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BRPI0509139A - composição, e, método de estimulação de uma resposta imune em um indivìduo, de tratamento profilático de uma doença, de melhoramento de um sinal ou sintoma associado com uma doença, de alvejamento de um tumor, de inibição do crescimento de tumor, e de detecção de um tumor - Google Patents

composição, e, método de estimulação de uma resposta imune em um indivìduo, de tratamento profilático de uma doença, de melhoramento de um sinal ou sintoma associado com uma doença, de alvejamento de um tumor, de inibição do crescimento de tumor, e de detecção de um tumor

Info

Publication number
BRPI0509139A
BRPI0509139A BRPI0509139-0A BRPI0509139A BRPI0509139A BR PI0509139 A BRPI0509139 A BR PI0509139A BR PI0509139 A BRPI0509139 A BR PI0509139A BR PI0509139 A BRPI0509139 A BR PI0509139A
Authority
BR
Brazil
Prior art keywords
tumor
disease
stimulating
individual
immune response
Prior art date
Application number
BRPI0509139-0A
Other languages
English (en)
Inventor
William Soo Hoo
Eric R Jensen
Thomas Moll
Dennis J Carlo
Brian K Helmich
Soonpin Yei
Jayant Thatte
Original Assignee
Telos Fharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telos Fharmaceuticals Inc filed Critical Telos Fharmaceuticals Inc
Publication of BRPI0509139A publication Critical patent/BRPI0509139A/pt

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)

Abstract

COMPOSIçãO, E, MéTODOS DE ESTIMULAçãO DE UMA RESPOSTA IMUNE EM UM INDIVIDUO, DE TRATAMENTO PROFILáTICO DE UMA DOENçA, DE MELHORAMENTO DE UM SINAL OU SINTOMA ASSOCIADO COM UMA DOENçA, DE ALVEJAMENTO DE UM TUMOR, DE INIBIçãO DO CRESCIMENTO DE TUMOR, E DE DETECçãO DE UM TUMOR A invenção fornece composições contendo um antígeno e uma molécula alvejadora TIM. A invenção adicionalmente fornece um conjugado de molécula alvejadora TIM, por exemplo, uma molécula alvejadora TIM alvejada a uma porção terapêutica ou de diagnóstico. A invenção adicionalmente fornece métodos de usar tais composições. em uma forma de realização, a invenção fornece um método I de estimular uma resposta imune em um indivíduo pela administração de uma composição que compreende um antígeno e uma molécula alvejadora TIM em um veículo farmaceuticamente aceitável. Em uma outra forma de realização, a invenção fornece um método de estimular uma resposta imune em um indivíduo pela administração de um antígeno e uma molécula alvejadora TIM, que podem ser administrados juntos em uma única composição ou separadamente.
BRPI0509139-0A 2004-03-24 2005-03-22 composição, e, método de estimulação de uma resposta imune em um indivìduo, de tratamento profilático de uma doença, de melhoramento de um sinal ou sintoma associado com uma doença, de alvejamento de um tumor, de inibição do crescimento de tumor, e de detecção de um tumor BRPI0509139A (pt)

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TW200602077A (en) 2006-01-16
US20050276756A1 (en) 2005-12-15
EP1740224A2 (en) 2007-01-10
KR20070037570A (ko) 2007-04-05
CA2560941A1 (en) 2005-10-20
EA200601761A1 (ru) 2007-06-29
IL178219A0 (en) 2006-12-31
WO2005097211A2 (en) 2005-10-20
EP1740224A4 (en) 2008-07-02
WO2005097211A3 (en) 2007-03-29
MXPA06010844A (es) 2007-05-08
AU2005231685A1 (en) 2005-10-20
NO20064781L (no) 2006-12-19

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