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AU2001219185A1 - 2-acylaminobenzimidazole derivatives for treating glaucoma - Google Patents

2-acylaminobenzimidazole derivatives for treating glaucoma

Info

Publication number
AU2001219185A1
AU2001219185A1 AU2001219185A AU1918501A AU2001219185A1 AU 2001219185 A1 AU2001219185 A1 AU 2001219185A1 AU 2001219185 A AU2001219185 A AU 2001219185A AU 1918501 A AU1918501 A AU 1918501A AU 2001219185 A1 AU2001219185 A1 AU 2001219185A1
Authority
AU
Australia
Prior art keywords
acylaminobenzimidazole
derivatives
treating glaucoma
glaucoma
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001219185A
Inventor
Mark R Hellberg
Abdelmuola Namil
Andrew Rusinko Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Inc
Original Assignee
Alcon Universal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Universal Ltd filed Critical Alcon Universal Ltd
Publication of AU2001219185A1 publication Critical patent/AU2001219185A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001219185A 2000-03-17 2000-11-14 2-acylaminobenzimidazole derivatives for treating glaucoma Abandoned AU2001219185A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19028000P 2000-03-17 2000-03-17
US60190280 2000-03-17
PCT/US2000/031260 WO2001070705A1 (en) 2000-03-17 2000-11-14 2-acylaminobenzimidazole derivatives for treating glaucoma

Publications (1)

Publication Number Publication Date
AU2001219185A1 true AU2001219185A1 (en) 2001-10-03

Family

ID=22700685

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001219185A Abandoned AU2001219185A1 (en) 2000-03-17 2000-11-14 2-acylaminobenzimidazole derivatives for treating glaucoma

Country Status (3)

Country Link
US (1) US6660870B1 (en)
AU (1) AU2001219185A1 (en)
WO (1) WO2001070705A1 (en)

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Publication number Priority date Publication date Assignee Title
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
AU784462B2 (en) * 2000-03-31 2006-04-06 Purdue Research Foundation Phosphoramidate prodrugs
US6683080B2 (en) 2001-02-02 2004-01-27 Pfizer Inc. Treatment of diabetes mellitus
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
ATE511840T1 (en) * 2001-10-09 2011-06-15 Amgen Inc IMIDAZOLE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS
BR0214019A (en) 2001-11-09 2004-10-13 Boehringer Ingelheim Phamaceut Benzimidazoles Useful as Protein Kinase Inhibitors
TW593302B (en) * 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
US7244847B2 (en) 2002-02-06 2007-07-17 Isis Pharmaceuticals, Inc. Benzimidazole compounds
US7138420B2 (en) 2002-08-08 2006-11-21 Boehringer Ingelheim Pharmaceuticals Inc. Substituted benzimidazole compounds
JP2006501245A (en) * 2002-08-30 2006-01-12 アルコン，インコーポレイテッド Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma
AU2003298839A1 (en) 2002-12-03 2004-06-23 Isis Pharmaceuticals, Inc. Benzimidazoles and analogs thereof as antivirals
EP1581209A4 (en) * 2002-12-13 2009-03-11 Alcon Inc Novel benzopyran analogs and their use for the treatment of glaucoma
US7476687B2 (en) * 2003-11-26 2009-01-13 Alcon, Inc. Substituted furo[2,3-g]indazoles for the treatment of glaucoma
WO2005058911A2 (en) * 2003-12-15 2005-06-30 Alcon, Inc. Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
US7129257B1 (en) * 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US7425572B2 (en) * 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
WO2012071476A2 (en) 2010-11-24 2012-05-31 David Haffner Drug eluting ocular implant
JP5937004B2 (en) 2009-05-18 2016-06-22 ドーズ メディカル コーポレーションＤｏｓｅ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ Drug-eluting intraocular implant
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
CN103168032A (en) 2010-08-05 2013-06-19 安美基公司 Benzimidazole and azabenzimidazole compounds inhibiting anaplastic lymphoma kinase
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
AP2014007595A0 (en) * 2011-09-30 2014-04-30 Kineta Inc Anti-viral compounds
EP3148491B1 (en) 2014-05-29 2020-07-01 Glaukos Corporation Implants with controlled drug delivery features and manufacturing method for said implants
US11925578B2 (en) 2015-09-02 2024-03-12 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
JP7003110B2 (en) 2016-04-20 2022-01-20 ドーズ メディカル コーポレーション Bioabsorbable eye drug delivery device

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534580A1 (en) 1982-10-13 1984-04-20 Synthelabo PHENYL-1 PIPERIDINO-2 PROPANOL DERIVATIVES, THEIR PREPARATION, AND MEDICINES THAT CONTAIN THEM
US5151444B1 (en) 1987-09-18 1999-07-06 R Tech Ueno Ltd Ocular hypotensive agents
US5296504A (en) 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
ATE420857T1 (en) 1988-09-06 2009-01-15 Pfizer Health Ab PROSTAGLANDIN DERIVATIVES FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION
AU1928892A (en) 1991-06-21 1993-01-25 Smithkline Beecham Plc Tryptamine analogues, their synthesis and their use as 5-ht1-like or 5-ht2 receptor agonists
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5922773A (en) 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment
US5510383A (en) 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
TW270114B (en) 1993-10-22 1996-02-11 Hoffmann La Roche
US5874477A (en) 1994-08-12 1999-02-23 The University Of Hawaii Method of treatment for malaria utilizing serotonin receptor ligands
US5902815A (en) 1996-09-03 1999-05-11 Washington University Use of 5HT-2A serotonin agonists to prevent adverse effects of NMDA receptor hypofunction
GB9700899D0 (en) 1997-01-17 1997-03-05 Smithkline Beecham Plc Novel treatment
ATE310566T1 (en) 1998-09-18 2005-12-15 Alcon Mfg Ltd 5HT2 AGONITS FOR THE TREATMENT OF GLAUCOMA

Also Published As

Publication number Publication date
WO2001070705A1 (en) 2001-09-27
US6660870B1 (en) 2003-12-09

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