PL2598526T4 - Agoniści i antagoniści receptora typu i chimerycznej interleukiny il-1 - Google Patents
Agoniści i antagoniści receptora typu i chimerycznej interleukiny il-1Info
- Publication number
- PL2598526T4 PL2598526T4 PL11749612.5T PL11749612T PL2598526T4 PL 2598526 T4 PL2598526 T4 PL 2598526T4 PL 11749612 T PL11749612 T PL 11749612T PL 2598526 T4 PL2598526 T4 PL 2598526T4
- Authority
- PL
- Poland
- Prior art keywords
- agonists
- antagonists
- receptor
- type
- chimeric interleukin
- Prior art date
Links
- 108050006617 Interleukin-1 receptor Proteins 0.000 title 1
- 102000019223 Interleukin-1 receptor Human genes 0.000 title 1
- 108010063738 Interleukins Proteins 0.000 title 1
- 102000015696 Interleukins Human genes 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36879910P | 2010-07-29 | 2010-07-29 | |
| US201161436184P | 2011-01-25 | 2011-01-25 | |
| US201161436178P | 2011-01-25 | 2011-01-25 | |
| US201161493967P | 2011-06-06 | 2011-06-06 | |
| US201161493966P | 2011-06-06 | 2011-06-06 | |
| EP11749612.5A EP2598526B1 (en) | 2010-07-29 | 2011-07-29 | Chimeric il-1 receptor type i agonists and antagonists |
| PCT/US2011/045995 WO2012016203A1 (en) | 2010-07-29 | 2011-07-29 | Chimeric il-1 receptor type i agonists and antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL2598526T3 PL2598526T3 (pl) | 2019-02-28 |
| PL2598526T4 true PL2598526T4 (pl) | 2019-05-31 |
Family
ID=44533130
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11749612.5T PL2598526T4 (pl) | 2010-07-29 | 2011-07-29 | Agoniści i antagoniści receptora typu i chimerycznej interleukiny il-1 |
| PL18191564.6T PL3470421T3 (pl) | 2010-07-29 | 2011-07-29 | Chimeryczne antagonisty receptora il-1 typu i |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18191564.6T PL3470421T3 (pl) | 2010-07-29 | 2011-07-29 | Chimeryczne antagonisty receptora il-1 typu i |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8853150B2 (pl) |
| EP (3) | EP2598526B1 (pl) |
| JP (1) | JP6030554B2 (pl) |
| KR (1) | KR102080704B1 (pl) |
| CN (2) | CN103221422B (pl) |
| AU (3) | AU2011283669A1 (pl) |
| BR (1) | BR112013003646B1 (pl) |
| CA (1) | CA2806438C (pl) |
| DK (1) | DK2598526T3 (pl) |
| ES (2) | ES2701405T3 (pl) |
| HK (1) | HK1246327A1 (pl) |
| HR (2) | HRP20181446T1 (pl) |
| HU (2) | HUE063115T2 (pl) |
| IL (2) | IL224435B (pl) |
| LT (1) | LT2598526T (pl) |
| MX (1) | MX360097B (pl) |
| NZ (1) | NZ605928A (pl) |
| PL (2) | PL2598526T4 (pl) |
| RU (2) | RU2754957C2 (pl) |
| SG (1) | SG187231A1 (pl) |
| SI (1) | SI2598526T1 (pl) |
| WO (1) | WO2012016203A1 (pl) |
| ZA (1) | ZA201505145B (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0708376D0 (en) | 2007-05-01 | 2007-06-06 | Alligator Bioscience Ab | Novel polypeptides and uses thereof |
| PL2598526T4 (pl) | 2010-07-29 | 2019-05-31 | Eleven Biotherapeutics Inc | Agoniści i antagoniści receptora typu i chimerycznej interleukiny il-1 |
| WO2012103240A2 (en) * | 2011-01-25 | 2012-08-02 | Eleven Biotherapeutics, Inc. | Receptor binding agents |
| US20140341843A1 (en) * | 2011-07-29 | 2014-11-20 | Eleven Biotherapeutics, Inc. | Purified proteins |
| WO2013184938A2 (en) * | 2012-06-08 | 2013-12-12 | Alkermes. Inc. | Fusion polypeptides comprising mucin-domain polypeptide linkers |
| AU2015268652B2 (en) * | 2012-06-08 | 2017-11-23 | Mural Oncology, Inc. | Ligands modified by circular permutation as agonists and antagonists |
| CN107693781B (zh) | 2013-03-13 | 2021-11-09 | 巴扎德制药公司 | 用于眼部递送的嵌合细胞因子制剂 |
| JP2016520615A (ja) * | 2013-05-31 | 2016-07-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | アルツハイマー病を処置するためのil−1アンタゴニストを使用する方法 |
| WO2014195953A1 (en) * | 2013-06-05 | 2014-12-11 | Ben Gurion University Of The Negev Research And Develpment Authority | IL-1beta-IL-1Ra CHIMERA AND METHODS OF USING THE SAME |
| WO2015048526A1 (en) * | 2013-09-27 | 2015-04-02 | Eleven Biotherapeutics, Inc. | Treating ocular pain |
| TW201538178A (zh) | 2014-03-13 | 2015-10-16 | Eleven Biotherapeutics Inc | 生產於吹氣成型充塡密封容器內穩定的嵌合型細胞激素蛋白質配方之方法 |
| EP3871682A1 (en) * | 2016-10-14 | 2021-09-01 | i.com Medical GmbH | Method for establishing, restoring, and preserving homeostasis of the ocular surface |
| EP3781175A1 (en) | 2018-04-18 | 2021-02-24 | i.com Medical GmbH | High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease |
| WO2020157570A1 (en) | 2019-01-31 | 2020-08-06 | i.com medical GmbH | Hyaluronic acid for relief of idiopathic ocular pain |
| WO2022204267A1 (en) | 2021-03-24 | 2022-09-29 | Alkermes, Inc. | Upar antibodies and fusion proteins with the same |
| CN114480406B (zh) * | 2021-09-16 | 2024-01-30 | 广东翠点生物科技有限公司 | 一种il-1信号通路响应元件及其应用 |
| CA3245538A1 (en) | 2022-03-10 | 2023-09-14 | Buzzard Pharmaceuticals AB | INTERLEUKIN-1 TYPE 1 RECEPTOR INHIBITOR INTENDED FOR USE IN CANCER TREATMENT |
| WO2025024729A1 (en) * | 2023-07-27 | 2025-01-30 | Rush University Medical Center | Novel chitosan-il-36ra conjugates for adjustable, sustained release and tissue distribution |
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