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CA2004571A1 - Administration transdermique et intranasale de peptides inhibiteurs de la renine - Google Patents

Administration transdermique et intranasale de peptides inhibiteurs de la renine

Info

Publication number
CA2004571A1
CA2004571A1 CA002004571A CA2004571A CA2004571A1 CA 2004571 A1 CA2004571 A1 CA 2004571A1 CA 002004571 A CA002004571 A CA 002004571A CA 2004571 A CA2004571 A CA 2004571A CA 2004571 A1 CA2004571 A1 CA 2004571A1
Authority
CA
Canada
Prior art keywords
ile
phe
pro
mehis
lva
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002004571A
Other languages
English (en)
Inventor
Donald T. Pals
Lawrence S. Olanoff
Judy A. Lawson
Richard E. Gibson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CA2004571A1 publication Critical patent/CA2004571A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/553—Renin inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA002004571A 1988-12-22 1989-12-05 Administration transdermique et intranasale de peptides inhibiteurs de la renine Abandoned CA2004571A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28853188A 1988-12-22 1988-12-22
US07/288,531 1988-12-22

Publications (1)

Publication Number Publication Date
CA2004571A1 true CA2004571A1 (fr) 1990-06-22

Family

ID=23107533

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002004571A Abandoned CA2004571A1 (fr) 1988-12-22 1989-12-05 Administration transdermique et intranasale de peptides inhibiteurs de la renine

Country Status (5)

Country Link
EP (1) EP0449943A1 (fr)
JP (1) JPH04502458A (fr)
AU (1) AU4664089A (fr)
CA (1) CA2004571A1 (fr)
WO (1) WO1990006761A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19819652A1 (de) * 1998-05-02 1999-11-11 Lohmann Therapie Syst Lts Therapeutisches System zur topischen oder transmucosalen Applikation wenigstens eines Pflege- oder Wirkstoffs auf bzw. durch die Nasenschleimhaut sowie Verfahren zur Applikation des Systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0486478A3 (en) * 1984-08-06 1992-08-12 The Upjohn Company Renin-inhibiting peptides
US4906613A (en) * 1985-11-05 1990-03-06 Schering Corporation Antiglaucoma compositions and methods
US4758584A (en) * 1987-02-05 1988-07-19 Ciba-Geigy Corporation Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups

Also Published As

Publication number Publication date
JPH04502458A (ja) 1992-05-07
EP0449943A1 (fr) 1991-10-09
AU4664089A (en) 1990-07-10
WO1990006761A1 (fr) 1990-06-28

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Legal Events

Date Code Title Description
FZDE Dead