AU2002349001A1 - Pharmaceutical containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol and providing delayed release of the active ingredient - Google Patents
Pharmaceutical containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol and providing delayed release of the active ingredientInfo
- Publication number
- AU2002349001A1 AU2002349001A1 AU2002349001A AU2002349001A AU2002349001A1 AU 2002349001 A1 AU2002349001 A1 AU 2002349001A1 AU 2002349001 A AU2002349001 A AU 2002349001A AU 2002349001 A AU2002349001 A AU 2002349001A AU 2002349001 A1 AU2002349001 A1 AU 2002349001A1
- Authority
- AU
- Australia
- Prior art keywords
- dimethylamino
- phenol
- propyl
- ethyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KWTWDQCKEHXFFR-UHFFFAOYSA-N 3-[1-(dimethylamino)-2-methylpentan-3-yl]phenol Chemical compound CN(C)CC(C)C(CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-UHFFFAOYSA-N 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 230000003111 delayed effect Effects 0.000 title 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10152469.2 | 2001-10-24 | ||
| DE10152469A DE10152469A1 (en) | 2001-10-24 | 2001-10-24 | Delayed release analgesic formulations, comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol in hydrophilic or hydrophobic polymer matrix |
| DE10248309.4 | 2002-10-16 | ||
| DE2002148309 DE10248309A1 (en) | 2002-10-16 | 2002-10-16 | Delayed release analgesic formulations, comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol in hydrophilic or hydrophobic polymer matrix |
| PCT/EP2002/011809 WO2003035053A1 (en) | 2001-10-24 | 2002-10-22 | Pharmaceutical containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol and providing delayed release of the active ingredient |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2002349001B2 AU2002349001B2 (en) | 2003-05-06 |
| AU2002349001A1 true AU2002349001A1 (en) | 2003-07-03 |
| AU2002349001C1 AU2002349001C1 (en) | 2022-04-14 |
Family
ID=26010444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002349001A Active 2026-01-19 AU2002349001C1 (en) | 2001-10-24 | 2002-10-22 | Pharmaceutical containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol and providing delayed release of the active ingredient |
Country Status (28)
| Country | Link |
|---|---|
| US (7) | US20050058706A1 (en) |
| EP (1) | EP1439829B1 (en) |
| JP (2) | JP4758064B2 (en) |
| KR (1) | KR100958045B1 (en) |
| CN (1) | CN100402021C (en) |
| AR (1) | AR036943A1 (en) |
| AT (1) | ATE303802T1 (en) |
| AU (1) | AU2002349001C1 (en) |
| BR (1) | BRPI0213653B8 (en) |
| CA (1) | CA2464578C (en) |
| CO (1) | CO5570662A2 (en) |
| CY (1) | CY2012022I1 (en) |
| DE (1) | DE50204198D1 (en) |
| DK (1) | DK1439829T3 (en) |
| EC (1) | ECSP045102A (en) |
| ES (1) | ES2248622T3 (en) |
| HU (1) | HU230161B1 (en) |
| IL (2) | IL161587A0 (en) |
| MX (1) | MXPA04003742A (en) |
| MY (1) | MY127797A (en) |
| NO (2) | NO331896B1 (en) |
| NZ (1) | NZ532999A (en) |
| PE (1) | PE20030527A1 (en) |
| PL (1) | PL216535B1 (en) |
| PT (1) | PT1439829E (en) |
| SI (1) | SI1439829T1 (en) |
| WO (2) | WO2003035053A1 (en) |
| ZA (1) | ZA200403928B (en) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| EP1562567B1 (en) | 2002-11-22 | 2017-06-14 | Grünenthal GmbH | Combination of selected analgesics and cox-ii inhibitors |
| DE10336400A1 (en) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Anti-abuse dosage form |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE102004020220A1 (en) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Process for the preparation of a secured against misuse, solid dosage form |
| DE10361596A1 (en) * | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Process for producing an anti-abuse dosage form |
| DE102004032051A1 (en) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Process for the preparation of a secured against misuse, solid dosage form |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| ES2289542T3 (en) * | 2003-08-06 | 2008-02-01 | Grunenthal Gmbh | PHARMACEUTICAL FORM PROTECTED AGAINST POSSIBLE ABUSE. |
| DE102005005446A1 (en) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Break-resistant dosage forms with sustained release |
| DE602004007905T2 (en) | 2004-06-28 | 2008-05-08 | Grünenthal GmbH | Crystalline forms of (-) - (1R, 2R) -3- (3-dimethylamino-1-ethyl-2-methylpropyl) -phenol hydrochloride |
| JP5700904B2 (en) * | 2004-07-01 | 2015-04-15 | グリューネンタール・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Abuse prevention oral dosage form containing (1R, 2R) -3- (3-dimethylamino-1-ethyl-2-methyl-propyl) phenol |
| DE102004032103A1 (en) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Anti-abuse, oral dosage form |
| DE102004032049A1 (en) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Anti-abuse, oral dosage form |
| DE102005005449A1 (en) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Process for producing an anti-abuse dosage form |
| EP2012764B1 (en) * | 2006-04-28 | 2011-01-12 | Grünenthal GmbH | Pharmaceutical combination comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol |
| PT2012763E (en) * | 2006-04-28 | 2011-04-29 | Gruenenthal Gmbh | PHARMACEUTICAL COMBINATION COMPOSING 3- (3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL) PHENOL AND A NSAID |
| CN101091725A (en) * | 2006-06-23 | 2007-12-26 | 天津天士力制药股份有限公司 | Chinese traditional medicine grains and preparation method |
| SA07280459B1 (en) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | Tamper Resistant Oral Pharmaceutical Dosage Forms Comprising an Opioid Analgesic |
| DE102007011485A1 (en) * | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Dosage form with more difficult abuse |
| EP1985292A1 (en) * | 2007-04-23 | 2008-10-29 | Grünenthal GmbH | Titration of tapentadol |
| DE102007019417A1 (en) | 2007-04-23 | 2008-11-13 | Grünenthal GmbH | Tapentadol for the treatment of pain in osteoarthritis |
| KR101607112B1 (en) * | 2007-11-23 | 2016-03-29 | 그뤼넨탈 게엠베하 | Tapentadol compositions |
| PT2240431T (en) * | 2007-12-07 | 2017-05-03 | Gruenenthal Gmbh | Crystalline modifications of (1r, 2r)-3-(3-dimenthyl amino-1-ethyl-2-methyl-propyl) phenol |
| US8383152B2 (en) | 2008-01-25 | 2013-02-26 | Gruenenthal Gmbh | Pharmaceutical dosage form |
| TWI524904B (en) | 2008-05-09 | 2016-03-11 | 歌林達股份有限公司 | Process for the preparation of a solid dosage form, in particular a tablet, for pharmaceutical use and process for the preparation of a precursor for a solid dosage form, in particular a tablet |
| US20100190752A1 (en) | 2008-09-05 | 2010-07-29 | Gruenenthal Gmbh | Pharmaceutical Combination |
| ES2758831T3 (en) | 2008-10-30 | 2020-05-06 | Gruenenthal Gmbh | Powerful new dosage forms of tapentadol |
| NZ596668A (en) | 2009-07-22 | 2013-09-27 | Gruenenthal Chemie | Oxidation-stabilized tamper-resistant dosage form |
| JP5667183B2 (en) | 2009-07-22 | 2015-02-12 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Controlled release dosage form with heat melt extrusion |
| EP2531176B1 (en) * | 2010-02-03 | 2016-09-07 | Grünenthal GmbH | Preparation of a powdery pharmaceutical composition by means of an extruder |
| JP5905872B2 (en) * | 2010-04-07 | 2016-04-20 | ルピン・リミテッド | Controlled release pharmaceutical composition of tapentadol |
| US20130116333A1 (en) * | 2010-05-05 | 2013-05-09 | Ratiopharm Gmbh | Solid tapentadol in non-crystalline form |
| US8846765B2 (en) | 2010-06-15 | 2014-09-30 | Gruenenthal Gmbh | Pharmaceutical combination |
| PT2588093T (en) | 2010-06-30 | 2016-09-21 | Gruenenthal Gmbh | Tapentadol for use in the treatment of irritable bowel syndrome |
| MX341072B (en) | 2010-07-23 | 2016-08-05 | Grünenthal Gmbh * | Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propy l)-phenol. |
| MX2013002293A (en) | 2010-09-02 | 2013-05-09 | Gruenenthal Gmbh | Tamper resistant dosage form comprising an anionic polymer. |
| ES2486791T3 (en) | 2010-09-02 | 2014-08-19 | Grünenthal GmbH | Tamper resistant dosage form comprising an inorganic salt |
| DK2680833T3 (en) | 2011-03-04 | 2016-05-23 | Gruenenthal Gmbh | PARENTERAL SUBMISSION OF TAPENTADOL |
| CN103501773A (en) | 2011-03-04 | 2014-01-08 | 格吕伦塔尔有限公司 | Aqueous pharmaceutical formulation of tapentadol for oral administration |
| LT2694049T (en) | 2011-04-05 | 2018-12-27 | GrĆ¼nenthal GmbH | Tapentadol for preventing chronification of pain |
| JP6040219B2 (en) | 2011-04-05 | 2016-12-07 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Tapentadol for the treatment of pain associated with trigeminal neuropathic pain |
| SI2701693T1 (en) | 2011-04-29 | 2017-11-30 | Gruenenthal Gmbh | Tapentadol for preventing and treating depression and anxiety |
| NO2680834T3 (en) | 2011-05-03 | 2018-03-17 | ||
| WO2013017233A1 (en) | 2011-07-29 | 2013-02-07 | Grünenthal GmbH | Intrathecal or epidural administration of 3-[(1s,2s)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol |
| EA201400172A1 (en) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | SUSTAINABLE TO DESTRUCTION TABLET THAT PROVIDES IMMEDIATE RELEASE OF MEDICINES |
| PE20141650A1 (en) | 2011-07-29 | 2014-11-22 | Gruenenthal Chemie | ALTERATION PROOF TABLET PROVIDING IMMEDIATE RELEASE OF THE DRUG |
| EP2606879A1 (en) | 2011-12-21 | 2013-06-26 | Hexal AG | Multiple unit pellet tablet formulation comprising an opioid |
| WO2013127831A1 (en) | 2012-02-28 | 2013-09-06 | Grünenthal GmbH | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
| ES2692944T3 (en) | 2012-04-18 | 2018-12-05 | Grünenthal GmbH | Pharmaceutical dosage form resistant to handling and resistant to rapid discharge of the dose |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| BR112015026549A2 (en) | 2013-05-29 | 2017-07-25 | Gruenenthal Gmbh | tamper-proof dosage form containing one or more particles |
| US9737490B2 (en) | 2013-05-29 | 2017-08-22 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
| EP2808319A1 (en) | 2013-05-31 | 2014-12-03 | Arevipharma GmbH | 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex |
| AU2014289187B2 (en) | 2013-07-12 | 2019-07-11 | Grunenthal Gmbh | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
| EP2845625A1 (en) | 2013-09-04 | 2015-03-11 | Grünenthal GmbH | Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome |
| WO2015071248A1 (en) | 2013-11-15 | 2015-05-21 | Synthon B.V. | Abuse-proofed extended release pharmaceutical composition comprising tapentadol |
| AU2014356581C1 (en) | 2013-11-26 | 2020-05-28 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
| EP2942054A1 (en) * | 2014-05-09 | 2015-11-11 | G.L. Pharma GmbH | Slow-release pharmaceutical formulation |
| MX2016014738A (en) | 2014-05-12 | 2017-03-06 | Gruenenthal Gmbh | Tamper resistant immediate release capsule formulation comprising tapentadol. |
| CN106456550A (en) | 2014-05-26 | 2017-02-22 | 格吕伦塔尔有限公司 | Multiparticles safeguarded against ethanolic dose-dumping |
| ES2710299T3 (en) | 2015-03-27 | 2019-04-24 | Gruenenthal Gmbh | Stable formulation for parenteral administration of tapentadol |
| BR112017021475A2 (en) | 2015-04-24 | 2018-07-10 | Gruenenthal Gmbh | tamper-resistant dosage form with immediate release and resistance to solvent extraction |
| CA2998259A1 (en) | 2015-09-10 | 2017-03-16 | Grunenthal Gmbh | Protecting oral overdose with abuse deterrent immediate release formulations |
| EP3231420A1 (en) | 2016-02-29 | 2017-10-18 | G.L. Pharma GmbH | Abuse-deterrent pharmaceutical compositions |
| ES3027562T3 (en) | 2016-09-23 | 2025-06-16 | Gruenenthal Gmbh | Stable formulation for parenteral administration of tapentadol |
| WO2018153947A1 (en) | 2017-02-23 | 2018-08-30 | Grünenthal GmbH | Tapentadol as local anesthetic |
| US20180369151A1 (en) * | 2017-05-29 | 2018-12-27 | Grünenthal GmbH | Multiparticulate oral dosage form providing prolonged release of tapentadol |
| EP3875080A1 (en) | 2020-03-02 | 2021-09-08 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| AU2020100441B4 (en) * | 2020-03-02 | 2020-06-18 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| BR112022017700A2 (en) | 2020-03-02 | 2023-01-17 | Gruenenthal Gmbh | DOSAGE FORM PROVIDING EXTENDED RELEASE OF TAPENTADOL PHOSPHORIC ACID SALT |
| AU2020100442B4 (en) * | 2020-03-02 | 2020-06-18 | Grünenthal GmbH | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| HUE064779T2 (en) * | 2020-03-02 | 2024-04-28 | Gruenenthal Gmbh | Dosage form providing prolonged release of tapentadol phosphoric acid salt |
| ES3010208T3 (en) * | 2020-03-16 | 2025-04-01 | Gruenenthal Gmbh | Scored tablet comprising tapentadol |
| DE202020104285U1 (en) | 2020-07-24 | 2020-12-18 | Grünenthal GmbH | Ethyl cellulose-coated particles containing a salt of tapentadol and phosphoric acid |
| HUE059465T2 (en) | 2020-11-10 | 2022-11-28 | Gruenenthal Gmbh | Prolonged release dosage form of tapentadol l-(+)- tartaric acid salt |
| DE202020005470U1 (en) | 2020-11-10 | 2022-01-25 | Grünenthal GmbH | Extended-release dosage forms of a salt of tapentadol with L-(+)-tartaric acid |
| WO2022101247A1 (en) | 2020-11-10 | 2022-05-19 | Grünenthal GmbH | Sustained release dosage forms of a salt of tapentadol with l-(+)-tartaric acid |
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-
2002
- 2002-10-18 PE PE2002001030A patent/PE20030527A1/en active IP Right Grant
- 2002-10-22 DK DK02781278T patent/DK1439829T3/en active
- 2002-10-22 EP EP02781278A patent/EP1439829B1/en not_active Expired - Lifetime
- 2002-10-22 ES ES02781278T patent/ES2248622T3/en not_active Expired - Lifetime
- 2002-10-22 MX MXPA04003742A patent/MXPA04003742A/en active IP Right Grant
- 2002-10-22 KR KR1020047006113A patent/KR100958045B1/en not_active Expired - Lifetime
- 2002-10-22 WO PCT/EP2002/011809 patent/WO2003035053A1/en not_active Ceased
- 2002-10-22 HU HU0402104A patent/HU230161B1/en unknown
- 2002-10-22 PT PT02781278T patent/PT1439829E/en unknown
- 2002-10-22 SI SI200230224T patent/SI1439829T1/en unknown
- 2002-10-22 JP JP2003537620A patent/JP4758064B2/en not_active Expired - Lifetime
- 2002-10-22 WO PCT/EP2002/011806 patent/WO2003035054A1/en not_active Ceased
- 2002-10-22 AT AT02781278T patent/ATE303802T1/en active
- 2002-10-22 AU AU2002349001A patent/AU2002349001C1/en active Active
- 2002-10-22 BR BRPI0213653A patent/BRPI0213653B8/en active IP Right Grant
- 2002-10-22 CA CA2464578A patent/CA2464578C/en not_active Expired - Lifetime
- 2002-10-22 DE DE50204198T patent/DE50204198D1/en not_active Expired - Lifetime
- 2002-10-22 NZ NZ532999A patent/NZ532999A/en not_active IP Right Cessation
- 2002-10-22 CN CNB028259769A patent/CN100402021C/en not_active Expired - Lifetime
- 2002-10-22 PL PL369756A patent/PL216535B1/en unknown
- 2002-10-22 IL IL16158702A patent/IL161587A0/en unknown
- 2002-10-23 AR ARP020104010A patent/AR036943A1/en not_active Application Discontinuation
- 2002-10-24 MY MYPI20023979A patent/MY127797A/en unknown
-
2004
- 2004-04-22 IL IL161587A patent/IL161587A/en active IP Right Grant
- 2004-04-22 CO CO04037005A patent/CO5570662A2/en not_active Application Discontinuation
- 2004-04-26 US US10/831,368 patent/US20050058706A1/en not_active Abandoned
- 2004-05-11 NO NO20041924A patent/NO331896B1/en not_active IP Right Cessation
- 2004-05-12 EC EC2004005102A patent/ECSP045102A/en unknown
- 2004-05-20 ZA ZA2004/03928A patent/ZA200403928B/en unknown
-
2010
- 2010-08-05 JP JP2010176084A patent/JP2010280697A/en active Pending
-
2011
- 2011-09-23 US US13/242,800 patent/US20120034304A1/en not_active Abandoned
-
2012
- 2012-05-08 NO NO2012007C patent/NO2012007I2/en unknown
- 2012-08-13 CY CY2012022C patent/CY2012022I1/en unknown
-
2013
- 2013-04-23 US US13/868,635 patent/US20130237608A1/en not_active Abandoned
-
2016
- 2016-02-08 US US15/018,529 patent/US20160151309A1/en not_active Abandoned
- 2016-12-13 US US15/377,628 patent/US20170087103A1/en not_active Abandoned
-
2018
- 2018-04-02 US US15/943,175 patent/US20180221308A1/en not_active Abandoned
-
2019
- 2019-10-14 US US16/600,974 patent/US11007156B2/en not_active Expired - Fee Related
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