BRPI0511325A - produto de análise e respectivo método de detecção - Google Patents
produto de análise e respectivo método de detecçãoInfo
- Publication number
- BRPI0511325A BRPI0511325A BRPI0511325-3A BRPI0511325A BRPI0511325A BR PI0511325 A BRPI0511325 A BR PI0511325A BR PI0511325 A BRPI0511325 A BR PI0511325A BR PI0511325 A BRPI0511325 A BR PI0511325A
- Authority
- BR
- Brazil
- Prior art keywords
- detection method
- analysis product
- biosensor
- immobilized
- profile
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000012491 analyte Substances 0.000 abstract 1
- 239000002159 nanocrystal Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000002096 quantum dot Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y20/00—Nanooptics, e.g. quantum optics or photonic crystals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
- G01N21/7746—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the waveguide coupled to a cavity resonator
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Plasma & Fusion (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Theoretical Computer Science (AREA)
- Mathematical Physics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
PRODUTO DE ANáLISE E RESPECTIVO MéTODO DE DETECçãO. é descrito um biossensor para detectar a presenpa de um produto de análise de objetivo. O biossensor é formado de partículas microsferoidais que têm tido uma parte de ligação ao produto de análise objetivo imobilizado em suas superfícies. As partes de ligação podem ser nucleotídeos; peptídios, proteínas, enzimas, anticorpos e assim por diante. Quando o produto de análise se liga à sua parte, o perfil do modo de galeria de sussurros (WGM) das partículas microsferoidais muda de tal forma que os picos de perfil sofrem um desvio para o vermelho ou azul. As partes de ligação imobilizadas podem incluir fluoróforos e similares de forma que emitem fluorescência, fosforescência, incandescência e similares. Estes fluoróforos podem tomar a forma de um nanocristal ou ponto quântico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2004902818A AU2004902818A0 (en) | 2004-05-26 | A method of detection | |
| PCT/AU2005/000748 WO2005116615A1 (en) | 2004-05-26 | 2005-05-26 | Biosensor using whispering gallery modes in microspheres |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0511325A true BRPI0511325A (pt) | 2007-12-04 |
Family
ID=35450987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0511325-3A BRPI0511325A (pt) | 2004-05-26 | 2005-05-26 | produto de análise e respectivo método de detecção |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20100227315A1 (pt) |
| EP (1) | EP1756548B1 (pt) |
| JP (2) | JP2008500518A (pt) |
| CN (1) | CN101027546B (pt) |
| BR (1) | BRPI0511325A (pt) |
| CA (1) | CA2567786C (pt) |
| ES (1) | ES2547928T3 (pt) |
| MX (1) | MXPA06013728A (pt) |
| NZ (1) | NZ551816A (pt) |
| WO (1) | WO2005116615A1 (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7486855B2 (en) | 2006-12-27 | 2009-02-03 | 3M Innovative Properties Company | Optical microresonator |
| US7512298B2 (en) | 2006-12-01 | 2009-03-31 | 3M Innovative Properties Company | Optical sensing methods |
| US7933022B2 (en) | 2006-12-01 | 2011-04-26 | 3M Innovative Properties Company | Integrated optical disk resonator |
| US7903906B2 (en) | 2006-12-01 | 2011-03-08 | 3M Innovative Properties Company | Optical sensing devices and methods |
| US7903240B2 (en) | 2006-12-01 | 2011-03-08 | 3M Innovative Properties Company | Optical sensing device |
