[go: up one dir, main page]

AU2001271669A1 - Multipartite high-affinity nucleic acid probes - Google Patents

Multipartite high-affinity nucleic acid probes

Info

Publication number
AU2001271669A1
AU2001271669A1 AU2001271669A AU7166901A AU2001271669A1 AU 2001271669 A1 AU2001271669 A1 AU 2001271669A1 AU 2001271669 A AU2001271669 A AU 2001271669A AU 7166901 A AU7166901 A AU 7166901A AU 2001271669 A1 AU2001271669 A1 AU 2001271669A1
Authority
AU
Australia
Prior art keywords
multipartite
nucleic acid
acid probes
affinity nucleic
affinity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001271669A
Inventor
Caifu Chen
Michael Egholm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems Inc
Original Assignee
PE Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PE Corp filed Critical PE Corp
Publication of AU2001271669A1 publication Critical patent/AU2001271669A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001271669A 2000-06-30 2001-06-29 Multipartite high-affinity nucleic acid probes Abandoned AU2001271669A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/610,155 US6451588B1 (en) 2000-06-30 2000-06-30 Multipartite high-affinity nucleic acid probes
US09/610,155 2000-06-30
PCT/US2001/020815 WO2002002817A2 (en) 2000-06-30 2001-06-29 Multipartite high-affinity nucleic acid probes

Publications (1)

Publication Number Publication Date
AU2001271669A1 true AU2001271669A1 (en) 2002-01-14

Family

ID=24443889

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001271669A Abandoned AU2001271669A1 (en) 2000-06-30 2001-06-29 Multipartite high-affinity nucleic acid probes

Country Status (3)

Country Link
US (2) US6451588B1 (en)
AU (1) AU2001271669A1 (en)
WO (1) WO2002002817A2 (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030165888A1 (en) 2001-07-18 2003-09-04 Brown Bob D. Oligonucleotide probes and primers comprising universal bases for diagnostic purposes
US6518017B1 (en) * 1997-10-02 2003-02-11 Oasis Biosciences Incorporated Combinatorial antisense library
DK1171634T3 (en) * 1999-04-08 2006-03-20 Gen Probe Inc Amplification and sequencing primer pairs and their use
US20030082549A1 (en) * 2000-08-30 2003-05-01 Xiangjun Liu Method for determining alleles
EP1356104A2 (en) * 2000-10-06 2003-10-29 Nugen Technologies, Inc. Methods and probes for detection and/or quantification of nucleic acid sequences
DE10056802B4 (en) * 2000-11-14 2005-06-16 Epigenomics Ag Method for the detection of methylation conditions for toxicological diagnostics
US9261460B2 (en) 2002-03-12 2016-02-16 Enzo Life Sciences, Inc. Real-time nucleic acid detection processes and compositions
US20040161741A1 (en) * 2001-06-30 2004-08-19 Elazar Rabani Novel compositions and processes for analyte detection, quantification and amplification
US9777312B2 (en) * 2001-06-30 2017-10-03 Enzo Life Sciences, Inc. Dual polarity analysis of nucleic acids
US9353405B2 (en) 2002-03-12 2016-05-31 Enzo Life Sciences, Inc. Optimized real time nucleic acid detection processes
DE60330182D1 (en) * 2002-09-08 2009-12-31 Applera Corp Solid phase bound PNA dimers and their synthesis
WO2004069850A2 (en) * 2003-02-04 2004-08-19 Borer Philip N Switchable nucleic acids for diagnostics, screening and molecular electronics
US8003374B2 (en) 2003-03-25 2011-08-23 The Regents Of The University Of California Reagentless, reusable, bioelectronic detectors
US20040191801A1 (en) * 2003-03-25 2004-09-30 Heeger Alan J. Reagentless, reusable bioelectronic detectors and their use as authentication devices
EP1692486B1 (en) * 2003-12-12 2015-10-28 Saint Louis University Biosensors for detecting macromolecules and other analytes
US8034554B2 (en) * 2004-07-01 2011-10-11 Gen-Probe Incorporated Methods and compositions to detect nucleic acids in a biological sample
US7521546B2 (en) * 2004-08-03 2009-04-21 Syracuse University Branched and multi-chain nucleic acid switches for sensing and screening
US20080311571A1 (en) * 2004-11-19 2008-12-18 Wakunaga Pharmaceutical Co., Ltd. Nucleic Acid Fragments for Detecting Nucleic Acid and Method for Detecting Nucleic Acid
JP2006166911A (en) * 2004-11-19 2006-06-29 Wakunaga Pharmaceut Co Ltd Nucleic acid fragment for detecting nucleic acid and method of detecting nucleic acid
US7795009B2 (en) * 2005-06-15 2010-09-14 Saint Louis University Three-component biosensors for detecting macromolecules and other analytes
US8956857B2 (en) 2005-06-06 2015-02-17 Mediomics, Llc Three-component biosensors for detecting macromolecules and other analytes
EP1907410B1 (en) * 2005-06-10 2012-07-04 Saint Louis University Methods for the selection of aptamers
US20060281100A1 (en) * 2005-06-14 2006-12-14 Shen Gene G Thiotriphosphate nucleotide dye terminators
US7811809B2 (en) * 2005-06-15 2010-10-12 Saint Louis University Molecular biosensors for use in competition assays
EP1910575B1 (en) * 2005-07-01 2014-12-10 Dako Denmark A/S Immunohistochemistry detection method
US7803542B2 (en) * 2005-11-29 2010-09-28 The Regents Of The University Of California Signal-on architecture for electronic, oligonucleotide-based detectors
WO2007101075A2 (en) * 2006-02-22 2007-09-07 Applera Corporation Double-ligation method for haplotype and large-scale polymorphism detection
WO2007146811A2 (en) * 2006-06-09 2007-12-21 University Of Miami Assessment of cellular composition and fractional viability and uses thereof
US20120258880A1 (en) * 2010-11-22 2012-10-11 The University Of Chicago Methods and/or Use of Oligonucleotide Conjugates for Assays and Flow Cytometry Detections
AU2009246363B2 (en) * 2008-05-13 2013-10-24 Gen-Probe Incorporated Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences
WO2010059126A1 (en) * 2008-11-20 2010-05-27 Agency For Science, Technology And Research Sensor for detection of nucleic acid
CN102317779A (en) 2008-11-21 2012-01-11 圣路易大学 Biosensor for detecting multiple epitopes on a target
JP2012509675A (en) * 2008-11-25 2012-04-26 ジェン−プロウブ インコーポレイテッド Compositions and methods for detecting small RNAs and uses thereof
US8409802B2 (en) * 2009-08-14 2013-04-02 Roche Molecular Systems, Inc. Format of probes to detect nucleic acid differences
US9040287B2 (en) 2010-02-12 2015-05-26 Mediomics, Llc Molecular biosensors capable of signal amplification
WO2012149154A1 (en) * 2011-04-26 2012-11-01 Swift Biosciences, Inc. Polynucleotide primers and probes
US20140038182A1 (en) 2012-07-17 2014-02-06 Dna Logix, Inc. Cooperative primers, probes, and applications thereof
EP2875132A4 (en) * 2012-07-17 2016-02-24 Dna Logix Inc Cooperative primers, probes, and applications thereof
WO2014145620A2 (en) * 2013-03-15 2014-09-18 The Broad Institute, Inc. Novel hybridization probes and uses thereof
US20160161472A1 (en) 2013-07-30 2016-06-09 President And Fellows Of Harvard College Quantitative dna-based imaging and super-resolution imaging
WO2016040830A1 (en) 2014-09-12 2016-03-17 Mediomics, Llc Molecular biosensors with a modular design
US20170349940A1 (en) * 2014-09-26 2017-12-07 Two Pore Guys, Inc. Targeted Sequence Detection by Nanopore Sensing of Synthetic Probes
US10036066B2 (en) 2015-03-17 2018-07-31 Dako Denmark A/S In situ hybridization detection method
CA2991045A1 (en) 2015-06-29 2017-01-05 Caris Science, Inc. Therapeutic oligonucleotides binding c1q
CN107924473B (en) * 2015-08-07 2021-11-23 哈佛学院院长及董事 Super-resolution imaging of protein-protein interactions
US20170081713A1 (en) * 2015-09-03 2017-03-23 Nanostring Technologies, Inc. Multivalent probes having single nucleotide resolution
US11486873B2 (en) 2016-03-31 2022-11-01 Ontera Inc. Multipore determination of fractional abundance of polynucleotide sequences in a sample
WO2019200326A1 (en) 2018-04-13 2019-10-17 Rarecyte, Inc. Kits for labeling of biomarkers and methods of using the same
WO2020068983A1 (en) * 2018-09-25 2020-04-02 Co-Diagnostics, Inc. Allele-specific design of cooperative primers for improved nucleic acid variant genotyping

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3042626B2 (en) * 1988-05-24 2000-05-15 ゲゼルシャフト フュア バイオテクノロギッシェ フォーシュング エムベーハー（ゲーベーエフ） Determination of DNA base sequence using oligonucleotide bank
CA2036337C (en) * 1990-02-15 2003-04-15 Francois Clemence Derivatives of 20,21-dinoreburnamenin, their preparation process and the new intermediates thus obtained, their application as drugs and the compositions containing such
US6140490A (en) * 1996-02-01 2000-10-31 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands of complement system proteins
US5695926A (en) * 1990-06-11 1997-12-09 Bio Merieux Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support
US5424413A (en) * 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
US5663062A (en) 1992-04-03 1997-09-02 Stratagene Oligonucleotide libraries useful for producing primers
DE4344742A1 (en) 1993-06-09 1994-12-15 Boehringer Mannheim Gmbh Method for the immobilization of nucleic acids
US5861242A (en) * 1993-06-25 1999-01-19 Affymetrix, Inc. Array of nucleic acid probes on biological chips for diagnosis of HIV and methods of using the same
US5527675A (en) * 1993-08-20 1996-06-18 Millipore Corporation Method for degradation and sequencing of polymers which sequentially eliminate terminal residues
US5854410A (en) 1994-03-31 1998-12-29 Genta Incorporated Oligonucleoside cleavage compounds and therapies
US5821060A (en) 1996-08-02 1998-10-13 Atom Sciences, Inc. DNA sequencing, mapping, and diagnostic processes using hybridization chips and unlabeled DNA
US5935791A (en) 1997-09-23 1999-08-10 Becton, Dickinson And Company Detection of nucleic acids by fluorescence quenching
DE69841849D1 (en) * 1997-10-27 2010-09-30 Boston Probes Inc PROCEDURES, TEST PHRASES AND COMPOSITIONS RELATING TO "PNA MOLECULAR BEACONS"
DE1051515T1 (en) 1998-01-27 2001-04-19 Cytocell Ltd., Banbury MODIFIED NUCLEIC ACID PROBES AND THEIR USE
WO1999049293A2 (en) * 1998-03-24 1999-09-30 Boston Probes, Inc. Methods, kits and compositions pertaining to detection complexes
US6287772B1 (en) * 1998-04-29 2001-09-11 Boston Probes, Inc. Methods, kits and compositions for detecting and quantitating target sequences
US6255476B1 (en) * 1999-02-22 2001-07-03 Pe Corporation (Ny) Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports

Also Published As

Publication number Publication date
US20030064402A1 (en) 2003-04-03
WO2002002817A2 (en) 2002-01-10
US6451588B1 (en) 2002-09-17
WO2002002817A3 (en) 2003-03-27

Similar Documents

Publication Publication Date Title
AU2001271669A1 (en) Multipartite high-affinity nucleic acid probes
AU2002245184A1 (en) Nucleic acid amplification
AU2013202A (en) Nucleic acid amplification methods
AU2001295732A1 (en) Concatenated nucleic acid sequences
AU2001273453A1 (en) Nucleic acid hairpin probes and uses thereof
AU2002257076A1 (en) Nucleic acid shuffling
AU2001268513A1 (en) Nucleic acid accessible hybridization sites
AU2001278783A1 (en) Method of amplifying nucleic acid
AU2002314693A1 (en) Nucleic acid amplification method
IL149491A0 (en) Nucleic acid-containing complex
AU2001270797A1 (en) Nucleic acid binding polypeptides
PL358811A1 (en) High order nucleic acid based structures
AU2001280167A1 (en) Novel propenohydroxamic acid derivatives
AU2001261476A1 (en) Nucleic acid sequences for novel gpcrs
AU2001242625A1 (en) Gene sequence
AU2002213164A1 (en) Detection of dna damage
AU2001240103A1 (en) Reproduction-specific genes
AU2002366435A1 (en) Nucleic acid amplification
AU2001292922A1 (en) Nucleic acid detection
AU2001252390A1 (en) Nucleic acid immunization
AU2001291975A1 (en) Use of a nucleic acid/pei complex
AU5049001A (en) Dna analysis
AU6382000A (en) Genome analysis
AU2001279929A1 (en) Means for targeting nucleic acid repeat regions
AUPR223500A0 (en) Nucleic acid sequence