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AU2003267540A1 - Biodegradable polymer - Google Patents

Biodegradable polymer

Info

Publication number
AU2003267540A1
AU2003267540A1 AU2003267540A AU2003267540A AU2003267540A1 AU 2003267540 A1 AU2003267540 A1 AU 2003267540A1 AU 2003267540 A AU2003267540 A AU 2003267540A AU 2003267540 A AU2003267540 A AU 2003267540A AU 2003267540 A1 AU2003267540 A1 AU 2003267540A1
Authority
AU
Australia
Prior art keywords
biodegradable polymer
biodegradable
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003267540A
Other versions
AU2003267540A8 (en
Inventor
Jonathan Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIRUS PHARMACEUTICALS Ltd
Original Assignee
SIRUS PHARMACEUTICALS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0218827.4A external-priority patent/GB0218827D0/en
Priority claimed from GB0218828A external-priority patent/GB0218828D0/en
Priority claimed from GBGB0218830.8A external-priority patent/GB0218830D0/en
Priority claimed from GB0218831A external-priority patent/GB0218831D0/en
Priority claimed from GB0218829A external-priority patent/GB0218829D0/en
Priority claimed from GB0306445A external-priority patent/GB0306445D0/en
Application filed by SIRUS PHARMACEUTICALS Ltd filed Critical SIRUS PHARMACEUTICALS Ltd
Publication of AU2003267540A1 publication Critical patent/AU2003267540A1/en
Publication of AU2003267540A8 publication Critical patent/AU2003267540A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/44—Polyester-amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C08G73/1092—Polysuccinimides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2003267540A 2002-08-13 2003-08-13 Biodegradable polymer Abandoned AU2003267540A1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB0218830.8 2002-08-13
GBGB0218827.4A GB0218827D0 (en) 2002-08-13 2002-08-13 Anaesthetic compounds and conjugates thereof
GB0218828.2 2002-08-13
GB0218828A GB0218828D0 (en) 2002-08-13 2002-08-13 Anaesthetic conjugate for international delivery
GBGB0218830.8A GB0218830D0 (en) 2002-08-13 2002-08-13 Anaesthetic conjugate
GB0218831.6 2002-08-13
GB0218831A GB0218831D0 (en) 2002-08-13 2002-08-13 Biodegradable polymer
GB0218829.0 2002-08-13
GB0218827.4 2002-08-13
GB0218829A GB0218829D0 (en) 2002-08-13 2002-08-13 Anaesthetic compounds and conjugates thereof
GB0306445A GB0306445D0 (en) 2003-03-20 2003-03-20 Conjugate
GB0306445.8 2003-03-20
PCT/GB2003/003522 WO2004014973A2 (en) 2002-08-13 2003-08-13 Biodegradable polymer

Publications (2)

Publication Number Publication Date
AU2003267540A1 true AU2003267540A1 (en) 2004-02-25
AU2003267540A8 AU2003267540A8 (en) 2004-02-25

Family

ID=31721885

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003267540A Abandoned AU2003267540A1 (en) 2002-08-13 2003-08-13 Biodegradable polymer

Country Status (2)

Country Link
AU (1) AU2003267540A1 (en)
WO (1) WO2004014973A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0218830D0 (en) * 2002-08-13 2002-09-18 Syngenix Ltd Anaesthetic conjugate
WO2004082585A2 (en) * 2003-03-20 2004-09-30 Sirus Pharmaceuticals Ltd Water-soluble conjugates of phenytoin
EP1729814A2 (en) * 2004-04-01 2006-12-13 Cardiome Pharma Corp. Pegylated ion channel modulating compounds
US7705036B2 (en) 2004-04-01 2010-04-27 Cardiome Pharma Corp. Deuterated aminocyclohexyl ether compounds and processes for preparing same
CA2561819A1 (en) 2004-04-01 2005-12-01 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
JP5159314B2 (en) 2004-11-18 2013-03-06 カーディオム ファーマ コーポレイション Method for synthesizing aminocyclohexyl ether compound
JP5159616B2 (en) 2005-06-15 2013-03-06 カーディオム ファーマ コーポレイション Synthetic process for the preparation of aminocyclohexyl ether compounds
WO2010040187A1 (en) * 2008-10-10 2010-04-15 The Bionic Ear Institute Polymer-bioactive agent conjugates
US8535655B2 (en) 2008-10-10 2013-09-17 Polyactiva Pty Ltd. Biodegradable polymer—bioactive moiety conjugates
CN102245214B (en) * 2008-10-10 2014-10-29 波利艾克蒂瓦有限公司 Biodegradable polymer-bioactive moiety conjugates
CN116947836A (en) * 2017-04-26 2023-10-27 巴斯利尔药物国际股份公司 Method for preparing furazanobenzimidazole and crystal forms thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5372807A (en) * 1990-05-14 1994-12-13 University Of Medicine And Dentistry Of New Jersey Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use
WO1992000748A1 (en) * 1990-07-06 1992-01-23 Enzon, Inc. Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
EP0665729B1 (en) * 1992-09-04 2003-05-07 The General Hospital Corporation Biocompatible polymers containing diagnostic or therapeutic moieties
WO1996000079A1 (en) * 1994-06-27 1996-01-04 The General Hospital Corporation Graft co-polymer adducts of platinum (ii) compounds
US6284246B1 (en) * 1997-07-30 2001-09-04 The Procter & Gamble Co. Modified polypeptides with high activity and reduced allergenicity
EP1246608A4 (en) * 2000-01-05 2005-05-18 Imarx Therapeutics Inc Pharmaceutical formulations for the delivery of drugs having low aqueous solubility
US20020041898A1 (en) * 2000-01-05 2002-04-11 Unger Evan C. Novel targeted delivery systems for bioactive agents
US20030207247A1 (en) * 2001-12-05 2003-11-06 Cerus Corporation Preparation of red blood cells having reduced immunogenicity
GB0218830D0 (en) * 2002-08-13 2002-09-18 Syngenix Ltd Anaesthetic conjugate
GB0218827D0 (en) * 2002-08-13 2002-09-18 Syngenix Ltd Anaesthetic compounds and conjugates thereof

Also Published As

Publication number Publication date
WO2004014973A3 (en) 2004-09-23
WO2004014973A2 (en) 2004-02-19
AU2003267540A8 (en) 2004-02-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase