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BR9306841A - Composição farmacêutica processo para proporcionar um tratamento anti-histamínico o qual não induz qualquer arritmia cardíaca significativa em um paciente ser humano e uso de uma composição para a mnaufactura de um medicamento para uso em um tratamento anti-histamínico - Google Patents

Composição farmacêutica processo para proporcionar um tratamento anti-histamínico o qual não induz qualquer arritmia cardíaca significativa em um paciente ser humano e uso de uma composição para a mnaufactura de um medicamento para uso em um tratamento anti-histamínico

Info

Publication number
BR9306841A
BR9306841A BR9306841A BR9306841A BR9306841A BR 9306841 A BR9306841 A BR 9306841A BR 9306841 A BR9306841 A BR 9306841A BR 9306841 A BR9306841 A BR 9306841A BR 9306841 A BR9306841 A BR 9306841A
Authority
BR
Brazil
Prior art keywords
antihistamine treatment
human patient
cardiac arrhythmia
providing
treatment
Prior art date
Application number
BR9306841A
Other languages
English (en)
Inventor
James W Young
Raymond L Woosley
Nancy M Gray
Yiwang Chen
Original Assignee
Sepracor Inc
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27129882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9306841(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc, Univ Georgetown filed Critical Sepracor Inc
Publication of BR9306841A publication Critical patent/BR9306841A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
BR9306841A 1992-08-03 1993-08-03 Composição farmacêutica processo para proporcionar um tratamento anti-histamínico o qual não induz qualquer arritmia cardíaca significativa em um paciente ser humano e uso de uma composição para a mnaufactura de um medicamento para uso em um tratamento anti-histamínico BR9306841A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92418292A 1992-08-03 1992-08-03
US92415692A 1992-08-03 1992-08-03
PCT/US1993/007260 WO1994003170A1 (en) 1992-08-03 1993-08-03 Terfenadine metabolites and their optically pure isomers for treating allergic disorders

Publications (1)

Publication Number Publication Date
BR9306841A true BR9306841A (pt) 1998-12-08

Family

ID=27129882

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9306841A BR9306841A (pt) 1992-08-03 1993-08-03 Composição farmacêutica processo para proporcionar um tratamento anti-histamínico o qual não induz qualquer arritmia cardíaca significativa em um paciente ser humano e uso de uma composição para a mnaufactura de um medicamento para uso em um tratamento anti-histamínico

Country Status (24)

Country Link
US (1) US5375693A (pt)
EP (4) EP0701443B2 (pt)
JP (6) JP3041954B2 (pt)
KR (1) KR950702420A (pt)
AT (3) ATE322899T1 (pt)
AU (3) AU675240B2 (pt)
BR (1) BR9306841A (pt)
CA (1) CA2141572C (pt)
CZ (1) CZ27495A3 (pt)
DE (5) DE69334008T2 (pt)
DK (3) DK0701443T4 (pt)
ES (3) ES2284740T3 (pt)
FI (1) FI950467L (pt)
GB (1) GB2284351B (pt)
GR (3) GR960300024T1 (pt)
HK (1) HK1045806B (pt)
HU (1) HU226242B1 (pt)
NO (1) NO310644B1 (pt)
PL (1) PL174373B1 (pt)
PT (2) PT1214937E (pt)
RO (1) RO116043B1 (pt)
RU (1) RU2167657C2 (pt)
SK (1) SK12495A3 (pt)
WO (1) WO1994003170A1 (pt)

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AU679910B2 (en) * 1992-05-11 1997-07-17 Merrell Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
DK0701443T4 (da) * 1992-08-03 2000-12-18 Sepracor Inc Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
ATE254594T1 (de) * 1993-06-24 2003-12-15 Albany Molecular Res Inc Verbindungen verwendbar als zwischenprodukte zur herstellung von piperidinderivate
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
EP0766668B1 (en) 1994-05-18 2002-07-17 Aventis Pharmaceuticals Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
US5455049A (en) * 1995-01-04 1995-10-03 Ascent Pharmaceuticals, Inc. Terfenadine oral powder
CA2213700C (en) 1995-02-28 2002-04-02 Hoechst Marion Roussel, Inc. Pharmaceutical composition for piperidinoalkanol compounds
GB9513972D0 (en) * 1995-07-08 1995-09-06 Merck Sharp & Dohme Pharmaceutical compositions
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US5733756A (en) * 1996-01-05 1998-03-31 Celgene Corporation Lactams and processes for stereoselective enrichment of lactams, amides, and esters
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6153754A (en) * 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
ES2124167B1 (es) * 1996-06-04 1999-09-16 Espanola Prod Quimicos Nuevos derivados del bencimidazol con actividad antihistaminica.
US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
PT998272E (pt) * 1997-08-26 2003-09-30 Aventis Pharma Inc Composicao farmaceutica para combinacao do descongestionante piperidinoalcanol
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
DE19913862C2 (de) * 1999-03-26 2003-04-10 Forschungszentrum Juelich Gmbh Verfahren zur biokatalysierten Umsetzung schlecht wasserlöslicher Substanzen
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
AU2002305162A1 (en) * 2001-04-09 2002-10-21 Teva Pharmaceutical Industries Ltd. Polymorphs of fexofenadine hydrochloride
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
CA2646802A1 (en) * 2001-06-18 2002-12-27 Dr. Reddy's Laboratories Ltd. Novel crystalline forms of 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-.alpha.,.alpha.-dimethylbenzene acetic acid and its hydrochloride
WO2003020274A1 (en) * 2001-08-30 2003-03-13 Aventis Pharmaceuticals Inc. Treatment of atopic dermatitis
WO2003104197A1 (en) * 2002-06-10 2003-12-18 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
TWI326214B (en) * 2002-07-17 2010-06-21 Avanir Pharmaceuticals Inc Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
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US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
JP4515121B2 (ja) 2004-03-15 2010-07-28 東芝テック株式会社 ワイヤドットプリンタヘッド及びワイヤドットプリンタ
JP4473021B2 (ja) 2004-03-22 2010-06-02 東芝テック株式会社 窒化層形成方法、磁気回路形成部材、アーマチュア、ワイヤドットプリンタヘッド及びワイヤドットプリンタ
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
JP2007532687A (ja) * 2004-04-26 2007-11-15 テバ ファーマシューティカル インダストリーズ リミティド フェキソフェナジン塩酸塩の結晶形およびその製造方法
US7498443B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of carebastine
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EP1685106A2 (en) * 2004-09-28 2006-08-02 Teva Pharmaceutical Industries, Inc. Fexofendadine crystal form and processes for its preparation thereof
US20060127421A1 (en) * 2004-12-09 2006-06-15 Celgene Corporation Treatment using D-threo methylphenidate
TWI435729B (zh) 2005-11-09 2014-05-01 Combinatorx Inc 治療病症之方法，組合物及套組
NZ592289A (en) * 2007-04-13 2013-03-28 Southern Res Inst Anti-Angiogenic Agents and Methods of Use
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
WO2014052836A2 (en) 2012-09-27 2014-04-03 Dunman Paul M Methods and compositions for treating infection
ES2926494T3 (es) * 2015-03-26 2022-10-26 Sen Jam Pharmaceutical Llc Combinación de naproxeno y fexofenadina para inhibir los síntomas asociados con veisalgia
DE102017130361A1 (de) 2017-12-18 2019-07-04 Lsp Innovative Automotive Systems Gmbh Statorzahn und Stator mit guter elektrischer Isolierung und gleichzeitig sehr hoher Wärmeleitfähigkeit zur Leistungssteigerung von Elektromotoren

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US922890A (en) † 1907-03-26 1909-05-25 Peder Joergen Hansen Stream-motor.
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US4552899A (en) † 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4829064A (en) † 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
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WO1993021156A1 (en) * 1992-04-10 1993-10-28 Merrell Dow Pharmaceuticals Inc. 4-diphenylmethyl piperidine derivatives and process for their preparation
AU679910B2 (en) 1992-05-11 1997-07-17 Merrell Pharmaceuticals Inc. Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
DK0701443T4 (da) 1992-08-03 2000-12-18 Sepracor Inc Terfenadinmetabolitter og deres optisk rene isomerer til behandling af allergiske lidelser
ATE254594T1 (de) * 1993-06-24 2003-12-15 Albany Molecular Res Inc Verbindungen verwendbar als zwischenprodukte zur herstellung von piperidinderivate
DK0705245T3 (da) * 1993-06-25 2003-04-14 Merrell Pharma Inc Nye mellemprodukter til fremstilling af antihistaminiske 4-diphenylmethyl/diphenylmethoxy-piperidinforbindelser
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CA2128821A1 (en) * 1993-07-27 1995-01-28 Dilip J. Gole Freeze-dried pharmaceutical dosage form and process for separation thereof
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate

Also Published As

Publication number Publication date
ATE162399T1 (de) 1998-02-15
DK0701443T4 (da) 2000-12-18
DK0701443T3 (da) 1998-02-09
ES2086270T5 (es) 2001-02-01
DE69334145D1 (de) 2007-07-12
JP3288661B2 (ja) 2002-06-04
WO1994003170A1 (en) 1994-02-17
FI950467A7 (fi) 1995-03-31
PT815860E (pt) 2006-08-31
NO950374L (no) 1995-03-29
DE69334008D1 (de) 2006-05-24
CZ27495A3 (en) 1996-09-11
DE9320925U1 (de) 1995-08-31
NO310644B1 (no) 2001-08-06
EP0701443B2 (en) 2000-11-22
ES2284740T3 (es) 2007-11-16
PL174373B1 (pl) 1998-07-31
AU675240B2 (en) 1997-01-30
DK1214937T3 (da) 2007-09-17
GR3035417T3 (en) 2001-05-31
GB2284351A (en) 1995-06-07
EP0815860B1 (en) 2006-04-12
EP0701443A1 (en) 1996-03-20
ES2086270T3 (es) 1998-03-01
GR3026530T3 (en) 1998-07-31
EP1214937B1 (en) 2007-05-30
ATE363283T1 (de) 2007-06-15
GR960300024T1 (en) 1996-05-31
JP3288660B2 (ja) 2002-06-04
JP2000086513A (ja) 2000-03-28
ES2257757T3 (es) 2006-08-01
ES2086270T1 (es) 1996-07-01
EP1688142A1 (en) 2006-08-09
DE69316660T3 (de) 2001-04-05
EP1214937A2 (en) 2002-06-19
DE69316660T2 (de) 1998-05-07
HK1045806A1 (en) 2002-12-13
JP2000086512A (ja) 2000-03-28
DE69316660D1 (de) 1998-02-26
AU4798693A (en) 1994-03-03
CA2141572C (en) 2001-02-06
DE701443T1 (de) 1997-01-30
JPH08500348A (ja) 1996-01-16
AU7182296A (en) 1997-01-30
CA2141572A1 (en) 1994-02-17
AU1842999A (en) 1999-04-29
GB9502183D0 (en) 1995-03-22
JP3037697B2 (ja) 2000-04-24
PT1214937E (pt) 2007-07-25
KR950702420A (ko) 1995-07-29
US5375693A (en) 1994-12-27
RU95107881A (ru) 1996-11-27
DE69334145T2 (de) 2008-01-24
EP0815860A3 (en) 1998-01-14
GB2284351B (en) 1996-11-27
DK0815860T3 (da) 2006-08-14
JP3288662B2 (ja) 2002-06-04
JP2000086516A (ja) 2000-03-28
RU2167657C2 (ru) 2001-05-27
FI950467A0 (fi) 1995-02-02
HU9500313D0 (en) 1995-03-28
EP0815860A2 (en) 1998-01-07
DE69334008T2 (de) 2006-10-19
JP2000086515A (ja) 2000-03-28
JP2000086514A (ja) 2000-03-28
PL307339A1 (en) 1995-05-15
RO116043B1 (ro) 2000-10-30
SK12495A3 (en) 1997-01-08
EP1214937A3 (en) 2002-10-30
NO950374D0 (no) 1995-02-01
EP0701443B1 (en) 1998-01-21
HUT71889A (en) 1996-02-28
JP3041954B2 (ja) 2000-05-15
ATE322899T1 (de) 2006-04-15
HK1045806B (en) 2008-03-14
FI950467L (fi) 1995-03-31
HU226242B1 (en) 2008-07-28

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal