AU2002230734A1 - Nested oligonucleotides containing hairpin for nucleic acid amplification - Google Patents

Nested oligonucleotides containing hairpin for nucleic acid amplification

Info

Publication number: AU2002230734A1
Authority: AU; Australia
Prior art keywords: nucleic acid; acid amplification; oligonucleotides containing; containing hairpin; nested oligonucleotides
Prior art date: 2000-12-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002230734A

Other languages

English (en)

Inventor

Shana Barbas-Frederickson

Katherine S. Bowdish

Ying-Shi Lin

Toshiaki Maruyama

John Mcwhirter

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Alexion Pharmaceuticals Inc

Original Assignee

Alexion Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-11

Filing date

2001-12-10

Publication date

2002-06-24

2001-12-10 Application filed by Alexion Pharmaceuticals Inc filed Critical Alexion Pharmaceuticals Inc

2002-06-24 Publication of AU2002230734A1 publication Critical patent/AU2002230734A1/en

Status Abandoned legal-status Critical Current

Links

108091034117 Oligonucleotide Proteins 0.000 title 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
230000003321 amplification Effects 0.000 title 1
238000003199 nucleic acid amplification method Methods 0.000 title 1
108020004707 nucleic acids Proteins 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 title 1
102000039446 nucleic acids Human genes 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Microbiology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

AU2002230734A 2000-12-11 2001-12-10 Nested oligonucleotides containing hairpin for nucleic acid amplification Abandoned AU2002230734A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US25466900P	2000-12-11	2000-12-11
US60/254,669		2000-12-11
US32340001P	2001-09-19	2001-09-19
US60/323,400		2001-09-19
PCT/US2001/047727 WO2002048401A2 (fr)	2000-12-11	2001-12-10	Oligonucleotides emboites contenant une structure en epingle a cheveux pour l'amplification des acides nucleiques

Publications (1)

Publication Number	Publication Date
AU2002230734A1 true AU2002230734A1 (en)	2002-06-24

Family

ID=26944185

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002230734A Abandoned AU2002230734A1 (en)	2000-12-11	2001-12-10	Nested oligonucleotides containing hairpin for nucleic acid amplification

Country Status (5)

Country	Link
US (3)	US6919189B2 (fr)
EP (1)	EP1366191A2 (fr)
AU (1)	AU2002230734A1 (fr)
CA (1)	CA2436693A1 (fr)
WO (1)	WO2002048401A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2450217A1 (fr) *	2001-05-14	2002-11-21	Henry Hongjun Ji	Nouveau procede pour cloner les sequences a domaine variable du repertoire des genes immunologiques
EP1436404B1 (fr) *	2001-09-19	2009-11-11	Alexion Pharmaceuticals, Inc.	Matrices transgeniques et leurs utilisations dans l'amplification d'amorce unique
US20050208627A1 (en) *	2003-09-18	2005-09-22	Bowdish Katherine S	Elicitation of antibodies to self peptides in mice by immunization with dendritic cells
WO2005027846A2 (fr) *	2003-09-18	2005-03-31	Alexion Pharmaceuticals, Inc.	Sollicitation d'anticorps vers des peptides du soi dans des souris par l'immunisation avec des cellules dendritiques
DK1778867T3 (da)	2004-07-01	2010-08-02	Gen Probe Inc	Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve
US7833716B2 (en) *	2006-06-06	2010-11-16	Gen-Probe Incorporated	Tagged oligonucleotides and their use in nucleic acid amplification methods
CN102292457B (zh) *	2008-11-25	2014-04-09	简·探针公司	检测小rna的组合物和方法及其用途
WO2014085687A1 (fr)	2012-11-28	2014-06-05	Abwiz Bio, Inc.	Préparation de matrices spécifiques de gènes à utiliser dans une amplification d'amorce unique
CN106811459B (zh) *	2015-11-27	2019-09-27	清华大学	一种利用短链引物阻遏提高dna克隆及组装效率的方法
ES2996699T3 (en) *	2016-04-12	2025-02-13	Medimmune Llc	Immune repertoire mining
US12043856B2 (en) *	2016-05-24	2024-07-23	The Translational Genomics Research Institute	Molecular tagging methods and sequencing libraries
WO2025185331A1 (fr) *	2024-03-04	2025-09-12	Cytotest Inc.	Procédés de construction d'une banque de polynucléotides présentant des acides nucléiques d'intérêt

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL63907A0 (en)	1980-09-24	1981-12-31	Cetus Corp	Diagnostic method and antibody probe for use therein
US4582788A (en)	1982-01-22	1986-04-15	Cetus Corporation	HLA typing method and cDNA probes used therein
ATE53862T1 (de)	1982-01-22	1990-06-15	Cetus Corp	Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel.
US4683194A (en)	1984-05-29	1987-07-28	Cetus Corporation	Method for detection of polymorphic restriction sites and nucleic acid sequences
US4683202A (en)	1985-03-28	1987-07-28	Cetus Corporation	Process for amplifying nucleic acid sequences
CA1284931C (fr)	1986-03-13	1991-06-18	Henry A. Erlich	Procede de detection de variations specifiques de nucleotides et de polymorphismes genetiques dans les acides nucleiques
CA1338457C (fr)	1986-08-22	1996-07-16	Henry A. Erlich	Enzyme thermostable purifiee
US5130238A (en)	1988-06-24	1992-07-14	Cangene Corporation	Enhanced nucleic acid amplification process
WO1990005144A1 (fr)	1988-11-11	1990-05-17	Medical Research Council	Ligands a domaine unique, recepteurs comprenant lesdits ligands, procedes pour leur production, et emploi desdits ligands et recepteurs
CA2016842A1 (fr)	1989-05-16	1990-11-16	Richard A. Lerner	Methode pour puiser dans le repertoire immunologique
US5595891A (en)	1990-07-19	1997-01-21	Behringwerke Ag	Method for producing a polynucleotide for use in single primer amplification
ES2104160T3 (es)	1992-07-31	1997-10-01	Behringwerke Ag	Metodo para introducir secuencias definidas en el extremo 3' de polinucleotidos.
FR2724934B1 (fr)	1994-09-26	1997-01-24	Bio Merieux	Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
WO1997004131A1 (fr) *	1995-07-21	1997-02-06	Forsyth Dental Infirmary For Children	Amplification d'epingles a cheveux de polynucleotide avec une seule amorce
US5962271A (en)	1996-01-03	1999-10-05	Cloutech Laboratories, Inc.	Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
US6087099A (en) *	1997-09-08	2000-07-11	Myriad Genetics, Inc.	Method for sequencing both strands of a double stranded DNA in a single sequencing reaction
US6277607B1 (en) *	1999-05-24	2001-08-21	Sanjay Tyagi	High specificity primers, amplification methods and kits
CN102586228A (zh)	1999-09-13	2012-07-18	纽亘技术公司	用于多核苷酸序列线性等温扩增的方法及组合物
US6582938B1 (en) *	2001-05-11	2003-06-24	Affymetrix, Inc.	Amplification of nucleic acids
EP1436404B1 (fr) *	2001-09-19	2009-11-11	Alexion Pharmaceuticals, Inc.	Matrices transgeniques et leurs utilisations dans l'amplification d'amorce unique

2001
- 2001-12-10 EP EP01990978A patent/EP1366191A2/fr not_active Withdrawn
- 2001-12-10 US US10/014,012 patent/US6919189B2/en not_active Expired - Lifetime
- 2001-12-10 AU AU2002230734A patent/AU2002230734A1/en not_active Abandoned
- 2001-12-10 WO PCT/US2001/047727 patent/WO2002048401A2/fr not_active Ceased
- 2001-12-10 CA CA002436693A patent/CA2436693A1/fr not_active Abandoned
2003
- 2003-07-28 US US10/628,109 patent/US20040101886A1/en not_active Abandoned
2009
- 2009-02-18 US US12/378,811 patent/USRE41365E1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2002048401A3 (fr)	2003-09-12
WO2002048401A2 (fr)	2002-06-20
US20040101886A1 (en)	2004-05-27
CA2436693A1 (fr)	2002-06-20
USRE41365E1 (en)	2010-06-01
EP1366191A2 (fr)	2003-12-03
US20050079489A1 (en)	2005-04-14
US6919189B2 (en)	2005-07-19

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AU2002245184A1 (en)	2002-07-08	Nucleic acid amplification
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AU2013202A (en)	2002-06-11	Nucleic acid amplification methods
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AU2002225888A1 (en)	2002-06-18	Double transposition methods for manipulating nucleic acids
AU2002230734A1 (en)	2002-06-24	Nested oligonucleotides containing hairpin for nucleic acid amplification
AU2003220249A1 (en)	2003-09-29	Improved nucleic acid amplification
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AUPR223500A0 (en)	2001-01-25	Nucleic acid sequence