AU2001229679A1 - Reduced form of coenzyme q in high bioavailability stable dosage forms and related applications - Google Patents
Reduced form of coenzyme q in high bioavailability stable dosage forms and related applicationsInfo
- Publication number
- AU2001229679A1 AU2001229679A1 AU2001229679A AU2967901A AU2001229679A1 AU 2001229679 A1 AU2001229679 A1 AU 2001229679A1 AU 2001229679 A AU2001229679 A AU 2001229679A AU 2967901 A AU2967901 A AU 2967901A AU 2001229679 A1 AU2001229679 A1 AU 2001229679A1
- Authority
- AU
- Australia
- Prior art keywords
- coenzyme
- dosage forms
- related applications
- reduced form
- high bioavailability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000005515 coenzyme Substances 0.000 title 1
- 239000002552 dosage form Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09488332 | 2000-01-20 | ||
| US09/488,332 US6740338B1 (en) | 2000-01-20 | 2000-01-20 | Reduced form of Cenzyme Q in high bioavailability stable oral dosage form |
| US09637559 | 2000-08-11 | ||
| US09/637,559 US8753675B1 (en) | 2000-01-20 | 2000-08-11 | Reduced form of Coenzyme Q in high bioavailability stable dosage forms and related applications |
| PCT/US2001/001997 WO2001052822A1 (en) | 2000-01-20 | 2001-01-18 | Reduced form of coenzyme q in high bioavailability stable dosage forms and related applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001229679A1 true AU2001229679A1 (en) | 2001-07-31 |
Family
ID=27049313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001229679A Abandoned AU2001229679A1 (en) | 2000-01-20 | 2001-01-18 | Reduced form of coenzyme q in high bioavailability stable dosage forms and related applications |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8753675B1 (en) |
| EP (1) | EP1251834B1 (en) |
| AU (1) | AU2001229679A1 (en) |
| CA (1) | CA2397447C (en) |
| WO (1) | WO2001052822A1 (en) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20010129A1 (en) | 2001-01-25 | 2002-07-25 | Pharmacia & Upjohn Spa | ESSENTIAL FATTY ACIDS IN THE THERAPY OF HEART INSUFFICIENCY AND HEART FAILURE |
| JP3742602B2 (en) * | 2001-05-09 | 2006-02-08 | 株式会社カネカ | Stable solution of reduced coenzyme Q |
| CA2443191A1 (en) | 2001-05-10 | 2002-11-21 | Kaneka Corporation | Compositions for transmucosal administration containing coenzyme q as the active ingredient |
| JP2003026567A (en) * | 2001-05-10 | 2003-01-29 | Kanegafuchi Chem Ind Co Ltd | Composition for administration to mucosa and containing coenzyme q as active ingredient |
| DE10133305B4 (en) | 2001-07-12 | 2004-06-03 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Ubiquinone concentrate |
| TWI310029B (en) * | 2001-07-13 | 2009-05-21 | Kaneka Corp | |
| TWI235146B (en) | 2001-07-16 | 2005-07-01 | Kaneka Corp | Method of stabilizing reduced coenzyme q10 and method of acidic crystallization |
| US20030044474A1 (en) * | 2001-08-03 | 2003-03-06 | Shaklee Corporation | High molecular weight, lipophilic, orally ingestible bioactive agents in formulations having improved bioavailability |
| JP3822479B2 (en) | 2001-10-10 | 2006-09-20 | 株式会社カネカ | Stabilized composition of reduced coenzyme Q aqueous solution |
| TWI329510B (en) * | 2001-10-10 | 2010-09-01 | Kaneka Corp | Method of stabilizing reduced coenzyme q10 |
| TW200302056A (en) * | 2002-01-18 | 2003-08-01 | Kaneka Corp | Method for stabilizing reduced coenzyme Q10 and composition therefor |
| TW200304372A (en) * | 2002-03-20 | 2003-10-01 | Kanegafuchi Chemical Ind | Compositions for diabetes |
| TWI322008B (en) * | 2003-01-31 | 2010-03-21 | Kaneka Corp | Fatigue improving agent including reduced coenzyme q10 |
| AU2004277951B2 (en) | 2003-09-29 | 2010-11-11 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| CN1909895A (en) * | 2004-01-08 | 2007-02-07 | 株式会社钟化 | Antiaging composition |
| US7708990B2 (en) | 2004-03-23 | 2010-05-04 | Kaneka Corporation | Coenzyme Q compositions persisting in blood |
| EP1728506A1 (en) * | 2004-03-23 | 2006-12-06 | Kaneka Corporation | Coenzyme q composition with long-term persistence in blood |
| WO2005097091A1 (en) * | 2004-04-09 | 2005-10-20 | Kaneka Corporation | Composition comprising reduced-form coenzyme q10 and carotenoid compound |
| TW200603786A (en) * | 2004-05-11 | 2006-02-01 | Kaneka Corp | Anti-fatigue composition |
| JP2006070016A (en) * | 2004-08-02 | 2006-03-16 | Kaneka Corp | Whitening composition containing reduced coenzyme q |
| RU2007128342A (en) * | 2004-12-24 | 2009-01-27 | Канека Корпорейшн (Jp) | A SOLID PRODUCT CONTAINING RESTORED CO-ENZYME Q10 AND METHOD OF PRODUCING IT |
| US8067217B2 (en) | 2004-12-28 | 2011-11-29 | Kaneka Corporation | Method for preserving reduced coenzyme Q10 |
| US20080254016A1 (en) * | 2005-03-29 | 2008-10-16 | Kaneka Corporation | Composition For Increasing Anti-Oxidation Activity In Blood |
| CN1853728A (en) * | 2005-04-19 | 2006-11-01 | 上海天博生物科技有限公司 | Method prescription and use for improving medicine or nutrient oral absorption |
| EP2564843B1 (en) | 2005-06-01 | 2018-12-26 | Bioelectron Technology Corporation | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US20090226408A1 (en) * | 2005-06-24 | 2009-09-10 | Kaneka Corporation | Anti-fatigue composition |
| DE102005032352A1 (en) * | 2005-07-08 | 2007-01-11 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Solubilizer for an active ingredient concentrate in the food industry comprises a St. John's wort extract, a roseda extract or a tarragon extract, a polysorbate emulsifier and water |
| LT1933821T (en) | 2005-09-15 | 2020-11-10 | Ptc Therapeutics, Inc. | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| WO2007034852A1 (en) * | 2005-09-22 | 2007-03-29 | Kaneka Corporation | Composition for life extension and method of extending the life |
| JP5015548B2 (en) * | 2005-10-31 | 2012-08-29 | 株式会社カネカ | Method for stabilizing reduced coenzyme Q10 |
| US8506956B2 (en) | 2005-10-31 | 2013-08-13 | Kaneka Corporation | Method for stabilizing reduced coenzyme Q10 |
| EP1986636B1 (en) | 2006-02-22 | 2013-04-24 | Edison Pharmaceuticals, Inc. | Phenol and 1,4-benzoquinone derivatives for use in the treatment of mitochondrial diseases |
| TW200808344A (en) | 2006-04-28 | 2008-02-16 | Kaneka Corp | Stabilization method of reduced coenzyme Q10 |
| AU2007261943B2 (en) | 2006-06-22 | 2012-11-01 | Kaneka Corporation | Reduced coenzyme Q10-containing composition and method for producing the same |
| US8642030B2 (en) * | 2006-08-25 | 2014-02-04 | Epc Europe Gmbh | Compositions containing coenzyme Q-10 and dihydrolipoic acid |
| US8343541B2 (en) | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
| WO2008119605A1 (en) * | 2007-04-02 | 2008-10-09 | Unilever Plc | Toothpaste composition |
| WO2009025277A1 (en) | 2007-08-22 | 2009-02-26 | Kaneka Corporation | Method of producing reduced coenzyme q10 and method of stabilizing the same |
| WO2009044852A1 (en) * | 2007-10-05 | 2009-04-09 | Kaneka Corporation | Method of producing reduced coenzyme q10 |
| CN101307338B (en) | 2008-07-17 | 2012-04-25 | 任雷 | Preparation method of reduced coenzyme Q10 |
| MX363223B (en) | 2008-09-10 | 2019-03-15 | Bioelectron Tech Corp | TREATMENT OF GENERALIZED DISORDERS OF THE DEVELOPMENT WITH THERAPEUTICS WITH REDOX ACTIVITY. |
| CN101514148B (en) * | 2009-03-27 | 2015-05-13 | 玉溪健坤生物药业有限公司 | Method for preparing reduced coenzyme Q10 |
| WO2011045934A1 (en) | 2009-10-16 | 2011-04-21 | 株式会社カネカ | Method for producing reduced coenzyme q10, method for stabilizing same, and composition comprising same |
| US8557236B2 (en) | 2010-02-09 | 2013-10-15 | Vascure Natural LLC | Cardiovascular support supplement and compositions and methods thereof |
| US11400058B2 (en) | 2010-03-12 | 2022-08-02 | Berg Llc | Intravenous formulations of coenzyme Q10 (CoQ10) and methods of use thereof |
| JP5546935B2 (en) * | 2010-04-20 | 2014-07-09 | 株式会社カネカ | Reduced coenzyme Q10-containing composition and method for producing the same |
| IT1400695B1 (en) * | 2010-06-21 | 2013-06-28 | Labomar S R L | PHARMACEUTICAL AND / OR NUTRACEUTICAL COMPOSITIONS CONTAINING ACTIVE INSOLUBLES IN WATER AND PROCEDURE TO OBTAIN THEM. |
| JP5344768B2 (en) * | 2010-08-11 | 2013-11-20 | クラシエフーズ株式会社 | Coenzyme Q10 photodegradation inhibitor and oral composition |
| US9655849B2 (en) | 2011-03-18 | 2017-05-23 | Particle Dynamics International, Llc | Solid particulate compositions comprising coenzyme Q10 |
| EA201490047A1 (en) | 2011-06-17 | 2014-08-29 | Берг Ллк | INHALATION PHARMACEUTICAL COMPOSITIONS |
| US20140107223A1 (en) * | 2012-10-12 | 2014-04-17 | Whitehill Oral Technologies, Inc. | Topical ubiquinol supplement skin care compositions |
| WO2017106803A1 (en) | 2015-12-17 | 2017-06-22 | Bioelectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| ES2685329B1 (en) * | 2017-03-30 | 2019-07-22 | Phidinut S L | Oral composition for deep mouth cleaning |
| ES2645028B2 (en) * | 2017-10-13 | 2018-06-04 | Maria D. GÓMEZ GARRE | Single and stable pharmaceutical preparation containing berberine, in slow-release formulation, a statin and ubiquinol for the treatment of cardiovascular disease and associated risk factors |
| US11471426B2 (en) | 2019-10-16 | 2022-10-18 | American River Nutrition, Llc | Compositions comprising quinone and/or quinol and methods of preparations and use thereof |
| DE102019218240A1 (en) * | 2019-11-26 | 2021-05-27 | Beiersdorf Ag | Active ingredient combinations of ubiquinol and glyceryl stearate citrate and cosmetic or dermatological preparations containing such active ingredient combinations |
| US20240245628A1 (en) * | 2023-01-03 | 2024-07-25 | Bausch + Lomb Ireland Limited | Compositions and methods for health comprising co-enzyme q10 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH655005A5 (en) * | 1983-02-16 | 1986-03-27 | Sigma Tau Ind Farmaceuti | PHARMACEUTICAL COMPOSITION WITH METABOLIC AND ENERGY ACTION USABLE IN CARDIAC AND VASCULAR THERAPY. |
| EP0150688B1 (en) | 1983-12-28 | 1987-04-22 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
| IT1191608B (en) * | 1985-02-01 | 1988-03-23 | Zambon Spa | PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL FORMS THAT CONTAIN IT |
| CA2007983C (en) | 1989-01-18 | 1996-12-10 | Michael S. Brown | Coenzyme q10 with hmg-coa reductase inhibitors |
| US4929437A (en) * | 1989-02-02 | 1990-05-29 | Merck & Co., Inc. | Coenzyme Q10 with HMG-CoA reductase inhibitors |
| US4933165A (en) | 1989-01-18 | 1990-06-12 | Merck & Co., Inc. | Coenzyme Q10 with HMG-CoA reductase inhibitors |
| US5316765A (en) | 1989-09-07 | 1994-05-31 | Karl Folkers Foundation For Biomedical And Clinical Research | Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies |
| US5082650A (en) | 1989-09-07 | 1992-01-21 | Folkers Karl A | Amelioration of reductions of coenzyme Q10 in cardiomyopathy patients receiving lovastatin |
| US5409693A (en) | 1989-10-12 | 1995-04-25 | Perricone; Nicholas V. | Method for treating and preventing sunburn and sunburn damage to the skin |
| US5312819A (en) * | 1990-08-20 | 1994-05-17 | Sandoz Ltd. | Pharmaceutical compositions comprising clozapine and a radical scavenger |
| SE9101642D0 (en) * | 1991-05-30 | 1991-05-30 | Kabi Pharmacia Ab | phospholipids |
| IT1275434B (en) * | 1995-05-19 | 1997-08-07 | Farmila Farma Milano | PHARMACEUTICAL AND / OR DIETARY COMPOSITIONS WITH ANTIOXIDANT ACTIVITY |
| US6056971A (en) | 1996-07-24 | 2000-05-02 | Biosytes Usa, Inc. | Method for enhancing dissolution properties of relatively insoluble dietary supplements and product incorporating same |
| US5895652A (en) * | 1996-07-29 | 1999-04-20 | Longevity Institute International | Method of metabolic adjuvanation and cellular repair |
| JP3889481B2 (en) | 1996-08-16 | 2007-03-07 | 株式会社カネカ | Pharmaceutical composition |
| JP3926888B2 (en) | 1997-05-27 | 2007-06-06 | 株式会社カネカ | Cholesterol lowering agent |
| US6207137B1 (en) * | 1997-06-12 | 2001-03-27 | C.S. Bioscience, Inc. | Dental formulation |
| AU9209898A (en) * | 1997-09-02 | 1999-03-22 | Ricex Company, Inc., The | A method for treating hypercholesterolemia, hyperlipidemia, and atherosclerosis |
| US5908613A (en) * | 1997-09-08 | 1999-06-01 | Bozzacco; Craig | Composition for the treatment and prevention of periodontal disease |
| US6066327A (en) * | 1997-12-17 | 2000-05-23 | Color Access, Inc. | Antioxidant mixture |
| US6045826A (en) | 1999-04-02 | 2000-04-04 | National Research Council Of Canada | Water-soluble compositions of bioactive lipophilic compounds |
| US6805880B1 (en) * | 1999-08-20 | 2004-10-19 | Ferrosan A/S | Pharmaceutical delivery system for vitamin C and vitamin E and use of a combination of vitamin C and E for preventing or treating conditions involving oxidative stress |
| US6998501B1 (en) * | 1999-08-30 | 2006-02-14 | Ocean Nutrition Canada Limited | Nutritional supplement for lowering serum triglyceride and cholesterol levels |
| US6441050B1 (en) * | 2000-08-29 | 2002-08-27 | Raj K. Chopra | Palatable oral coenzyme Q liquid |
| US6300377B1 (en) * | 2001-02-22 | 2001-10-09 | Raj K. Chopra | Coenzyme Q products exhibiting high dissolution qualities |
-
2000
- 2000-08-11 US US09/637,559 patent/US8753675B1/en not_active Expired - Fee Related
-
2001
- 2001-01-18 AU AU2001229679A patent/AU2001229679A1/en not_active Abandoned
- 2001-01-18 WO PCT/US2001/001997 patent/WO2001052822A1/en not_active Ceased
- 2001-01-18 CA CA002397447A patent/CA2397447C/en not_active Expired - Lifetime
- 2001-01-18 EP EP01942547.9A patent/EP1251834B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2397447A1 (en) | 2001-07-26 |
| EP1251834B1 (en) | 2014-05-28 |
| CA2397447C (en) | 2009-08-11 |
| US8753675B1 (en) | 2014-06-17 |
| EP1251834A1 (en) | 2002-10-30 |
| EP1251834A4 (en) | 2008-11-05 |
| WO2001052822A1 (en) | 2001-07-26 |
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