BR9611401B1 - 2-azetidinonas substituìdas com açúcar úteis como agentes hipocolesterolêmicos, composição farmacêutica e kit contendo as mesmas . - Google Patents

2-azetidinonas substituìdas com açúcar úteis como agentes hipocolesterolêmicos, composição farmacêutica e kit contendo as mesmas .

Info

Publication number: BR9611401B1
Authority: BR; Brazil
Prior art keywords: pharmaceutical composition; kit containing; hypocholesterolemic agents; sugar substituted; azetidinones useful
Prior art date: 1995-10-31

Application number

BRPI9611401-0A

Other languages

English (en)

Other versions

BR9611401A (pt

Inventor

Nathan P Yumibe

Kevin B Alton

Margaret Van Heek

Harry R Davis

Wayne D Vaccaro

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-31

Filing date

1996-10-29

Publication date

2010-08-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26677904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9611401(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-10-29 Application filed filed Critical

1999-01-05 Publication of BR9611401A publication Critical patent/BR9611401A/pt

2010-08-10 Publication of BR9611401B1 publication Critical patent/BR9611401B1/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Vascular Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)

BRPI9611401-0A 1995-10-31 1996-10-29 2-azetidinonas substituìdas com açúcar úteis como agentes hipocolesterolêmicos, composição farmacêutica e kit contendo as mesmas . BR9611401B1 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US818595P	1995-10-31	1995-10-31
US57084795A	1995-12-12	1995-12-12
PCT/US1996/016823 WO1997016455A1 (en)	1995-10-31	1996-10-29	Sugar-substituted 2-azetidinones useful as hypocholesterolemic a gents

Publications (2)

Publication Number	Publication Date
BR9611401A BR9611401A (pt)	1999-01-05
BR9611401B1 true BR9611401B1 (pt)	2010-08-10

Family

ID=26677904

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BRPI9611401-0A BR9611401B1 (pt)	1995-10-31	1996-10-29	2-azetidinonas substituìdas com açúcar úteis como agentes hipocolesterolêmicos, composição farmacêutica e kit contendo as mesmas .
BRPI9612998-0A BR9612998B1 (pt)	1995-10-31	1996-10-29	2-azetidinonas substituÍdas com aÇécar éteis como agentes hipocolesterolÊmicos, composiÇço farmacÊutica e kit contendo as mesmas.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
BRPI9612998-0A BR9612998B1 (pt)	1995-10-31	1996-10-29	2-azetidinonas substituÍdas com aÇécar éteis como agentes hipocolesterolÊmicos, composiÇço farmacÊutica e kit contendo as mesmas.

Country Status (27)

