AU2001278694A1 - Avermectin derivatives - Google Patents

Avermectin derivatives

Info

Publication number: AU2001278694A1
Authority: AU; Australia
Prior art keywords: avermectin derivatives; avermectin; derivatives
Prior art date: 2000-08-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2001278694A

Inventor

Kenichiro Nagai

Satoshi Omura

Toshiaki Sunazuka

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kitasato Institute

Original Assignee

Kitasato Institute

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-09

Filing date

2001-08-08

Publication date

2002-02-18

2001-08-08 Application filed by Kitasato Institute filed Critical Kitasato Institute

2002-02-18 Publication of AU2001278694A1 publication Critical patent/AU2001278694A1/en

Status Abandoned legal-status Critical Current

Links

RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AU2001278694A 2000-08-09 2001-08-08 Avermectin derivatives Abandoned AU2001278694A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2000-240988		2000-08-09
JP2000240988		2000-08-09
PCT/JP2001/006803 WO2002012248A1 (en)	2000-08-09	2001-08-08	Avermectin derivatives

Publications (1)

Publication Number	Publication Date
AU2001278694A1 true AU2001278694A1 (en)	2002-02-18

Family

ID=18732258

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2001278694A Abandoned AU2001278694A1 (en)	2000-08-09	2001-08-08	Avermectin derivatives

Country Status (5)

Country	Link
US (2)	US20040087519A1 (en)
JP (2)	JPWO2002012248A1 (en)
AU (1)	AU2001278694A1 (en)
CA (1)	CA2418975C (en)
WO (1)	WO2002012248A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EG23124A (en) *	2001-02-27	2004-04-28	Syngenta Participations Ag	Avermectins substituted in the 4-position having pesticidal properties
CR6574A (en) *	2001-02-27	2004-10-28	Syngenta Participations Ag	SALTS OF SUBSTITUTED FINDINGS IN POSITION 4 WITH PESTICIATED PROPERTIES
AR036486A1 (en) *	2001-08-28	2004-09-15	Syngenta Participations Ag	DERIVATIVES 4 "-DESOXI-4" - (S) -AMINO AVERMECTINA, PESTICIDE COMPOSITION, PROCEDURE FOR THE PREPARATION OF THAT COMPOSITION, METHOD FOR CONTROLLING PESTS, AND USE OF THESE DERIVATIVES TO PREPARE A COMPOSITION
AR040073A1 (en) *	2002-05-07	2005-03-16	Syngenta Participations Ag	4 '' DERIVATIVES - DESOXI-4 '' - (S) -AMIDO AVERMECTINA AND ITS USE AS PESTICIDES
GB0229804D0 (en) *	2002-12-20	2003-01-29	Syngenta Participations Ag	Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position
GB0302308D0 (en) *	2003-01-31	2003-03-05	Syngenta Participations Ag	Avermectin and avermectin monosaccharide derivatives substituted in the 4"- or 4'-position having pesticidal properties
GB0302309D0 (en) *	2003-01-31	2003-03-05	Syngenta Participations Ag	Avermectin monosaccharide derivatives substituted in the 4 -position having pesticidal properties
GB0302310D0 (en) *	2003-01-31	2003-03-05	Syngenta Participations Ag	Avermectin- and avermectin monosaccharide derivatives substituted in the 4"- or 4' - positionhaving pesticidal properties
GB0302547D0 (en) *	2003-02-04	2003-03-12	Syngenta Participations Ag	Avermectins and avermectin monosaccharide substituted in the 4'- and 4" position having pesticidal properties
GB0320176D0 (en) *	2003-08-28	2003-10-01	Syngenta Participations Ag	Avermectins and avermectin monosaccharides substitued in the 4'-and 4"-positionhaving pesticidal properties
US7941389B2 (en) *	2006-02-10	2011-05-10	Numenta, Inc.	Hierarchical temporal memory based system including nodes with input or output variables of disparate properties
DE102007007750A1 (en)	2006-08-17	2008-02-21	Bayer Cropscience Ag	avermectin derivatives
EP2105107A1 (en) *	2008-03-27	2009-09-30	BrainLAB AG	Method for calibrating axial medicinal or medical technical instruments
TWI457347B (en)	2008-12-04	2014-10-21	Merial Ltd	Dimeric avermectin and milbemycin derivatives
WO2011075592A1 (en)	2009-12-17	2011-06-23	Merial Limited	Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
EP2768513B8 (en)	2011-10-18	2020-05-20	Institut national de recherche pour l'agriculture, l'alimentation et l'environnement	Use of avermectin derivative for increasing bioavailability and efficacy of macrocylic lactones
PL2785719T3 (en)	2011-12-02	2018-03-30	Merial, Inc.	Long-acting injectable moxidectin formulations and novel moxidectin crystal forms
CN104231022B (en) *	2013-06-14	2018-10-09	南开大学	A kind of preparation and application of macrolides compound
CN103421065B (en) *	2013-07-03	2016-05-18	大庆志飞生物化工有限公司	One class Novel Abamectin derivative and preparation method thereof
WO2024135828A1 (en)	2022-12-23	2024-06-27	ＭｅｉｊｉＳｅｉｋａファルマ株式会社	Avermectin derivative

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4200581A (en) *	1978-08-04	1980-04-29	Merck & Co., Inc.	Alkyl derivatives of C-076 compounds
US4427663A (en) *	1982-03-16	1984-01-24	Merck & Co., Inc.	4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4833168A (en)	1986-10-03	1989-05-23	Merck & Co., Inc.	Avermectin reformatsky adducts
US4895837A (en)	1988-01-29	1990-01-23	Merck & Co., Inc.	Avermectin derivatives
US4906619A (en) *	1988-07-22	1990-03-06	Merck & Co., Inc.	Alkyl avermectin derivatives
US5030622A (en) *	1989-06-02	1991-07-09	Merck & Co., Inc.	Avermectin derivatives
JP2888586B2 (en)	1990-03-05	1999-05-10	社団法人北里研究所	Microorganism for selective production of specific components of avermectin and its selective production method
US5169839A (en) *	1990-05-11	1992-12-08	Merck & Co., Inc.	Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
CA2052860A1 (en) *	1990-10-11	1992-04-12	Thomas L. Shih	Avermectin degradation products and derivatives
US5208222A (en)	1991-03-28	1993-05-04	Merck & Co., Inc.	4"-and 4'-alkylthio avermectin derivatives
US5229415A (en) *	1992-03-24	1993-07-20	Merck & Co., Inc.	Alkylthio alkyl avermectins are active antiparasitic agents
JPH0633273A (en)	1992-07-16	1994-02-08	Asahi Chem Ind Co Ltd	Rust preventive for metal part embedded in alc
GB9312154D0 (en) *	1993-06-12	1993-07-28	Pfizer Ltd	Antiparasitic agents
GB9316129D0 (en)	1993-08-04	1993-09-22	Pfizer Ltd	Antiprasatic agents
US5362863A (en) *	1993-09-29	1994-11-08	Merck & Co., Inc.	Process for the preparation of 4"-amino avermectin compounds
GB9402916D0 (en) *	1994-02-16	1994-04-06	Pfizer Ltd	Antiparasitic agents
NZ514026A (en) *	1999-02-09	2001-09-28	Kitasato Inst	A vermectin derivatives

2001
- 2001-08-08 US US10/343,972 patent/US20040087519A1/en not_active Abandoned
- 2001-08-08 AU AU2001278694A patent/AU2001278694A1/en not_active Abandoned
- 2001-08-08 CA CA2418975A patent/CA2418975C/en not_active Expired - Fee Related
- 2001-08-08 JP JP2002518223A patent/JPWO2002012248A1/en active Pending
- 2001-08-08 WO PCT/JP2001/006803 patent/WO2002012248A1/en not_active Ceased
2004
- 2004-11-29 US US10/997,869 patent/US7250402B2/en not_active Expired - Fee Related
2011
- 2011-12-05 JP JP2011265938A patent/JP5439464B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US7250402B2 (en)	2007-07-31
US20050148520A1 (en)	2005-07-07
CA2418975C (en)	2012-01-17
US20040087519A1 (en)	2004-05-06
JP5439464B2 (en)	2014-03-12
WO2002012248A1 (en)	2002-02-14
JPWO2002012248A1 (en)	2004-01-15
CA2418975A1 (en)	2003-02-07
JP2012097092A (en)	2012-05-24

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