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BG106236A - Melt granulation - Google Patents

Melt granulation

Info

Publication number
BG106236A
BG106236A BG106236A BG10623601A BG106236A BG 106236 A BG106236 A BG 106236A BG 106236 A BG106236 A BG 106236A BG 10623601 A BG10623601 A BG 10623601A BG 106236 A BG106236 A BG 106236A
Authority
BG
Bulgaria
Prior art keywords
melt granulation
bitterness
diabetics
derivatives
site
Prior art date
Application number
BG106236A
Other languages
Bulgarian (bg)
Inventor
Darja TEMELJOTOV
Judita Sirca
Milojka Mohar
Mateja Salobir
Andrej Golmajer
Marko Opresnik
Original Assignee
Lek Pharmaceutical And Chemical Company D.D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceutical And Chemical Company D.D filed Critical Lek Pharmaceutical And Chemical Company D.D
Publication of BG106236A publication Critical patent/BG106236A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
  • Glanulating (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

The invention relates to a method for coating of a pharmaceutical preparation and its derivatives by the melt granulation for effective masking of bitterness, and a new oral pharmaceutical formulation suitable also for diabetics, which at the same time also enables variations in the rate and site of the release of the active component. 14 claims
BG106236A 1999-05-19 2001-12-19 Melt granulation BG106236A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI9900119A SI20244A (en) 1999-05-19 1999-05-19 Melt granulation
PCT/SI2000/000013 WO2000069415A2 (en) 1999-05-19 2000-05-18 Melt granulation

Publications (1)

Publication Number Publication Date
BG106236A true BG106236A (en) 2002-08-30

Family

ID=20432471

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106236A BG106236A (en) 1999-05-19 2001-12-19 Melt granulation

Country Status (13)

Country Link
EP (1) EP1183013A2 (en)
AU (1) AU4969700A (en)
BG (1) BG106236A (en)
CZ (1) CZ20014133A3 (en)
EE (1) EE200100607A (en)
HR (1) HRP20010932A2 (en)
HU (1) HUP0201233A3 (en)
PL (1) PL351654A1 (en)
RU (1) RU2001134166A (en)
SI (1) SI20244A (en)
SK (1) SK16642001A3 (en)
WO (1) WO2000069415A2 (en)
YU (1) YU82001A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0109544A (en) * 2000-03-28 2003-06-10 Biochemie Gmbh Granules with hidden flavor
MXPA03003146A (en) * 2000-10-13 2004-12-06 Advancis Pharmaceuticals Extended release erythromycin derivatives.
WO2003070223A1 (en) * 2002-02-21 2003-08-28 Otsuka Pharmaceutical Co., Ltd. Sustained release preparations and process for producing the same
US7943585B2 (en) 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019486A1 (en) * 1990-06-14 1991-12-26 Kalmo Enterprises, Inc. Stable aqueous drug suspensions
JP3265680B2 (en) * 1992-03-12 2002-03-11 大正製薬株式会社 Oral pharmaceutical composition
CA2150119C (en) * 1992-11-30 2005-03-15 Robert C. Cuca Tastemasked pharmaceutical materials
IT1312058B1 (en) * 1999-04-09 2002-04-04 Pharmaplus S R L METHOD FOR MICRO-ENCAPSULATION OF MEDICATIONS.

Also Published As

Publication number Publication date
HUP0201233A2 (en) 2002-08-28
AU4969700A (en) 2000-12-05
EP1183013A2 (en) 2002-03-06
PL351654A1 (en) 2003-05-19
YU82001A (en) 2004-07-15
HRP20010932A2 (en) 2003-04-30
SK16642001A3 (en) 2002-05-09
CZ20014133A3 (en) 2002-03-13
WO2000069415A2 (en) 2000-11-23
EE200100607A (en) 2003-02-17
SI20244A (en) 2000-12-31
RU2001134166A (en) 2003-08-27
WO2000069415A3 (en) 2001-04-26
HUP0201233A3 (en) 2003-10-28

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