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AU2003219291A1 - Bicyclic compounds useful as angiotensin ii agonists - Google Patents

Bicyclic compounds useful as angiotensin ii agonists

Info

Publication number
AU2003219291A1
AU2003219291A1 AU2003219291A AU2003219291A AU2003219291A1 AU 2003219291 A1 AU2003219291 A1 AU 2003219291A1 AU 2003219291 A AU2003219291 A AU 2003219291A AU 2003219291 A AU2003219291 A AU 2003219291A AU 2003219291 A1 AU2003219291 A1 AU 2003219291A1
Authority
AU
Australia
Prior art keywords
angiotensin
agonists
compounds useful
bicyclic compounds
bicyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003219291A
Inventor
Mathias Alterman
Anders Hallberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vicore Pharma AB
Original Assignee
Vicore Pharma AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vicore Pharma AB filed Critical Vicore Pharma AB
Publication of AU2003219291A1 publication Critical patent/AU2003219291A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/34Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003219291A 2003-03-24 2003-03-24 Bicyclic compounds useful as angiotensin ii agonists Abandoned AU2003219291A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2003/001251 WO2004085420A1 (en) 2003-03-24 2003-03-24 Bicyclic compounds useful as angiotensin ii agonists

Publications (1)

Publication Number Publication Date
AU2003219291A1 true AU2003219291A1 (en) 2004-10-18

Family

ID=33042165

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003219291A Abandoned AU2003219291A1 (en) 2003-03-24 2003-03-24 Bicyclic compounds useful as angiotensin ii agonists

Country Status (2)

Country Link
AU (1) AU2003219291A1 (en)
WO (1) WO2004085420A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8067418B2 (en) 2005-04-12 2011-11-29 Vicore Pharma Ab Tricyclic angiotensin II agonists
ES2395194T3 (en) 2005-04-12 2013-02-11 Vicore Pharma Ab New tricyclic agonists of angiotensin II
JP5179349B2 (en) * 2005-04-12 2013-04-10 ヴィコール・ファルマ・アーベー Novel bicyclic angiotensin II agonist
CA2690226C (en) 2007-06-20 2012-07-24 Mitsubishi Tanabe Pharma Corporation Novel malonic acid sulfonamide derivative and pharmaceutical use thereof
ES2974690T3 (en) 2010-11-05 2024-07-01 Firmenich Incorporated Useful compounds as TRPM8 modulators
WO2015152393A1 (en) 2014-04-03 2015-10-08 国立研究開発法人国立循環器病研究センター Medicine for suppressing malignant tumor metastasis
TW202140422A (en) 2014-10-06 2021-11-01 美商維泰克斯製藥公司 Modulators of cystic fibrosis transmembrane conductance regulator
WO2016107879A2 (en) * 2014-12-30 2016-07-07 Vicore Pharma Ab New use of angiotensin ii receptor agonists
MX389514B (en) 2015-10-01 2025-03-20 Firmenich Incorporated COMPOUNDS USEFUL AS TRANSIENT MELASTATIN POTENTIAL 8 RECEPTOR CHANNEL (TRPM8) MODULATORS.
ES2946970T3 (en) 2016-03-31 2023-07-28 Vertex Pharma Transmembrane conductance regulator of cystic fibrosis modulators
BR112019006213A2 (en) 2016-09-30 2019-06-18 Vertex Pharma cystic fibrosis transmembrane conductance regulator modulator, pharmaceutical compositions, treatment methods and process for making the modulator
LT3551622T (en) 2016-12-09 2021-02-25 Vertex Pharmaceuticals Incorporated Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
MA54105A (en) 2017-06-08 2021-09-15 Vertex Pharma CYSTIC FIBROSIS TREATMENT METHODS
WO2019018395A1 (en) 2017-07-17 2019-01-24 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
CA3071278A1 (en) 2017-08-02 2019-02-07 Vertex Pharmaceuticals Incorporated Processes for preparing pyrrolidine compounds
TWI719349B (en) 2017-10-19 2021-02-21 美商維泰克斯製藥公司 Crystalline forms and compositions of cftr modulators
WO2019113476A2 (en) 2017-12-08 2019-06-13 Vertex Pharmaceuticals Incorporated Processes for making modulators of cystic fibrosis transmembrane conductance regulator
TWI810243B (en) 2018-02-05 2023-08-01 美商維泰克斯製藥公司 Pharmaceutical compositions for treating cystic fibrosis
US11414439B2 (en) 2018-04-13 2022-08-16 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU78601A (en) * 1999-05-05 2005-07-19 Aventis Pharma Deutschland Gmbh. 1-(p-thienylbenzyl)-imidazoles as angiotensin-(1-7) receptor agonists, method for the production and the utilization thereof and pharmaceutical preparations containing said compounds
CA2395088A1 (en) * 1999-12-15 2001-06-21 Bristol-Myers Squibb Company Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
DE10112041A1 (en) * 2001-03-14 2002-09-26 Aventis Pharma Gmbh p-Thienylbenzylamides as agonists of angiotensin (1-7) receptors, processes for their preparation, their use and pharmaceutical compositions containing them
WO2002096883A1 (en) * 2001-05-31 2002-12-05 Vicore Pharma Ab Tricyclic compounds useful as angiotensin ii agonists

Also Published As

Publication number Publication date
WO2004085420A1 (en) 2004-10-07

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