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BRPI0816690A2 - derivados 1-amino-alquilciclohexano para tratamento e a prevenção da perda da audição - Google Patents

derivados 1-amino-alquilciclohexano para tratamento e a prevenção da perda da audição

Info

Publication number
BRPI0816690A2
BRPI0816690A2 BRPI0816690A BRPI0816690A BRPI0816690A2 BR PI0816690 A2 BRPI0816690 A2 BR PI0816690A2 BR PI0816690 A BRPI0816690 A BR PI0816690A BR PI0816690 A BRPI0816690 A BR PI0816690A BR PI0816690 A2 BRPI0816690 A2 BR PI0816690A2
Authority
BR
Brazil
Prior art keywords
prevention
amino
treatment
hearing loss
alkylcyclohexane derivatives
Prior art date
Application number
BRPI0816690A
Other languages
English (en)
Inventor
Hagen Krueger
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of BRPI0816690A2 publication Critical patent/BRPI0816690A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0816690A 2007-09-12 2008-09-10 derivados 1-amino-alquilciclohexano para tratamento e a prevenção da perda da audição BRPI0816690A2 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US99339607P 2007-09-12 2007-09-12
EP07253630 2007-09-12
US6702608P 2008-02-25 2008-02-25
US6693108P 2008-02-25 2008-02-25
US6708308P 2008-02-25 2008-02-25
EP08004776 2008-03-14
EP08004777 2008-03-14
EP08004778 2008-03-14
PCT/EP2008/007419 WO2009033650A1 (en) 2007-09-12 2008-09-10 1-amino-alkylcyclohexane derivatives for the treatment and prevention of hearing loss

Publications (1)

Publication Number Publication Date
BRPI0816690A2 true BRPI0816690A2 (pt) 2016-11-01

Family

ID=40451596

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0816712A BRPI0816712A2 (pt) 2007-09-12 2008-09-10 terapia de intervalo para o tratamento de tinnitus
BRPI0816690A BRPI0816690A2 (pt) 2007-09-12 2008-09-10 derivados 1-amino-alquilciclohexano para tratamento e a prevenção da perda da audição

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0816712A BRPI0816712A2 (pt) 2007-09-12 2008-09-10 terapia de intervalo para o tratamento de tinnitus

Country Status (21)

Country Link
US (6) US9498450B2 (pt)
EP (6) EP2548552B1 (pt)
JP (6) JP5612473B2 (pt)
KR (4) KR20100052559A (pt)
CN (4) CN101835469A (pt)
AR (3) AR071728A1 (pt)
AT (1) ATE532507T1 (pt)
AU (4) AU2008298015B2 (pt)
BR (2) BRPI0816712A2 (pt)
CA (4) CA2699210A1 (pt)
DK (1) DK2200600T3 (pt)
ES (5) ES2377253T3 (pt)
HR (1) HRP20120046T1 (pt)
MX (4) MX2010002735A (pt)
PL (1) PL2200600T3 (pt)
PT (1) PT2200600E (pt)
RU (1) RU2011137131A (pt)
SI (1) SI2200600T1 (pt)
TW (3) TW200922544A (pt)
WO (4) WO2009033649A1 (pt)
ZA (4) ZA201001261B (pt)

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EP2585049A1 (en) 2010-06-24 2013-05-01 Merz Pharma GmbH & Co. KGaA Neramexane multiple unit dosage form
WO2012098000A1 (en) 2011-01-20 2012-07-26 Merz Pharma Gmbh & Co. Kgaa Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss
EP2964249A1 (en) * 2013-03-06 2016-01-13 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure
EA201692164A1 (ru) * 2014-04-28 2017-03-31 Керин Фармасьютикал Ко., Лтд. Лекарственное средство для лечения пациентов с тиннитусом
EP3138559A4 (en) * 2014-04-28 2017-10-25 Kyorin Pharmaceutical Co., Ltd. Drug for treatment of tinnitus patients
NZ731751A (en) 2014-10-23 2023-07-28 Arena Pharm Inc Method of treating conditions related to the pgi2 receptor
EP3909579A1 (en) * 2015-05-18 2021-11-17 Sensorion Calcineurin inhibitors of the setron family for the treatment of hearing loss
KR101893604B1 (ko) 2015-08-27 2018-08-30 경희대학교 산학협력단 칸디다 유틸리스 추출물을 포함하는 난청의 예방 또는 치료용 조성물
CN105924362B (zh) * 2016-02-05 2018-08-17 上海龙翔生物医药开发有限公司 芳香环丙基胺类化合物、其药学上可接受的盐、其制备方法及其用途
KR102432505B1 (ko) 2017-03-01 2022-08-12 아레나 파마슈티칼스, 인크. Pgi2-수용체 효능제를 포함하는 조성물 및 그의 제조 방법
WO2019222764A1 (en) 2018-05-16 2019-11-21 Arena Pharmaceuticals, Inc. Compositions comprising pgi2-receptor agonists and processes for the preparation thereof
KR102268893B1 (ko) 2020-01-16 2021-06-24 경북대학교 산학협력단 림노트릭스 속 knua002 균주를 포함하는 난청의 예방 또는 치료용 조성물
CN111477199B (zh) * 2020-04-02 2021-11-30 北京瑞迪欧文化传播有限责任公司 一种嵌入式音乐控制系统
EP4297708A4 (en) * 2021-09-09 2024-08-28 Samsung Electronics Co., Ltd. AUDIO CONTENT DELIVERY MANAGEMENT

