 2005-06-02 |
| KR20050103184A (ko) | 2005-10-27 |
| NZ540328A (en) | 2008-02-29 |
| MXPA05004739A (es) | 2005-08-02 |
| US20080058365A1 (en) | 2008-03-06 |
| CN1735613A (zh) | 2006-02-15 |
| NO20052655L (no) | 2005-07-26 |
| WO2004043958A1 (en) | 2004-05-27 |
| BR0316070A (pt) | 2005-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |