[go: up one dir, main page]

AU2003239197A1 - Novel stable anti-cd22 antibodies - Google Patents

Novel stable anti-cd22 antibodies

Info

Publication number
AU2003239197A1
AU2003239197A1 AU2003239197A AU2003239197A AU2003239197A1 AU 2003239197 A1 AU2003239197 A1 AU 2003239197A1 AU 2003239197 A AU2003239197 A AU 2003239197A AU 2003239197 A AU2003239197 A AU 2003239197A AU 2003239197 A1 AU2003239197 A1 AU 2003239197A1
Authority
AU
Australia
Prior art keywords
antibodies
stable anti
novel stable
novel
stable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003239197A
Other languages
English (en)
Other versions
AU2003239197A8 (en
Inventor
Michaela Arndt
Jurgen Krauss
Susanna Rybak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Government of the United States of America
Original Assignee
US Department of Health and Human Services
Government of the United States of America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, Government of the United States of America filed Critical US Department of Health and Human Services
Publication of AU2003239197A8 publication Critical patent/AU2003239197A8/xx
Publication of AU2003239197A1 publication Critical patent/AU2003239197A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624Disulfide-stabilized antibody (dsFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU2003239197A 2002-06-07 2003-06-09 Novel stable anti-cd22 antibodies Abandoned AU2003239197A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38730602P 2002-06-07 2002-06-07
US60/387,306 2002-06-07
PCT/US2003/018201 WO2003104425A2 (fr) 2002-06-07 2003-06-09 Nouveaux anticorps anti-cd22 stables

Publications (2)

Publication Number Publication Date
AU2003239197A8 AU2003239197A8 (en) 2003-12-22
AU2003239197A1 true AU2003239197A1 (en) 2003-12-22

Family

ID=29736288

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003239197A Abandoned AU2003239197A1 (en) 2002-06-07 2003-06-09 Novel stable anti-cd22 antibodies

Country Status (2)

Country Link
AU (1) AU2003239197A1 (fr)
WO (1) WO2003104425A2 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2342929T3 (es) 2001-09-26 2010-07-19 The Government of the United States of America as represented by the Secretary of Health and Human Anticuerpos anti-cd22 con afinidad aumentada por las celulas leucemicas que expresan cd22.
JPWO2004087763A1 (ja) * 2003-03-31 2006-07-27 中外製薬株式会社 Cd22に対する改変抗体およびその利用
ES2558338T3 (es) 2005-03-25 2016-02-03 National Research Council Of Canada Método para aislamiento de polipéptidos solubles
JP5620626B2 (ja) 2005-03-31 2014-11-05 中外製薬株式会社 会合制御によるポリペプチド製造方法
US9493569B2 (en) 2005-03-31 2016-11-15 Chugai Seiyaku Kabushiki Kaisha Structural isomers of sc(Fv)2
KR101360671B1 (ko) 2005-06-10 2014-02-07 추가이 세이야쿠 가부시키가이샤 sc(Fv)2를 함유하는 의약조성물
EP1908482B1 (fr) 2005-06-10 2017-09-06 Chugai Seiyaku Kabushiki Kaisha Stabilisant pour une préparation de protéine contenant de la méglumine et son utilisation
EP2009101B1 (fr) 2006-03-31 2017-10-25 Chugai Seiyaku Kabushiki Kaisha Procede de modification d'anticorps pour purifier un anticorps bispecifique
WO2014057118A1 (fr) * 2012-10-12 2014-04-17 Adc Therapeutics Sarl Conjugués anticorps anti-cd22 - pyrrolobenzodiazépine
ES2881306T3 (es) 2013-09-27 2021-11-29 Chugai Pharmaceutical Co Ltd Método para la producción de heteromultímeros de polipéptidos
JP7219005B2 (ja) 2015-12-28 2023-02-07 中外製薬株式会社 Fc領域含有ポリペプチドの精製を効率化するための方法
CN120535649A (zh) 2018-08-30 2025-08-26 免疫生物公司 单链嵌合多肽和其用途
CN112888445B (zh) 2018-08-30 2025-06-10 免疫生物公司 治疗老年化相关病症的方法
NZ772550A (en) 2018-08-30 2025-08-29 Immunitybio Inc Multi-chain chimeric polypeptides and uses thereof
KR20210152472A (ko) * 2019-03-11 2021-12-15 메모리얼 슬로안 케터링 캔서 센터 Cd22 항체 및 이를 사용하는 방법
KR20220035394A (ko) 2019-06-21 2022-03-22 에이치씨더블유 바이올로직스, 인크. 다중-사슬 키메라 폴리펩티드 및 이의 용도
AU2021220870A1 (en) 2020-02-11 2022-08-04 Immunitybio, Inc. Methods of treating age-related and inflammatory diseases
WO2021163298A1 (fr) 2020-02-11 2021-08-19 HCW Biologics, Inc. Méthodes d'activation de lymphocytes t régulateurs
KR20220140535A (ko) 2020-02-11 2022-10-18 에이치씨더블유 바이올로직스, 인크. 크로마토그래피 수지 및 이의 용도
CN115836087A (zh) 2020-04-29 2023-03-21 Hcw生物科技公司 抗cd26蛋白及其用途
US12024545B2 (en) 2020-06-01 2024-07-02 HCW Biologics, Inc. Methods of treating aging-related disorders
WO2021247003A1 (fr) 2020-06-01 2021-12-09 HCW Biologics, Inc. Méthodes de traitement de troubles liés au vieillissement
KR20230031280A (ko) 2020-06-01 2023-03-07 에이치씨더블유 바이올로직스, 인크. 노화 관련 장애의 치료 방법
JP2025508939A (ja) 2022-03-02 2025-04-10 イミュニティーバイオ インコーポレイテッド 膵臓癌の治療方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9709421D0 (en) * 1997-05-10 1997-07-02 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
WO2003104425A2 (fr) 2003-12-18
WO2003104425A3 (fr) 2005-02-17
AU2003239197A8 (en) 2003-12-22

Similar Documents

Publication Publication Date Title
AU2003219277A1 (en) Intracellular antibodies
AU2003239197A1 (en) Novel stable anti-cd22 antibodies
AU2003217912A1 (en) Antibody optimization
AU2003239909A1 (en) Enhanced-service provision
AU2002335152A1 (en) Robot-phone
AU2003275546A1 (en) Heat-schrinkable film
AU2002367810A1 (en) Bis-transition-metal-chelate-probes
AU2002368348A1 (en) Electrosomatogram
AU2002318053A1 (en) Suplier
AU2002950855A0 (en) Materials
AU2002348964A1 (en) Snowbike
AU2002341221A1 (en) Honey-brandy
AU2002344387A1 (en) Multifunction-pillow
HK1087130A (en) Antibodies
AU2002100957A4 (en) Sluggit
AU2002100160A4 (en) Oxidirator
AU2002100508A4 (en) Photocard
AU2002100510A4 (en) Bottlenecker
AU2002100541A4 (en) Backmate
AU2002100602A4 (en) Bonsystem
AU2002100655A4 (en) Armamulch
AU2002100739A4 (en) Neuramax
AU2002100747A4 (en) Powersell
AU2002100482A4 (en) Tail-gate-ezy
AU2002100026A4 (en) Disc400

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase