BRPI0819975A2 - Processo para redução dos efeitos da doença de enxerto contra hospedeiros com o uso de células t reguladoras cd4+cd25+ expandidas ex vivo - Google Patents

Processo para redução dos efeitos da doença de enxerto contra hospedeiros com o uso de células t reguladoras cd4+cd25+ expandidas ex vivo

Info

Publication number: BRPI0819975A2
Authority: BR; Brazil
Prior art keywords: regulatory; cells; reducing; effects; host disease
Prior art date: 2007-11-30

Application number

BRPI0819975-2A

Other languages

English (en)

Inventor

Tinghua Cao

Li Li

Original Assignee

Therakos Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-11-30

Filing date

2008-12-01

Publication date

2015-06-16

2008-12-01 Application filed by Therakos Inc filed Critical Therakos Inc

2015-06-16 Publication of BRPI0819975A2 publication Critical patent/BRPI0819975A2/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/22—Immunosuppressive or immunotolerising
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/418—Antigens related to induction of tolerance to non-self
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Transplantation (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Microbiology (AREA)
Mycology (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

BRPI0819975-2A 2007-11-30 2008-12-01 Processo para redução dos efeitos da doença de enxerto contra hospedeiros com o uso de células t reguladoras cd4+cd25+ expandidas ex vivo BRPI0819975A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US99130107P	2007-11-30	2007-11-30
US99234707P	2007-12-05	2007-12-05
PCT/US2008/085117 WO2009073599A1 (en)	2007-11-30	2008-12-01	Process for reducing effects of graft versus host disease using ex vivo expanded cd4+cd25+ regulatory t cells

Publications (1)

Publication Number	Publication Date
BRPI0819975A2 true BRPI0819975A2 (pt)	2015-06-16

Family

ID=40394411

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0819975-2A BRPI0819975A2 (pt)	2007-11-30	2008-12-01	Processo para redução dos efeitos da doença de enxerto contra hospedeiros com o uso de células t reguladoras cd4+cd25+ expandidas ex vivo

Country Status (9)

Country	Link
US (1)	US20090142317A1 (pt)
EP (1)	EP2225365A1 (pt)
JP (1)	JP2011505378A (pt)
KR (1)	KR20100094997A (pt)
CN (1)	CN101970643A (pt)
BR (1)	BRPI0819975A2 (pt)
CA (1)	CA2706458A1 (pt)
MX (1)	MX2010005863A (pt)
WO (1)	WO2009073599A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9314443B2 (en)	2011-10-12	2016-04-19	National Center For Child Health And Development	Enhancer of survival of transplanted organ
ES2675317T3 (es) *	2012-03-02	2018-07-10	The Regents Of The University Of California	Expansión de linfocitos T reguladores reactivos a aloantígeno
WO2013168876A1 (ko) *	2012-05-11	2013-11-14	가톨릭대학교 산학협력단	이식 후 면역 상태를 모니터링 하는 키트 및 이를 이용한 면역 상태의 모니터링 방법
EP2873417B1 (en)	2012-07-13	2019-03-06	SBI Pharmaceuticals Co., Ltd.	Immune tolerance inducer
WO2015014871A1 (en) *	2013-07-31	2015-02-05	INSERM (Institut National de la Santé et de la Recherche Médicale)	Methods and kits for identifying effector treg cells
CA2991077A1 (en) *	2015-07-03	2017-01-12	Inserm (Institut National De La Sante Et De La Recherche Medicale)	Methods for obtaining regulatory t cells and uses thereof
EP3216861A1 (en) *	2016-03-11	2017-09-13	Fropharm GmbH	Immunoregulatory cells and methods for their production
CN107164324B (zh) *	2017-07-17	2020-03-27	沃昕生物科技(深圳)有限公司	一种脐血Treg细胞的体外扩增方法
SG11202010958YA (en) *	2018-06-14	2020-12-30	4D Pharma Res Ltd	Compositions comprising bacterial strains
EP4041870A1 (en) *	2019-10-11	2022-08-17	Kuopio Center For Gene and Cell Therapy OY	New regulatory macrophages and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050186207A1 (en) *	2004-01-08	2005-08-25	The Regents Of The University Of California	Regulatory T cells suppress autoimmunity
EP1812563B1 (en) *	2004-10-29	2013-04-10	Benaroya Research Institute at Virginia Mason	Methods of generating antigen-specific cd4+cd25+ regulatory t cells, compositions and methods of use
US8323969B2 (en) *	2007-05-18	2012-12-04	University Of Kansas	Preparation of regulatory T cells using ICAM-1 co-stimulation

2008
- 2008-12-01 JP JP2010536216A patent/JP2011505378A/ja active Pending
- 2008-12-01 EP EP08855810A patent/EP2225365A1/en not_active Withdrawn
- 2008-12-01 BR BRPI0819975-2A patent/BRPI0819975A2/pt not_active IP Right Cessation
- 2008-12-01 WO PCT/US2008/085117 patent/WO2009073599A1/en not_active Ceased
- 2008-12-01 KR KR1020107013955A patent/KR20100094997A/ko not_active Withdrawn
- 2008-12-01 US US12/325,464 patent/US20090142317A1/en not_active Abandoned
- 2008-12-01 CN CN2008801186087A patent/CN101970643A/zh active Pending
- 2008-12-01 MX MX2010005863A patent/MX2010005863A/es unknown
- 2008-12-01 CA CA2706458A patent/CA2706458A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN101970643A (zh)	2011-02-09
WO2009073599A1 (en)	2009-06-11
MX2010005863A (es)	2010-06-23
JP2011505378A (ja)	2011-02-24
EP2225365A1 (en)	2010-09-08
US20090142317A1 (en)	2009-06-04
CA2706458A1 (en)	2009-06-11
KR20100094997A (ko)	2010-08-27

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Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A, 5A, 6A E 7A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.
2018-03-20	B15K	Others concerning applications: alteration of classification	Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: C12N 5/08; A61K 38/14. Ipc: A61K 39/00 (2006.01), A61K 38/14 (2006.01) Ipc: A61K 39/00 (2006.01), A61K 38/14 (2006.01)

Date

Code

Title

Description

2015-12-01

B08F

Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A, 6A E 7A ANUIDADES.

2016-04-05

B08K

Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

2018-03-20

B15K

Others concerning applications: alteration of classification

Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: C12N 5/08; A61K 38/14.

Ipc: A61K 39/00 (2006.01), A61K 38/14 (2006.01)