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WO2012098000A1 (en) * 2011-01-20 2012-07-26 Merz Pharma Gmbh & Co. Kgaa Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss

Also Published As

Publication number Publication date
US20110086916A1 (en) 2011-04-14
US20170027885A1 (en) 2017-02-02
EP2200598A1 (en) 2010-06-30
CA2699209A1 (en) 2009-03-19
WO2009033649A1 (en) 2009-03-19
MX2010002736A (es) 2010-04-01
ZA201001263B (en) 2011-07-27
JP2014221766A (ja) 2014-11-27
TW200922544A (en) 2009-06-01
JP5784189B2 (ja) 2015-09-24
AR070025A1 (es) 2010-03-10
EP2548552A2 (en) 2013-01-23
EP2203163B1 (en) 2014-08-27
PT2200600E (pt) 2012-02-17
AU2008298015A1 (en) 2009-03-19
ES2604945T3 (es) 2017-03-10
EP2548552B1 (en) 2015-11-18
BRPI0816712A2 (pt) 2016-11-08
JP2010539116A (ja) 2010-12-16
WO2009033650A1 (en) 2009-03-19
JP2014221767A (ja) 2014-11-27
JP5563461B2 (ja) 2014-07-30
ES2510565T3 (es) 2014-10-21
US9498450B2 (en) 2016-11-22
KR20100052556A (ko) 2010-05-19
JP2010539115A (ja) 2010-12-16
EP2386299B1 (en) 2016-07-13
EP2200600A1 (en) 2010-06-30
EP2200600B1 (en) 2011-11-09
CN101801365A (zh) 2010-08-11
US20150018425A1 (en) 2015-01-15
CN101801366A (zh) 2010-08-11
SI2200600T1 (sl) 2012-03-30
JP2010539118A (ja) 2010-12-16
JP5784188B2 (ja) 2015-09-24
EP2386299A2 (en) 2011-11-16
CA2699210A1 (en) 2009-03-19
ZA201001264B (en) 2011-07-27
KR20100052559A (ko) 2010-05-19
TW200918042A (en) 2009-05-01
AR071728A1 (es) 2010-07-14
EP2200599A1 (en) 2010-06-30
JP5612473B2 (ja) 2014-10-22
AR070026A1 (es) 2010-03-10
KR20100052558A (ko) 2010-05-19
AU2008298015B2 (en) 2012-03-22
ZA201001261B (en) 2011-08-31
WO2009033651A1 (en) 2009-03-19
TW200927087A (en) 2009-07-01
CN101795679A (zh) 2010-08-04
CA2699207A1 (en) 2009-03-19
EP2548552A3 (en) 2013-10-16
CA2699213A1 (en) 2009-03-19
AU2008298018B2 (en) 2012-01-19
US8877814B2 (en) 2014-11-04
AU2008298018A1 (en) 2009-03-19
JP5613053B2 (ja) 2014-10-22
AU2008298017B2 (en) 2012-03-01
US20100298441A1 (en) 2010-11-25
ES2596262T3 (es) 2017-01-05
US20110077304A1 (en) 2011-03-31
US9468610B2 (en) 2016-10-18
AU2008298017A1 (en) 2009-03-19
US20100298440A1 (en) 2010-11-25
HRP20120046T1 (hr) 2012-02-29
MX2010002733A (es) 2010-04-09
MX2010002735A (es) 2010-04-01
AU2008298018C1 (en) 2012-08-16
CN101835469A (zh) 2010-09-15
AU2008298016A1 (en) 2009-03-19
EP2200599B1 (en) 2016-08-31
ZA201001262B (en) 2011-07-27
RU2011137131A (ru) 2013-03-20
MX2010002734A (es) 2010-04-01
JP2010539117A (ja) 2010-12-16
ES2562709T3 (es) 2016-03-07
ATE532507T1 (de) 2011-11-15
PL2200600T3 (pl) 2012-04-30
EP2203163A1 (en) 2010-07-07
ES2377253T3 (es) 2012-03-23
KR20100052557A (ko) 2010-05-19
JP5563460B2 (ja) 2014-07-30
WO2009033652A1 (en) 2009-03-19
EP2386299A3 (en) 2012-05-02
AU2008298016B2 (en) 2012-02-02
DK2200600T3 (da) 2012-01-23

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Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]