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AU2003217575A8 - Detection of molecular interaction by reactivation of an auto-inhibited responder (rair) - Google Patents

Detection of molecular interaction by reactivation of an auto-inhibited responder (rair)

Info

Publication number
AU2003217575A8
AU2003217575A8 AU2003217575A AU2003217575A AU2003217575A8 AU 2003217575 A8 AU2003217575 A8 AU 2003217575A8 AU 2003217575 A AU2003217575 A AU 2003217575A AU 2003217575 A AU2003217575 A AU 2003217575A AU 2003217575 A8 AU2003217575 A8 AU 2003217575A8
Authority
AU
Australia
Prior art keywords
rair
reactivation
auto
detection
molecular interaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003217575A
Other versions
AU2003217575A1 (en
Inventor
Jeng-Horng Her
Robert R Balint
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Humanigen Inc
Original Assignee
Kalobios Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/076,845 external-priority patent/US20030157579A1/en
Priority claimed from US10/208,730 external-priority patent/US7335478B2/en
Application filed by Kalobios Inc filed Critical Kalobios Inc
Publication of AU2003217575A8 publication Critical patent/AU2003217575A8/en
Publication of AU2003217575A1 publication Critical patent/AU2003217575A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2003217575A 2002-02-14 2003-02-14 Detection of molecular interaction by reactivation of an auto-inhibited responder (rair) Abandoned AU2003217575A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US10/076,845 US20030157579A1 (en) 2002-02-14 2002-02-14 Molecular sensors activated by disinhibition
US10/076,845 2002-02-14
US37380202P 2002-04-18 2002-04-18
US37376502P 2002-04-18 2002-04-18
US60/373,765 2002-04-18
US60/373,802 2002-04-18
US37971802P 2002-05-10 2002-05-10
US60/379,718 2002-05-10
US10/208,730 2002-07-29
US10/208,730 US7335478B2 (en) 2002-04-18 2002-07-29 Reactivation-based molecular interaction sensors
PCT/US2003/004925 WO2003068945A2 (en) 2002-02-14 2003-02-14 Detection of molecular interaction by reactivation of an auto-inhibited responder (rair)

Publications (2)

Publication Number Publication Date
AU2003217575A8 true AU2003217575A8 (en) 2003-09-04
AU2003217575A1 AU2003217575A1 (en) 2003-09-04

Family

ID=27739444

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003217575A Abandoned AU2003217575A1 (en) 2002-02-14 2003-02-14 Detection of molecular interaction by reactivation of an auto-inhibited responder (rair)

Country Status (3)

Country Link
EP (1) EP1570073A4 (en)
AU (1) AU2003217575A1 (en)
WO (1) WO2003068945A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG193534A1 (en) * 2011-03-23 2013-10-30 Agency Science Tech & Res Recombinant protein biosensors and a method for detecting the presence of an analyte molecule
EP3213073A4 (en) * 2014-10-27 2018-10-24 The University Of Queensland Bimolecular autoinhibited biosensor
WO2018090094A1 (en) * 2016-11-16 2018-05-24 Universal Biosensors Pty Ltd Cleavage event transduction methods and products

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342345B1 (en) * 1997-04-02 2002-01-29 The Board Of Trustees Of The Leland Stanford Junior University Detection of molecular interactions by reporter subunit complementation

Also Published As

Publication number Publication date
WO2003068945A2 (en) 2003-08-21
WO2003068945A3 (en) 2005-07-14
EP1570073A2 (en) 2005-09-07
AU2003217575A1 (en) 2003-09-04
EP1570073A4 (en) 2006-01-18

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase