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BR9811849A - Regiões de fixação com a matriz - Google Patents

Regiões de fixação com a matriz

Info

Publication number
BR9811849A
BR9811849A BR9811849-8A BR9811849A BR9811849A BR 9811849 A BR9811849 A BR 9811849A BR 9811849 A BR9811849 A BR 9811849A BR 9811849 A BR9811849 A BR 9811849A
Authority
BR
Brazil
Prior art keywords
matrix
fixing regions
regions
attachment regions
fixing
Prior art date
Application number
BR9811849-8A
Other languages
English (en)
Inventor
Susan Margaret Michalowski
Steven L Spiker
Original Assignee
Univ North Carolina State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina State filed Critical Univ North Carolina State
Publication of BR9811849A publication Critical patent/BR9811849A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/822—Reducing position variability, e.g. by the use of scaffold attachment region/matrix attachment region (SAR/MAR); Use of SAR/MAR to regulate gene expression

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>"REGIõES DE FIXAçãO COM A MATRIZ"<D>. Estão descritas regiões de fixação com a matriz isoladas a partir de vegetais superiores e de estruturas de DNA e vetores contendo tais regiões de fixação com a matriz. é provido um método para a identificação das regiões de fixação com a matriz.
BR9811849-8A 1997-08-06 1998-08-05 Regiões de fixação com a matriz BR9811849A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6611897P 1997-08-06 1997-08-06
PCT/US1998/016344 WO1999007866A1 (en) 1997-08-06 1998-08-05 Matrix attachment regions

Publications (1)

Publication Number Publication Date
BR9811849A true BR9811849A (pt) 2000-08-08

Family

ID=22067358

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811849-8A BR9811849A (pt) 1997-08-06 1998-08-05 Regiões de fixação com a matriz

Country Status (8)

Country Link
US (2) US6245974B1 (pt)
EP (1) EP1005560A1 (pt)
JP (1) JP2001520861A (pt)
AR (1) AR013400A1 (pt)
AU (1) AU749014B2 (pt)
BR (1) BR9811849A (pt)
CA (1) CA2298052A1 (pt)
WO (1) WO1999007866A1 (pt)

Families Citing this family (33)

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DE19848017A1 (de) * 1998-10-17 2000-04-20 Multigene Biotech Gmbh Episomal replizierender Vektor zur Expression eines Transgens in Säugerzellen
DE19942149A1 (de) * 1999-09-03 2001-03-15 Daniele Zink Verfahren zur Expression von exogenen Sequenzen in Säugerzellen
KR100408844B1 (ko) 2000-07-29 2003-12-06 한국산업기술평가원 동물세포 발현벡터
ATE437233T1 (de) 2001-01-26 2009-08-15 Selexis Sa Matrix-anheftungsregionen und verfahren zu deren verwendung
US6933136B2 (en) 2002-09-20 2005-08-23 Novo Nordisk A/S Method for making recombinant proteins
EP2298898B1 (en) * 2003-10-24 2012-12-26 Selexis S.A. High efficiency gene transfer and expression in mammalian cells by a multiple transfection procedure of matrix attachment region sequences
US8086519B2 (en) 2004-10-14 2011-12-27 Cfph, Llc System and method for facilitating a wireless financial transaction
DE602006014942D1 (de) * 2005-03-04 2010-07-29 Celltrion Inc Expressionsvektor für tierische zelle mit wenigstens einer kopie von mar-dna-sequenzen am 3'-ende des transkriptionsterminationsbereichs eines gens sowie verfahren zur expression eines fremdgens unter verwendung des vektors
US9204599B2 (en) 2009-08-19 2015-12-08 Dow Agrosciences Llc Detection of AAD1 event DAS-40278-9
RU2577143C2 (ru) * 2009-08-19 2016-03-10 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Детекция aad-1 объекта das-40278-9
JP6261863B2 (ja) * 2009-11-24 2018-01-17 ダウ アグロサイエンシィズ エルエルシー Ａａｄ−１２イベント４１６、関連するトランスジェニックダイズ系統、およびそのイベント特異的な同定
UA118332C2 (uk) 2011-09-22 2019-01-10 Емджен Інк. Білок, що зв'язує антиген cd27l
AR091069A1 (es) 2012-05-18 2014-12-30 Amgen Inc Proteinas de union a antigeno dirigidas contra el receptor st2
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
US9580486B2 (en) 2013-03-14 2017-02-28 Amgen Inc. Interleukin-2 muteins for the expansion of T-regulatory cells
US9708375B2 (en) 2013-03-15 2017-07-18 Amgen Inc. Inhibitory polypeptides specific to WNT inhibitors
KR101882366B1 (ko) 2013-05-30 2018-07-30 키닉사 파마슈티컬스, 리미티드 온코스타틴 m 수용체 항원 결합 단백질
JP6668241B2 (ja) 2013-09-05 2020-03-18 アムジエン・インコーポレーテツド 予測可能で、一貫性のある、且つ再現可能な糖型特性を示すＦｃ含有分子
MY188430A (en) 2015-04-10 2021-12-08 Amgen Inc Interleukin-2 muteins for the expansion of t-regulatory cells
CN116063543A (zh) 2015-04-24 2023-05-05 豪夫迈·罗氏有限公司 多特异性抗原结合蛋白
US11591382B2 (en) 2015-09-22 2023-02-28 Genentech, Inc. Expression of Fc-containing proteins
PL3359576T3 (pl) 2015-10-08 2025-04-14 Zymeworks Bc Inc. Konstrukty polipeptydowe wiążące antygen zawierające łańcuchy lekkie kappa i lambda oraz ich zastosowania
CN105331630A (zh) * 2015-10-29 2016-02-17 中国农业大学 一种增强玉米外源基因表达的方法
ES2875274T3 (es) 2015-11-02 2021-11-10 Hoffmann La Roche Procedimientos de preparación de formas fucosiladas y afucosiladas de una proteína
KR20250133490A (ko) 2016-05-04 2025-09-05 암젠 인크 T-조절 세포의 증식을 위한 인터류킨-2 뮤테인
EP3488002B1 (en) * 2016-07-22 2021-03-31 Oregon Health & Science University Single cell whole genome libraries and combinatorial indexing methods of making thereof
US11981891B2 (en) 2018-05-17 2024-05-14 Illumina, Inc. High-throughput single-cell sequencing with reduced amplification bias
PE20220706A1 (es) 2019-08-13 2022-05-04 Amgen Inc Muteinas de interleucina-2 para la expansion de celulas t reguladoras
CR20220341A (es) 2019-12-17 2022-08-19 Amgen Inc Agonista doble de interleucina-2/receptor de tnf para uso en terapia
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
EP4222167A1 (en) 2020-09-30 2023-08-09 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
WO2025006529A1 (en) 2023-06-27 2025-01-02 Amgen Inc. Charge pair mutations to enable correct heavy-light chain pairing

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU673859B2 (en) 1992-10-05 1996-11-28 North Carolina State University Method for increasing expression and reducing expression variability of foreign genes in plant cells
US6040185A (en) * 1993-04-19 2000-03-21 Novartis Ag Genetic stabilizing elements
US5773695A (en) 1996-01-26 1998-06-30 North Carolina State University Plant nuclear scaffold attachment region and method for increasing gene expression in transgenic cells

Also Published As

Publication number Publication date
AU749014B2 (en) 2002-06-13
JP2001520861A (ja) 2001-11-06
CA2298052A1 (en) 1999-02-18
AR013400A1 (es) 2000-12-27
AU8693698A (en) 1999-03-01
EP1005560A1 (en) 2000-06-07
US20020073448A1 (en) 2002-06-13
WO1999007866A1 (en) 1999-02-18
US6245974B1 (en) 2001-06-12

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007.