CA2200336A1 - Procedes et intermediaires permettant de preparer des 3-amino-benzo(b)azepinones - Google Patents
Procedes et intermediaires permettant de preparer des 3-amino-benzo(b)azepinonesInfo
- Publication number
- CA2200336A1 CA2200336A1 CA002200336A CA2200336A CA2200336A1 CA 2200336 A1 CA2200336 A1 CA 2200336A1 CA 002200336 A CA002200336 A CA 002200336A CA 2200336 A CA2200336 A CA 2200336A CA 2200336 A1 CA2200336 A1 CA 2200336A1
- Authority
- CA
- Canada
- Prior art keywords
- amino
- azepinones
- benzo
- intermediates
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KMFHLURLRXQOAG-UHFFFAOYSA-N 3-amino-1-benzazepin-2-one Chemical class O=C1C(N)=CC=C2C=CC=CC2=N1 KMFHLURLRXQOAG-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- OCQAXYHNMWVLRH-UHFFFAOYSA-N 2,3-dibenzoyl-2,3-dihydroxybutanedioic acid Chemical class C=1C=CC=CC=1C(=O)C(O)(C(O)=O)C(O)(C(=O)O)C(=O)C1=CC=CC=C1 OCQAXYHNMWVLRH-UHFFFAOYSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002297612A CA2297612C (fr) | 1994-10-04 | 1995-09-13 | Procedes et intermediaries permettant de preparer des 3-amino-benzo(b)azepinones |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31795094A | 1994-10-04 | 1994-10-04 | |
| US08/317,950 | 1994-10-04 | ||
| PCT/IB1995/000754 WO1996010564A1 (fr) | 1994-10-04 | 1995-09-13 | Procedes et intermediaires permettant de preparer des 3-amino-benzo(b)azepinones |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002297612A Division CA2297612C (fr) | 1994-10-04 | 1995-09-13 | Procedes et intermediaries permettant de preparer des 3-amino-benzo(b)azepinones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2200336A1 true CA2200336A1 (fr) | 1996-04-11 |
| CA2200336C CA2200336C (fr) | 2001-12-11 |
Family
ID=23235968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002200336A Expired - Fee Related CA2200336C (fr) | 1994-10-04 | 1995-09-13 | Procedes et intermediaires permettant de preparer des 3-amino-benzo(b)azepinones |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5977355A (fr) |
| EP (1) | EP0785925A1 (fr) |
| JP (2) | JP3030091B2 (fr) |
| CA (1) | CA2200336C (fr) |
| FI (1) | FI971378A0 (fr) |
| MX (1) | MX9702507A (fr) |
| WO (1) | WO1996010564A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7053211B2 (en) * | 2000-12-27 | 2006-05-30 | Merck Patent Gmbh | Process for the preparation of α-aminosubstituted carboxylic acid amides |
| KR100466797B1 (ko) * | 2001-12-31 | 2005-01-24 | 한국과학기술연구원 | 벤조아제핀 유도체 및 인듐을 이용하는 그의 제조방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW213901B (fr) * | 1992-01-27 | 1993-10-01 | Pfizer | |
| US5317017A (en) * | 1992-09-30 | 1994-05-31 | Merck & Co., Inc. | N-biphenyl-3-amido substituted benzolactams stimulate growth hormone release |
| EP0730581B1 (fr) * | 1993-11-22 | 2001-10-04 | Merck & Co. Inc. | 3-acylaminobenzazepines |
-
1995
- 1995-09-13 US US08/817,857 patent/US5977355A/en not_active Expired - Fee Related
- 1995-09-13 WO PCT/IB1995/000754 patent/WO1996010564A1/fr not_active Ceased
- 1995-09-13 EP EP95929198A patent/EP0785925A1/fr not_active Withdrawn
- 1995-09-13 MX MX9702507A patent/MX9702507A/es not_active IP Right Cessation
- 1995-09-13 JP JP8511555A patent/JP3030091B2/ja not_active Expired - Lifetime
- 1995-09-13 FI FI971378A patent/FI971378A0/fi not_active Application Discontinuation
- 1995-09-13 CA CA002200336A patent/CA2200336C/fr not_active Expired - Fee Related
-
1999
- 1999-09-14 JP JP26004999A patent/JP3323462B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI971378L (fi) | 1997-04-03 |
| WO1996010564A1 (fr) | 1996-04-11 |
| JP3030091B2 (ja) | 2000-04-10 |
| US5977355A (en) | 1999-11-02 |
| JP3323462B2 (ja) | 2002-09-09 |
| EP0785925A1 (fr) | 1997-07-30 |
| JP2000119254A (ja) | 2000-04-25 |
| JPH09512033A (ja) | 1997-12-02 |
| CA2200336C (fr) | 2001-12-11 |
| FI971378A7 (fi) | 1997-04-03 |
| MX9702507A (es) | 1997-07-31 |
| FI971378A0 (fi) | 1997-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |