AU2003300394A1 - In vivo methods for validating the role of a tumor maintenance gene - Google Patents

In vivo methods for validating the role of a tumor maintenance gene

Info

Publication number: AU2003300394A1
Authority: AU; Australia
Prior art keywords: validating; role; vivo methods; tumor maintenance; maintenance gene
Prior art date: 2002-12-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2003300394A

Other versions

AU2003300394A8 (en

Inventor

Steven C. Clark

Ronald Depinho

Joerg Heyer

Tyler Jacks

Ronan C. O'hagan

Anna Pavlova

William Rideout

Murray O. Robinson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aveo Pharmaceuticals Inc

Original Assignee

Genpath Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-24

Filing date

2003-12-23

Publication date

2004-07-22

2003-12-23 Application filed by Genpath Pharmaceuticals Inc filed Critical Genpath Pharmaceuticals Inc

2004-07-22 Publication of AU2003300394A1 publication Critical patent/AU2003300394A1/en

2004-07-22 Publication of AU2003300394A8 publication Critical patent/AU2003300394A8/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/12—Applications; Uses in screening processes in functional genomics, i.e. for the determination of gene function
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AU2003300394A 2002-12-24 2003-12-23 In vivo methods for validating the role of a tumor maintenance gene Abandoned AU2003300394A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US43649902P	2002-12-24	2002-12-24
US60/436,499		2002-12-24
US45480203P	2003-03-12	2003-03-12
US60/454,802		2003-03-12
PCT/US2003/041358 WO2004058948A2 (en)	2002-12-24	2003-12-23	In vivo methods for validating the role of a tumor maintenance gene

Publications (2)

Publication Number	Publication Date
AU2003300394A1 true AU2003300394A1 (en)	2004-07-22
AU2003300394A8 AU2003300394A8 (en)	2004-07-22

Family

ID=32685458

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2003300394A Abandoned AU2003300394A1 (en)	2002-12-24	2003-12-23	In vivo methods for validating the role of a tumor maintenance gene

Country Status (2)

Country	Link
AU (1)	AU2003300394A1 (en)
WO (1)	WO2004058948A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060222590A1 (en)	2005-04-05	2006-10-05	Murray Robinson	Directed complementation
CA2728575A1 (en)	2007-06-29	2009-01-08	Boston Biomedical, Inc.	Enabling the use of long dsrna for gene targeting in mammalian and other selected animal cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1068311B2 (en) *	1998-04-08	2020-12-09	Commonwealth Scientific and Industrial Research Organisation	Methods and means for obtaining modified phenotypes
HK1047109A1 (en) *	1999-10-15	2003-02-07	University Of Massachusetts	Rna interference pathway genes as tools for targeted genetic interference

2003
- 2003-12-23 AU AU2003300394A patent/AU2003300394A1/en not_active Abandoned
- 2003-12-23 WO PCT/US2003/041358 patent/WO2004058948A2/en not_active Ceased

Also Published As

Publication number	Publication date
WO2004058948A3 (en)	2004-10-14
AU2003300394A8 (en)	2004-07-22
WO2004058948A2 (en)	2004-07-15

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Legal Events

Date	Code	Title	Description
2005-09-22	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase