[go: up one dir, main page]

BG101163A - 8-флуоро-антрациклини, процеси за тяхното получаване и фармацевтични състави съдържащи ги - Google Patents

8-флуоро-антрациклини, процеси за тяхното получаване и фармацевтични състави съдържащи ги

Info

Publication number
BG101163A
BG101163A BG101163A BG10116397A BG101163A BG 101163 A BG101163 A BG 101163A BG 101163 A BG101163 A BG 101163A BG 10116397 A BG10116397 A BG 10116397A BG 101163 A BG101163 A BG 101163A
Authority
BG
Bulgaria
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
anthracyclines
fluoro
Prior art date
Application number
BG101163A
Other languages
Bulgarian (bg)
English (en)
Inventor
Fabio Animati
Federico Arcamone
Giuseppe Giannini
Paolo Lombardi
Edith Monteagudo
Original Assignee
A. Menarini Industrie Farmaceutiche Riunite S.R.L.
Bristol-Myers Squibb S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A. Menarini Industrie Farmaceutiche Riunite S.R.L., Bristol-Myers Squibb S.P.A. filed Critical A. Menarini Industrie Farmaceutiche Riunite S.R.L.
Publication of BG101163A publication Critical patent/BG101163A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/38—Quinones containing —CHO or non—quinoid keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG101163A 1994-08-04 1997-01-22 8-флуоро-антрациклини, процеси за тяхното получаване и фармацевтични състави съдържащи ги BG101163A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941696A IT1271689B (it) 1994-08-04 1994-08-04 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
PCT/EP1995/003061 WO1996004292A1 (en) 1994-08-04 1995-08-01 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
BG101163A true BG101163A (bg) 1997-09-30

Family

ID=11369446

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101163A BG101163A (bg) 1994-08-04 1997-01-22 8-флуоро-антрациклини, процеси за тяхното получаване и фармацевтични състави съдържащи ги

Country Status (25)

Country Link
US (1) US5814608A (xx)
EP (1) EP0776328B1 (xx)
JP (1) JPH10503509A (xx)
AT (1) ATE172980T1 (xx)
AU (1) AU700929B2 (xx)
BG (1) BG101163A (xx)
BR (1) BR9508518A (xx)
CA (1) CA2196752A1 (xx)
CZ (1) CZ28097A3 (xx)
DE (1) DE69505828T2 (xx)
DK (1) DK0776328T3 (xx)
ES (1) ES2126923T3 (xx)
FI (1) FI970455L (xx)
HR (1) HRP950436A2 (xx)
HU (1) HUT76339A (xx)
IL (1) IL114791A0 (xx)
IT (1) IT1271689B (xx)
NO (1) NO305561B1 (xx)
NZ (1) NZ291426A (xx)
PL (1) PL319630A1 (xx)
RU (1) RU2146261C1 (xx)
SK (1) SK13797A3 (xx)
TJ (1) TJ245B (xx)
WO (1) WO1996004292A1 (xx)
ZA (1) ZA956480B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058543A1 (en) * 1998-05-13 1999-11-18 Instytut Farmaceutyczny New n-alkyloxycarbonyl derivatives of monosaccharides l-acosamine and l-daunosamine
DE06848583T1 (de) * 2005-12-13 2011-03-17 Solux Corporation, San Diego Verfahren zur herstellung von 4-demethyldaunorubicin
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
RU2642068C1 (ru) * 2017-04-26 2018-01-24 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) N-пиперонильные производные даунорубицина, обладающие антипролиферативными свойствами

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61501388A (ja) * 1983-10-19 1986-07-10 ザ　ユニヴア−シテイ　オブ　メルボルン 有機化合物類
MA21995A1 (fr) * 1989-11-13 1991-07-01 Menarini Farma Ind Nouvelles fluoronaphthacenediones,leurs derives glycozyles et leurs procedes de fabrication .
IT1241927B (it) * 1990-05-14 1994-02-01 Menarini Farma Ind 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono
HU9203720D0 (en) * 1990-06-11 1993-03-29 Iaf Biochem Int Method for producing heterocyclic derivatives of anthracyclinole and anthracycline
IT1262565B (it) * 1993-09-30 1996-07-04 Menarini Farma Ind Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.

