AU2001280764A1 - Drug delivery system for enhanced bioavailability of hydrophobic active ingredients - Google Patents
Drug delivery system for enhanced bioavailability of hydrophobic active ingredientsInfo
- Publication number
- AU2001280764A1 AU2001280764A1 AU2001280764A AU8076401A AU2001280764A1 AU 2001280764 A1 AU2001280764 A1 AU 2001280764A1 AU 2001280764 A AU2001280764 A AU 2001280764A AU 8076401 A AU8076401 A AU 8076401A AU 2001280764 A1 AU2001280764 A1 AU 2001280764A1
- Authority
- AU
- Australia
- Prior art keywords
- delivery system
- drug delivery
- active ingredients
- hydrophobic active
- enhanced bioavailability
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000004480 active ingredient Substances 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- 230000002209 hydrophobic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09635234 | 2000-08-09 | ||
| US09/635,234 US6531158B1 (en) | 2000-08-09 | 2000-08-09 | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
| PCT/US2001/023401 WO2002011699A1 (en) | 2000-08-09 | 2001-07-26 | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001280764A1 true AU2001280764A1 (en) | 2002-02-18 |
Family
ID=24546994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001280764A Abandoned AU2001280764A1 (en) | 2000-08-09 | 2001-07-26 | Drug delivery system for enhanced bioavailability of hydrophobic active ingredients |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US6531158B1 (en) |
| AU (1) | AU2001280764A1 (en) |
| TW (1) | TWI285116B (en) |
| WO (1) | WO2002011699A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL130602A0 (en) | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
| KR20030076715A (en) * | 2001-03-01 | 2003-09-26 | 그레랑 파마수티컬 가부시키가이샤 | Fenofibrate containing composition |
| WO2003082247A2 (en) * | 2002-03-26 | 2003-10-09 | Teva Pharmaceutical Industries Ltd. | Drug microparticles |
| AU2003263480A1 (en) * | 2002-09-24 | 2004-04-19 | Ranbaxy Laboratories Limited | Oral pharmaceutical compositions of fenofibrate having high bioavailability |
| CN100473378C (en) * | 2002-12-17 | 2009-04-01 | 阿伯特有限及两合公司 | Formulations comprising fenofibric acid, physiologically acceptable salts or derivatives thereof |
| EP1829541A1 (en) * | 2002-12-17 | 2007-09-05 | Abbott GmbH & Co. KG | Formulation comprising fenofibric acid or a physiologically acceptable salt thereof |
| BE1015641A4 (en) * | 2003-05-26 | 2005-07-05 | Mariani Jean Paul | Micronization 70. |
| EP1559419A1 (en) * | 2004-01-23 | 2005-08-03 | Fournier Laboratories Ireland Limited | Pharmaceutical formulations comprising metformin and a fibrate, and processes for their obtention |
| JP5449780B2 (en) | 2006-01-20 | 2014-03-19 | オキュラス イノヴェイティヴ サイエンシズ、インコーポレイテッド | Method for treating or preventing inflammation and hypersensitivity using redox potential aqueous solution |
| CA2644905A1 (en) * | 2006-03-06 | 2007-09-13 | Teva Pharmaceutical Industries Ltd. | Ezetimibe compositions |
| SI2029110T1 (en) * | 2006-06-06 | 2012-01-31 | Tibotec Pharm Ltd | Process for preparing spray dried formulations of tmc125 |
| RU2009102262A (en) * | 2006-06-26 | 2010-08-10 | Мьючуал Фармасьютикал Компани, Инк. (Us) | COMPOSITIONS OF ACTIVE AGENT, WAYS OF THEIR OBTAINING AND WAYS OF APPLICATION |
| CA2673419A1 (en) * | 2006-12-21 | 2008-06-26 | Alphapharm Pty Ltd | Pharmaceutical composition |
| WO2008104846A2 (en) * | 2007-02-26 | 2008-09-04 | Wockhardt Research Centre | Pharmaceutical compositions of fenofibrate |
| US9180110B2 (en) | 2007-02-26 | 2015-11-10 | Wockhardt Ltd. | Pharmaceutical compositions of fenofibrate |
| WO2009042114A2 (en) | 2007-09-21 | 2009-04-02 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
| JP2012500221A (en) | 2008-08-15 | 2012-01-05 | ディポメド,インコーポレイティド | Gastric retentive pharmaceutical composition for treatment and prevention of CNS disorders |
| US20100159010A1 (en) * | 2008-12-24 | 2010-06-24 | Mutual Pharmaceutical Company, Inc. | Active Agent Formulations, Methods of Making, and Methods of Use |
| WO2010078429A1 (en) * | 2008-12-30 | 2010-07-08 | Impax Laboratories, Inc. | Pharmaceutical dosage forms and methods of manufacturing same |
| FR2943539B1 (en) * | 2009-03-31 | 2011-07-22 | Ethypharm Sa | PHARMACEUTICAL COMPOSITION COMPRISING A IMMUNOSUPPRESSIVE MACROLIDE OF THE LIMUS FAMILY. |
| MX386504B (en) | 2009-06-15 | 2025-03-19 | Sanfer Farma S A P I De C V | SOLUTION CONTAINING HYPOCHLOROUS ACID AND METHODS FOR USING SAME. |
| KR101202994B1 (en) * | 2010-04-12 | 2012-11-21 | 한미사이언스 주식회사 | Oral pharmaceutical composition comprising fenofibric acid and an alkalifying agent |
| WO2014091318A1 (en) | 2012-12-11 | 2014-06-19 | Lupin Atlantis Holdings, S.A. | Reduced dose pharmaceutical compositions of fenofibrate |
| EP3609474A4 (en) * | 2017-04-13 | 2021-01-27 | Pharmako Biotechnologies PTY Limited | DISTRIBUTION SYSTEM FOR CHEMICALS DISPERSIBLE IN COLD WATER |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3639637A (en) | 1968-04-23 | 1972-02-01 | Richardson Merrell Inc | Water dispersible diethylstilbestrol compositions |
| US4013785A (en) | 1975-03-21 | 1977-03-22 | Bristol-Myers Company | Apap tablet containing fumed silica and process for manufacturing same |
| GB1579818A (en) | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
| US4153678A (en) * | 1978-07-17 | 1979-05-08 | American Cyanamid Company | Levamisole effervescent tablets |
| US4344934A (en) * | 1978-11-20 | 1982-08-17 | American Home Products Corporation | Therapeutic compositions with enhanced bioavailability |
| FR2494112B1 (en) | 1980-11-19 | 1986-01-10 | Laruelle Claude | |
| DE3107933A1 (en) | 1981-03-02 | 1982-09-16 | Cassella Ag, 6000 Frankfurt | SUBSTITUTED 3-AMINO-SYDNONIMINE, METHOD FOR THE PRODUCTION AND USE THEREOF |
| DE3247118A1 (en) | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | NEW SUBSTITUTED 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT |
| FR2557459B1 (en) | 1984-01-02 | 1986-05-30 | Lhd Lab Hygiene Dietetique | POLYCAPROLACTONE-BASED INERT MATRIX FOR ORAL ADMINISTRATION OF A MEDICAMENT, AND METHOD FOR PREPARING THE GALENIC FORM COMPRISING THE SAME |
| US4721709A (en) | 1984-07-26 | 1988-01-26 | Pyare Seth | Novel pharmaceutical compositions containing hydrophobic practically water-insoluble drugs adsorbed on pharmaceutical excipients as carrier; process for their preparation and the use of said compositions |
| EP0179583A1 (en) | 1984-10-04 | 1986-04-30 | Merck & Co. Inc. | A system for enhancing the water dissolution rate and solubility of poorly soluble drugs |
| WO1987000428A1 (en) | 1985-07-24 | 1987-01-29 | Pyare Seth | Oxazepam containing pharmaceutical composition |
| US4716033A (en) | 1986-03-27 | 1987-12-29 | Warner-Lambert Company | Medicament adsorbates with surfactant and their preparation |
| FR2602423B1 (en) | 1986-08-08 | 1989-05-05 | Ethypharm Sa | PROCESS FOR THE PREPARATION OF A FENOFIBRATE-BASED MEDICINAL PRODUCT, OBTAINED BY THIS PROCESS |
| US4859703A (en) | 1987-06-15 | 1989-08-22 | Warner-Lambert Company | Lipid regulating compositions |
| FR2627696B1 (en) * | 1988-02-26 | 1991-09-13 | Fournier Innovation Synergie | NEW GALENIC FORM OF FENOFIBRATE |
| SE8803935L (en) * | 1988-10-31 | 1990-05-01 | Kabivitrum Ab | LAEKEMEDELSKOMPOSITION |
| US5228400A (en) * | 1991-07-30 | 1993-07-20 | Luke William J | Planting tool |
| TW355683B (en) * | 1994-02-17 | 1999-04-11 | Janssen Pharmaceutica Nv | Composition containing micronized nebivolol |
| US5948438A (en) | 1995-01-09 | 1999-09-07 | Edward Mendell Co., Inc. | Pharmaceutical formulations having improved disintegration and/or absorptivity |
| US5545628A (en) * | 1995-01-10 | 1996-08-13 | Galephar P.R. Inc. | Pharmaceutical composition containing fenofibrate |
| FR2737121B1 (en) | 1995-07-27 | 1997-10-03 | Cl Pharma | NEW GALENIC FORMULATIONS OF FENOFIBRATE AND THEIR APPLICATIONS |
| US5769934A (en) | 1997-01-15 | 1998-06-23 | Fmc Corporation | Method for producing microcrystalline cellulose |
| FR2758459B1 (en) * | 1997-01-17 | 1999-05-07 | Pharma Pass | FENOFIBRATE PHARMACEUTICAL COMPOSITION HAVING HIGH BIODAVAILABILITY AND PROCESS FOR PREPARING THE SAME |
| CA2214895C (en) * | 1997-09-19 | 1999-04-20 | Bernard Charles Sherman | Improved pharmaceutical composition comprising fenofibrate |
| FR2774591B1 (en) * | 1998-02-12 | 2000-05-05 | Lipha | PHARMACEUTICAL COMPOSITION COMPRISING THE ASSOCIATION OF METFORMIN AND FIBRATE AND THE USE THEREOF FOR THE PREPARATION OF MEDICINES FOR REDUCING HYPERGLYCEMIA |
| AP1224A (en) * | 1998-03-19 | 2003-11-14 | Bristol Myers Squibb Co | Biphasic controlled release delivery system for high solubility pharmaceuticals and method. |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| CA2270306C (en) * | 1999-04-27 | 2000-09-26 | Bernard Charles Sherman | Pharmaceutical compositions comprising co-micronized fenofibrate |
-
2000
- 2000-08-09 US US09/635,234 patent/US6531158B1/en not_active Expired - Fee Related
-
2001
- 2001-07-26 AU AU2001280764A patent/AU2001280764A1/en not_active Abandoned
- 2001-07-26 WO PCT/US2001/023401 patent/WO2002011699A1/en not_active Ceased
- 2001-08-01 TW TW090118724A patent/TWI285116B/en not_active IP Right Cessation
-
2002
- 2002-11-21 US US10/300,808 patent/US20030138496A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030138496A1 (en) | 2003-07-24 |
| WO2002011699A1 (en) | 2002-02-14 |
| TWI285116B (en) | 2007-08-11 |
| US6531158B1 (en) | 2003-03-11 |
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