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AU2018275122A1 - Dosing schedule for tesetaxel and capecitabine - Google Patents

Dosing schedule for tesetaxel and capecitabine Download PDF

Info

Publication number
AU2018275122A1
AU2018275122A1 AU2018275122A AU2018275122A AU2018275122A1 AU 2018275122 A1 AU2018275122 A1 AU 2018275122A1 AU 2018275122 A AU2018275122 A AU 2018275122A AU 2018275122 A AU2018275122 A AU 2018275122A AU 2018275122 A1 AU2018275122 A1 AU 2018275122A1
Authority
AU
Australia
Prior art keywords
capecitabine
day
administering
day cycle
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2018275122A
Other languages
English (en)
Inventor
Stew KROLL
John G. Lemkey
Steven Pfeiffer
Kevin Tang
Jeff VACIRCA
Thomas Wei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Odonate Inc
Original Assignee
Odonate Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Odonate Therapeutics Inc filed Critical Odonate Therapeutics Inc
Publication of AU2018275122A1 publication Critical patent/AU2018275122A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2018275122A 2017-06-02 2018-06-01 Dosing schedule for tesetaxel and capecitabine Abandoned AU2018275122A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762514483P 2017-06-02 2017-06-02
US62/514,483 2017-06-02
PCT/US2018/035653 WO2018223029A1 (fr) 2017-06-02 2018-06-01 Programme de dosage pour tésétaxel et capécitabine

Publications (1)

Publication Number Publication Date
AU2018275122A1 true AU2018275122A1 (en) 2019-12-19

Family

ID=64455637

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018275122A Abandoned AU2018275122A1 (en) 2017-06-02 2018-06-01 Dosing schedule for tesetaxel and capecitabine

Country Status (14)

Country Link
US (1) US20200179427A1 (fr)
EP (1) EP3630091A4 (fr)
JP (1) JP2020522568A (fr)
KR (1) KR20200014880A (fr)
CN (1) CN111032035A (fr)
AU (1) AU2018275122A1 (fr)
BR (1) BR112019025164A2 (fr)
CA (1) CA3065783A1 (fr)
EA (1) EA201992852A1 (fr)
IL (1) IL270973A (fr)
MA (1) MA50039A (fr)
MX (1) MX2019014489A (fr)
TW (1) TW201902473A (fr)
WO (1) WO2018223029A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202027739A (zh) * 2018-10-17 2020-08-01 美商蜻蛉治療股份有限公司 以替司他賽(tesetaxel)治療cns腫瘤之方法
WO2021034335A1 (fr) * 2019-08-16 2021-02-25 Odonate Therapeutics, Inc. Procédés d'administration de tésétaxel avec des glucocorticoïdes qui sont des inducteurs de cyp3a4

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201701880A (zh) * 2015-04-14 2017-01-16 莫瑞麥克製藥公司 改善持續釋放藥物治療之藥物動力學及治療指數之方法

Also Published As

Publication number Publication date
CN111032035A (zh) 2020-04-17
MX2019014489A (es) 2020-08-17
EA201992852A1 (ru) 2020-03-27
EP3630091A4 (fr) 2021-03-10
IL270973A (en) 2020-01-30
TW201902473A (zh) 2019-01-16
MA50039A (fr) 2020-07-08
US20200179427A1 (en) 2020-06-11
BR112019025164A2 (pt) 2020-06-16
CA3065783A1 (fr) 2018-12-06
KR20200014880A (ko) 2020-02-11
WO2018223029A1 (fr) 2018-12-06
JP2020522568A (ja) 2020-07-30
EP3630091A1 (fr) 2020-04-08

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period