Also Published As

Publication number Publication date
FI970455A0 (fi) 1997-02-03
US5814608A (en) 1998-09-29
AU700929B2 (en) 1999-01-14
CA2196752A1 (en) 1996-02-15
RU2146261C1 (ru) 2000-03-10
FI970455A7 (fi) 1997-02-03
NO305561B1 (no) 1999-06-21
ATE172980T1 (de) 1998-11-15
IT1271689B (it) 1997-06-04
EP0776328B1 (en) 1998-11-04
PL319630A1 (en) 1997-08-18
DK0776328T3 (da) 1999-07-19
FI970455L (fi) 1997-02-03
AU3255395A (en) 1996-03-04
ZA956480B (en) 1996-03-14
DE69505828T2 (de) 1999-05-20
DE69505828D1 (de) 1998-12-10
ITMI941696A1 (it) 1996-02-04
JPH10503509A (ja) 1998-03-31
SK13797A3 (en) 1997-07-09
EP0776328A1 (en) 1997-06-04
BR9508518A (pt) 1997-12-23
CZ28097A3 (en) 1997-08-13
HRP950436A2 (en) 1997-10-31
ES2126923T3 (es) 1999-04-01
NO970059L (no) 1997-01-08
IL114791A0 (en) 1995-11-27
WO1996004292A1 (en) 1996-02-15
ITMI941696A0 (it) 1994-08-04
HUT76339A (en) 1997-08-28
NZ291426A (en) 1998-05-27
NO970059D0 (no) 1997-01-08
TJ245B (en) 2001-08-06

Similar Documents

Publication Publication Date Title
PT960107E (pt) Compostos de paclitaxel 6-tio-substituidos
BG103485A (en) Ketobanzamides as calpain inhibitors
MX9203396A (es) Monohidrato de furoato de mometasona, proceso para producirlo y composiciones farmaceuticas.
BR0112030A (pt) Novos compostos que possuem atividade antibacteriana, antifúngica ou antitumor
IL128425A0 (en) Taxane derivatives their preparation and pharmaceutical compositions containing them
SE9802729D0 (sv) Novel Compounds
ES2181744T3 (es) Hidratos de paclitaxel cristalinos.
EA200200479A1 (ru) Новые олигосахариды, их получение и содержащие их фармацевтические композиции
DE69709407D1 (de) Zytotoxischer aminozucker und verwandte zuckerderivate von indolopyrrolocarbazolen
IL117091A0 (en) Methylphenyloxazolidinone derivatives pharmaceutical compositions containing the same and processes for the preparation thereof
MX9601994A (es) Profarmacos de derivados de paclitaxel.
SE9802937D0 (sv) Novel compounds
CA2152771A1 (en) 7-o-ethers of taxane derivatives
PT971922E (pt) Compostos de tetra-hidropirido
MY120683A (en) New phenylamidine derivatives, processes for their preparation and their use as pharmaceuticals.
PT1107793E (pt) Conjugados de dextrano-leptina, composicoes farmaceuticas e processos relacionados
FR2575466B1 (fr) Nouveaux complexes de silicium hexacoordines, leur procede de preparation et leur application
BG101163A (bg) 8-флуоро-антрациклини, процеси за тяхното получаване и фармацевтични състави съдържащи ги
SE9904128D0 (sv) Novel compounds
YU4497A (sh) Novi heteroaril - oksazolidinoni
DK0577745T3 (da) Bis-naphtalimider indeholdende amid- og thioamid-forbindelsesstykker som anticancermidler.
TR200003203T2 (tr) Karboksaldehitin saflaştırılması
YU48200A (sh) Farmaceutski preparati
MX9803791A (es) Intermediarios novedosos y su uso para preparar bisindolilmaleimidas n,n'-puenteadas.
PT1011329E (pt) Paclitaxeis de 7-metiltio-oxometilo e 7-metiltiodioxometilo