| US7702202B2 (en) | 2006-12-01 | 2010-04-20 | 3M Innovative Properties Company | Optical microresonator |
| GB2445580A (en) * | 2007-01-11 | 2008-07-16 | Secr Defence | An encoded microsphere |
| EP2232233B1 (en) | 2007-12-31 | 2014-03-12 | Fujirebio Inc. | Clusters of microresonators for cavity mode optical sensing |
| JP2010091553A (ja) * | 2008-09-09 | 2010-04-22 | Konica Minolta Holdings Inc | 生体分子の検出方法 |
| AU2009317878B2 (en) * | 2008-11-21 | 2014-11-27 | Genera Biosystems Limited | Analyte detection assay |
| US20130105709A1 (en) | 2010-06-04 | 2013-05-02 | Michael Himmelhaus | Optical Cavity Mode Excitations in Magnetic Fluorescent Microparticles |
| US8779389B2 (en) | 2010-06-10 | 2014-07-15 | Universite Laval | Detection method based on whispering gallery modes in microspheres floating in a solution under test |
| US8493560B2 (en) * | 2010-08-09 | 2013-07-23 | Polytechnic Institute Of New York University | Plasmonic enhancement of whispering gallery mode biosensors |
| DE102012110126B3 (de) * | 2012-10-24 | 2013-11-28 | Karlsruher Institut für Technologie | Optisches Element und optisches Sensorsystem |
| CN103091340A (zh) * | 2013-02-22 | 2013-05-08 | 云南大学 | 一种微带表面回音壁模传感器 |
| DE102014104595A1 (de) * | 2014-04-01 | 2015-10-01 | Michael Himmelhaus | Verfahren und Vorrichtung zur labelfreien Detektion eines Analyten |
| CN106814185B (zh) * | 2017-01-11 | 2018-05-08 | 东南大学 | 一种基于回音壁模式微腔阵列的微流控检测芯片 |
| CN109142703B (zh) * | 2017-06-28 | 2021-07-13 | 南京理工大学 | 基于水溶性钙钛矿纳米晶的黄曲霉素m1的检测方法 |
| KR101960616B1 (ko) * | 2017-09-28 | 2019-03-21 | (주)바이오스퀘어 | 다중 양자점 기반 고감도 생체분자 검출법 |
| WO2020186268A1 (en) * | 2019-03-14 | 2020-09-17 | The Regents Of The University Of California | Stimuli-responsive compositions, imaging systems, and methods for using the same for biomedical applications |
| US12313629B2 (en) * | 2019-03-20 | 2025-05-27 | Biosquare Inc. | Standard material composition for verifying bioanalyzer and standard strip using same |
| KR20220118431A (ko) | 2019-12-09 | 2022-08-25 | 딥사이트 테크놀로지 인코퍼레이티드 | 감지 응용분야용 위스퍼링 갤러리 모드 공진기 |
| WO2021202093A1 (en) * | 2020-03-30 | 2021-10-07 | Deepsight Technology, Inc. | Optical microresonator array device for ultrasound sensing |
| CN111999270A (zh) * | 2020-06-10 | 2020-11-27 | 北京工业大学 | 一种基于回音壁模式光学微腔的外泌体检测方法 |
| EP4176253A2 (en) | 2020-07-01 | 2023-05-10 | Deepsight Technology, Inc. | Acousto-optic harmonic imaging with optical sensors |
| JP2024502033A (ja) * | 2020-12-31 | 2024-01-17 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ | 活性化・切断および計数(acc)技術を使用する核酸配列の特異的検出 |
| EP4409288A1 (en) * | 2021-10-01 | 2024-08-07 | PNP Research LLC | Optical background suppression in binding assays that employ polymeric microspheres |
| DE102022001000B3 (de) | 2022-03-16 | 2023-06-07 | FlulDect GmbH | Verfahren und Vorrichtung zur markierungsfreien Detektion eines Analyten |
| CN115060653B (zh) * | 2022-07-04 | 2025-03-21 | 东北大学 | 基于回音壁模式光学微腔奇异点的蛋白质分子浓度检测器 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200314A (en) * | 1990-03-23 | 1993-04-06 | Chiron Corporation | Polynucleotide capture assay employing in vitro amplification |
| US5117466A (en) * | 1991-04-30 | 1992-05-26 | The United States Of America As Represented By The United States Department Of Energy | Integrated fluorescence analysis system |
| US5384265A (en) * | 1993-03-26 | 1995-01-24 | Geo-Centers, Inc. | Biomolecules bound to catalytic inorganic particles, immunoassays using the same |
| US6544732B1 (en) * | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
| EP1221051A4 (en) * | 1999-10-14 | 2003-03-05 | Univ Utah Res Found | RESONANT OPTICAL CAVITIES FOR HIGH SENSITIVITY AND HIGH EFFICIENCY BIODETECTORS AND METHODS USING THE SAME |
| US6583399B1 (en) | 1999-11-22 | 2003-06-24 | California Institute Of Technology | Optical resonator microsphere sensor with altering Q-factor |
| JP2004500569A (ja) * | 2000-02-25 | 2004-01-08 | ルミネックス コーポレイション | 多重アッセイ法のための内部標準および内部対照 |
| US6507684B2 (en) | 2000-06-28 | 2003-01-14 | The Charles Stark Draper Laboratory, Inc. | Optical microcavity resonator system |
| US6490039B2 (en) * | 2000-08-08 | 2002-12-03 | California Institute Of Technology | Optical sensing based on whispering-gallery-mode microcavity |
| US6777244B2 (en) * | 2000-12-06 | 2004-08-17 | Hrl Laboratories, Llc | Compact sensor using microcavity structures |
| US6551788B1 (en) * | 2001-11-28 | 2003-04-22 | Beckman Coulter, Inc. | Particle-based ligand assay with extended dynamic range |
| JP2004083653A (ja) * | 2002-08-23 | 2004-03-18 | Sharp Corp | 発光装置ならびに蛍光体およびその製造方法 |
| WO2004038370A2 (en) * | 2002-10-22 | 2004-05-06 | Polytechnic University | Enhancing the sensitivity of a microsphere sensor |
| US7122384B2 (en) | 2002-11-06 | 2006-10-17 | E. I. Du Pont De Nemours And Company | Resonant light scattering microparticle methods |
| US7259855B2 (en) * | 2003-10-14 | 2007-08-21 | 3M Innovative Properties Company | Porous microsphere resonators |
| US7781226B2 (en) * | 2004-02-27 | 2010-08-24 | The Board Of Regents Of The University Of Texas System | Particle on membrane assay system |
| NZ554229A (en) * | 2004-12-10 | 2009-03-31 | Genera Biosystems Pty Ltd | Human papilloma virus (HPV) detection using nucleic acid probes, microbeads and fluorescent-activated cell sorter (FACS) |
| CN101730847B (zh) * | 2007-04-05 | 2015-03-18 | 分类生物系统有限公司 | 组合物及检测方法 |
-
2005
- 2005-05-26 CN CN200580020502XA patent/CN101027546B/zh not_active Expired - Fee Related
- 2005-05-26 US US11/597,484 patent/US20100227315A1/en not_active Abandoned
- 2005-05-26 ES ES05742019.2T patent/ES2547928T3/es not_active Expired - Lifetime
- 2005-05-26 EP EP05742019.2A patent/EP1756548B1/en not_active Expired - Lifetime
- 2005-05-26 CA CA2567786A patent/CA2567786C/en not_active Expired - Fee Related
- 2005-05-26 MX MXPA06013728A patent/MXPA06013728A/es active IP Right Grant
- 2005-05-26 WO PCT/AU2005/000748 patent/WO2005116615A1/en not_active Ceased
- 2005-05-26 JP JP2007513605A patent/JP2008500518A/ja active Pending
- 2005-05-26 NZ NZ551816A patent/NZ551816A/en not_active IP Right Cessation
- 2005-05-26 BR BRPI0511325-3A patent/BRPI0511325A/pt not_active IP Right Cessation
-
2012
- 2012-02-07 JP JP2012023728A patent/JP2012137490A/ja active Pending
-
2013
- 2013-02-22 US US13/774,298 patent/US9354174B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1756548A1 (en) | 2007-02-28 |
| JP2008500518A (ja) | 2008-01-10 |
| CA2567786A1 (en) | 2005-12-08 |
| CN101027546B (zh) | 2013-09-25 |
| EP1756548B1 (en) | 2015-06-24 |
| CN101027546A (zh) | 2007-08-29 |
| US20100227315A1 (en) | 2010-09-09 |
| US20130189706A1 (en) | 2013-07-25 |
| HK1101983A1 (en) | 2007-11-02 |
| CA2567786C (en) | 2015-01-27 |
| ES2547928T3 (es) | 2015-10-09 |
| JP2012137490A (ja) | 2012-07-19 |
| WO2005116615A1 (en) | 2005-12-08 |
| US9354174B2 (en) | 2016-05-31 |
| EP1756548A4 (en) | 2009-11-25 |
| NZ551816A (en) | 2010-10-29 |
| MXPA06013728A (es) | 2007-05-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 16A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2622 DE 06-04-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |