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CA2287254A1 - Cytokines de mammifere; reactifs et procedes connexes - Google Patents

Cytokines de mammifere; reactifs et procedes connexes Download PDF

Info

Publication number
CA2287254A1
CA2287254A1 CA002287254A CA2287254A CA2287254A1 CA 2287254 A1 CA2287254 A1 CA 2287254A1 CA 002287254 A CA002287254 A CA 002287254A CA 2287254 A CA2287254 A CA 2287254A CA 2287254 A1 CA2287254 A1 CA 2287254A1
Authority
CA
Canada
Prior art keywords
protein
seq
polypeptide
antibody
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002287254A
Other languages
English (en)
Inventor
Joseph A. Hedrick
Theodore R. Sana
J. Fernando Bazan
Robert A. Kastelein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2287254A1 publication Critical patent/CA2287254A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des acides nucléiques codant chez un mammifère (par exemple, rongeur) les protéines suivantes : IL-1.delta., IL-1.epsilon., IL-1.delta. et IL-1.epsilon. purifiées ainsi que des fragments de ces protéines. L'invention concerne aussi des anticorps polyclonaux et monoclonaux, et des procédés liés à l'utilisation des compositions considérées à des fins diagnostiques et thérapeutiques.
CA002287254A 1997-04-21 1998-04-17 Cytokines de mammifere; reactifs et procedes connexes Abandoned CA2287254A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US83762797A 1997-04-21 1997-04-21
US5511197P 1997-08-06 1997-08-06
US60/055,111 1997-08-06
US08/837,627 1997-08-06
PCT/US1998/006879 WO1998047921A1 (fr) 1997-04-21 1998-04-17 Cytokines de mammifere; reactifs et procedes connexes

Publications (1)

Publication Number Publication Date
CA2287254A1 true CA2287254A1 (fr) 1998-10-29

Family

ID=26733854

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002287254A Abandoned CA2287254A1 (fr) 1997-04-21 1998-04-17 Cytokines de mammifere; reactifs et procedes connexes

Country Status (5)

Country Link
EP (1) EP0977779A1 (fr)
JP (1) JP2002501496A (fr)
AU (1) AU7103198A (fr)
CA (1) CA2287254A1 (fr)
WO (1) WO1998047921A1 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197551B1 (en) * 1998-01-27 2001-03-06 Millennium Pharmaceuticals, Inc. Spoil-1 protein and nucleic acid molecules and uses therefor
JP3602442B2 (ja) * 1998-01-09 2004-12-15 イミュネックス・コーポレーション ＩＬ−１δのＤＮＡおよびポリペプチド
US6962904B1 (en) 1998-03-13 2005-11-08 Connective Tissue Imagineering Elastin peptide analogs and uses thereof
US6426191B1 (en) * 1998-04-03 2002-07-30 Hyseq, Inc. Assays involving an IL-1 receptor antagonist
US6541623B1 (en) * 1998-04-03 2003-04-01 Hyseq, Inc. Interleukin—1 receptor antagonist and uses thereof
US6337072B1 (en) 1998-04-03 2002-01-08 Hyseq, Inc. Interleukin-1 receptor antagonist and recombinant production thereof
US6294655B1 (en) 1998-04-03 2001-09-25 Hyseq, Inc. Anti-interleukin-1 receptor antagonist antibodies and uses thereof
IL138576A0 (en) * 1998-04-03 2001-10-31 Hyseq Inc A novel interleukin-1 receptor antagonist and uses thereof
AU5772299A (en) * 1998-08-07 2000-02-28 Millennium Pharmaceuticals, Inc. Novel molecules of the tango-93-related protein family and uses thereof
US6838290B2 (en) 1998-08-21 2005-01-04 Immunex Corporation Methods for screening compounds that affect IL-1 epsilon activity
ATE332373T1 (de) 1998-08-21 2006-07-15 Immunex Corp Menschlisches il-1 epsilon dna und polypeptide
US6949359B1 (en) 1998-08-21 2005-09-27 Immunex Corporation Human IL-1 epsilon DNA and polypeptides
WO2000020595A1 (fr) * 1998-10-08 2000-04-13 Zymogenetics, Inc. Homologues de l'interleukine-1
CA2354027A1 (fr) * 1998-12-23 2000-07-06 Genentech, Inc. Polypeptides apparentes a il-1
US7074556B2 (en) 1999-03-02 2006-07-11 Invitrogen Corporation cDNA synthesis improvements
US6339141B1 (en) 1999-05-20 2002-01-15 Hycey Inc. Interleukin-1 Hy2 materials and methods
ATE390482T1 (de) * 1999-05-20 2008-04-15 Nuvelo Inc Interleukin-1 hy2. mittel und verfahren
WO2000071583A1 (fr) * 1999-05-24 2000-11-30 Smithkline Beecham Corporation Homologue de l'interleukine 1 murine, il-1h3
NZ528967A (en) 1999-06-22 2005-03-24 Invitrogen Corp Improved primers and methods for the amplification and discrimination of nucleic acids
US6830902B1 (en) 1999-07-02 2004-12-14 Invitrogen Corporation Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
CA2378954A1 (fr) * 1999-07-16 2001-01-25 Interleukin Genetics, Inc. Gene il-1l1 et produits polypeptidiques
CA2393532A1 (fr) * 1999-12-10 2001-06-14 Frank J. Calzone Molecules de type antagoniste du recepteur d'interleukine-1 et utilisations
US6794362B1 (en) * 2000-05-30 2004-09-21 Connective Tissue Imagineering Llc Asparagine containing elastin peptide analogs
WO2001091700A2 (fr) * 2000-05-30 2001-12-06 Connective Tissue Imagineering Llc Composition et procede destine a ameliorer l'elasticite des tissus
US20030165859A1 (en) 2001-10-23 2003-09-04 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
PT1899378E (pt) * 2005-06-21 2010-01-26 Xoma Technology Ltd Anticorpos de ligação de il-1β e os seus fragmentos
PL2598526T4 (pl) * 2010-07-29 2019-05-31 Eleven Biotherapeutics Inc Agoniści i antagoniści receptora typu i chimerycznej interleukiny il-1
US20120058481A1 (en) 2010-08-20 2012-03-08 Life Technologies Corporation Quantitative Real Time PCR Assay Using FRET Dual-Labeled Primers
WO2012103240A2 (fr) * 2011-01-25 2012-08-02 Eleven Biotherapeutics, Inc. Agents de liaison à un récepteur
EP3628746B1 (fr) 2012-11-02 2025-08-27 Life Technologies Corporation Capture, détection et quantification de petit arn
EP2971095B1 (fr) 2013-03-12 2019-11-20 Life Technologies Corporation Procédés de génotypage fondés sur des indicateurs universels, et mixtures et trousses appropriés
CN107693781B (zh) 2013-03-13 2021-11-09 巴扎德制药公司 用于眼部递送的嵌合细胞因子制剂
PT3319985T (pt) 2015-07-06 2021-01-06 Immatics Biotechnologies Gmbh Novos péptidos e combinação de péptidos para uso em imunoterapia do cancro do esófago e outros cancros
GB201511792D0 (en) * 2015-07-06 2015-08-19 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers
US20170362640A1 (en) 2016-06-16 2017-12-21 Life Technologies Corporation Novel compositions, methods and kits for microorganism detection
WO2018039599A1 (fr) 2016-08-26 2018-03-01 Life Technologies Corporation Commandes d'extraction et d'amplification d'acides nucléiques et procédés d'utilisation associés
US20200340041A1 (en) 2017-11-13 2020-10-29 Life Technologies Corporation Novel compositions, methods and kits for urinary tract microorganism detection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148009B1 (ko) * 1988-05-27 1998-08-01 그래고리 비. 아보트 인터루킨-1 억제제

Also Published As

Publication number Publication date
AU7103198A (en) 1998-11-13
WO1998047921A1 (fr) 1998-10-29
EP0977779A1 (fr) 2000-02-09
WO1998047921A9 (fr) 1999-04-22
JP2002501496A (ja) 2002-01-15

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued