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CA2352043A1 - Utilisation de particules de capsides de parvovirus dans l'inhibition de la proliferation et de la migration cellulaire - Google Patents

Utilisation de particules de capsides de parvovirus dans l'inhibition de la proliferation et de la migration cellulaire Download PDF

Info

Publication number
CA2352043A1
CA2352043A1 CA002352043A CA2352043A CA2352043A1 CA 2352043 A1 CA2352043 A1 CA 2352043A1 CA 002352043 A CA002352043 A CA 002352043A CA 2352043 A CA2352043 A CA 2352043A CA 2352043 A1 CA2352043 A1 CA 2352043A1
Authority
CA
Canada
Prior art keywords
capsid
parvovirus
cells
capsids
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002352043A
Other languages
English (en)
Inventor
Kristina Broliden
Magnus Westgren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tripep AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2352043A1 publication Critical patent/CA2352043A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne la découverte de méthodes et de compositions permettant d'inhiber la croissance et/ou la migration de cellules porteuses de l'antigène P, notamment, entre autres, les cellules d'origine hématopoïétique et des cellules endothéliales. L'invention concerne, en particulier, l'utilisation de particules de capsides de parvovirus ou de fragments de protéines de capsides de parvovirus dans la fabrication de médicaments susceptibles d'être administrés à un patient dans le but d'inhiber la croissance des progéniteurs hématopoïétiques (par exemple, avant transplantation de cellules souches), la croissance des cellules endothéliales (par exemple, en tant que traitement anti-tumorigenèse ou pour empêcher la resténose ou l'accumulation de fibres après implantation d'une prothèse) ou pour empêcher les troubles impliquant la prolifération anormale de cellules porteuses de l'antigène P (par exemple, la polyglobuline essentielle).
CA002352043A 1998-11-24 1999-11-23 Utilisation de particules de capsides de parvovirus dans l'inhibition de la proliferation et de la migration cellulaire Abandoned CA2352043A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9804022A SE520177C2 (sv) 1998-11-24 1998-11-24 Användning av tomma, icke-infektiösa, rekombinanta parvoviruskapsidpartiklar, eller P-antigenblockerande delar därav, för framställning av läkemedel för ihibering av hematopoietiska stamceller
SE9804022-3 1998-11-24
PCT/IB1999/002112 WO2000030668A2 (fr) 1998-11-24 1999-11-23 Utilisation de particules de capsides de parvovirus dans l'inhibition de la proliferation et de la migration cellulaire

Publications (1)

Publication Number Publication Date
CA2352043A1 true CA2352043A1 (fr) 2000-06-02

Family

ID=20413393

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002352043A Abandoned CA2352043A1 (fr) 1998-11-24 1999-11-23 Utilisation de particules de capsides de parvovirus dans l'inhibition de la proliferation et de la migration cellulaire

Country Status (14)

Country Link
EP (1) EP1131085A2 (fr)
JP (1) JP2003516927A (fr)
KR (1) KR20010080518A (fr)
CN (1) CN1328469A (fr)
AU (1) AU2566600A (fr)
CA (1) CA2352043A1 (fr)
CZ (1) CZ20011369A3 (fr)
HU (1) HUP0104298A2 (fr)
IS (1) IS5931A (fr)
MX (1) MXPA01004949A (fr)
NO (1) NO20012534L (fr)
PL (1) PL348640A1 (fr)
SE (1) SE520177C2 (fr)
WO (1) WO2000030668A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE345352T1 (de) 2001-07-10 2006-12-15 Deutsches Krebsforsch Zusammensetzung einer parvovirus vp1- proteinvariante und eines arvovirus ns1-proteins zur induktion von zytolyse
ATE465173T1 (de) 2004-09-24 2010-05-15 Intercell Ag Verändertes vp-1capsidprotein von parvovirus b19
CN101475942B (zh) * 2008-11-28 2012-05-23 中国人民解放军第四军医大学 一种b19病毒vp1独特区基因
WO2012159006A2 (fr) * 2011-05-18 2012-11-22 University Of Florida Research Foundation, Inc. Polypeptides et vecteurs pour le ciblage de cellules exprimant her2/neu et leurs utilisations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2002839C (fr) * 1988-11-14 2000-10-10 Neal S. Young Capsides de parvovirus
NL8902301A (nl) * 1989-09-14 1991-04-02 Rijksuniversiteit Humaan parvovirus b19 eiwitten, hun produktie en hun gebruik in diagnostische assays en vaccins.

Also Published As

Publication number Publication date
MXPA01004949A (es) 2003-03-10
SE9804022L (sv) 2000-05-25
SE520177C2 (sv) 2003-06-03
NO20012534L (no) 2001-06-29
CN1328469A (zh) 2001-12-26
AU2566600A (en) 2000-06-13
WO2000030668A8 (fr) 2000-09-14
WO2000030668A2 (fr) 2000-06-02
HUP0104298A2 (hu) 2002-03-28
EP1131085A2 (fr) 2001-09-12
IS5931A (is) 2001-05-02
JP2003516927A (ja) 2003-05-20
NO20012534D0 (no) 2001-05-23
SE9804022D0 (sv) 1998-11-24
PL348640A1 (en) 2002-06-03
CZ20011369A3 (cs) 2001-10-17
KR20010080518A (ko) 2001-08-22
WO2000030668A9 (fr) 2001-04-05
WO2000030668A3 (fr) 2000-11-09

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued