MX2009003532A - Tratamiento de hiperbilirrubinemia infantil utilizando bajas dosis de estansoporfina. - Google Patents
Tratamiento de hiperbilirrubinemia infantil utilizando bajas dosis de estansoporfina.Info
- Publication number
- MX2009003532A MX2009003532A MX2009003532A MX2009003532A MX2009003532A MX 2009003532 A MX2009003532 A MX 2009003532A MX 2009003532 A MX2009003532 A MX 2009003532A MX 2009003532 A MX2009003532 A MX 2009003532A MX 2009003532 A MX2009003532 A MX 2009003532A
- Authority
- MX
- Mexico
- Prior art keywords
- stannsoporfin
- treatment
- low dosages
- infant hyperbilirubinemia
- hyperbilirubinemia
- Prior art date
Links
- LLDZJTIZVZFNCM-UHFFFAOYSA-J 3-[18-(2-carboxyethyl)-8,13-diethyl-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;dichlorotin(2+) Chemical compound [H+].[H+].[Cl-].[Cl-].[Sn+4].[N-]1C(C=C2C(=C(C)C(=CC=3C(=C(C)C(=C4)N=3)CC)[N-]2)CCC([O-])=O)=C(CCC([O-])=O)C(C)=C1C=C1C(C)=C(CC)C4=N1 LLDZJTIZVZFNCM-UHFFFAOYSA-J 0.000 title abstract 3
- 229950001307 stannsoporfin Drugs 0.000 title abstract 3
- 208000027119 bilirubin metabolic disease Diseases 0.000 title abstract 2
- 208000036796 hyperbilirubinemia Diseases 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describen métodos para tratar la hiperbilirrubinemia infantil utilizando estansoporfina. Los métodos de la invención permiten el tratamiento de varias poblaciones de pacientes con dosis de estansoporfina más bajas que las previamente consideradas como efectivas, proporcionando ventajas en la administración terapéutica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84950906P | 2006-10-04 | 2006-10-04 | |
| PCT/US2007/021486 WO2008045378A2 (en) | 2006-10-04 | 2007-10-04 | Treatment of infant hyperbilirubinemia using low dosages of stannsoporfin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009003532A true MX2009003532A (es) | 2009-06-26 |
Family
ID=39036883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009003532A MX2009003532A (es) | 2006-10-04 | 2007-10-04 | Tratamiento de hiperbilirrubinemia infantil utilizando bajas dosis de estansoporfina. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080113955A1 (es) |
| EP (1) | EP2076273A2 (es) |
| JP (1) | JP2010505854A (es) |
| KR (1) | KR20090079916A (es) |
| CN (1) | CN101631554A (es) |
| AU (1) | AU2007307112A1 (es) |
| BR (1) | BRPI0717774A2 (es) |
| CA (1) | CA2664934A1 (es) |
| EA (1) | EA200970345A1 (es) |
| IL (1) | IL197839A0 (es) |
| MX (1) | MX2009003532A (es) |
| NO (1) | NO20091580L (es) |
| WO (1) | WO2008045378A2 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7375216B2 (en) | 2002-06-04 | 2008-05-20 | Infacare Pharmaceutical Corporation | Preparation of metal mesoporphyrin compounds |
| US20060222668A1 (en) * | 2005-04-01 | 2006-10-05 | Wellspring Pharmaceutical Corporation | Stannsoporfin compositions, drug products and methods of manufacture |
| EA019864B1 (ru) | 2006-10-04 | 2014-06-30 | Инфакэар Фармасьютикал Корпорейшн | Крупномасштабное производство станнсопорфина высокой чистоты |
| US20090293326A1 (en) * | 2008-05-29 | 2009-12-03 | Bedford Nieves-Cruz | Hyperbilirubinemia management calendar |
| RU2414879C2 (ru) * | 2009-01-11 | 2011-03-27 | Николай Федосеевич Давыдкин | Способ лечения гипербилирубинемии новорожденных |
| RU2389499C1 (ru) * | 2009-02-10 | 2010-05-20 | Иван Ильич Таранов | Способ лечения больных с гипербилирубинемией |
| EP2691398B1 (en) | 2011-03-30 | 2016-09-28 | InfaCare Pharmaceutical Corporation | Methods for synthesizing metal mesoporphyrins |
| KR20140107355A (ko) * | 2011-12-01 | 2014-09-04 | 인파케어 파마슈티칼 코포레이션 | 스탠소포르핀을 이용한 고빌리루빈혈증의 치료 방법들 |
| US20200001109A1 (en) * | 2016-05-12 | 2020-01-02 | Infacare Pharmaceutical Corporation | Methods For Treating Hyperbilirubinemia With Stannsoporfin And Phototherapy |
| WO2021126855A1 (en) * | 2019-12-16 | 2021-06-24 | Mallinckrodt Hospital Products IP Unlimited Company | Methods for treating progressive hyperbilirubinemia |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4708964A (en) * | 1984-02-09 | 1987-11-24 | Chemex Pharmaceuticals | Lipoxygenase inhibitors |
| US4861876A (en) * | 1986-11-26 | 1989-08-29 | Wayne State University | Hematoporphyrin derivative and method of preparation and purification |
| US4900871A (en) * | 1987-01-02 | 1990-02-13 | Sun Refining And Marketing Company | Hydrocarbon oxidations catalyzed by iron coordination complexes containing a halogenated ligand |
| US5990363A (en) * | 1987-01-02 | 1999-11-23 | Sun Company, Inc. | Method for oxidizing alkanes using novel porphyrins synthesized from dipyrromethanes and aldehydes |
| US5062775A (en) * | 1989-09-29 | 1991-11-05 | Rocky Mountain Research, Inc. | Roller pump in an extra corporeal support system |
| US5192757A (en) * | 1990-12-20 | 1993-03-09 | Glaxo Inc. | Cobalt porphyrins |
| US5493017A (en) * | 1992-08-14 | 1996-02-20 | The Trustees Of The University Of Pennsylvania | Ring-metalated porphyrins |
| US5817830A (en) * | 1992-08-14 | 1998-10-06 | Trustees Of The University Of Pennsylvania | Pyrrolic compounds |
| US5371199B1 (en) * | 1992-08-14 | 1995-12-26 | Univ Pennsylvania | Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor |
| AU7103594A (en) * | 1993-06-14 | 1995-01-03 | Rockefeller University, The | Treatment of neonatal hyperbilirubin with metalloporphyrin |
| CA2130853A1 (en) * | 1994-08-25 | 1996-02-26 | Svetlana Kudrevich | Process for the syntheses of monosulphonated phthalocyanines, naphthobenzoporphyrazines and porphyrins via a modified meerwein reaction |
| US5912341A (en) * | 1995-03-14 | 1999-06-15 | Hoffman/Barrett, L.L.C. | Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom |
| WO1997005152A1 (en) * | 1995-08-02 | 1997-02-13 | Warner-Lambert Company | Amino acid complexes of cobalt (iii) mesoporphyrin ix and cobalt (iii) protoporphyrin ix |
| US5883246A (en) * | 1996-03-07 | 1999-03-16 | Qlt Phototherapeutics, Inc. | Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds |
| US6004530A (en) * | 1996-06-04 | 1999-12-21 | Roche Diagnostics Gmbh | Use of metallo-porphyrin conjugates for the detection of biological substances |
| GB9616353D0 (en) * | 1996-08-03 | 1996-09-11 | Secr Defence | Metallo-porphyrins |
| US6124452A (en) * | 1997-12-19 | 2000-09-26 | University Of Nebraska-Lincoln | Octafluoro-meso-tetraarylporphyrins and methods for making these compounds |
| DE19706490C1 (de) * | 1997-02-19 | 1998-09-17 | Deutsches Krebsforsch | Verfahren zur Herstellung von Säureamiden und zur Metallierung von Verbindungen und Verwendung der nach den Verfahren hergestellten Verbindungen |
| US5886173A (en) * | 1997-07-30 | 1999-03-23 | Pharmacyclics, Inc. | Metallation of macrocycles with 2,4-dicarbonyl-metal complexes |
| US6194566B1 (en) * | 1997-12-02 | 2001-02-27 | Schering Aktiengesellschaft | Process for the production of metalloporphyrin-metal complex conjugates |
| JP3673888B2 (ja) * | 1998-03-09 | 2005-07-20 | 独立行政法人科学技術振興機構 | ポルフィリン類金属錯体の製造方法 |
| DE19831217A1 (de) * | 1998-07-03 | 2000-01-05 | Schering Ag | Neue Porphyrinderivate, diese enthaltende pharmazeutische Mittel und ihre Verwendung in der photodynamischen Therapie und MRI-Diagnostik |
| US5973141A (en) * | 1998-11-27 | 1999-10-26 | Miravant Pharmaceuticals, Inc. | Method for the demethoxycarbonylation of porphyrinic compounds such as pheophorbides |
| US6462192B2 (en) * | 2001-01-23 | 2002-10-08 | Miravant Pharmaceuticals, Inc. | Processes for large scale production of tetrapyrroles |
| EP1401430A4 (en) * | 2001-05-31 | 2005-10-19 | Miravant Pharm Inc | SUBSTITUTED PORPHYRIN AND AZAPORPHYRIN DERIVATIVES AND USE IN PHOTODYNAMIC THERAPY, RADIOIMAGING, AND MRI DIAGNOSIS |
| US6818763B2 (en) * | 2002-06-04 | 2004-11-16 | Wellspring Pharmaceutical Corporation | Preparation of metal mesoporphyrin halide compounds |
| US7375216B2 (en) * | 2002-06-04 | 2008-05-20 | Infacare Pharmaceutical Corporation | Preparation of metal mesoporphyrin compounds |
| US20040097481A1 (en) * | 2002-11-20 | 2004-05-20 | Benjamin Levinson | Water-soluble mesoporphyrin compounds and methods of preparation |
| US20060222668A1 (en) * | 2005-04-01 | 2006-10-05 | Wellspring Pharmaceutical Corporation | Stannsoporfin compositions, drug products and methods of manufacture |
-
2007
- 2007-10-04 WO PCT/US2007/021486 patent/WO2008045378A2/en not_active Ceased
- 2007-10-04 MX MX2009003532A patent/MX2009003532A/es not_active Application Discontinuation
- 2007-10-04 BR BRPI0717774-7A2A patent/BRPI0717774A2/pt not_active IP Right Cessation
- 2007-10-04 JP JP2009531483A patent/JP2010505854A/ja active Pending
- 2007-10-04 US US11/867,581 patent/US20080113955A1/en not_active Abandoned
- 2007-10-04 CA CA002664934A patent/CA2664934A1/en not_active Abandoned
- 2007-10-04 AU AU2007307112A patent/AU2007307112A1/en not_active Abandoned
- 2007-10-04 KR KR1020097009043A patent/KR20090079916A/ko not_active Ceased
- 2007-10-04 EP EP07839342A patent/EP2076273A2/en not_active Withdrawn
- 2007-10-04 CN CN200780037064A patent/CN101631554A/zh active Pending
- 2007-10-04 EA EA200970345A patent/EA200970345A1/ru unknown
-
2009
- 2009-03-26 IL IL197839A patent/IL197839A0/en unknown
- 2009-04-21 NO NO20091580A patent/NO20091580L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101631554A (zh) | 2010-01-20 |
| EA200970345A1 (ru) | 2009-10-30 |
| NO20091580L (no) | 2009-05-04 |
| KR20090079916A (ko) | 2009-07-22 |
| BRPI0717774A2 (pt) | 2014-04-29 |
| AU2007307112A1 (en) | 2008-04-17 |
| JP2010505854A (ja) | 2010-02-25 |
| EP2076273A2 (en) | 2009-07-08 |
| CA2664934A1 (en) | 2008-04-17 |
| WO2008045378A2 (en) | 2008-04-17 |
| WO2008045378A3 (en) | 2008-06-05 |
| US20080113955A1 (en) | 2008-05-15 |
| IL197839A0 (en) | 2009-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |