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AU2001283857A1 - Synthetic oxygen transport made from cross-linked modified human or porcine haemoglobin with improved properties, method for a preparation thereof from purifiedmaterial and use thereof - Google Patents

Synthetic oxygen transport made from cross-linked modified human or porcine haemoglobin with improved properties, method for a preparation thereof from purifiedmaterial and use thereof

Info

Publication number
AU2001283857A1
AU2001283857A1 AU2001283857A AU8385701A AU2001283857A1 AU 2001283857 A1 AU2001283857 A1 AU 2001283857A1 AU 2001283857 A AU2001283857 A AU 2001283857A AU 8385701 A AU8385701 A AU 8385701A AU 2001283857 A1 AU2001283857 A1 AU 2001283857A1
Authority
AU
Australia
Prior art keywords
cross
preparation
purifiedmaterial
improved properties
modified human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001283857A
Inventor
Wolfgang Barnikol
Oswald Burkhard
Stephanie Dinkelmann
Ulrike Domack
Bernd Fiedler
Birgit Manz
Harald Potzschke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanguibiotech AG
Original Assignee
Sanguibiotech AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanguibiotech AG filed Critical Sanguibiotech AG
Publication of AU2001283857A1 publication Critical patent/AU2001283857A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

According to the claims, the present invention comprises the preparation of chemically modified, cross-linked hemoglobins with improved functional properties, the cross-linked hemoglobins prepared according to this method and the use of these hemoglobins as artificial oxygen carriers. The synthesis method is characterized by technical simplicity as well as by high yields.
AU2001283857A 2000-06-29 2001-06-12 Synthetic oxygen transport made from cross-linked modified human or porcine haemoglobin with improved properties, method for a preparation thereof from purifiedmaterial and use thereof Abandoned AU2001283857A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10031740A DE10031740A1 (en) 2000-06-29 2000-06-29 Artificial oxygen carriers from cross-linked modified human or pig hemoglobin with improved properties, processes for their technically simple production from purified material in high yields, and their use
DE10031740 2000-06-29
PCT/EP2001/006613 WO2002000230A1 (en) 2000-06-29 2001-06-12 Synthetic oxygen transport made from cross-linked modified human or porcine haemoglobin with improved properties, method for a preparation thereof from purified material and use thereof

Publications (1)

Publication Number Publication Date
AU2001283857A1 true AU2001283857A1 (en) 2002-01-08

Family

ID=7647244

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001283857A Abandoned AU2001283857A1 (en) 2000-06-29 2001-06-12 Synthetic oxygen transport made from cross-linked modified human or porcine haemoglobin with improved properties, method for a preparation thereof from purifiedmaterial and use thereof

Country Status (7)

Country Link
US (1) US7005414B2 (en)
EP (1) EP1294386B1 (en)
AT (1) ATE345806T1 (en)
AU (1) AU2001283857A1 (en)
DE (2) DE10031740A1 (en)
ES (1) ES2275712T3 (en)
WO (1) WO2002000230A1 (en)

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US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
DE10031744A1 (en) * 2000-06-29 2002-01-17 Sanguibio Tech Ag Mammalian hemoglobins compatible with blood plasma, crosslinked and conjugated with polyalkylene oxides as artificial medical oxygen carriers, their production and their use
DE20017940U1 (en) 2000-10-19 2000-12-28 MAP Medizintechnik für Arzt und Patient GmbH & Co KG, 82152 Planegg Breathing mask for supplying a breathing gas to a mask user and a derivation device for deriving breathing gas
DE10201682A1 (en) 2002-01-17 2003-07-31 Map Medizin Technologie Gmbh The breathing mask arrangement
WO2003035156A2 (en) 2001-10-22 2003-05-01 Map Medizin-Technologie Gmbh Breathing mask device and application device and frontal support device thereof
DE10151984C5 (en) * 2001-10-22 2008-07-17 Map Medizin-Technologie Gmbh Application device for a breathing mask arrangement
DE10220992A1 (en) * 2002-05-11 2003-12-04 Sanguibiotech Ag Use of one or more oxygen carriers selected from hemoglobin, myoglobin and derivatives thereof for the treatment of an organ dysfunction due to an acute lack of supply and for the treatment / prevention of tissue damage due to such a disorder
EP1545673B1 (en) * 2002-09-06 2013-12-18 ResMed Limited Forehead pad for respiratory mask
DE10352692A1 (en) * 2003-11-12 2005-06-23 Sanguibiotech Gmbh Use of hypo-oncotic solutions in the blood of addable, hyperpolymeric hemoglobins for the treatment of pulmonary edema
EP1765443B1 (en) 2004-06-16 2019-01-02 ResMed Limited Respiratory mask assembly with a pivotable forehead support that can be moved to accommodate facial cushions having different depths
WO2008086794A2 (en) 2007-01-21 2008-07-24 Hemoteq Ag Medical product for treating stenosis of body passages and for preventing threatening restenosis
US9192697B2 (en) * 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
DE102008027133A1 (en) * 2008-05-30 2009-12-03 Ls Medcap Gmbh Fully synthetic albumin analog
ES2550634T3 (en) 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Use of nanocrystals for a drug delivery balloon
US10080821B2 (en) * 2009-07-17 2018-09-25 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
WO2011081712A1 (en) * 2009-12-31 2011-07-07 Boston Scientific Scimed, Inc. Cryo activated drug delivery and cutting balloons
ES2370221B1 (en) * 2010-05-20 2012-08-16 Universidad De Huelva ATTRACTING COMPOSITION FOR FOREST INSECTS.
US20120028899A1 (en) * 2010-07-30 2012-02-02 Andre Francis Palmer Composition and process for synthesizing tense and relaxed state polymerized hemoglobin
US8609815B2 (en) 2010-09-02 2013-12-17 Sangart, Inc. Methods for preparing stable deoxygenated PEG-hemoglobin conjugate solutions comprising an antioxidant
WO2012031236A1 (en) 2010-09-02 2012-03-08 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
PL2550973T3 (en) 2011-07-23 2014-03-31 Sastomed Gmbh Wound spray
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
EP2614833A1 (en) 2012-01-13 2013-07-17 SastoMed GmbH Scarring reducing wound treatment
MX358784B (en) 2012-04-03 2018-09-04 Sangart Inc Succinimide-activated nitroxyl compounds and methods for the use thereof for nitroxylation of proteins.
EP2968597B1 (en) 2013-03-15 2021-08-18 Schindler, William Polyalkylene oxide valerate hemoglobin conjugates
DE102013014651A1 (en) 2013-09-03 2015-03-05 Sanguibiotech Gmbh Preparations for improved tissue oxygenation by peritoneal ventilation
EP3092213B1 (en) 2013-12-27 2019-10-23 Virginia Commonwealth University Allosteric hemoglobin modifiers with nitric oxide releasing moiety
EP3421044A1 (en) 2017-06-26 2019-01-02 SastoMed GmbH Oxygen carriers for the treatment of skin indispositions
JP7387597B2 (en) 2017-07-18 2023-11-28 ヴァーテック・バイオ・インコーポレイテッド Blood substitute containing hemoglobin and production method

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US4001401A (en) 1975-02-02 1977-01-04 Alza Corporation Blood substitute and blood plasma expander comprising polyhemoglobin
US4001200A (en) 1975-02-27 1977-01-04 Alza Corporation Novel polymerized, cross-linked, stromal-free hemoglobin
DE2616086C2 (en) 1976-04-13 1986-04-03 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg Substance for use in a colloidal blood volume substitute made from hydroxyethyl starch and hemoglobin
US4179637A (en) 1978-04-14 1979-12-18 Santora James V Incandescent light bulb with multiple filaments providing multiple lives
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EP0854151A1 (en) 1997-01-20 1998-07-22 SanguiBioTech AG Process for the preparation of uniform fractions of hyperpolymers of haemoglobin

Also Published As

Publication number Publication date
WO2002000230A1 (en) 2002-01-03
EP1294386A1 (en) 2003-03-26
DE10031740A1 (en) 2002-02-14
EP1294386B1 (en) 2006-11-22
DE50111495D1 (en) 2007-01-04
US7005414B2 (en) 2006-02-28
ES2275712T3 (en) 2007-06-16
US20040029780A1 (en) 2004-02-12
ATE345806T1 (en) 2006-12-15

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