[go: up one dir, main page]

AU2003210296A1 - Process for the preparation of 4-hetero-substituted phenylalanine derivatives - Google Patents

Process for the preparation of 4-hetero-substituted phenylalanine derivatives

Info

Publication number
AU2003210296A1
AU2003210296A1 AU2003210296A AU2003210296A AU2003210296A1 AU 2003210296 A1 AU2003210296 A1 AU 2003210296A1 AU 2003210296 A AU2003210296 A AU 2003210296A AU 2003210296 A AU2003210296 A AU 2003210296A AU 2003210296 A1 AU2003210296 A1 AU 2003210296A1
Authority
AU
Australia
Prior art keywords
hetero
preparation
phenylalanine derivatives
substituted phenylalanine
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003210296A
Other versions
AU2003210296A8 (en
Inventor
Jason William Beames Cooke
Douglas Hayes
Richard Anthony Henson
Stephen Andrew Hermitage
Richard Anthony Ward
Andrew Jonathan Whitehead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU2003210296A1 publication Critical patent/AU2003210296A1/en
Publication of AU2003210296A8 publication Critical patent/AU2003210296A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2003210296A 2002-02-15 2003-02-14 Process for the preparation of 4-hetero-substituted phenylalanine derivatives Abandoned AU2003210296A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0203665.5 2002-02-15
GBGB0203665.5A GB0203665D0 (en) 2002-02-15 2002-02-15 Process
PCT/EP2003/001607 WO2003068725A2 (en) 2002-02-15 2003-02-14 Process for the preparation of 4-hetero-substituted phenylalanine derivatives

Publications (2)

Publication Number Publication Date
AU2003210296A1 true AU2003210296A1 (en) 2003-09-04
AU2003210296A8 AU2003210296A8 (en) 2003-09-04

Family

ID=9931182

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003210296A Abandoned AU2003210296A1 (en) 2002-02-15 2003-02-14 Process for the preparation of 4-hetero-substituted phenylalanine derivatives

Country Status (5)

Country Link
EP (1) EP1474405A2 (en)
JP (1) JP2005517703A (en)
AU (1) AU2003210296A1 (en)
GB (1) GB0203665D0 (en)
WO (1) WO2003068725A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0213122D0 (en) * 2002-06-07 2002-07-17 Glaxo Group Ltd Compounds
JP2020193181A (en) * 2019-05-30 2020-12-03 東ソー株式会社 Method for producing aromatic nitrile compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277737B1 (en) * 1995-12-28 1997-11-12 Zambon Spa TIOLIC DERIVATIVES FOR METALLOPEPTIDASE INHIBITIVE ACTIVITY

Also Published As

Publication number Publication date
JP2005517703A (en) 2005-06-16
WO2003068725A3 (en) 2003-12-24
GB0203665D0 (en) 2002-04-03
EP1474405A2 (en) 2004-11-10
AU2003210296A8 (en) 2003-09-04
WO2003068725A2 (en) 2003-08-21

Similar Documents

Publication Publication Date Title
AU2003224760A1 (en) Process for the preparation of antiviral 7-azaindole derivatives
AU2002307805A1 (en) Process for the preparation of cefdinir
AU2003235951A1 (en) Process for the preparation of 2-aminopyrazine derivatives
AU2003260983A1 (en) Processes for the preparation of s-(-)-amlodipine
AU2003263622A1 (en) Process for preparing prostaglandin derivatives and starting materials for the same
AU2003218704A1 (en) Process for preparing 2-aminoindan derivatives
AU2003252467A1 (en) Process for preparation of 1,3-benzodioxole-2-spiro- cycloalkane derivatives
AU2003245880A1 (en) Process for the preparation of thioalkylamine derivatives
AU2002367890A1 (en) Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate
AU2003253326A1 (en) Method for the production of phenylalanine derivatives
AU2003225426A1 (en) Process for the preparation of urea
AU2003229459A1 (en) Methods of using thiazolidinedithione derivatives
IL165802A0 (en) Process for the preparation of phenylalanine enamide derivatives
AU2003278420A1 (en) Process for the preparation of ganciclovir
AU2002359034A1 (en) Process for the preparation of simvastatin
AU2003260942A1 (en) A process for the preparation of oxindole derivatives
IL162770A (en) Process for the preparation of 7??-methyl-estr-4-ene-3-one derivatives
AU2003256006A1 (en) Improved process for preparation of risperidone
AU2003210296A1 (en) Process for the preparation of 4-hetero-substituted phenylalanine derivatives
AU2003219507A1 (en) Process for the preparation of highly pure torsemide
EP1386911A3 (en) Process for the preparation of acyloxybenzenesulfonates
AU2003235129A1 (en) Process for preparation of 2-aminoketones
HK1073646A (en) Process for the preparation of phenylalanine enamide derivatives
AU2003246365A1 (en) Process for the preparation of acyloxysilanes
AU2003221404A1 (en) PROCESS FOR PREPARATION OF trans-4-AMINOCYCLOHEXANE- CARBOXYLIC ACIDS

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase