BR0311749A - Processo para produzir um composto, e, composto - Google Patents
Processo para produzir um composto, e, compostoInfo
- Publication number
- BR0311749A BR0311749A BR0311749-9A BR0311749A BR0311749A BR 0311749 A BR0311749 A BR 0311749A BR 0311749 A BR0311749 A BR 0311749A BR 0311749 A BR0311749 A BR 0311749A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- producing
- protecting group
- arila
- alkylene
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- -1 and Chemical class 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000004294 cyclic thioethers Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003573 thiols Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"PROCESSO PARA PRODUZIR UM COMPOSTO, E, COMPOSTO". Um processo para produzir um tioéter cíclico e um intermediário sintético do mesmo. Particularmente, um composto de fórmula geral (5): em que G^ 1^ representa um alquileno, R^ 1^ representa um grupo de proteção para tiol, R^ 2^ representa hidrogênio ou um grupo de proteção para amino, e Ar representa uma arila, etc.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002169967 | 2002-06-11 | ||
| PCT/JP2003/007291 WO2003104240A1 (ja) | 2002-06-11 | 2003-06-09 | 環状チオエーテル類の製造法及びその合成中間体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0311749A true BR0311749A (pt) | 2005-03-08 |
Family
ID=29727753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0311749-9A BR0311749A (pt) | 2002-06-11 | 2003-06-09 | Processo para produzir um composto, e, composto |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1533314A4 (pt) |
| KR (1) | KR20050008813A (pt) |
| CN (1) | CN100334092C (pt) |
| AU (1) | AU2003242092A1 (pt) |
| BR (1) | BR0311749A (pt) |
| CA (1) | CA2489255A1 (pt) |
| IL (1) | IL165512A0 (pt) |
| TW (1) | TW200403203A (pt) |
| WO (1) | WO2003104240A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2812526A1 (en) | 2010-05-06 | 2011-11-10 | Vertex Pharmaceuticals Incorporated | Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels |
| DK2670752T3 (en) | 2011-02-02 | 2016-07-04 | Vertex Pharma | PYRROLOPYRAZINE SPIROCYCLIC PIPERIDINAMIDE AS ION CHANNEL MODULATORS |
| WO2012112743A1 (en) | 2011-02-18 | 2012-08-23 | Vertex Pharmaceuticals Incorporated | Chroman - spirocyclic piperidine amides as modulators of ion channels |
| EP2686325B1 (en) | 2011-03-14 | 2016-12-14 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2135494C1 (ru) * | 1995-12-01 | 1999-08-27 | Санкио Компани Лимитед | Гетероциклические соединения и композиция на их основе, проявляющая антагонистическое действие в отношении рецепторов тахикинина |
| PT1048658E (pt) * | 1997-12-04 | 2005-10-31 | Sankyo Co | Derivados heterociclicos acilados aliciclicos |
| AU6621600A (en) * | 1999-08-04 | 2001-03-05 | Millennium Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
| WO2001029027A1 (en) * | 1999-10-22 | 2001-04-26 | Sankyo Company, Limited | 2-alkoxybenzene derivatives |
| EP1363890A4 (en) * | 2001-02-07 | 2009-06-10 | Ore Pharmaceuticals Inc | MELANOCORTIN-4-RECEPTOR BINDING COMPOUNDS AND METHOD FOR THEIR APPLICATION |
-
2003
- 2003-06-09 AU AU2003242092A patent/AU2003242092A1/en not_active Abandoned
- 2003-06-09 WO PCT/JP2003/007291 patent/WO2003104240A1/ja not_active Ceased
- 2003-06-09 EP EP03736114A patent/EP1533314A4/en not_active Withdrawn
- 2003-06-09 CA CA002489255A patent/CA2489255A1/en not_active Abandoned
- 2003-06-09 BR BR0311749-9A patent/BR0311749A/pt not_active IP Right Cessation
- 2003-06-09 CN CNB038189321A patent/CN100334092C/zh not_active Expired - Fee Related
- 2003-06-09 KR KR10-2004-7020086A patent/KR20050008813A/ko not_active Withdrawn
- 2003-06-10 TW TW092115625A patent/TW200403203A/zh unknown
-
2004
- 2004-12-02 IL IL16551204A patent/IL165512A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003242092A1 (en) | 2003-12-22 |
| CA2489255A1 (en) | 2003-12-18 |
| IL165512A0 (en) | 2006-01-15 |
| KR20050008813A (ko) | 2005-01-21 |
| CN100334092C (zh) | 2007-08-29 |
| TW200403203A (en) | 2004-03-01 |
| EP1533314A4 (en) | 2006-08-02 |
| CN1675221A (zh) | 2005-09-28 |
| WO2003104240A1 (ja) | 2003-12-18 |
| EP1533314A1 (en) | 2005-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2116 DE 26/07/2011. |