Country	Link
EP (1)	EP0877750B1 (pt)
JP (2)	JP3385031B2 (pt)
KR (1)	KR100311554B1 (pt)
CN (1)	CN1103780C (pt)
AR (1)	AR004701A1 (pt)
AT (1)	ATE219495T1 (pt)
AU (1)	AU712158B2 (pt)
BR (2)	BR9611401B1 (pt)
CA (1)	CA2235943C (pt)
CY (1)	CY2353B1 (pt)
CZ (1)	CZ293957B6 (pt)
DE (1)	DE69621952T2 (pt)
DK (1)	DK0877750T3 (pt)
ES (1)	ES2175141T3 (pt)
GE (1)	GEP20033006B (pt)
HU (1)	HU226822B1 (pt)
ID (1)	ID16177A (pt)
IL (1)	IL124268A (pt)
MX (1)	MX9803447A (pt)
MY (1)	MY114803A (pt)
NO (1)	NO311692B1 (pt)
NZ (1)	NZ321766A (pt)
PL (1)	PL184698B1 (pt)
PT (1)	PT877750E (pt)
SK (1)	SK283552B6 (pt)
TW (1)	TW448181B (pt)
WO (1)	WO1997016455A1 (pt)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5633246A (en) *	1994-11-18	1997-05-27	Schering Corporation	Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents
DE10042447A1 (de) *	2000-08-29	2002-03-28	Aventis Pharma Gmbh	Protein aus dem Darm von Wirbeltieren, welches Cholesterin absorbiert, sowie Verwendung dieses Proteins zur Identifizierung von Inhibitoren des intestinalen Cholesterintransports
EP1510521A1 (en) *	2000-12-20	2005-03-02	Schering Corporation	Sugar-substituted 2-Azetidinones useful as hypocholesterolemic agents
US6982251B2 (en)	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
ATE369334T1 (de) *	2000-12-20	2007-08-15	Schering Corp	Hydroxysubstituierte 2-azetidinone verwendbar als hypocholesterolemische arzneimittel
BR0116325A (pt)	2000-12-21	2003-10-14	Aventis Pharma Gmbh	1,2-difenilazetidinonas, processos para a sua preparação, medicamentos contendo estes compostos e sua aplicação para o tratamento de distúrbios do metabolismo de lipìdios
DE10064398A1 (de) *	2000-12-21	2002-06-27	Aventis Pharma Gmbh	Neue Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US20020147184A1 (en) *	2001-01-26	2002-10-10	Schering Corporation	Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
RS20100015A (sr)	2001-01-26	2010-12-31	Schering Corporation	Kombinacija aktivatora receptora aktiviranog peroksizom- proliferatorom (ppar) fenofibrata sa inhibitorom apsorpcije sterola ezetimibom za vaskularne indikacije
US7071181B2 (en)	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
HU230435B1 (hu)	2001-01-26	2016-06-28	Merck Sharp & Dohme Corp	Szubsztituált azetidinon vegyületek alkalmazása szitoszterinémia kezelésére
AU2005246926B2 (en) *	2001-01-26	2008-02-28	Merck Sharp & Dohme Corp.	The use of substituted azetidinone compounds for the treatment of sitosterolemia
TWI291957B (en) *	2001-02-23	2008-01-01	Kotobuki Pharmaceutical Co Ltd	Beta-lactam compounds, process for repoducing the same and serum cholesterol-lowering agents containing the same
US6627757B2 (en)	2001-03-28	2003-09-30	Schering Corporation	Enantioselective synthesis of azetidinone intermediate compounds
US7056906B2 (en)	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en)	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
CA2460340C (en)	2001-09-21	2011-02-15	Schering Corporation	Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
US7671047B2 (en)	2002-06-19	2010-03-02	Sanofi-Aventis Deutschland Gmbh	Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
DE10227506A1 (de) *	2002-06-19	2004-01-08	Aventis Pharma Deutschland Gmbh	Ringsubstituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US7176193B2 (en)	2002-06-19	2007-02-13	Sanofi-Aventis Deutschland Gmbh	Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
US7176194B2 (en)	2002-06-19	2007-02-13	Sanofi-Aventis Deutschland Gmbh	Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
GB0215579D0 (en)	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
AR040588A1 (es)	2002-07-26	2005-04-13	Schering Corp	Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
MXPA05004811A (es)	2002-11-06	2005-07-22	Schering Corp	Inhibidores de absorcion de colesterol para el tratamiento de trastornos autoinmunes.
MXPA05009502A (es)	2003-03-07	2005-10-18	Schering Corp	Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
MXPA05009501A (es)	2003-03-07	2005-10-18	Schering Corp	Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
CA2517571C (en)	2003-03-07	2011-07-05	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
AR041089A1 (es)	2003-05-15	2005-05-04	Merck & Co Inc	Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas
JP2005015434A (ja)	2003-06-27	2005-01-20	Kotobuki Seiyaku Kk	血清コレステロール低下剤或はアテローム性硬化症の予防又は治療剤
EP1522541A1 (en) *	2003-10-07	2005-04-13	Lipideon Biotechnology AG	Novel hypocholesterolemic compounds
US20070135357A1 (en) *	2003-10-30	2007-06-14	Sings Heather L	Anti-hypercholesterolemic compounds
WO2005061452A1 (en)	2003-12-23	2005-07-07	Astrazeneca Ab	Diphenylazetidinone derivates possessing cholesterol absorption inhibitory activity
US20060211752A1 (en)	2004-03-16	2006-09-21	Kohn Leonard D	Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
EP1877067A1 (en) *	2005-04-26	2008-01-16	Microbia, Inc.	4-biarylyl-1-phenylazetidin-2-one glucuronide derivatives for hypercholesterolemia
SA06270191B1 (ar)	2005-06-22	2010-03-29	استرازينيكا ايه بي	مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
US20080255084A1 (en)	2005-10-21	2008-10-16	Randy Lee Webb	Combination of Organic Compounds
TW200811098A (en)	2006-04-27	2008-03-01	Astrazeneca Ab	Chemical compounds
US20080319221A1 (en)	2007-06-22	2008-12-25	Bernd Junker	Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
DE102007054497B3 (de)	2007-11-13	2009-07-23	Sanofi-Aventis Deutschland Gmbh	Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
WO2010100255A1 (en)	2009-03-06	2010-09-10	Lipideon Biotechnology Ag	Pharmaceutical hypocholesterolemic compositions
CN101993403B (zh)	2009-08-11	2012-07-11	浙江海正药业股份有限公司	氮杂环丁酮类化合物及医药应用
CN103102297A (zh) *	2012-09-28	2013-05-15	北京赛林泰医药技术有限公司	一种新的依折麦布的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LT3595B (en) *	1993-01-21	1995-12-27	Schering Corp	Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents
CA2120221A1 (en) *	1993-04-23	1994-10-24	Allan W. Rey	N-substituted 2-azetidinones
US5631365A (en) *	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5627176A (en)	1994-03-25	1997-05-06	Schering Corporation	Substituted azetidinone compounds useful as hypocholesterolemic agents
US5633246A (en)	1994-11-18	1997-05-27	Schering Corporation	Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents

1996
- 1996-10-29 CZ CZ19981294A patent/CZ293957B6/cs not_active IP Right Cessation
- 1996-10-29 GE GEAP19966589A patent/GEP20033006B/en unknown
- 1996-10-29 AU AU75179/96A patent/AU712158B2/en not_active Ceased
- 1996-10-29 DE DE69621952T patent/DE69621952T2/de not_active Expired - Lifetime
- 1996-10-29 TW TW085113142A patent/TW448181B/zh not_active IP Right Cessation
- 1996-10-29 IL IL12426896A patent/IL124268A/xx not_active IP Right Cessation
- 1996-10-29 BR BRPI9611401-0A patent/BR9611401B1/pt not_active IP Right Cessation
- 1996-10-29 ES ES96937702T patent/ES2175141T3/es not_active Expired - Lifetime
- 1996-10-29 JP JP51738697A patent/JP3385031B2/ja not_active Expired - Fee Related
- 1996-10-29 PT PT96937702T patent/PT877750E/pt unknown
- 1996-10-29 PL PL96327987A patent/PL184698B1/pl not_active IP Right Cessation
- 1996-10-29 DK DK96937702T patent/DK0877750T3/da active
- 1996-10-29 NZ NZ321766A patent/NZ321766A/xx not_active IP Right Cessation
- 1996-10-29 BR BRPI9612998-0A patent/BR9612998B1/pt not_active IP Right Cessation
- 1996-10-29 CN CN96199226A patent/CN1103780C/zh not_active Expired - Lifetime
- 1996-10-29 HU HU9802539A patent/HU226822B1/hu unknown
- 1996-10-29 MY MYPI96004488A patent/MY114803A/en unknown
- 1996-10-29 EP EP96937702A patent/EP0877750B1/en not_active Expired - Lifetime
- 1996-10-29 KR KR1019980703155A patent/KR100311554B1/ko not_active Expired - Fee Related
- 1996-10-29 SK SK483-98A patent/SK283552B6/sk not_active IP Right Cessation
- 1996-10-29 AR ARP960104954A patent/AR004701A1/es not_active Application Discontinuation
- 1996-10-29 CA CA002235943A patent/CA2235943C/en not_active Expired - Lifetime
- 1996-10-29 WO PCT/US1996/016823 patent/WO1997016455A1/en not_active Ceased
- 1996-10-29 AT AT96937702T patent/ATE219495T1/de active
- 1996-10-30 ID IDP963136A patent/ID16177A/id unknown
1998
- 1998-04-29 NO NO19981950A patent/NO311692B1/no not_active IP Right Cessation
- 1998-04-30 MX MX9803447A patent/MX9803447A/es unknown
2000
- 2000-07-17 JP JP2000216704A patent/JP2001048895A/ja not_active Withdrawn
2003
- 2003-01-29 CY CY0300007A patent/CY2353B1/xx unknown

Also Published As

Publication number	Publication date
ID16177A (id)	1997-09-11
HUP9802539A3 (en)	1999-12-28
KR19990067202A (ko)	1999-08-16
PT877750E (pt)	2002-09-30
HK1012507A1 (en)	1999-08-06
EP0877750A1 (en)	1998-11-18
MX9803447A (es)	1998-09-30
PL327987A1 (en)	1999-01-04
PL184698B1 (pl)	2002-12-31
CY2353B1 (en)	2004-06-04
DE69621952T2 (de)	2003-01-16
CZ293957B6 (cs)	2004-08-18
AU712158B2 (en)	1999-10-28
CN1103780C (zh)	2003-03-26
IL124268A (en)	2005-08-31
KR100311554B1 (ko)	2002-06-20
WO1997016455A1 (en)	1997-05-09
NO311692B1 (no)	2002-01-07
NO981950L (no)	1998-06-26
ES2175141T3 (es)	2002-11-16
NO981950D0 (no)	1998-04-29
TW448181B (en)	2001-08-01
CA2235943C (en)	2002-10-01
DE69621952D1 (de)	2002-07-25
SK283552B6 (sk)	2003-09-11
SK48398A3 (en)	1998-11-04
JPH10512592A (ja)	1998-12-02
AR004701A1 (es)	1999-03-10
MY114803A (en)	2003-01-31
CA2235943A1 (en)	1997-05-09
BR9611401A (pt)	1999-01-05
HU226822B1 (en)	2009-11-30
JP2001048895A (ja)	2001-02-20
EP0877750B1 (en)	2002-06-19
DK0877750T3 (da)	2002-07-15
CZ129498A3 (cs)	1998-10-14
ATE219495T1 (de)	2002-07-15
NZ321766A (en)	1999-07-29
GEP20033006B (en)	2003-07-10
HUP9802539A2 (hu)	1998-11-30
BR9612998B1 (pt)	2010-03-23
CN1205707A (zh)	1999-01-20
JP3385031B2 (ja)	2003-03-10
AU7517996A (en)	1997-05-22

Publication	Publication Date	Title
BR9611401B1 (pt)	2010-08-10	2-azetidinonas substituìdas com açúcar úteis como agentes hipocolesterolêmicos, composição farmacêutica e kit contendo as mesmas .
FI953497A7 (fi)	1995-07-20	Spirosykloalkyylisubstituoidut atsetidinonit, jotka ovat käyttökelpoisia hypokolesteroleemisina aineina
ZA965190B (en)	1997-12-19	Pharmaceutical composition.
IS4565A (is)	1997-09-22	2-methýl-thíenó-bensódíasepín, samsetning til inntöku
BR9710372B1 (pt)	2013-02-05	composto, e, composiÇço farmacÊutica.
ES1028851Y (es)	1995-08-16	Juego de construccion.
ID26982A (id)	2001-02-22	Komposisi farmasi topiramat
BR9805993B1 (pt)	2009-05-05	composição farmacêutica de aerossol.
DE69606680D1 (de)	2000-03-23	1-Alpha, 26-dihydroxy-D-homo-vitamin D3
FI960657L (fi)	1996-08-15	Suklaakoostumus
DE69626835D1 (de)	2003-04-24	Insektizide zusammensetzung
ZA989680B (en)	1999-07-23	Pharmaceutical composition.
ZA968081B (en)	1998-03-26	Pharmaceutical composition.
FI972988A0 (fi)	1997-07-14	Menetelmiä ja farmaseuttisia koostumuksia, joissa käytetään desmetyyliselegiliiniä
BRPI9703099B8 (pt)	2021-07-06	derivado de carboidrato, e, composição farmacêutica
FI973229A7 (fi)	1997-08-05	Uusi farmaseuttinen koostumus
LV11727A (lv)	1997-04-20	Farmaceitiska kompozicija
ZA987392B (en)	2000-02-17	Pharmaceutical composition.
TR199601012A2 (tr)	1997-06-21	Sampuan terkibi.
FI973280A7 (fi)	1997-08-08	Farmaseuttinen koostumus
BR9610382A (pt)	1999-07-06	Composição de tratamento do cableo
BR9605777A (pt)	1998-08-25	Composição farmacêutica
BR9603032A (pt)	1998-05-05	Composição pesticida
BR9605131A (pt)	1998-07-07	Composição farmacêutica
BR9804596B1 (pt)	2008-11-18	composiÇço cosmÉtica bifÁsica.

Legal Events

Date	Code	Title	Description
2004-12-14	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2005-11-22	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2007-05-08	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2007-12-11	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE NAO ATENDE AO REQUISITO DA SUFICIENCIA DESCRITIVA ( ART. 24 COMBINADO COM O ART. 25 DA LPI)
2008-03-11	B12B	Appeal against refusal [chapter 12.2 patent gazette]
2010-08-10	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/08/2010, OBSERVADAS AS CONDICOES LEGAIS.
2013-10-01	B25D	Requested change of name of applicant approved	Owner name: MERCK SHARP AND DOHME CORP. (US)
2013-10-08	B22O	Other matters related to patents and certificates of addition of invention: legal action concerning patent	Free format text: INPI-52400.061553/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132273-17.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU:OSI PHARMACEUTICALS, LLC , PFIZER, SANOFI-AVERTI, , SANOFI-AVERTI DEUTCHLAND GMBH, SCHERING CORPORATION.
2013-10-15	B25G	Requested change of headquarter approved	Owner name: MERCK SHARP AND DOHME CORP. (US)
2019-10-01	B21A	Patent or certificate of addition expired [chapter 21.1 patent gazette]	Free format text: PATENTE EXTINTA EM 29/10/2016, CONFORME DETERMINADO NO INPI-52400.061553/2013-52 SECAO JUDICIARIA DO RIO DE JANEIRO 9A VARA FEDERAL DO RIO DE JANEIRO PROCESSO : NO 0132273-17.2013.4.02.5101.
2019-11-26	B21H	Decision of lapse of a patent or of a certificate of addition of invention cancelled [chapter 21.8 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 21.1 NA RPI NO 2543 DE 01/10/2019 POR TER SIDO INDEVIDA.
2020-07-21	B19A	Notification of judicial decision: notification of judicial decision	Free format text: INPI NO 52402.005802/2020-39 TRIBUNAL REGIONAL FEDERAL DA 2A REGIAO PROCESSO : NO 5004917-81.2020.4.02.0000/RJ REQUERENTE: MERCK SHARP AND DOHME CORPORATION REQUERENTE: PFIZER PRODUCTS REQUERENTE: OSI PHARMACEUTICALS, LLC. REQUERIDO: INPI-INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL MPF: MINISTERIO PUBLICO FEDERAL AMICUS CURIAE: ASSOCIACAO BRAS DAS IND DE Q FINA B E SUAS ESP ABIFINA AMICUS CURIAE: INTERFARMA ASSOCIACAO DA INDUSTRIA FARMACEUTICA DE PESQUISA INTERESSADO: SANOFI-AVENTIS DEUTSCHLAND GMBM INTERESSADO: SANOFI AVENTIS INTERESSADO: ZOETIS LLC DECISAO: ANTE O EXPOSTO, ATRIBUO EFEITO SUSPENSIVO A APELACAO INTERPOSTA NO PROCESSO NO 0132273-17.2013.4.02.5101 POR OSI PHARMA
2020-11-24	B19A	Notification of judicial decision: notification of judicial decision	Free format text: INPI NO 52400.061553/2013-52 NUP: 00848.000587/2019-11 (REF. 00408.129415/2017-38) INTERESSADOS: THE PROVOST FELLOWS AND SCHOLARS OF THE HOLY UNDIVIDED TRINITYOF QUEEN ELIZABETH NEAR DUBLIN E OUTROS DECISAO: ?EM FACE DO EXPOSTO, CONCEDO A TUTELA PROVISORIA POSTULADA PARA DETERMINAR O EFEITO SUSPENSIVO AO RECURSO ESPECIAL, MANTENDO A VIGENCIA DAS PATENTES TIPO MAILBOX CONCEDIDAS PELO INPI, CONFORME O ENTENDIMENTO ANTERIOR, ATE POSTERIOR SOLUCAO DA CAUSA".