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TR199801861T2 - Pharmaceutically useful compositions. - Google Patents

Pharmaceutically useful compositions.

Info

Publication number
TR199801861T2
TR199801861T2 TR1998/01861T TR9801861T TR199801861T2 TR 199801861 T2 TR199801861 T2 TR 199801861T2 TR 1998/01861 T TR1998/01861 T TR 1998/01861T TR 9801861 T TR9801861 T TR 9801861T TR 199801861 T2 TR199801861 T2 TR 199801861T2
Authority
TR
Turkey
Prior art keywords
pharmaceutically useful
useful compositions
compositions
arylpyrazolinquinoline
medicines
Prior art date
Application number
TR1998/01861T
Other languages
Turkish (tr)
Inventor
Bantick John
Bonnert Roger
Cage Peter
Donald David
Furber Mark
Hirst Simon
Perry Matthew
Phillips Eifion
Original Assignee
Astra Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605803.7A external-priority patent/GB9605803D0/en
Priority claimed from GBGB9610474.0A external-priority patent/GB9610474D0/en
Priority claimed from GBGB9610894.9A external-priority patent/GB9610894D0/en
Priority claimed from GBGB9700862.7A external-priority patent/GB9700862D0/en
Application filed by Astra Pharmaceuticals Ltd. filed Critical Astra Pharmaceuticals Ltd.
Publication of TR199801861T2 publication Critical patent/TR199801861T2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Bulus, 2-arilpirazolinkinolin ve kinnolinon türevleri, hazirlanmasi için metod, ilaç olarak kullanimlari ve onlari içeren farmasötik formülasyonlarla ilgilidir.The invention relates to 2-arylpyrazolinquinoline and quinolinone derivatives, the method for their preparation, their use as medicines, and pharmaceutical formulations containing them.

TR1998/01861T 1996-03-20 1997-03-20 Pharmaceutically useful compositions. TR199801861T2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9605803.7A GB9605803D0 (en) 1996-03-20 1996-03-20 Pharmaceutically-active compound
GBGB9610474.0A GB9610474D0 (en) 1996-05-18 1996-05-18 Pharmaceutically active compounds
GBGB9610894.9A GB9610894D0 (en) 1996-05-24 1996-05-24 Pharmaceutically useful compounds
GBGB9700862.7A GB9700862D0 (en) 1997-01-16 1997-01-16 Pharmaceutically useful compounds

Publications (1)

Publication Number Publication Date
TR199801861T2 true TR199801861T2 (en) 1998-12-21

Family

ID=27451427

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/01861T TR199801861T2 (en) 1996-03-20 1997-03-20 Pharmaceutically useful compositions.

Country Status (19)

Country Link
EP (1) EP0888347A1 (en)
JP (1) JP2000506884A (en)
KR (1) KR20000064716A (en)
CN (1) CN1218472A (en)
AR (1) AR006520A1 (en)
AU (1) AU712141B2 (en)
BR (1) BR9708103A (en)
CA (1) CA2247814A1 (en)
CZ (1) CZ297798A3 (en)
EE (1) EE9800298A (en)
ID (1) ID16283A (en)
IL (1) IL126271A0 (en)
IS (1) IS4848A (en)
NO (1) NO984290L (en)
NZ (1) NZ331614A (en)
PL (1) PL328921A1 (en)
SK (1) SK118798A3 (en)
TR (1) TR199801861T2 (en)
WO (1) WO1997034893A1 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10110749A1 (en) * 2001-03-07 2002-09-12 Bayer Ag Substituted aminodicarboxylic acid derivatives
JP2003002863A (en) * 2001-06-25 2003-01-08 Nippon Soda Co Ltd Method for producing benzoic acids and novel compounds
SE0102404D0 (en) * 2001-07-04 2001-07-04 Active Biotech Ab Novel immunomodulating compounds
US6642249B2 (en) 2001-07-04 2003-11-04 Active Biotech Ab Immunomodulating compounds
DE10229762A1 (en) * 2002-07-03 2004-01-22 Aventis Pharma Deutschland Gmbh Pyrazoloisoquinoline derivatives for the inhibition of NFkappaB-inducing kinase
ATE353898T1 (en) * 2002-11-22 2007-03-15 Active Biotech Ab PYRAZOLOCHINOLINES WITH IMMUNOMODULATING EFFECTS
ATE425164T1 (en) 2002-12-16 2009-03-15 Active Biotech Ab TETRACYCLIC IMMUNOMODULATING COMPOUNDS
DK1603917T3 (en) 2003-03-14 2011-02-28 Medigene Ag Immunomodulating heterocyclic compounds
GB0325644D0 (en) 2003-11-04 2003-12-10 Avidex Ltd Immuno ihibitory pyrazolone compounds
SV2005001973A (en) 2003-12-12 2005-11-04 Wyeth Corp USEFUL KINOLINES IN THE TREATMENT OF CARDIOVASCULAR DISEASES REF. WYTH0090-504 (AM101500)
FR2870239B1 (en) * 2004-05-11 2006-06-16 Sanofi Synthelabo DERIVATIVES OF 2H- OR 3H-BENZO [E] INDAZOL-1-YLE CARBAMATE, THEIR PREPARATION AND THEIR THERAPEUTIC USE.
GB0411770D0 (en) * 2004-05-26 2004-06-30 Avidex Ltd Immuno inhibitory heterocyclic compouds
US7932253B2 (en) 2004-08-09 2011-04-26 Medigene Ag Immunomodulating oxopyrrazolocinnolines as CD80 inhibitors
HRP20120078T1 (en) 2006-10-31 2012-02-29 Pfizer Products Inc. Pyrazoline compounds as mineralocorticoid receptor antagonists
CN102372710A (en) 2010-08-18 2012-03-14 山东轩竹医药科技有限公司 Fused cyclic compound being taken as mineral corticoid recept antagonist
AU2012215741A1 (en) 2011-02-09 2013-08-22 Nissan Chemical Industries, Ltd. Pyrazole derivative and pest control agent
CA3111878A1 (en) * 2018-09-07 2020-03-12 Merck Patent Gmbh 5-morpholin-4-yl-pyrazolo[4,3-b]pyridine derivatives
WO2021257863A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Pyrrolotriazine compounds as jak2 v617f inhibitors
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
WO2022006457A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
US11767323B2 (en) 2020-07-02 2023-09-26 Incyte Corporation Tricyclic pyridone compounds as JAK2 V617F inhibitors
WO2022046989A1 (en) 2020-08-27 2022-03-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
US11919908B2 (en) 2020-12-21 2024-03-05 Incyte Corporation Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors
WO2022182839A1 (en) 2021-02-25 2022-09-01 Incyte Corporation Spirocyclic lactams as jak2 v617f inhibitors
JP2025509672A (en) 2022-03-17 2025-04-11 インサイト・コーポレイション Tricyclic urea compounds as JAK2 V617F inhibitors
CN119638634A (en) * 2023-09-18 2025-03-18 上海赛默罗生物科技有限公司 Cinnoline-2-oxide compounds and preparation methods and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524146A (en) * 1982-12-08 1985-06-18 Ciba-Geigy Corporation Certain -2-heterocycle substituted pyrazoloquinolines
JPS61112075A (en) * 1984-11-05 1986-05-30 Shionogi & Co Ltd Thienylpyrazoloquinoline derivative
SE8903564D0 (en) * 1989-10-26 1989-10-26 Pharmacia Ab NEW USE CONDENSED QUINOLINE COMPOUND
JPH05194515A (en) * 1991-07-31 1993-08-03 Kyowa Hakko Kogyo Co Ltd Condensed naphthyridine derivative

Also Published As

Publication number Publication date
SK118798A3 (en) 1999-03-12
EE9800298A (en) 1999-02-15
CN1218472A (en) 1999-06-02
BR9708103A (en) 1999-07-27
NO984290D0 (en) 1998-09-16
KR20000064716A (en) 2000-11-06
CZ297798A3 (en) 1999-03-17
PL328921A1 (en) 1999-03-01
ID16283A (en) 1997-09-18
AR006520A1 (en) 1999-09-08
JP2000506884A (en) 2000-06-06
AU2186797A (en) 1997-10-10
IL126271A0 (en) 1999-05-09
AU712141B2 (en) 1999-10-28
IS4848A (en) 1998-09-16
NO984290L (en) 1998-10-27
WO1997034893A1 (en) 1997-09-25
CA2247814A1 (en) 1997-09-25
NZ331614A (en) 2000-07-28
EP0888347A1 (en) 1999-01-07

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