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BRPI0818762B8 - composição farmacêutica bicamada de liberação imediata e controlada contendo tramadol e acetaminofeno, e, uso de uma composição - Google Patents

composição farmacêutica bicamada de liberação imediata e controlada contendo tramadol e acetaminofeno, e, uso de uma composição

Info

Publication number
BRPI0818762B8
BRPI0818762B8 BRPI0818762A BRPI0818762A BRPI0818762B8 BR PI0818762 B8 BRPI0818762 B8 BR PI0818762B8 BR PI0818762 A BRPI0818762 A BR PI0818762A BR PI0818762 A BRPI0818762 A BR PI0818762A BR PI0818762 B8 BRPI0818762 B8 BR PI0818762B8
Authority
BR
Brazil
Prior art keywords
acetaminophen
composition
controlled release
release pharmaceutical
bilayer
Prior art date
Application number
BRPI0818762A
Other languages
English (en)
Inventor
Bichara Ali
Smith Damon
Le Garrec Dorothée
Ouajdi Patricia
Taga Samir
Gosein Shiva
Gervais Sonia
Sant Vinayak
Lemaire Vincent
Original Assignee
Chimigen Inc
Labopharm Barbados Ltd
Labopharm Europe Ltd
Labopharm Inc
Paladin Labs Barbados Inc
Paladin Labs Europe Ltd
Paladin Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimigen Inc, Labopharm Barbados Ltd, Labopharm Europe Ltd, Labopharm Inc, Paladin Labs Barbados Inc, Paladin Labs Europe Ltd, Paladin Labs Inc filed Critical Chimigen Inc
Publication of BRPI0818762A2 publication Critical patent/BRPI0818762A2/pt
Publication of BRPI0818762A8 publication Critical patent/BRPI0818762A8/pt
Publication of BRPI0818762B1 publication Critical patent/BRPI0818762B1/pt
Publication of BRPI0818762B8 publication Critical patent/BRPI0818762B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

composição de bicamada para a liberação de tramadol e acetaminofeno, uso de uma composição, e, método de tratar um mamífero em necessidade de analgesia. a invenção diz respeito a uma composição de bicamada para a liberação de acetaminofeno e tramadol em pelo menos um período de doze horas a seguir da administração inicial. uma única administração da composição de bicamada pode fornecer analgesia iniciando em menos do que meia hora depois da administração inicial com uma duração de pelo menos doze horas depois da administração inicial.
BRPI0818762A 2007-10-16 2008-10-15 composição farmacêutica bicamada de liberação imediata e controlada contendo tramadol e acetaminofeno, e, uso de uma composição BRPI0818762B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98020307P 2007-10-16 2007-10-16
US60/980203 2007-10-16
PCT/CA2008/001799 WO2009049405A1 (en) 2007-10-16 2008-10-15 Bilayer composition for the sustained release of acetaminophen and tramadol

Publications (4)

Publication Number Publication Date
BRPI0818762A2 BRPI0818762A2 (pt) 2015-04-07
BRPI0818762A8 BRPI0818762A8 (pt) 2017-09-19
BRPI0818762B1 BRPI0818762B1 (pt) 2019-07-02
BRPI0818762B8 true BRPI0818762B8 (pt) 2021-05-25

Family

ID=40566952

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0818762A BRPI0818762B8 (pt) 2007-10-16 2008-10-15 composição farmacêutica bicamada de liberação imediata e controlada contendo tramadol e acetaminofeno, e, uso de uma composição

Country Status (15)

Country Link
US (1) US8895066B2 (pt)
EP (1) EP2203166B1 (pt)
JP (1) JP5453280B2 (pt)
KR (1) KR20100069685A (pt)
CN (1) CN101827590A (pt)
AR (1) AR068891A1 (pt)
AU (1) AU2008314454A1 (pt)
BR (1) BRPI0818762B8 (pt)
CA (1) CA2678092C (pt)
CO (1) CO6270218A2 (pt)
ES (1) ES2541809T3 (pt)
MX (1) MX336494B (pt)
RU (1) RU2469718C2 (pt)
TW (1) TW200927196A (pt)
WO (1) WO2009049405A1 (pt)

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US9198861B2 (en) 2009-12-22 2015-12-01 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
US8597681B2 (en) 2009-12-22 2013-12-03 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
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US9980900B2 (en) * 2015-12-22 2018-05-29 Revogenex Ireland Ltd Intravenous administration of tramadol
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Also Published As

Publication number Publication date
BRPI0818762B1 (pt) 2019-07-02
WO2009049405A1 (en) 2009-04-23
ES2541809T3 (es) 2015-07-24
BRPI0818762A8 (pt) 2017-09-19
JP2011500607A (ja) 2011-01-06
MX2010004236A (es) 2010-09-07
TW200927196A (en) 2009-07-01
KR20100069685A (ko) 2010-06-24
AR068891A1 (es) 2009-12-16
EP2203166A4 (en) 2012-07-04
CN101827590A (zh) 2010-09-08
EP2203166B1 (en) 2015-05-06
BRPI0818762A2 (pt) 2015-04-07
AU2008314454A1 (en) 2009-04-23
CA2678092C (en) 2013-07-30
CO6270218A2 (es) 2011-04-20
RU2469718C2 (ru) 2012-12-20
JP5453280B2 (ja) 2014-03-26
MX336494B (es) 2016-01-21
US8895066B2 (en) 2014-11-25
US20090130183A1 (en) 2009-05-21
RU2010119463A (ru) 2011-11-27
CA2678092A1 (en) 2009-04-23
EP2203166A1 (en) 2010-07-07

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