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AU2003254333A1 - Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect - Google Patents

Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect

Info

Publication number
AU2003254333A1
AU2003254333A1 AU2003254333A AU2003254333A AU2003254333A1 AU 2003254333 A1 AU2003254333 A1 AU 2003254333A1 AU 2003254333 A AU2003254333 A AU 2003254333A AU 2003254333 A AU2003254333 A AU 2003254333A AU 2003254333 A1 AU2003254333 A1 AU 2003254333A1
Authority
AU
Australia
Prior art keywords
biodegradable
systems
active ingredients
shape memory
memory effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003254333A
Inventor
Andreas Lendlein
Susi Steuer
Annika Tuleweit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MnemoScience GmbH
Original Assignee
MnemoScience GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MnemoScience GmbH filed Critical MnemoScience GmbH
Publication of AU2003254333A1 publication Critical patent/AU2003254333A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/16—Materials with shape-memory or superelastic properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
AU2003254333A 2002-07-10 2003-07-10 Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect Abandoned AU2003254333A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US39516702P 2002-07-10 2002-07-10
US60/395,167 2002-07-10
US21840802P 2002-07-14 2002-07-14
US60/218,408 2002-07-14
US21876002P 2002-07-17 2002-07-17
US60/218,760 2002-07-17
PCT/EP2003/007515 WO2004006885A2 (en) 2002-07-10 2003-07-10 Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect

Publications (1)

Publication Number Publication Date
AU2003254333A1 true AU2003254333A1 (en) 2004-02-02

Family

ID=30119045

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003254333A Abandoned AU2003254333A1 (en) 2002-07-10 2003-07-10 Systems for releasing active ingredients, based on biodegradable or biocompatible polymers with a shape memory effect

Country Status (4)

Country Link
EP (1) EP1519713B1 (en)
AU (1) AU2003254333A1 (en)
DK (1) DK1519713T3 (en)
WO (1) WO2004006885A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7524914B2 (en) 2002-10-11 2009-04-28 The University Of Connecticut Shape memory polymers based on semicrystalline thermoplastic polyurethanes bearing nanostructured hard segments
US7794494B2 (en) 2002-10-11 2010-09-14 Boston Scientific Scimed, Inc. Implantable medical devices
CA2501549C (en) 2002-10-11 2011-08-30 University Of Connecticut Blends of amorphous and semicrystalline polymers having shape memory properties
JP4960631B2 (en) 2002-10-11 2012-06-27 ユニバーシティ オブ コネチカット Shape memory polymers based on semi-crystalline thermoplastic polyurethane with nanostructured hard segments
US7976936B2 (en) 2002-10-11 2011-07-12 University Of Connecticut Endoprostheses
WO2004033553A1 (en) 2002-10-11 2004-04-22 University Of Connecticut Crosslinked polycyclooctene
WO2004110515A1 (en) * 2003-06-13 2004-12-23 Mnemoscience Gmbh Biodegradable stents
DE102004031014A1 (en) * 2004-06-26 2006-01-12 Raumedic Ag Device for targeted liberation of substances in a cavity
US8043361B2 (en) 2004-12-10 2011-10-25 Boston Scientific Scimed, Inc. Implantable medical devices, and methods of delivering the same
US20080228186A1 (en) * 2005-04-01 2008-09-18 The Regents Of The University Of Colorado Graft Fixation Device
GB0603704D0 (en) * 2006-02-24 2006-04-05 Depuy Int Ltd Implant coating
US7557167B2 (en) * 2006-09-28 2009-07-07 Gore Enterprise Holdings, Inc. Polyester compositions, methods of manufacturing said compositions, and articles made therefrom
DE102007059755A1 (en) 2007-12-10 2009-06-18 Biotronik Vi Patent Ag Implants with membrane diffusion controlled drug release
EP2075272A1 (en) 2007-12-28 2009-07-01 Mnemoscience GmbH Shape memory polymer networks from crosslinkable thermoplasts
EP2075273A1 (en) 2007-12-28 2009-07-01 Mnemoscience GmbH Multiple shape memory polymer networks
EP2075279A1 (en) 2007-12-28 2009-07-01 Mnemoscience GmbH Production of shape memory polymer articles by molding processes
EP2320962A2 (en) 2008-07-31 2011-05-18 Boston Scientific Scimed, Inc. Medical devices for therapeutic agent delivery
DE102009027151A1 (en) * 2009-06-24 2010-12-30 Gkss-Forschungszentrum Geesthacht Gmbh Particles with inducible shape change
US8221396B2 (en) 2009-08-27 2012-07-17 Silver Bullet Therapeutics, Inc. Bone implants for the treatment of infection
US9114197B1 (en) 2014-06-11 2015-08-25 Silver Bullett Therapeutics, Inc. Coatings for the controllable release of antimicrobial metal ions
US8927004B1 (en) 2014-06-11 2015-01-06 Silver Bullet Therapeutics, Inc. Bioabsorbable substrates and systems that controllably release antimicrobial metal ions
US10265435B2 (en) 2009-08-27 2019-04-23 Silver Bullet Therapeutics, Inc. Bone implant and systems and coatings for the controllable release of antimicrobial metal ions
US9821094B2 (en) 2014-06-11 2017-11-21 Silver Bullet Therapeutics, Inc. Coatings for the controllable release of antimicrobial metal ions
WO2011144257A1 (en) * 2010-05-21 2011-11-24 Rijksuniversiteit Groningen Amorphous resorbable polymeric network materials with shape memory
WO2012064402A1 (en) 2010-11-12 2012-05-18 Silver Bullet Therapeutics, Inc. Bone implant and systems that controllably releases silver
US9452242B2 (en) 2014-06-11 2016-09-27 Silver Bullet Therapeutics, Inc. Enhancement of antimicrobial silver, silver coatings, or silver platings
DE102023122214A1 (en) * 2023-08-18 2025-02-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Delivery device for the administration of therapeutic agents with a carrier made of shape memory polymers and method for their production

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE124072T1 (en) * 1985-01-04 1995-07-15 Thoratec Lab Corp METHOD FOR PRODUCING A MOLDED PART WITH SHAPE MEMORY PROPERTIES AND SOME OF THESE MOLDED PARTS OBTAINED.
JPH03163011A (en) * 1989-08-31 1991-07-15 Yamanouchi Pharmaceut Co Ltd Device stayed in stomach
US6241691B1 (en) * 1997-12-05 2001-06-05 Micrus Corporation Coated superelastic stent
AU751861B2 (en) * 1998-02-23 2002-08-29 Massachusetts Institute Of Technology Biodegradable shape memory polymers
AU758800B2 (en) * 1998-02-23 2003-03-27 Gkss-Forschungszentrum Geesthacht Gmbh Shape memory polymers
AU763085B2 (en) * 1998-11-12 2003-07-10 Takiron Co. Ltd. Shape-memory, biodegradable and absorbable material
WO2002041929A1 (en) * 2000-11-21 2002-05-30 Schering Ag Tubular vascular implants (stents) and methods for producing the same
US20030153972A1 (en) * 2002-02-14 2003-08-14 Michael Helmus Biodegradable implantable or insertable medical devices with controlled change of physical properties leading to biomechanical compatibility

Also Published As

Publication number Publication date
EP1519713A2 (en) 2005-04-06
WO2004006885A2 (en) 2004-01-22
WO2004006885A3 (en) 2004-03-18
EP1519713B1 (en) 2010-09-15
DK1519713T3 (en) 2011-01-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase