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BR9809453A - Composição de suprimento de medicamento para a liberação controlada de um ingrediente ativo dentro do meio-ambiente do estÈmago, uso da mesma, formulação farmacêutica, processo para obter gastrorretenção, para o tratamento ou profilaxia de uma doença, para melhorar a absorção gastrointestinal de medicamentos, e para a preparação de uma composição, e, estojo de partes para uso no tratamento de infecção por h. pylori. - Google Patents

Composição de suprimento de medicamento para a liberação controlada de um ingrediente ativo dentro do meio-ambiente do estÈmago, uso da mesma, formulação farmacêutica, processo para obter gastrorretenção, para o tratamento ou profilaxia de uma doença, para melhorar a absorção gastrointestinal de medicamentos, e para a preparação de uma composição, e, estojo de partes para uso no tratamento de infecção por h. pylori.

Info

Publication number
BR9809453A
BR9809453A BR9809453-0A BR9809453A BR9809453A BR 9809453 A BR9809453 A BR 9809453A BR 9809453 A BR9809453 A BR 9809453A BR 9809453 A BR9809453 A BR 9809453A
Authority
BR
Brazil
Prior art keywords
composition
treatment
active ingredient
controlled release
preparation
Prior art date
Application number
BR9809453-0A
Other languages
English (en)
Inventor
Lisbeth Illum
He Ping
Original Assignee
West Pharm Serv Drug Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharm Serv Drug Res Ltd filed Critical West Pharm Serv Drug Res Ltd
Publication of BR9809453A publication Critical patent/BR9809453A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"COMPOSIçãO DE SUPRIMENTO DE MEDICAMENTO PARA A LIBERAçãO CONTROLADA DE UM INGREDIENTE ATIVO DENTRO DO MEIO-AMBIENTE DO ESTÈMAGO, USO DA MESMA, FORMULAçãO FARMACêUTICA, PROCESSOS PARA OBTER GASTRORRETENçãO, PARA O TRATAMENTO OU PROFILAXIA DE UMA DOENçA, PARA MELHORAR A ABSORçãO GASTROINTESTINAL DE MEDICAMENTOS, E PARA A PREPARAçãO DE UMA COMPOSIçãO, E, ESTOJO DE PARTES PARA USO NO TRATAMENTO DE INFECçãO POR H. PYLORI" é fornecida uma composição de sumprimento de medicamento, para a liberação controlada de um agente ativo no meio-ambiente estomacal, durante um período prolongado de tempo, que compreende uma microesfera consistindo de um ingrediente ativo no núcleo interno da microesfera, (i) uma camada de controle de taxa de um polímero insolúvel em água e (ii) uma camada externa de um agente bioadesivo, na forma de um polímero catiónico.
BR9809453-0A 1997-05-24 1998-05-22 Composição de suprimento de medicamento para a liberação controlada de um ingrediente ativo dentro do meio-ambiente do estÈmago, uso da mesma, formulação farmacêutica, processo para obter gastrorretenção, para o tratamento ou profilaxia de uma doença, para melhorar a absorção gastrointestinal de medicamentos, e para a preparação de uma composição, e, estojo de partes para uso no tratamento de infecção por h. pylori. BR9809453A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710699.1A GB9710699D0 (en) 1997-05-24 1997-05-24 Gastro-retentive controlled release system
PCT/GB1998/001513 WO1998052547A1 (en) 1997-05-24 1998-05-22 Gastroretentive controlled release microspheres for improved drug delivery

Publications (1)

Publication Number Publication Date
BR9809453A true BR9809453A (pt) 2000-06-20

Family

ID=10812970

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809453-0A BR9809453A (pt) 1997-05-24 1998-05-22 Composição de suprimento de medicamento para a liberação controlada de um ingrediente ativo dentro do meio-ambiente do estÈmago, uso da mesma, formulação farmacêutica, processo para obter gastrorretenção, para o tratamento ou profilaxia de uma doença, para melhorar a absorção gastrointestinal de medicamentos, e para a preparação de uma composição, e, estojo de partes para uso no tratamento de infecção por h. pylori.

Country Status (22)

Country Link
US (1) US6207197B1 (pt)
EP (1) EP0984774B1 (pt)
JP (1) JP2001525848A (pt)
KR (1) KR20010012857A (pt)
CN (1) CN1257425A (pt)
AR (1) AR012854A1 (pt)
AT (1) ATE270880T1 (pt)
AU (1) AU737818B2 (pt)
BR (1) BR9809453A (pt)
CA (1) CA2285580A1 (pt)
DE (1) DE69825049T2 (pt)
ES (1) ES2226137T3 (pt)
GB (2) GB9710699D0 (pt)
HU (1) HUP0002935A3 (pt)
IL (1) IL132453A0 (pt)
NO (1) NO995753D0 (pt)
NZ (1) NZ338105A (pt)
PL (1) PL336037A1 (pt)
PT (1) PT984774E (pt)
SK (1) SK148999A3 (pt)
WO (1) WO1998052547A1 (pt)
ZA (1) ZA984379B (pt)

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PT984774E (pt) 2004-11-30
SK148999A3 (en) 2000-07-11
ATE270880T1 (de) 2004-07-15
AU7664298A (en) 1998-12-11
GB2341550B (en) 2002-01-09
NZ338105A (en) 2001-04-27
DE69825049T2 (de) 2005-07-21
NO995753L (no) 1999-11-24
ZA984379B (en) 1999-11-22
US6207197B1 (en) 2001-03-27
AU737818B2 (en) 2001-08-30
KR20010012857A (ko) 2001-02-26
GB9710699D0 (en) 1997-07-16
IL132453A0 (en) 2001-03-19
GB2341550A (en) 2000-03-22
ES2226137T3 (es) 2005-03-16
CA2285580A1 (en) 1998-11-26
HUP0002935A2 (hu) 2000-12-28
AR012854A1 (es) 2000-11-22
PL336037A1 (en) 2000-06-05
NO995753D0 (no) 1999-11-24
GB9926405D0 (en) 2000-01-12
DE69825049D1 (de) 2004-08-19
EP0984774B1 (en) 2004-07-14
WO1998052547A1 (en) 1998-11-26
CN1257425A (zh) 2000-06-21
HUP0002935A3 (en) 2001-04-28
EP0984774A1 (en) 2000-03-15
JP2001525848A (ja) 2001-12-11

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